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Haplotype Search Result
Total result: 1567
| Reference | Markers
|
Haplotype | Related Gene(s)/Region(s)
|
Statistical Values | Author Comments | Result Category
|
|---|---|---|---|---|---|---|
| Gutierrez, B.,2001 | [HTR2C_GT(12-18)/CT(4-5)] - (HTR2C_Cys23Ser) | HTR2C | Haplotype analysis:c...... Haplotype analysis:chi sauqre test, allele P-value > 0.05 More... | No significant assoc...... No significant association was observed in BD. More... | Negative | |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 10-A allele 10-A | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=1/0, chi square=1, P-value = 0.317311 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 1-A allele 1-A | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=20/39, chi square=6.12, P-value = 0.013376 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 1-G allele 1-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=8/8, chi square=0, P-value = 1 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 2-A allele 2-A | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=0/1, chi square=1, P-value = 0.317311 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 2-G allele 2-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=6/8, chi square=0.29, P-value = 0.59298 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 3-A allele 3-A | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=8/18, chi square=3.85, P-value = 0.04986 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 3-G allele 3-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=73/36, chi square=12.56, P-value = 0.000394 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 4-A allele 4-A | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=0/4, chi square=4, P-value = 0.0455 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 4-G allele 4-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=12/14, chi square=0.15, P-value = 0.694887 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 5-G allele 5-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=2/2, chi square=0, P-value = 1 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2002 | [BNDF_(GT)n] - (BNDF_val66met) | allele 7-G allele 7-G | BDNF | Haplotype analysis:T...... Haplotype analysis:TDT, T/NT=1/1, chi square=0, P-value = 1 More... | No significant asso...... No significant association was found . More... | Negative |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | C-C-A C-C-A | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.95, OR (95% CI)=1.076(0.112-10.38) More... | No significant asso...... No significant association was found . More... | Negative |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | C-T-A C-T-A | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.626, OR (95% CI)=0.732(0.214-2.531) More... | No significant asso...... No significant association was found . More... | Negative |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | C-T-G C-T-G | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.092, OR (95% CI)=2.477(0.892-7.139) More... | No significant asso...... No significant association was found . More... | Negative |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | G-C-A G-C-A | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.023, OR (95% CI)=4.251(1.225-14.75) More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | G-C-G G-C-G | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.803, OR (95% CI)=0.834(0.196-3.537) More... | No significant asso...... No significant association was found . More... | Negative |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | G-T-A G-T-A | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.027, OR (95% CI)=1.890(1.074-3.325) More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Koido, K.,2005 | WFS1-SNP684 - WFS1_SNP1185 - WFS1_SNP1832 | G-T-G G-T-G | WFS1 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.033, OR (95% CI)=3.797(1.123-12.43) More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Lin, Y. M., 2007 | TPH1_G-346T - rs4570625 - rs11178997 - rs11178998 | G/T, non T-A-G G/T, non T-A-G | TPH1 TPH2 | P-value = 0.32, OR (...... P-value = 0.32, OR (95% CI)=0.84 (0.59-1.19) More... | Negative | |
