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Haplotype Search Result
Total result: 1567
| Reference | Markers
|
Haplotype | Related Gene(s)/Region(s)
|
Statistical Values | Author Comments | Result Category
|
|---|---|---|---|---|---|---|
| Gutierrez, B.,2001 | [HTR2C_GT(12-18)/CT(4-5)] - (HTR2C_Cys23Ser) | HTR2C | Haplotype analysis:c...... Haplotype analysis:chi sauqre test, allele P-value > 0.05 More... | No significant assoc...... No significant association was observed in BD. More... | Negative | |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 10-A allele 10-A | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=1/0, chi square=1, P-value = 0.317311 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 1-A allele 1-A | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=20/39, chi square=6.12, P-value = 0.013376 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 1-G allele 1-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=8/8, chi square=0, P-value = 1 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 2-A allele 2-A | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=0/1, chi square=1, P-value = 0.317311 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 2-G allele 2-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=6/8, chi square=0.29, P-value = 0.59298 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 3-A allele 3-A | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=8/18, chi square=3.85, P-value = 0.04986 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 3-G allele 3-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=73/36, chi square=12.56, P-value = 0.000394 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 4-A allele 4-A | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=0/4, chi square=4, P-value = 0.0455 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 4-G allele 4-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=12/14, chi square=0.15, P-value = 0.694887 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 5-G allele 5-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=2/2, chi square=0, P-value = 1 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 7-G allele 7-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=1/1, chi square=0, P-value = 1 More... | No significant asso...... No significant association was found . More... | Negative |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | C-C-A C-C-A | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.95, OR (95% CI)=1.076(0.112-10.38) More... | No significant asso...... No significant association was found . More... | Negative |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | C-T-A C-T-A | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.626, OR (95% CI)=0.732(0.214-2.531) More... | No significant asso...... No significant association was found . More... | Negative |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | C-T-G C-T-G | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.092, OR (95% CI)=2.477(0.892-7.139) More... | No significant asso...... No significant association was found . More... | Negative |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | G-C-A G-C-A | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.023, OR (95% CI)=4.251(1.225-14.75) More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | G-C-G G-C-G | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.803, OR (95% CI)=0.834(0.196-3.537) More... | No significant asso...... No significant association was found . More... | Negative |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | G-T-A G-T-A | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.027, OR (95% CI)=1.890(1.074-3.325) More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | G-T-G G-T-G | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.033, OR (95% CI)=3.797(1.123-12.43) More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Lin, Y. M., 2007 | TPH1_G-346T - rs4570625 - rs11178997 - rs11178998 | G/T, non T-A-G G/T, non T-A-G | TPH1 TPH2 | P-value = 0.32, OR (...... P-value = 0.32, OR (95% CI)=0.84 (0.59-1.19) More... | Negative | |
| Lin, Y. M., 2007 | TPH1_G-346T - rs4570625 - rs11178997 - rs11178998 | G/T, T-A-G G/T, T-A-G | TPH1 TPH2 | P-value = 0.08, OR (...... P-value = 0.08, OR (95% CI)=2.40 (0.90-6.35) More... | Negative | |
| Lin, Y. M., 2007 | TPH1_-346T - rs4570625 - rs11178997 - rs11178998 | T, T-A-G T, T-A-G | TPH1 TPH2 | P-value = 0.22, OR (...... P-value = 0.22, OR (95% CI)=1.68 (0.72-3.89) More... | The risk for BPD was...... The risk for BPD was only 1.68 times greater if the individual carrying the TPH2 risk haplotype had a TPH1-347T allele, and the difference between the 2 subgroups was not significant More... | Negative |
| Lin, Y. M., 2007 | TPH1_-346G - rs4570625 - rs11178997 - rs11178998 | G, T-A-G G, T-A-G | TPH1 TPH2 | P-value < 0.001, ...... P-value < 0.001, OR (95% CI)=4.81 (2.62-8.83) More... | Of those with the TP...... Of those with the TPH2 TAG haplotype, the risk was 4.81 times greater for individuals who also had the TPH1-346G allele More... | Positive |
| Korner, J.,1994 | TH - PJ4.7 - TY7 | TH4 - PJ4.7 - TY7 TH4 - PJ4.7 - TY7 | TH | p-value = 0.083 p-value = 0.083 | There is no linkage ...... There is no linkage disequilibrium in either group. More... | Negetive |
| Abou Jamra, R.,2007 | STR15-1002 - D2S381 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.59; STRs on 2q as conditional markers, interaction NPL score=3.84 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | STR15-1002 - D2S2950 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=6; STRs on 2q as conditional markers, interaction NPL score=3.5 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | STR15-1002 - D2S2334 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.89; STRs on 2q as conditional markers, interaction NPL score=3.52 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | STR15-1002 - D2S222 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.62; STRs on 2q as conditional markers, interaction NPL score=3.77 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | STR15-1002 - D2S1399 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.62; STRs on 2q as conditional markers, interaction NPL score=3.86 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Green, E. K.,2005 | SNP8NRG221533 - microsatellites478B14848 - microsatellites420M91395 | NRG1 | Haplotypic associati...... Haplotypic association: for Bipolar(n=529), P-value = 0.04, OR (95% CI)=1.37(1.03-1.80); for Bipolar-P(n=329), P-value = 0.11, OR (95% CI)=1.34(0.94-1.90); for Bipolar-I(n=193), P-value = 0.009, OR (95% CI)=1.71(1.29-2.59); for Bipolar-I(n=95), P-value = 0.01, OR (95% CI)=1.95(1.11-3.41); for Bipolar-NI(n=336), P-value = 0.33, OR (95% CI)=1.19(0.82-1.72) More... | We found a significa...... We found a significant difference in haplotype distribution between bipolar cases and controls globally and specifically for the core haplotype. More... | Positive | |
| Thomson, P. A., 2007 | SNP8NRG221533 - rs4298458 - SNP8NRG241930 - SNP8NRG243177 | NRG1 | P-value = 0.0045 for...... P-value = 0.0045 for BP More... | In the BP sample, a ...... In the BP sample, a four-SNP haplotype was nominally significant at the individual level More... | Positive | |
| Etain, B., 2010 | SNAP25_promoter_SNP1 - rs6039769 - rs2076239 - rs362987 | GAAA GAAA | SNAP25 | P-value = 0.002 for ...... P-value = 0.002 for 'GAAA' haplotype More... | have significant P-v...... have significant P-values in early onset subgroup More... | Positive |
| Ikeda, M., 2006 | SLC6A4_5HTTVNTR - rs3813034 | SLC6A4 | global P-value = 0.8...... global P-value = 0.878 More... | We found no associat...... We found no association with BP in the haplotype-wise association analysis. More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 1-1-1-1-1-1-1-1 1-1-1-1-1-1-1-1 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.181, OR (95% CI)=1.34 (0.89-2.01) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 2-1-1-1-1-1-1-1 2-1-1-1-1-1-1-1 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.475, OR (95% CI)=1.27 (0.73-2.22) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 1-1-2-2-1-1-2-2 1-1-2-2-1-1-2-2 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 1, OR (95% CI)=1.06 (0.47-2.39) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 2-1-2-2-1-1-2-2 2-1-2-2-1-1-2-2 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.359, OR (95% CI)=0.60 (0.23-1.54) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 1-1-1-1-2-1-2-2 1-1-1-1-2-1-2-2 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.793, OR (95% CI)=1.15 (0.40-3.34) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 2-1-1-1-2-1-2-2 2-1-1-1-2-1-2-2 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.037, OR (95% CI)=0.27 (0.08-0.99) More... | Further analysis usi...... Further analysis using the RelRisk program indicated that the haplotype (i.e. 21112122) was associated with a significant protective effect. More... | Positive |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 2-1-2-2-1-1-1-1 2-1-2-2-1-1-1-1 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.756, OR (95% CI)=0.76 (0.21-2.73) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 2-2-1-1-1-2-1-1 2-2-1-1-1-2-1-1 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.293, OR (95% CI)=0.37 (0.07-1.88) More... | Negative | |
| Rees, M., 1997 | SLC6A4 _intron 2_VNTR_5HTTLPR | 12 allele-deleted al...... 12 allele-deleted allele More... | SLC6A4 | P-value = 0.0001, es...... P-value = 0.0001, estimated disequilibrium constant, D = 0.055 More... | The disequilibrium w...... The disequilibrium was highly statistically significant but of only modest effect size. More... | Positive |
| Palo, O. M.,2010 | rs994367 - rs560764 | A-C A-C | LINGO2 | Haplotypic associati...... Haplotypic association:Z-score=1.306, FBAT P-value = 0.191 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs960232 - rs2076902 | A-G A-G | ADAMTSL1 | Haplotypic associati...... Haplotypic association:Z-score=-1.288, FBAT P-value = 0.197 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs954779 - rs735741 | G-A G-A | RNF38, SHB, MIR3159 | Haplotypic associati...... Haplotypic association:Z-score=-0.891, FBAT P-value = 0.373 More... | No significant asso...... No significant association was found . More... | Negative |
| Kahler, A. K., 2010 | rs937605 - rs524897 | CT CT | PDE4B | individual P-value =...... individual P-value = 0.0056, OR(95% CI)=1.93(1.24-2.99), global P-value = 0.035 More... | the strongest nomina...... the strongest nominally associated More... | Positive |
| Palo, O. M.,2010 | rs923784 - rs2026349 | G-C G-C | PGM5 | Haplotypic associati...... Haplotypic association:Z-score=0.92, FBAT P-value = 0.357 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs916691 - rs1013920 | T-C T-C | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=1.894, FBAT P-value = 0.058 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs9103 - rs994367 | A-A A-A | C9orf72, LINGO2 | Haplotypic associati...... Haplotypic association:Z-score=1.794, FBAT P-value = 0.072 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs887882 - rs1024761 | G-G G-G | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=1.778, FBAT P-value = 0.075 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs885993 - rs1896887 | G-G G-G | CFTR | Haplotypic associati...... Haplotypic association:Z-score=-1.328, FBAT P-value = 0.184 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs885451 - rs944700 | G-A G-A | DNAJB5 | Haplotypic associati...... Haplotypic association:Z-score=1.823, FBAT P-value = 0.068 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs868053 - rs12217 | A-G A-G | CPED1, AASS | Haplotypic associati...... Haplotypic association:Z-score=2.013, FBAT P-value = 0.044 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs855543 - rs471371 | G-A G-A | UBE2R2 | Haplotypic associati...... Haplotypic association:Z-score=2.099, FBAT P-value = 0.035 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs7817 - rs43077 | A-G A-G | IFRD1 | Haplotypic associati...... Haplotypic association:Z-score=-1.958, FBAT P-value = 0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs757099 - rs1220087 | A-G A-G | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-1.978, FBAT P-value = 0.047 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs748530 - rs717081 | G-A G-A | SLC24A2 | Haplotypic associati...... Haplotypic association:Z-score=0.657, FBAT P-value = 0.511 More... | No significant asso...... No significant association was found . More... | Negative |
| Pickard, B. S., 2006 | rs7479743 - rs6589832 - rs7925270 - rs3133855 | GRIK4 | P-value = 0.094 betw...... P-value = 0.094 between SCZ cases and controls; P-value = 0.712 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs7479743 - rs6589832 - rs7925270 - rs3133855 | C-G-C-T C-G-C-T | GRIK4 | P-value = 0.008 P-value = 0.008 | Positive | |
| Pickard, B. S., 2006 | rs7479743 - rs6589832 - rs7925270 | GRIK4 | P-value = 0.239 betw...... P-value = 0.239 between BPD cases and controls; P-value = 0.718 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs7479743 - rs6589832 | GRIK4 | P-value = 0.538 betw...... P-value = 0.538 between BPD cases and controls; P-value = 0.779 between all cases and controls More... | Negative | ||
| Pae, C. U., 2008 | rs7452939 - rs6903874 - rs6937506 | TAAR6 | Global X<sup>2...... Global X<sup>2</sup>=28.69, df=3, P-value = 0.00001 More... | There were significa...... There were significant global differences in haplotype frequency between BID patients compared to controls. More... | Positive | |
| Pae, C. U., 2008 | rs7452939 - rs6903874 - rs6937506 | GCT GCT | TAAR6 | X<sup>2</su...... X<sup>2</sup>=17.80, df=1, P-value = 0.00002 More... | The GCT haplotype wa...... The GCT haplotype was significantly over-represented in the patients with BID compared to controls. More... | Positive |
| Pae, C. U., 2008 | rs7452939 - rs6903874 - rs6937506 | GTT GTT | TAAR6 | X<sup>2</su...... X<sup>2</sup>=11.46, df=1, P-value = 0.001 More... | The GTT haplotype wa...... The GTT haplotype was significantly under-represented in patients with BID compared to controls More... | Positive |