| Lin, Y. M., 2007 | TPH1_G-346T - rs4570625 - rs11178997 - rs11178998 | G/T, T-A-G G/T, T-A-G | TPH1 TPH2 | P-value = 0.08, OR (...... P-value = 0.08, OR (95% CI)=2.40 (0.90-6.35) More... | Negative | |
| Lin, Y. M., 2007 | TPH1_-346T - rs4570625 - rs11178997 - rs11178998 | T, T-A-G T, T-A-G | TPH1 TPH2 | P-value = 0.22, OR (...... P-value = 0.22, OR (95% CI)=1.68 (0.72-3.89) More... | The risk for BPD was...... The risk for BPD was only 1.68 times greater if the individual carrying the TPH2 risk haplotype had a TPH1-347T allele, and the difference between the 2 subgroups was not significant More... | Negative |
| Lin, Y. M., 2007 | TPH1_-346G - rs4570625 - rs11178997 - rs11178998 | G, T-A-G G, T-A-G | TPH1 TPH2 | P-value < 0.001, ...... P-value < 0.001, OR (95% CI)=4.81 (2.62-8.83) More... | Of those with the TP...... Of those with the TPH2 TAG haplotype, the risk was 4.81 times greater for individuals who also had the TPH1-346G allele More... | Positive |
| Korner, J.,1994 | TH - PJ4.7 - TY7 | TH4 - PJ4.7 - TY7 TH4 - PJ4.7 - TY7 | TH | p-value = 0.083 p-value = 0.083 | There is no linkage ...... There is no linkage disequilibrium in either group. More... | Negetive |
| Abou Jamra, R.,2007 | STR15-1002 - D2S381 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.59; STRs on 2q as conditional markers, interaction NPL score=3.84 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | STR15-1002 - D2S2950 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=6; STRs on 2q as conditional markers, interaction NPL score=3.5 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | STR15-1002 - D2S2334 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.89; STRs on 2q as conditional markers, interaction NPL score=3.52 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | STR15-1002 - D2S222 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.62; STRs on 2q as conditional markers, interaction NPL score=3.77 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | STR15-1002 - D2S1399 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.62; STRs on 2q as conditional markers, interaction NPL score=3.86 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Green, E. K.,2005 | SNP8NRG221533 - microsatellites478B14848 - microsatellites420M91395 | NRG1 | Haplotypic associati...... Haplotypic association: for Bipolar(n=529), P-value = 0.04, OR (95% CI)=1.37(1.03-1.80); for Bipolar-P(n=329), P-value = 0.11, OR (95% CI)=1.34(0.94-1.90); for Bipolar-I(n=193), P-value = 0.009, OR (95% CI)=1.71(1.29-2.59); for Bipolar-I(n=95), P-value = 0.01, OR (95% CI)=1.95(1.11-3.41); for Bipolar-NI(n=336), P-value = 0.33, OR (95% CI)=1.19(0.82-1.72) More... | We found a significa...... We found a significant difference in haplotype distribution between bipolar cases and controls globally and specifically for the core haplotype. More... | Positive | |
| Thomson, P. A., 2007 | SNP8NRG221533 - rs4298458 - SNP8NRG241930 - SNP8NRG243177 | NRG1 | P-value = 0.0045 for...... P-value = 0.0045 for BP More... | In the BP sample, a ...... In the BP sample, a four-SNP haplotype was nominally significant at the individual level More... | Positive | |
| Etain, B., 2010 | SNAP25_promoter_SNP1 - rs6039769 - rs2076239 - rs362987 | GAAA GAAA | SNAP25 | P-value = 0.002 for ...... P-value = 0.002 for 'GAAA' haplotype More... | have significant P-v...... have significant P-values in early onset subgroup More... | Positive |