| Palo, O. M.,2010 | rs735741 - rs1138374 | G-G G-G | SHB, MIR3159 | Haplotypic associati...... Haplotypic association:Z-score=0.308, FBAT P-value = 0.758 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs719530 - rs214459 | C-A C-A | IMMP2L | Haplotypic associati...... Haplotypic association:Z-score=1.81, FBAT P-value = 0.07 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs717081 - rs1332184 | G-G G-G | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=1.178, FBAT P-value = 0.238 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs716933 - rs1004604 | T-A T-A | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-2.655, FBAT P-value = 0.007 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs702223 - rs1332677 | C-A C-A | ELAVL2 | Haplotypic associati...... Haplotypic association:Z-score=-1.342, FBAT P-value = 0.179 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs671018 - rs855543 | G-A G-A | TOPORS-AS1, NDUFB6 | Haplotypic associati...... Haplotypic association:Z-score=-2.776, FBAT P-value = 0.005 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs666478 - rs1555454 | G-A G-A | TEK | Haplotypic associati...... Haplotypic association:Z-score=3.218, FBAT P-value = 0.001 More... | Significant associat...... Significant association was found. More... | Positive |
| Goes, F. S., 2009 | rs6651144 - rs7005606 | T-G T-G | NRG1 | Haplotype Associatio...... Haplotype Association:FBAT:individual P-value = 0.048(Standard BP), 0.0052(Psychotic BP), 0.1149(Mood-incongruent psychotic BP); global P-value = 0.1283(Standard BP), 0.0066(Psychotic BP), 0.0898(Mood-incongruent psychotic BP) More... | Association was obse...... Association was observed in both standard BP and Psychotic BP. More... | Positive |
| Shi, J., 2008 (d) | rs6442925 - rs714359 - rs16965644 | DEC1 CRY1 NR1D1 | FDR-cutoff P-value =...... FDR-cutoff P-value = 1.77E 06; FITF P-value = 8.88E 06 More... | Negative | ||
| Shi, J., 2008 (d) | rs6442925 - rs534654 - rs1534891 | DEC1 TMEM165 CSNK1E | FDR-cutoff P-value =...... FDR-cutoff P-value = 1.77E 06; FITF P-value = 1.72E 06 More... | A significant multi-...... A significant multi-locus interaction between rs6442925 in BHLHB2, rs1534891 in CSNK1E, and rs534654 near 3' of CLOCK gene was identified in Sample II, which remained significant after correction for multiple testing using a false discovery rate method. More... | Positive | |
| Shi, J., 2008 (d) | rs6442925 - rs534654 - rs135757 | DEC1 TMEM165 CSNK1E | FDR-cutoff P-value =...... FDR-cutoff P-value = 1.77E 06; FITF P-value = 2.62E 05 More... | Negative | ||
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | C-C-C C-C-C | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value = 0.37 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | C-C-T C-C-T | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value = 0.031 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | C-T-C C-T-C | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value = 0.72 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | C-T-T C-T-T | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value = 0.019 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | G-C-C G-C-C | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value < 0.0001 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | G-C-T G-C-T | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value = 0.11 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | G-T-C G-T-C | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value < 0.0001 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Gutierrez-Fernandez, A., 2014 | rs62510682 - rs6994992 | G-T G-T | NRG1 | All patients: X...... All patients: X2=1.818, P-value=0.6451, P-value(uncorrected)=0.1776; Bipolar disorder patients: X2=1.382, P-value=0.7058, P-value(uncorrected)=0.2397. More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Gutierrez-Fernandez, A., 2014 | rs62510682 - rs6994992 | G-C G-C | NRG1 | All patients: X...... All patients: X2=1.529, P-value=0.7545, P-value(uncorrected)=0.2163; Bipolar disorder patients: X2=1.329, P-value=0.6522, P-value(uncorrected)=0.2018. More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Gutierrez-Fernandez, A., 2014 | rs62510682 - rs6994992 | T-C T-C | NRG1 | All patients: X...... All patients: X2=0.132, P-value=0.9985, P-value(uncorrected)=0.7162; Bipolar disorder patients: X2=0.006, P-value=1, P-value(uncorrected)=0.9398. More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Jamain, S., 2014 | rs624097 - rs316762 - rs10512793 | OXCT1 PLCXD3 | Pmeta=2.6...... Pmeta=2.6E-07 More... | A more significant d...... A more significant difference between patients and controls was observed on chromosome 5p13 for the combination of rs624097-rs316762-rs10512793, for which an overall Pmeta=2.6E-07 was observed. More... | Trend | |
| Nissen, S.,2012 | rs5756339 - rs4821523 - rs2009667 | T-A-G T-A-G | IFT27 | TDT:T = 6.803,U = 30...... TDT:T = 6.803,U = 30.62,chi square = 15.16,P-value = 0.00000889 for Family merged More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Palo, O. M.,2010 | rs560764 - rs1018254 | C-G C-G | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=1.234, FBAT P-value = 0.217 More... | No significant asso...... No significant association was found . More... | Negative |
| Kahler, A. K., 2010 | rs558325 - rs1040716 - rs11803904 - rs12142015 | PDE4B | global P-value = 0.0...... global P-value = 0.0057 More... | the best overall 4-S...... the best overall 4-SNP result, but none of the individual haplotypes displayed association with disease More... | Positive | |
| Nissen, S.,2012 | rs4821523 - rs2009667 - rs5756342 - rs9607382 - rs2413421 | A-G-C-G-G A-G-C-G-G | IFT27 | TDT:T = 3.57,U = 27....... TDT:T = 3.57,U = 27.93,chi square = 18.84,P-value = 0.0000142 for Family phase 2 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Nissen, S.,2012 | rs4821523 - rs2009667 - rs5756342 - rs9607382 | A-G-C-G A-G-C-G | IFT27 | TDT:T = 7.405,U = 33...... TDT:T = 7.405,U = 33.05,chi square = 16.25,P-value = 0.0000554 for Family phase 2 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Nissen, S.,2012 | rs4821523 - rs2009667 - rs5756342 | A-G-C A-G-C | IFT27 | TDT:T = 7.619,U = 32...... TDT:T = 7.619,U = 32.44,chi square = 15.38,P-value = 0.0000879 for Family phase 2;T = 8.633,U = 37.14,chi square = 17.76,P-value = 0.0000251 for Family merged More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Palo, O. M.,2010 | rs471371 - rs885451 | G-C G-C | UBE2R2, DNAJB5 | Haplotypic associati...... Haplotypic association:Z-score=-1.808, FBAT P-value = 0.07 More... | No significant asso...... No significant association was found . More... | Negative |
| Goes, F. S., 2009 | rs4476964 - NRG241930 - NRG2243177 - rs7819063 | G-G-T-T G-G-T-T | NRG1 | Haplotype Associatio...... Haplotype Association:FBAT:individual P-value = 0.0256(Standard BP), 0.0013(Psychotic BP), 0.1605(Mood-incongruent psychotic BP); global P-value = 0.0583(Standard BP), 0.0071(Psychotic BP), 0.1316(Mood-incongruent psychotic BP) More... | Association was obse...... Association was observed in both standard BP and Psychotic BP. More... | Positive |
| Palo, O. M.,2010 | rs43077 - rs2040587 | G-G G-G | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=2.222, FBAT P-value = 0.026 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs41736 - rs885993 | G-C G-C | MET, CFTR | Haplotypic associati...... Haplotypic association:Z-score=1.557, FBAT P-value = 0.119 More... | No significant asso...... No significant association was found . More... | Negative |