| Ikeda, M., 2006 | SLC6A4_5HTTVNTR - rs3813034 | SLC6A4 | global P-value = 0.8...... global P-value = 0.878 More... | We found no associat...... We found no association with BP in the haplotype-wise association analysis. More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 1-1-1-1-1-1-1-1 1-1-1-1-1-1-1-1 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.181, OR (95% CI)=1.34 (0.89-2.01) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 2-1-1-1-1-1-1-1 2-1-1-1-1-1-1-1 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.475, OR (95% CI)=1.27 (0.73-2.22) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 1-1-2-2-1-1-2-2 1-1-2-2-1-1-2-2 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 1, OR (95% CI)=1.06 (0.47-2.39) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 2-1-2-2-1-1-2-2 2-1-2-2-1-1-2-2 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.359, OR (95% CI)=0.60 (0.23-1.54) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 1-1-1-1-2-1-2-2 1-1-1-1-2-1-2-2 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.793, OR (95% CI)=1.15 (0.40-3.34) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 2-1-1-1-2-1-2-2 2-1-1-1-2-1-2-2 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.037, OR (95% CI)=0.27 (0.08-0.99) More... | Further analysis usi...... Further analysis using the RelRisk program indicated that the haplotype (i.e. 21112122) was associated with a significant protective effect. More... | Positive |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 2-1-2-2-1-1-1-1 2-1-2-2-1-1-1-1 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.756, OR (95% CI)=0.76 (0.21-2.73) More... | Negative | |
| Sun, H. S., 2004 | SLC6A4_5HTTLPR - rs956304 - rs25528 - rs6354 - SLC6A4_5HTTVNTR - rs6352 - rs1042173 - rs1532042 | 2-2-1-1-1-2-1-1 2-2-1-1-1-2-1-1 | SLC6A4 | Fisher's exact test,...... Fisher's exact test, P-value = 0.293, OR (95% CI)=0.37 (0.07-1.88) More... | Negative | |
| Rees, M., 1997 | SLC6A4 _intron 2_VNTR_5HTTLPR | 12 allele-deleted al...... 12 allele-deleted allele More... | SLC6A4 | P-value = 0.0001, es...... P-value = 0.0001, estimated disequilibrium constant, D = 0.055 More... | The disequilibrium w...... The disequilibrium was highly statistically significant but of only modest effect size. More... | Positive |
| Palo, O. M.,2010 | rs994367 - rs560764 | A-C A-C | LINGO2 | Haplotypic associati...... Haplotypic association:Z-score=1.306, FBAT P-value = 0.191 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs960232 - rs2076902 | A-G A-G | ADAMTSL1 | Haplotypic associati...... Haplotypic association:Z-score=-1.288, FBAT P-value = 0.197 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs954779 - rs735741 | G-A G-A | RNF38, SHB, MIR3159 | Haplotypic associati...... Haplotypic association:Z-score=-0.891, FBAT P-value = 0.373 More... | No significant asso...... No significant association was found . More... | Negative |
| Kahler, A. K., 2010 | rs937605 - rs524897 | CT CT | PDE4B | individual P-value =...... individual P-value = 0.0056, OR(95% CI)=1.93(1.24-2.99), global P-value = 0.035 More... | the strongest nomina...... the strongest nominally associated More... | Positive |
| Palo, O. M.,2010 | rs923784 - rs2026349 | G-C G-C | PGM5 | Haplotypic associati...... Haplotypic association:Z-score=0.92, FBAT P-value = 0.357 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs916691 - rs1013920 | T-C T-C | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=1.894, FBAT P-value = 0.058 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs9103 - rs994367 | A-A A-A | C9orf72, LINGO2 | Haplotypic associati...... Haplotypic association:Z-score=1.794, FBAT P-value = 0.072 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs887882 - rs1024761 | G-G G-G | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=1.778, FBAT P-value = 0.075 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs885993 - rs1896887 | G-G G-G | CFTR | Haplotypic associati...... Haplotypic association:Z-score=-1.328, FBAT P-value = 0.184 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs885451 - rs944700 | G-A G-A | DNAJB5 | Haplotypic associati...... Haplotypic association:Z-score=1.823, FBAT P-value = 0.068 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs868053 - rs12217 | A-G A-G | CPED1, AASS | Haplotypic associati...... Haplotypic association:Z-score=2.013, FBAT P-value = 0.044 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs855543 - rs471371 | G-A G-A | UBE2R2 | Haplotypic associati...... Haplotypic association:Z-score=2.099, FBAT P-value = 0.035 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs7817 - rs43077 | A-G A-G | IFRD1 | Haplotypic associati...... Haplotypic association:Z-score=-1.958, FBAT P-value = 0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs757099 - rs1220087 | A-G A-G | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-1.978, FBAT P-value = 0.047 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs748530 - rs717081 | G-A G-A | SLC24A2 | Haplotypic associati...... Haplotypic association:Z-score=0.657, FBAT P-value = 0.511 More... | No significant asso...... No significant association was found . More... | Negative |
| Pickard, B. S., 2006 | rs7479743 - rs6589832 - rs7925270 - rs3133855 | GRIK4 | P-value = 0.094 betw...... P-value = 0.094 between SCZ cases and controls; P-value = 0.712 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs7479743 - rs6589832 - rs7925270 - rs3133855 | C-G-C-T C-G-C-T | GRIK4 | P-value = 0.008 P-value = 0.008 | Positive | |
| Pickard, B. S., 2006 | rs7479743 - rs6589832 - rs7925270 | GRIK4 | P-value = 0.239 betw...... P-value = 0.239 between BPD cases and controls; P-value = 0.718 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs7479743 - rs6589832 | GRIK4 | P-value = 0.538 betw...... P-value = 0.538 between BPD cases and controls; P-value = 0.779 between all cases and controls More... | Negative | ||
| Pae, C. U., 2008 | rs7452939 - rs6903874 - rs6937506 | TAAR6 | Global X<sup>2...... Global X<sup>2</sup>=28.69, df=3, P-value = 0.00001 More... | There were significa...... There were significant global differences in haplotype frequency between BID patients compared to controls. More... | Positive | |
| Pae, C. U., 2008 | rs7452939 - rs6903874 - rs6937506 | GCT GCT | TAAR6 | X<sup>2</su...... X<sup>2</sup>=17.80, df=1, P-value = 0.00002 More... | The GCT haplotype wa...... The GCT haplotype was significantly over-represented in the patients with BID compared to controls. More... | Positive |
| Pae, C. U., 2008 | rs7452939 - rs6903874 - rs6937506 | GTT GTT | TAAR6 | X<sup>2</su...... X<sup>2</sup>=11.46, df=1, P-value = 0.001 More... | The GTT haplotype wa...... The GTT haplotype was significantly under-represented in patients with BID compared to controls More... | Positive |
| Palo, O. M.,2010 | rs735741 - rs1138374 | G-G G-G | SHB, MIR3159 | Haplotypic associati...... Haplotypic association:Z-score=0.308, FBAT P-value = 0.758 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs719530 - rs214459 | C-A C-A | IMMP2L | Haplotypic associati...... Haplotypic association:Z-score=1.81, FBAT P-value = 0.07 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs717081 - rs1332184 | G-G G-G | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=1.178, FBAT P-value = 0.238 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs716933 - rs1004604 | T-A T-A | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-2.655, FBAT P-value = 0.007 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs702223 - rs1332677 | C-A C-A | ELAVL2 | Haplotypic associati...... Haplotypic association:Z-score=-1.342, FBAT P-value = 0.179 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs671018 - rs855543 | G-A G-A | TOPORS-AS1, NDUFB6 | Haplotypic associati...... Haplotypic association:Z-score=-2.776, FBAT P-value = 0.005 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs666478 - rs1555454 | G-A G-A | TEK | Haplotypic associati...... Haplotypic association:Z-score=3.218, FBAT P-value = 0.001 More... | Significant associat...... Significant association was found. More... | Positive |
| Goes, F. S., 2009 | rs6651144 - rs7005606 | T-G T-G | NRG1 | Haplotype Associatio...... Haplotype Association:FBAT:individual P-value = 0.048(Standard BP), 0.0052(Psychotic BP), 0.1149(Mood-incongruent psychotic BP); global P-value = 0.1283(Standard BP), 0.0066(Psychotic BP), 0.0898(Mood-incongruent psychotic BP) More... | Association was obse...... Association was observed in both standard BP and Psychotic BP. More... | Positive |