| Lee, H. J., 2013 | rs41453448 - rs1125777 - rs12568010 | G-C-A G-C-A | NFIA | P-value=2.12E-07, OR...... P-value=2.12E-07, OR=0.427 More... | Haplotype constructi...... Haplotype construction using flanking three SNPs (rs41453448, rs1125777, and rs12568010) spanning 7549bp showed a more significant association. More... | Trend |
| Palo, O. M.,2010 | rs41261 - rs176481 | A-G A-G | CDHR3 | Haplotypic associati...... Haplotypic association:Z-score=2.768, FBAT P-value = 0.005 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs38831 - rs1510504 | C-G C-G | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=1.694, FBAT P-value = 0.09 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs37742 - rs1476517 | A-A A-A | IMMP2L DOCK4 | Haplotypic associati...... Haplotypic association:Z-score=0.639, FBAT P-value = 0.523 More... | No significant asso...... No significant association was found . More... | Negative |
| Fatjo-Vilas, M., 2016 | rs3763180 - rs1048432 - rs4960155 - rs9379002 - rs9405890 - rs1475157 | T-C-C-T-C-A T-C-C-T-C-A | NRN1 | P(unadj)-value=0.000...... P(unadj)-value=0.000031 More... | On the contrary, the...... On the contrary, the haplotype T-C-C-T-C-A (Block 3: SNP6-SNP11) had higher frequencies in controls. Results in Block 3 also remained significant after multiple testing and could be interpreted as reflecting a protective effect of this haplotype. More... | Positive |
| Nissen, S.,2012 | rs3484 - rs736720 - rs2284026 | A-G-A A-G-A | PVALB | Case control replica...... Case control replication:chi square = 18.34,global P-value = 0.00255;chi square = 13.76,individual P-value = 0.000207 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Palo, O. M.,2010 | rs288886 - rs671018 | G-G G-G | TOPORS-AS1, NDUFB6 | Haplotypic associati...... Haplotypic association:Z-score=-2.202, FBAT P-value = 0.027 More... | Significant associat...... Significant association was found. More... | Positive |
| Lyons-Warren, A.,2005 | rs278124 - rs278109 - rs203368 - rs435136 | C-G-A-C C-G-A-C | CIT | Haplotypic associati...... Haplotypic association:FBAT, under-transmitted, individual P-value = 0.026 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Lyons-Warren, A.,2005 | rs278124 - rs278109 - rs203368 | C-G-A C-G-A | CIT | Haplotypic associati...... Haplotypic association:FBAT, under-transmitted, individual P-value = 0.03 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Zandi, P. P., 2007 | rs2673555 - rs1901090 | KCNQ3 | P-value = 0.003 P-value = 0.003 | A two-SNP haplotype ...... A two-SNP haplotype in KCNQ3 (rs2673555-rs1901090) was associated at P=0.003 More... | Positive | |
| Palo, O. M.,2010 | rs263645 - rs960232 | T-A T-A | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-1.713, FBAT P-value = 0.086 More... | No significant asso...... No significant association was found . More... | Negative |
| Shi, J., 2008 (b) | rs2597758 - rs1031326 - rs744731 - rs2597778 | AGGA AGGA | QDPR | Gene-wide significan...... Gene-wide significant haplotypic association with bipolar disorder: TDT P-value = 0.0064, Gene-wide P-value = 0.0499 More... | Gene-wide significan...... Gene-wide significant haplotypic associations with BP, none of these associations survived correction for multiple testing More... | Positive |
| Palo, O. M.,2010 | rs257376 - rs1858929 | G-A G-A | PRKAR2B, SLC26A4 | Haplotypic associati...... Haplotypic association:Z-score=-1.605, FBAT P-value = 0.108 More... | No significant asso...... No significant association was found . More... | Negative |
| McHugh, P. C.,2009 | rs2421095 - rs1876487 | A-A, A-A A-A, A-A | SPR | X<sup>2</su...... X<sup>2</sup> test:for Bipolar I disorder, OR(95%CI)=0.68(0.09-5.24), P>0.05; for any bipolar disorder, OR(95%CI)=1.70(0.66-4.41), P>0.05; for any mood disorder, OR(95%CI)=0.94(0.40-2.24), P>0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| McHugh, P. C.,2009 | rs2421095 - rs1876487 | A-A, A-G A-A, A-G | SPR | X<sup>2</su...... X<sup>2</sup> test:for Bipolar I disorder, OR(95%CI)=5.47(1.68-17.88), P0.005; for any bipolar disorder, OR(95%CI)=3.68(1.36-9.95), P0.01; for any mood disorder, OR(95%CI)=7.84(1.03-59.58), P0.047 More... | Association was obse...... Association was observed in both BPI group and any bipolar disorder group. More... | Positive |
| McHugh, P. C.,2009 | rs2421095 - rs1876487 | C-A, A-A C-A, A-A | SPR | X<sup>2</su...... X<sup>2</sup> test:for Bipolar I disorder, OR(95%CI)=0.54(0.21-1.44), P>0.05; for any bipolar disorder, OR(95%CI)=0.76(0.44-1.32), P>0.05; for any mood disorder, OR(95%CI)=1.06(0.70-1.61), P>0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| McHugh, P. C.,2009 | rs2421095 - rs1876487 | C-A, A-G C-A, A-G | SPR | X<sup>2</su...... X<sup>2</sup> test:for Bipolar I disorder, OR(95%CI)=1.81(0.81-4.03), P>0.05; for any bipolar disorder, OR(95%CI)=1.42(0.82-2.44), P>0.05; for any mood disorder, OR(95%CI)=0.59(0.38-0.92), P0.019 More... | No significant asso...... No significant association was found . More... | Negative |
| McHugh, P. C.,2009 | rs2421095 - rs1876487 | C-A, C-A C-A, C-A | SPR | X<sup>2</su...... X<sup>2</sup> test:for Bipolar I disorder, OR(95%CI)=0.69(0.34-1.43), P>0.05; for any bipolar disorder, OR(95%CI)=0.70(0.44-1.10), P>0.05; for any mood disorder, OR(95%CI)=1.17(0.81-1.67), P>0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs234 - rs41261 | A-A A-A | CDHR3 | Haplotypic associati...... Haplotypic association:Z-score=2.688, FBAT P-value = 0.007 More... | Significant associat...... Significant association was found. More... | Positive |
| Emily, M.,2009 | rs2237091 - rs1798011 | PDGFRB KITLG | SNP-SNP interaction ...... SNP-SNP interaction analysis:allelic X<sup>2</sup> test:Marginal effect 1, Pval=0.86, RR=1.01; Marginal effect 2, Pval=0.69, RR=1.02; Interaction test, P-value = 1.13E-09 More... | Significant associat...... Significant association was found. More... | Positive | |
| Palo, O. M.,2010 | rs2169325 - rs1128957 | C-A C-A | TUSC1 | Haplotypic associati...... Haplotypic association:Z-score=-1.505, FBAT P-value = 0.132 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs214468 - rs37742 | A-A A-A | IMMP2L | Haplotypic associati...... Haplotypic association:Z-score=0.639, FBAT P-value = 0.523 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs214459 - rs214468 | A-G A-G | IMMP2L | Haplotypic associati...... Haplotypic association:Z-score=1.304, FBAT P-value = 0.192 More... | No significant asso...... No significant association was found . More... | Negative |
| Shi, J., 2008 (d) | rs2137947 - rs6850524 - rs1534891 | DEC1 CLOCK CSNK1E | FDR-cutoff P-value =...... FDR-cutoff P-value = 1.77E 06; FITF P-value = 7.59E 05 More... | Negative | ||
| Palo, O. M.,2010 | rs2076902 - rs748530 | G-G G-G | ADAMTSL1, SLC24A2 | Haplotypic associati...... Haplotypic association:Z-score=0.343, FBAT P-value = 0.731 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs2040587 - rs2056865 | A-G A-G | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=-2.183, FBAT P-value = 0.029 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs2026349 - rs1414944 | A-G A-G | PIP5K1B | Haplotypic associati...... Haplotypic association:Z-score=-0.844, FBAT P-value = 0.398 More... | No significant asso...... No significant association was found . More... | Negative |
| Nissen, S.,2012 | rs2009667 - rs3484 - rs736720 | A-G-G A-G-G | IFT27, PVALB | Case control replica...... Case control replication:chi square = 22.97,global P-value = 0.000343;chi square = 10.76,individual P-value = 0.00105 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Nissen, S.,2012 | rs2009667 - rs3484 - rs736720 | G-A-G G-A-G | IFT27, PVALB | Case control replica...... Case control replication:chi square = 22.97,global P-value = 0.000343;chi square = 9.81,individual P-value = 0.00174 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Xiang, B., 2013 | rs1928038 - rs1475196 - rs9562689 - rs9567747 - rs1328684 - rs1328684 | C-A-G-A-G-G C-A-G-A-G-G | HTR2A | P-value=0.29, X<s...... P-value=0.29, X<sup>2</sup>=1.16 More... | This haplotype is no...... This haplotype is not significantly associated with BP. More... | Negative |
| Xiang, B., 2013 | rs1928038 - rs1475196 - rs9562689 - rs9567747 - rs1328684 - rs1328684 | C-A-A-G-A-A C-A-A-G-A-A | HTR2A | P-value=0.03, X<s...... P-value=0.03, X<sup>2</sup>=5.08 More... | We found that haplot...... We found that haplotypes with multiple-markers (SNPs rs1928038-rs1475196-rs9562689-rs9567747-rs1328684-rs1328684) showed significant association with BPD-I, with a global P value of 0.003, and three specific haplotypes (CAAGAA, GAGGAA, and CCGAAA) with corrected P values of <0.05. More... | Positive |
| Xiang, B., 2013 | rs1928038 - rs1475196 - rs9562689 - rs9567747 - rs1328684 - rs1328684 | G-A-G-G-A-A G-A-G-G-A-A | HTR2A | P-value=0.02, X<s...... P-value=0.02, X<sup>2</sup>=5.74 More... | We found that haplot...... We found that haplotypes with multiple-markers (SNPs rs1928038-rs1475196-rs9562689-rs9567747-rs1328684-rs1328684) showed significant association with BPD-I, with a global P value of 0.003, and three specific haplotypes (CAAGAA, GAGGAA, and CCGAAA) with corrected P values of <0.05. More... | Positive |
| Xiang, B., 2013 | rs1928038 - rs1475196 - rs9562689 - rs9567747 - rs1328684 - rs1328684 | C-C-G-A-A-A C-C-G-A-A-A | HTR2A | P-value=0.03, X<s...... P-value=0.03, X<sup>2</sup>=4.71 More... | We found that haplot...... We found that haplotypes with multiple-markers (SNPs rs1928038-rs1475196-rs9562689-rs9567747-rs1328684-rs1328684) showed significant association with BPD-I, with a global P value of 0.003, and three specific haplotypes (CAAGAA, GAGGAA, and CCGAAA) with corrected P values of <0.05. More... | Positive |
| Xiang, B., 2013 | rs1928038 - rs1475196 - rs9562689 - rs9567747 - rs1328684 - rs1328684 | C-A-G-A-A-A C-A-G-A-A-A | HTR2A | P-value=0.10, X<s...... P-value=0.10, X<sup>2</sup>=2.69 More... | This haplotype is no...... This haplotype is not significantly associated with BP. More... | Negative |
| Palo, O. M.,2010 | rs1896887 - rs38831 | G-C G-C | CFTR | Haplotypic associati...... Haplotypic association:Z-score=1.295, FBAT P-value = 0.195 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1889915 - rs1074670 | G-G G-G | TRPM3 | Haplotypic associati...... Haplotypic association:Z-score=1.73, FBAT P-value = 0.083 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1880180 - rs1121030 | A-G A-G | SLC13A1 | Haplotypic associati...... Haplotypic association:Z-score=0.592, FBAT P-value = 0.554 More... | No significant asso...... No significant association was found . More... | Negative |
| Gonzalez, R., 2015 | rs1868049 - rs3789327 - rs11022778 | G-A-A G-A-A | ARNTL | P-value=2.99E-03 P-value=2.99E-03 | The global ARNTL hap...... The global ARNTL haploblock permutation test was significantly associated with BD. More... | Positive |
| Palo, O. M.,2010 | rs1858929 - rs2028030 | G-G G-G | SLC26A4 | Haplotypic associati...... Haplotypic association:Z-score=0.504, FBAT P-value = 0.614 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1833083 - rs996867 | A-A A-A | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=0.608, FBAT P-value = 0.542 More... | No significant asso...... No significant association was found . More... | Negative |
| McGrath, C. L.,2009 | rs17684881 - rs17612218 - rs11144020 - rs17612778 - rs17612874 - rs17691363 - rs10869430 | RORB | haplotype(C-G-C-C-C-...... haplotype(C-G-C-C-C-A-G):P-value = 5.08E-05, Permuted P-value < 0.001 More... | Association was obse...... Association was observed only in the case-control sample. More... | Positive | |
| Houlihan, L.M.,2009 | rs17408391 - rs10939038 | PI4K2B | haplotype analysis:g...... haplotype analysis:global P-value > 0.005 in the bipolar disorder sample More... | No statistically sig...... No statistically significant association was found in the bipolar disorder sample. More... | Negative | |
| Shi, J., 2008 (b) | rs1568447 - rs690533 - rs516035 | GGA GGA | GRIN2C | Gene-wide significan...... Gene-wide significant haplotypic association with bipolar disorder: TDT P-value = 0.0110, Gene-wide P-value = 0.0410 More... | Gene-wide significan...... Gene-wide significant haplotypic associations with BP, none of these associations survived correction for multiple testing More... | Positive |
| Palo, O. M.,2010 | rs1555454 - rs9103 | A-G A-G | TEK, C9orf72 | Haplotypic associati...... Haplotypic association:Z-score=0.434, FBAT P-value = 0.664 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1510504 - rs846427 | A-C A-C | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=-1.224, FBAT P-value = 0.221 More... | No significant asso...... No significant association was found . More... | Negative |
| Soler, J., 2016 | rs1507754 - rs10917670 - rs951436 - rs951439 - rs2661319 | T-T-G-G-A T-T-G-G-A | RGS4 | P(unadj)-value=0.030...... P(unadj)-value=0.030, OR(CI95%) = 0.33 (0.12–0.98) More... | The haplotype TTGGA ...... The haplotype TTGGA of RGS4 was found to be under-transmitted to patients. However, this result did not remain significant after multiple test correction. More... | |
| Palo, O. M.,2010 | rs1476878 - rs257376 | G-A G-A | PRKAR2B | Haplotypic associati...... Haplotypic association:Z-score=2.409, FBAT P-value = 0.016 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs1476517 - rs7817 | G-G G-G | DOCK4 IFRD1 | Haplotypic associati...... Haplotypic association:Z-score=1.419, FBAT P-value = 0.155 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1475656 - rs1412340 | A-A A-A | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-2.063, FBAT P-value = 0.039 More... | Significant associat...... Significant association was found. More... | Positive |
| Zandi, P. P., 2007 | rs1457485 - rs4377991 - rs1870126 - rs765847 | ST3GAL1 | P-value = 0.003 P-value = 0.003 | a four-SNP haplotype...... a four-SNP haplotype in the gene desert (rs1457485-rs4377991-rs1870126-rs765847) was associated at P=0.003 More... | Positive | |
| Palo, O. M.,2010 | rs1414944 - rs1889915 | A-G A-G | PIP5K1B, TRPM3 | Haplotypic associati...... Haplotypic association:Z-score=0.801, FBAT P-value = 0.423 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1414237 - rs1360590 | G-G G-G | CDKN2B-AS1 | Haplotypic associati...... Haplotypic association:Z-score=1.392, FBAT P-value = 0.163 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1412340 - rs288886 | G-A G-A | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=2.404, FBAT P-value = 0.016 More... | Significant associat...... Significant association was found. More... | Positive |