| Shi, J., 2008 (d) | rs6442925 - rs714359 - rs16965644 | DEC1 CRY1 NR1D1 | FDR-cutoff P-value =...... FDR-cutoff P-value = 1.77E 06; FITF P-value = 8.88E 06 More... | Negative | ||
| Shi, J., 2008 (d) | rs6442925 - rs534654 - rs1534891 | DEC1 TMEM165 CSNK1E | FDR-cutoff P-value =...... FDR-cutoff P-value = 1.77E 06; FITF P-value = 1.72E 06 More... | A significant multi-...... A significant multi-locus interaction between rs6442925 in BHLHB2, rs1534891 in CSNK1E, and rs534654 near 3' of CLOCK gene was identified in Sample II, which remained significant after correction for multiple testing using a false discovery rate method. More... | Positive | |
| Shi, J., 2008 (d) | rs6442925 - rs534654 - rs135757 | DEC1 TMEM165 CSNK1E | FDR-cutoff P-value =...... FDR-cutoff P-value = 1.77E 06; FITF P-value = 2.62E 05 More... | Negative | ||
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | C-C-C C-C-C | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value = 0.37 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | C-C-T C-C-T | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value = 0.031 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | C-T-C C-T-C | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value = 0.72 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | C-T-T C-T-T | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value = 0.019 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | G-C-C G-C-C | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value < 0.0001 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | G-C-T G-C-T | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value = 0.11 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Mazza, M.,2010 | rs6318 - rs2428707 - rs4272555 | G-T-C G-T-C | HTR2C | Haplotype analysis:a...... Haplotype analysis:adjusted global P-value < 0.0001, adjusted individual P-value < 0.0001 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Gutierrez-Fernandez, A., 2014 | rs62510682 - rs6994992 | G-T G-T | NRG1 | All patients: X...... All patients: X2=1.818, P-value=0.6451, P-value(uncorrected)=0.1776; Bipolar disorder patients: X2=1.382, P-value=0.7058, P-value(uncorrected)=0.2397. More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Gutierrez-Fernandez, A., 2014 | rs62510682 - rs6994992 | G-C G-C | NRG1 | All patients: X...... All patients: X2=1.529, P-value=0.7545, P-value(uncorrected)=0.2163; Bipolar disorder patients: X2=1.329, P-value=0.6522, P-value(uncorrected)=0.2018. More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Gutierrez-Fernandez, A., 2014 | rs62510682 - rs6994992 | T-C T-C | NRG1 | All patients: X...... All patients: X2=0.132, P-value=0.9985, P-value(uncorrected)=0.7162; Bipolar disorder patients: X2=0.006, P-value=1, P-value(uncorrected)=0.9398. More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Jamain, S., 2014 | rs624097 - rs316762 - rs10512793 | OXCT1 PLCXD3 | Pmeta=2.6...... Pmeta=2.6E-07 More... | A more significant d...... A more significant difference between patients and controls was observed on chromosome 5p13 for the combination of rs624097-rs316762-rs10512793, for which an overall Pmeta=2.6E-07 was observed. More... | Trend | |
| Nissen, S.,2012 | rs5756339 - rs4821523 - rs2009667 | T-A-G T-A-G | IFT27 | TDT:T = 6.803,U = 30...... TDT:T = 6.803,U = 30.62,chi square = 15.16,P-value = 0.00000889 for Family merged More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Palo, O. M.,2010 | rs560764 - rs1018254 | C-G C-G | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=1.234, FBAT P-value = 0.217 More... | No significant asso...... No significant association was found . More... | Negative |
| Kahler, A. K., 2010 | rs558325 - rs1040716 - rs11803904 - rs12142015 | PDE4B | global P-value = 0.0...... global P-value = 0.0057 More... | the best overall 4-S...... the best overall 4-SNP result, but none of the individual haplotypes displayed association with disease More... | Positive | |