| Kandaswamy R., 2014 | rs1400166 - rs2875257 - rs10510353 - rs11708019 - rs1963265 - rs1508724 - rs9823996 - rs11710946 - rs6769814 | GRM7 | P-value=0.007 P-value=0.007 | The most significant...... The most significant haplotype (HAP_GRM7) associated with BP comprising SNPs rs1400166, rs2875257, rs10510353, rs11708019, rs1963265, rs1508724, rs9823996, rs11710946, and rs6769814 (P=0.007) was less common in cases compared to controls (2.2% and 4.3% in cases and controls, respectively). More... | Positive | |
| Palo, O. M.,2010 | rs1360590 - rs1327063 | A-C A-C | CDKN2B-AS1 | Haplotypic associati...... Haplotypic association:Z-score=-1.709, FBAT P-value = 0.087 More... | No significant asso...... No significant association was found . More... | Negative |
| Khan, R. A., 2016 | rs13396535-rs6717029-rs13410341-rs6755392 | T-C-C-A T-C-C-A | ZEB2 | P(unadj)-value=1.56E...... P(unadj)-value=1.56E−04, P-value=7.79E−04 More... | Two haplotypes, one ...... Two haplotypes, one for block rs10197694-rs6430057-rs10928212-rs1427298-13,389,578 (CTAGT: P=0.007, P corrected=0.036) and one for block rs13396535-rs6717029-rs13410341-rs6755392 (TCCA: P=1.56E−04, P corrected=7.79E−04),were significantly associated with BPD. More... | |
| Palo, O. M.,2010 | rs1332677 - rs2169325 | G-C G-C | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-1.482, FBAT P-value = 0.138 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1327063 - rs702223 | C-C C-C | ELAVL2 | Haplotypic associati...... Haplotypic association:Z-score=-2.184, FBAT P-value = 0.028 More... | Significant associat...... Significant association was found. More... | Positive |
| Nissen, S.,2012 | rs129336 - rs130566 - rs5756339 - rs4821523 | C-C-T-A C-C-T-A | IFT27 | TDT:T = 11.49,U = 39...... TDT:T = 11.49,U = 39.48,chi square = 15.37,P-value = 0.0000885 for Family phase 2 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Ross, K. A.,2011 | rs12227938 - rs9551988 | PSPC1 | SNP interactions:P-v...... SNP interactions:P-value = 0.38 More... | No significant asso...... No significant association was found . More... | Negative | |
| Ross, K. A.,2011 | rs12227938 - rs4850057 | SNP interactions:P-v...... SNP interactions:P-value = 0.39 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Ross, K. A.,2011 | rs12227938 - rs2122231 | SNP interactions:P-v...... SNP interactions:P-value = 0.9 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Ross, K. A.,2011 | rs12227938 - (SNP A-1797773) | SNP interactions:P-v...... SNP interactions:P-value = 0.38 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Kalsi, G., 2006 | rs1194031 - AY070435_29818-insT - AY070435_307CA1 | AY070435 | global P-value = 0.0...... global P-value = 0.0079 More... | The most significant...... The most significant three-marker haplotype was found when combining data from markers rs1190431, 29818-insT, and 307CA1 (empirical p= 0.0079). More... | Positive | |
| Palo, O. M.,2010 | rs1138374 - rs716933 | G-A G-A | SHB | Haplotypic associati...... Haplotypic association:Z-score=3.23, FBAT P-value = 0.001 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs1128957 - rs757099 | C-A C-A | TUSC1 | Haplotypic associati...... Haplotypic association:Z-score=-1.505, FBAT P-value = 0.132 More... | No significant asso...... No significant association was found . More... | Negative |
| McGrath, C. L.,2009 | rs11144033 - rs3903529 - rs968357 | RORB | haplotype(G-A-T):P-v...... haplotype(G-A-T):P-value = 8.92E-05, Permuted P-value = 0.002 More... | Association was obse...... Association was observed only in the case-control sample. More... | Positive | |
| Houlihan, L.M.,2009 | rs10939038 - rs3756207 | PI4K2B | haplotype analysis:g...... haplotype analysis:global P-value > 0.005 in the bipolar disorder sample More... | No statistically sig...... No statistically significant association was found in the bipolar disorder sample. More... | Negative | |
| Palo, O. M.,2010 | rs1074670 - rs1404195 | G-A G-A | TRPM3 | Haplotypic associati...... Haplotypic association:Z-score=2.147, FBAT P-value = 0.031 More... | Significant associat...... Significant association was found. More... | Positive |
| Khan, R. A., 2016 | rs10197694-rs6430057-rs10928212-rs1427298-13,389,578 | C-T-A-G-T C-T-A-G-T | ZEB2 | P(unadj)-value=0.007...... P(unadj)-value=0.007, P-value=0.036 More... | Two haplotypes, one ...... Two haplotypes, one for block rs10197694-rs6430057-rs10928212-rs1427298-13,389,578 (CTAGT: P=0.007, P corrected=0.036) and one for block rs13396535-rs6717029-rs13410341-rs6755392 (TCCA: P=1.56E−04, P corrected=7.79E−04),were significantly associated with BPD. More... | |
| Palo, O. M.,2010 | rs1018254 - rs1475656 | G-T G-T | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=1.012, FBAT P-value = 0.311 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1013920 - rs719530 | A-A A-A | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=-0.952, FBAT P-value = 0.341 More... | No significant asso...... No significant association was found . More... | Negative |
| Hu, X.,2010 | rs10124883 - rs6004133 | ASTN2 PI4KA | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 6.49E-12 for WTCCC data, P-value = 0.027 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10124883 - rs178069 | ASTN2 SNAP29 | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 5.37E-12 for WTCCC data, P-value = 0.031 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10124883 - rs165730 | ASTN2 PI4KA | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.038 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10124883 - rs165596 | ASTN2 SNAP29 | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.035 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10123629 - rs6004133 | ASTN2 PI4KA | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.026 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10123629 - rs178069 | ASTN2 SNAP29 | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.021 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10123629 - rs165730 | ASTN2 PI4KA | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.085 for replication study(Chinese sample). More... | No significant asso...... No significant association was found . More... | Negative | |
| Hu, X.,2010 | rs10123629 - rs165596 | ASTN2 SNAP29 | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.132 for replication study(Chinese sample). More... | No significant asso...... No significant association was found . More... | Negative | |
| Cordeiro, Q.,2005 | RGS4_SNP1 - RGS4_SNP4 - RGS4_SNP17 - RGS4_SNP18 | G-G-G-G G-G-G-G | RGS4 | Haplotypic associati...... Haplotypic association:Family-based analysis:TDT:X<sup>2</sup>=7.12, P-value = 0.007 in BD; Linkage disequilibrium analyses:haplotypes G-G-G-G and A-T-A-A for all four SNPs accounted for over 81% of all estimated haplotypes among the controls. Two-point LD analysis showed that D'-values exceeded 0.85 for all combinations of SNPs among the cases and controls. More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Abou Jamra, R.,2005(a) | PRODH2026 - PRODH1945 - PRODH1482 | PRODH | Haplotypic associati...... Haplotypic association:Global P-value = 0.903(based on 100, 000 replications) for BPAD. More... | No significant asso...... No significant association was found . More... | Negative | |
| Abou Jamra, R.,2005(a) | PRODH2026 - PRODH1945 | PRODH | Haplotypic associati...... Haplotypic association:Global P-value = 0.755(based on 100, 000 replications) for BPAD. More... | No significant asso...... No significant association was found . More... | Negative | |
| Abou Jamra, R.,2005(a) | PRODH1945 - PRODH1482 | PRODH | Haplotypic associati...... Haplotypic association:Global P-value = 0.804(based on 100, 000 replications) for BPAD. More... | No significant asso...... No significant association was found . More... | Negative | |
| Borsotto, M., 2007 | PPP2R2C_Intron5_24-257/320 - PPP2R2C_Intron5_99-24175/218 | (24-257/320)-(99-241...... (24-257/320)-(99-24175/218) More... | PPP2R2C | the risk haplotype f...... the risk haplotype for 24-257/320 and 99-24175/218 is 'AA' in the Labimo collection, no P-value given in the original text More... | an individual carryi...... an individual carrying the haplotype 'AA' at biallelic markers 24-257/320 and 99-24175/218 presents an increased risk of developing BD. More... | Positive |
| Borsotto, M., 2007 | PPP2R2C_Intron1d_99-24169/139 - PPP2R2C_Intron4_24-247/216 | (99-24169/139)-(24-2...... (99-24169/139)-(24-247/216) More... | PPP2R2C | the risk haplotype f...... the risk haplotype for 99-24169/139 and 24-247/216 is 'AG' in the UCL collection, no P-value given in the original text More... | an individual carryi...... an individual carrying the haplotype 'AG' at biallelic markers 99-24169/139 and 24-247/216 presents an increased risk of developing BD. More... | Positive |
| Goes, F. S., 2009 | NRG241930 - NRG2243177 - rs7819063 | G-T-T G-T-T | NRG1 | Haplotype Associatio...... Haplotype Association:FBAT:individual P-value = 0.0174(Standard BP), 0.0007(Psychotic BP), 0.163(Mood-incongruent psychotic BP); global P-value = 0.0182(Standard BP), 0.0016(Psychotic BP), 0.0983(Mood-incongruent psychotic BP) More... | Association was obse...... Association was observed in both standard BP and Psychotic BP. More... | Positive |
| Goes, F. S., 2009 | NRG2243177 - rs7819063 | T-T T-T | NRG1 | Haplotype Associatio...... Haplotype Association:FBAT:individual P-value = 0.0126(Standard BP), 0.0004(Psychotic BP), 0.1508(Mood-incongruent psychotic BP); global P-value = 0.0462(Standard BP), 0.0039(Psychotic BP), 0.5529(Mood-incongruent psychotic BP) More... | Association was obse...... Association was observed in both standard BP and Psychotic BP. More... | Positive |
| Cassidy, F., 2006 | NRG1_SNP8NRG243177 - NRG1_478B14-848 | 1-2 1-2 | NRG1 | TDT P-value = 0.17, ...... TDT P-value = 0.17, X<sup>2</sup>=1.9, global P-value = 0.78, global X<sup>2</sup>=4.76, df=8 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Negative |
| Cassidy, F., 2006 | NRG1_SNP8NRG221533 - NRG1_SNP8NRG243177 - NRG1_478B14-848 - NRG1_420M9-1395 | 1-1-2-3 1-1-2-3 | NRG1 | TDT P-value = 0.1, X...... TDT P-value = 0.1, X<sup>2</sup>=2.71, global P-value = 0.48, global X<sup>2</sup>=5.52, df=6 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD. A haplotype comprised of alleles from the three microsatellite markers (M3-M4-M5) did exhibit a marginal association which was not significant at the global haplotype level. More... | Negative |
| Cassidy, F., 2006 | NRG1_SNP8NRG221533 - NRG1_SNP8NRG243177 | 2-2 2-2 | NRG1 | TDT P-value = 0.91, ...... TDT P-value = 0.91, X<sup>2</sup>=0.01, global P-value = 0.89, global X<sup>2</sup>=0.23, df=2 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Negative |
| Cassidy, F., 2006 | NRG1_SNP8NRG221533 - NRG1_478B14-848 - NRG1_420M9-1395 | 2-2-3 2-2-3 | NRG1 | TDT P-value = 0.79, ...... TDT P-value = 0.79, X<sup>2</sup>=0.07, global P-value = 0.49, global X<sup>2</sup>=5.44, df=6 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Negative |
| Cassidy, F., 2006 | NRG1_478B14-848 - NRG1_420M9-1395 - NRG1_D8S1810 | 1-3-5 1-3-5 | NRG1 | TDT P-value = 0.04, ...... TDT P-value = 0.04, X<sup>2</sup>=4.23, global P-value = 0.31, global X<sup>2</sup>=7.15, df=6 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Positive |
| Cassidy, F., 2006 | NRG1_478B14-848 - NRG1_420M9-1395 | 1-3 1-3 | NRG1 | TDT P-value = 0.14, ...... TDT P-value = 0.14, X<sup>2</sup>=2.13, global P-value = 0.53, global X<sup>2</sup>=5.07, df=6 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Negative |
| Cassidy, F., 2006 | NRG1_420M9-1395 - NRG1_D8S1810 | 3-6 3-6 | NRG1 | TDT P-value = 0.9, X...... TDT P-value = 0.9, X<sup>2</sup>=0.01, global P-value = 0.69, global X<sup>2</sup>=3.91, df=6 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Negative |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | c-a-g c-a-g | NOS3 | P-value = 0.15, perm...... P-value = 0.15, permutation-based P-value = 0.515, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). More... | Negative |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | c-a-t c-a-t | NOS3 | P-value = 0.003, per...... P-value = 0.003, permutation-based P-value = 0.212, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). More... | Positive |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | c-b-g c-b-g | NOS3 | P-value = 0.006, per...... P-value = 0.006, permutation-based P-value = 0.022, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). The estimated c-b-g and t-a-g haplotypes were under-represented in BD patients (p=0.022, and p<0.001 respectively). More... | Positive |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | c-b-t c-b-t | NOS3 | P-value = 0.197, per...... P-value = 0.197, permutation-based P-value = 0.408, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). More... | Negative |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | t-a-g t-a-g | NOS3 | P-value = 0, permuta...... P-value = 0, permutation-based P-value < 0.001, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). The estimated c-b-g and t-a-g haplotypes were under-represented in BD patients (p=0.022, and p<0.001 respectively). After correction for multiple testing, the frequencies differed significantly only for the estimated t-a-g haplotype. More... | Positive |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | t-b-g t-b-g | NOS3 | P-value = 0.563, per...... P-value = 0.563, permutation-based P-value = 0.052, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). Furthermore, the estimated t-b-g haplotype had a tendency to be over-represented in BD patients (p=0.052). More... | Negative |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | t-b-t t-b-t | NOS3 | P-value = 0.08, perm...... P-value = 0.08, permutation-based P-value = 0.601, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). More... | Negative |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | c-c-t c-c-t | NOS3 | P-value = 0, permuta...... P-value = 0, permutation-based P-value = 0.523, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). More... | Negative |