| Nissen, S.,2012 | rs4821523 - rs2009667 - rs5756342 - rs9607382 - rs2413421 | A-G-C-G-G A-G-C-G-G | IFT27 | TDT:T = 3.57,U = 27....... TDT:T = 3.57,U = 27.93,chi square = 18.84,P-value = 0.0000142 for Family phase 2 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Nissen, S.,2012 | rs4821523 - rs2009667 - rs5756342 - rs9607382 | A-G-C-G A-G-C-G | IFT27 | TDT:T = 7.405,U = 33...... TDT:T = 7.405,U = 33.05,chi square = 16.25,P-value = 0.0000554 for Family phase 2 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Nissen, S.,2012 | rs4821523 - rs2009667 - rs5756342 | A-G-C A-G-C | IFT27 | TDT:T = 7.619,U = 32...... TDT:T = 7.619,U = 32.44,chi square = 15.38,P-value = 0.0000879 for Family phase 2;T = 8.633,U = 37.14,chi square = 17.76,P-value = 0.0000251 for Family merged More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Palo, O. M.,2010 | rs471371 - rs885451 | G-C G-C | UBE2R2, DNAJB5 | Haplotypic associati...... Haplotypic association:Z-score=-1.808, FBAT P-value = 0.07 More... | No significant asso...... No significant association was found . More... | Negative |
| Goes, F. S., 2009 | rs4476964 - NRG241930 - NRG2243177 - rs7819063 | G-G-T-T G-G-T-T | NRG1 | Haplotype Associatio...... Haplotype Association:FBAT:individual P-value = 0.0256(Standard BP), 0.0013(Psychotic BP), 0.1605(Mood-incongruent psychotic BP); global P-value = 0.0583(Standard BP), 0.0071(Psychotic BP), 0.1316(Mood-incongruent psychotic BP) More... | Association was obse...... Association was observed in both standard BP and Psychotic BP. More... | Positive |
| Palo, O. M.,2010 | rs43077 - rs2040587 | G-G G-G | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=2.222, FBAT P-value = 0.026 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs41736 - rs885993 | G-C G-C | MET, CFTR | Haplotypic associati...... Haplotypic association:Z-score=1.557, FBAT P-value = 0.119 More... | No significant asso...... No significant association was found . More... | Negative |
| Lee, H. J., 2013 | rs41453448 - rs1125777 - rs12568010 | G-C-A G-C-A | NFIA | P-value=2.12E-07, OR...... P-value=2.12E-07, OR=0.427 More... | Haplotype constructi...... Haplotype construction using flanking three SNPs (rs41453448, rs1125777, and rs12568010) spanning 7549bp showed a more significant association. More... | Trend |
| Palo, O. M.,2010 | rs41261 - rs176481 | A-G A-G | CDHR3 | Haplotypic associati...... Haplotypic association:Z-score=2.768, FBAT P-value = 0.005 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs38831 - rs1510504 | C-G C-G | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=1.694, FBAT P-value = 0.09 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs37742 - rs1476517 | A-A A-A | IMMP2L DOCK4 | Haplotypic associati...... Haplotypic association:Z-score=0.639, FBAT P-value = 0.523 More... | No significant asso...... No significant association was found . More... | Negative |
| Fatjo-Vilas, M., 2016 | rs3763180 - rs1048432 - rs4960155 - rs9379002 - rs9405890 - rs1475157 | T-C-C-T-C-A T-C-C-T-C-A | NRN1 | P(unadj)-value=0.000...... P(unadj)-value=0.000031 More... | On the contrary, the...... On the contrary, the haplotype T-C-C-T-C-A (Block 3: SNP6-SNP11) had higher frequencies in controls. Results in Block 3 also remained significant after multiple testing and could be interpreted as reflecting a protective effect of this haplotype. More... | Positive |
| Nissen, S.,2012 | rs3484 - rs736720 - rs2284026 | A-G-A A-G-A | PVALB | Case control replica...... Case control replication:chi square = 18.34,global P-value = 0.00255;chi square = 13.76,individual P-value = 0.000207 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Palo, O. M.,2010 | rs288886 - rs671018 | G-G G-G | TOPORS-AS1, NDUFB6 | Haplotypic associati...... Haplotypic association:Z-score=-2.202, FBAT P-value = 0.027 More... | Significant associat...... Significant association was found. More... | Positive |
| Lyons-Warren, A.,2005 | rs278124 - rs278109 - rs203368 - rs435136 | C-G-A-C C-G-A-C | CIT | Haplotypic associati...... Haplotypic association:FBAT, under-transmitted, individual P-value = 0.026 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Lyons-Warren, A.,2005 | rs278124 - rs278109 - rs203368 | C-G-A C-G-A | CIT | Haplotypic associati...... Haplotypic association:FBAT, under-transmitted, individual P-value = 0.03 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Zandi, P. P., 2007 | rs2673555 - rs1901090 | KCNQ3 | P-value = 0.003 P-value = 0.003 | A two-SNP haplotype ...... A two-SNP haplotype in KCNQ3 (rs2673555-rs1901090) was associated at P=0.003 More... | Positive | |
| Palo, O. M.,2010 | rs263645 - rs960232 | T-A T-A | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-1.713, FBAT P-value = 0.086 More... | No significant asso...... No significant association was found . More... | Negative |
| Shi, J., 2008 (b) | rs2597758 - rs1031326 - rs744731 - rs2597778 | AGGA AGGA | QDPR | Gene-wide significan...... Gene-wide significant haplotypic association with bipolar disorder: TDT P-value = 0.0064, Gene-wide P-value = 0.0499 More... | Gene-wide significan...... Gene-wide significant haplotypic associations with BP, none of these associations survived correction for multiple testing More... | Positive |
| Palo, O. M.,2010 | rs257376 - rs1858929 | G-A G-A | PRKAR2B, SLC26A4 | Haplotypic associati...... Haplotypic association:Z-score=-1.605, FBAT P-value = 0.108 More... | No significant asso...... No significant association was found . More... | Negative |
| McHugh, P. C.,2009 | rs2421095 - rs1876487 | A-A, A-A A-A, A-A | SPR | X<sup>2</su...... X<sup>2</sup> test:for Bipolar I disorder, OR(95%CI)=0.68(0.09-5.24), P>0.05; for any bipolar disorder, OR(95%CI)=1.70(0.66-4.41), P>0.05; for any mood disorder, OR(95%CI)=0.94(0.40-2.24), P>0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| McHugh, P. C.,2009 | rs2421095 - rs1876487 | A-A, A-G A-A, A-G | SPR | X<sup>2</su...... X<sup>2</sup> test:for Bipolar I disorder, OR(95%CI)=5.47(1.68-17.88), P0.005; for any bipolar disorder, OR(95%CI)=3.68(1.36-9.95), P0.01; for any mood disorder, OR(95%CI)=7.84(1.03-59.58), P0.047 More... | Association was obse...... Association was observed in both BPI group and any bipolar disorder group. More... | Positive |
| McHugh, P. C.,2009 | rs2421095 - rs1876487 | C-A, A-A C-A, A-A | SPR | X<sup>2</su...... X<sup>2</sup> test:for Bipolar I disorder, OR(95%CI)=0.54(0.21-1.44), P>0.05; for any bipolar disorder, OR(95%CI)=0.76(0.44-1.32), P>0.05; for any mood disorder, OR(95%CI)=1.06(0.70-1.61), P>0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| McHugh, P. C.,2009 | rs2421095 - rs1876487 | C-A, A-G C-A, A-G | SPR | X<sup>2</su...... X<sup>2</sup> test:for Bipolar I disorder, OR(95%CI)=1.81(0.81-4.03), P>0.05; for any bipolar disorder, OR(95%CI)=1.42(0.82-2.44), P>0.05; for any mood disorder, OR(95%CI)=0.59(0.38-0.92), P0.019 More... | No significant asso...... No significant association was found . More... | Negative |
| McHugh, P. C.,2009 | rs2421095 - rs1876487 | C-A, C-A C-A, C-A | SPR | X<sup>2</su...... X<sup>2</sup> test:for Bipolar I disorder, OR(95%CI)=0.69(0.34-1.43), P>0.05; for any bipolar disorder, OR(95%CI)=0.70(0.44-1.10), P>0.05; for any mood disorder, OR(95%CI)=1.17(0.81-1.67), P>0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs234 - rs41261 | A-A A-A | CDHR3 | Haplotypic associati...... Haplotypic association:Z-score=2.688, FBAT P-value = 0.007 More... | Significant associat...... Significant association was found. More... | Positive |
| Emily, M.,2009 | rs2237091 - rs1798011 | PDGFRB KITLG | SNP-SNP interaction ...... SNP-SNP interaction analysis:allelic X<sup>2</sup> test:Marginal effect 1, Pval=0.86, RR=1.01; Marginal effect 2, Pval=0.69, RR=1.02; Interaction test, P-value = 1.13E-09 More... | Significant associat...... Significant association was found. More... | Positive | |
| Palo, O. M.,2010 | rs2169325 - rs1128957 | C-A C-A | TUSC1 | Haplotypic associati...... Haplotypic association:Z-score=-1.505, FBAT P-value = 0.132 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs214468 - rs37742 | A-A A-A | IMMP2L | Haplotypic associati...... Haplotypic association:Z-score=0.639, FBAT P-value = 0.523 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs214459 - rs214468 | A-G A-G | IMMP2L | Haplotypic associati...... Haplotypic association:Z-score=1.304, FBAT P-value = 0.192 More... | No significant asso...... No significant association was found . More... | Negative |