| Washizuka, S., 2004 | NDUFV2_-796C>G - NDUFV2_-602G>A - NDUFV2_-233T>C | NDUFV2 | global P-value = 0.0...... global P-value = 0.01 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-796C>G - NDUFV2_-602G>A | NDUFV2 | global P-value = 0.0...... global P-value = 0.002 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-602G>A - NDUFV2_-233T>CNDUFV2_86C>T | NDUFV2 | global P-value = 0.0...... global P-value = 0.001 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-602G>A - NDUFV2_-233T>C | NDUFV2 | global P-value = 0.0...... global P-value = 0.01 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-602G>A | A-A A-A | NDUFV2 | global P-value < ...... global P-value < 0.0001, individual P-value = 0.55, X<sup>2</sup>=0.34 in Japanese; global P-value = 0.01, individual P-value = 0.20, X<sup>2</sup>=1.61 in NIMH pedigrees More... | Negative | |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-602G>A | G-A G-A | NDUFV2 | global P-value < ...... global P-value < 0.0001, individual P-value < 0.0001, X<sup>2</sup>=20.35 in Japanese; global P-value = 0.01, individual P-value = 0.04, X<sup>2</sup>=4.18 in NIMH pedigrees More... | Distributions of hap...... Distributions of haplotype frequencies differed significantly between patients with BD and control subjects. Among the haplotypes, the G-G haplotype was significantly more frequently seen in BD, whereas G-A and A-G haplotypes were significantly less common in patients with BD compared with control subjects. We found significant association of the NDUFV2 haplotypes with BD in NIMH pedigrees. Two haplotypes (G-A and A-G) tended to be undertransmitted in parents-proband trios of NIMH samples. More... | Positive |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-602G>A | A-G A-G | NDUFV2 | global P-value < ...... global P-value < 0.0001, individual P-value < 0.0001, X<sup>2</sup>=23.81 in Japanese; global P-value = 0.01, individual P-value = 0.01, X<sup>2</sup>=5.59 in NIMH pedigrees More... | Distributions of hap...... Distributions of haplotype frequencies differed significantly between patients with BD and control subjects. Among the haplotypes, the G-G haplotype was significantly more frequently seen in BD, whereas G-A and A-G haplotypes were significantly less common in patients with BD compared with control subjects. We found significant association of the NDUFV2 haplotypes with BD in NIMH pedigrees. Two haplotypes (G-A and A-G) tended to be undertransmitted in parents-proband trios of NIMH samples. More... | Positive |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-602G>A | G-G G-G | NDUFV2 | global P-value = 0.0...... global P-value = 0.001, individual P-value < 0.0001, X<sup>2</sup>=10.79 in Japanese; global P-value = 0.01, individual P-value = 0.76, X<sup>2</sup>=0.08 in NIMH pedigrees More... | Distributions of hap...... Distributions of haplotype frequencies differed significantly between patients with BD and control subjects. Among the haplotypes, the G-G haplotype was significantly more frequently seen in BD, whereas G-A and A-G haplotypes were significantly less common in patients with BD compared with control subjects. More... | Positive |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-3245T>C - NDUFV2_-3041T>G | NDUFV2 | global P-value < ...... global P-value < 0.001 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-3245T>C | NDUFV2 | global P-value < ...... global P-value < 0.001 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-3245T>C - NDUFV2_-3041T>G - NDUFV2_-2694A>G | NDUFV2 | global P-value = 0.2...... global P-value = 0.28 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-3245T>C - NDUFV2_-3041T>G | NDUFV2 | global P-value = 0.0...... global P-value = 0.09 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-3041T>G - NDUFV2_-2694A>G - NDUFV2_-1020G>T | NDUFV2 | global P-value = 0.3...... global P-value = 0.30 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-3041T>G - NDUFV2_-2694A>G | NDUFV2 | global P-value = 0.0...... global P-value = 0.08 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-2694A>G - NDUFV2_-1020G>T - NDUFV2_-796C>G | NDUFV2 | global P-value = 0.1...... global P-value = 0.14 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-2694A>G - NDUFV2_-1020G>T | NDUFV2 | global P-value = 0.2...... global P-value = 0.25 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-233T>C - NDUFV2_86C>T | NDUFV2 | global P-value = 0.7...... global P-value = 0.70 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-1020G>T - NDUFV2_-796C>G - NDUFV2_-602G>A | NDUFV2 | global P-value = 0.0...... global P-value = 0.009 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-1020G>T - NDUFV2_-796C>G | NDUFV2 | global P-value = 0.6...... global P-value = 0.64 More... | Negative | ||
| Kazuno, A. A.,2009 | mtDNA_haplogroup_N9a | mtDNA | logistic regression ...... logistic regression analysis:P<0.05 using haplogroup D4 as a reference More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Schumacher, J.,2004 | MDAAO4 - MDAAO5 - MDAAO6 | A-C-G A-C-G | DAO | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.325, individual P-value = 0.032, OR=1.29 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Schumacher, J.,2004 | MDAAO4 - MDAAO5 - MDAAO6 | A-C-T A-C-T | DAO | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.325, individual P-value = 0.459, OR=0.91 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Schumacher, J.,2004 | MDAAO4 - MDAAO5 - MDAAO6 | C-C-G C-C-G | DAO | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.325, individual P-value = 0.471, OR=0.82 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Schumacher, J.,2004 | MDAAO4 - MDAAO5 - MDAAO6 | C-T-T C-T-T | DAO | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.325, individual P-value = 0.213, OR=0.85 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | T-4 T-4 | MAOA | TDT P-value = 0.012,...... TDT P-value = 0.012, X<sup>2</sup>=6.32 More... | By the haplotype TDT...... By the haplotype TDT analysis, the T-4 haplotype was found significantly associated with bipolar disorder More... | Positive |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | G-3 G-3 | MAOA | TDT P-value = 0.117,...... TDT P-value = 0.117, X<sup>2</sup>=2.46 More... | Negative | |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | T-3 T-3 | MAOA | TDT P-value = 0.756,...... TDT P-value = 0.756, X<sup>2</sup>=0.1 More... | Negative | |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | G-4 G-4 | MAOA | TDT P-value = 0.004,...... TDT P-value = 0.004, X<sup>2</sup>=8.14 More... | Negative | |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | T-5 T-5 | MAOA | TDT P-value = 0.239,...... TDT P-value = 0.239, X<sup>2</sup>=1.39 More... | Negative | |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | T-3.5 T-3.5 | MAOA | TDT P-value = 1, X&l...... TDT P-value = 1, X<sup>2</sup>=0 More... | Negative | |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | G-5 G-5 | MAOA | TDT P-value = 0.24, ...... TDT P-value = 0.24, X<sup>2</sup>=1.39 More... | Negative | |
| Schumacher, J.,2004 | M12 - M15 - M23 - M24 | T-A-C-T T-A-C-T | DAOA | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.08, individual P-value = 0.497, OR=1.16 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Schumacher, J.,2004 | M12 - M15 - M23 - M24 | T-A-T-A T-A-T-A | DAOA | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.08, individual P-value = 0.815, OR=1.04 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Schumacher, J.,2004 | M12 - M15 - M23 - M24 |