| Shi, J., 2008 (d) | rs2137947 - rs6850524 - rs1534891 | DEC1 CLOCK CSNK1E | FDR-cutoff P-value =...... FDR-cutoff P-value = 1.77E 06; FITF P-value = 7.59E 05 More... | Negative | ||
| Palo, O. M.,2010 | rs2076902 - rs748530 | G-G G-G | ADAMTSL1, SLC24A2 | Haplotypic associati...... Haplotypic association:Z-score=0.343, FBAT P-value = 0.731 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs2040587 - rs2056865 | A-G A-G | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=-2.183, FBAT P-value = 0.029 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs2026349 - rs1414944 | A-G A-G | PIP5K1B | Haplotypic associati...... Haplotypic association:Z-score=-0.844, FBAT P-value = 0.398 More... | No significant asso...... No significant association was found . More... | Negative |
| Nissen, S.,2012 | rs2009667 - rs3484 - rs736720 | A-G-G A-G-G | IFT27, PVALB | Case control replica...... Case control replication:chi square = 22.97,global P-value = 0.000343;chi square = 10.76,individual P-value = 0.00105 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Nissen, S.,2012 | rs2009667 - rs3484 - rs736720 | G-A-G G-A-G | IFT27, PVALB | Case control replica...... Case control replication:chi square = 22.97,global P-value = 0.000343;chi square = 9.81,individual P-value = 0.00174 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Xiang, B., 2013 | rs1928038 - rs1475196 - rs9562689 - rs9567747 - rs1328684 - rs1328684 | C-A-G-A-G-G C-A-G-A-G-G | HTR2A | P-value=0.29, X<s...... P-value=0.29, X<sup>2</sup>=1.16 More... | This haplotype is no...... This haplotype is not significantly associated with BP. More... | Negative |
| Xiang, B., 2013 | rs1928038 - rs1475196 - rs9562689 - rs9567747 - rs1328684 - rs1328684 | C-A-A-G-A-A C-A-A-G-A-A | HTR2A | P-value=0.03, X<s...... P-value=0.03, X<sup>2</sup>=5.08 More... | We found that haplot...... We found that haplotypes with multiple-markers (SNPs rs1928038-rs1475196-rs9562689-rs9567747-rs1328684-rs1328684) showed significant association with BPD-I, with a global P value of 0.003, and three specific haplotypes (CAAGAA, GAGGAA, and CCGAAA) with corrected P values of <0.05. More... | Positive |
| Xiang, B., 2013 | rs1928038 - rs1475196 - rs9562689 - rs9567747 - rs1328684 - rs1328684 | G-A-G-G-A-A G-A-G-G-A-A | HTR2A | P-value=0.02, X<s...... P-value=0.02, X<sup>2</sup>=5.74 More... | We found that haplot...... We found that haplotypes with multiple-markers (SNPs rs1928038-rs1475196-rs9562689-rs9567747-rs1328684-rs1328684) showed significant association with BPD-I, with a global P value of 0.003, and three specific haplotypes (CAAGAA, GAGGAA, and CCGAAA) with corrected P values of <0.05. More... | Positive |
| Xiang, B., 2013 | rs1928038 - rs1475196 - rs9562689 - rs9567747 - rs1328684 - rs1328684 | C-C-G-A-A-A C-C-G-A-A-A | HTR2A | P-value=0.03, X<s...... P-value=0.03, X<sup>2</sup>=4.71 More... | We found that haplot...... We found that haplotypes with multiple-markers (SNPs rs1928038-rs1475196-rs9562689-rs9567747-rs1328684-rs1328684) showed significant association with BPD-I, with a global P value of 0.003, and three specific haplotypes (CAAGAA, GAGGAA, and CCGAAA) with corrected P values of <0.05. More... | Positive |
| Xiang, B., 2013 | rs1928038 - rs1475196 - rs9562689 - rs9567747 - rs1328684 - rs1328684 | C-A-G-A-A-A C-A-G-A-A-A | HTR2A | P-value=0.10, X<s...... P-value=0.10, X<sup>2</sup>=2.69 More... | This haplotype is no...... This haplotype is not significantly associated with BP. More... | Negative |
| Palo, O. M.,2010 | rs1896887 - rs38831 | G-C G-C | CFTR | Haplotypic associati...... Haplotypic association:Z-score=1.295, FBAT P-value = 0.195 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1889915 - rs1074670 | G-G G-G | TRPM3 | Haplotypic associati...... Haplotypic association:Z-score=1.73, FBAT P-value = 0.083 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1880180 - rs1121030 | A-G A-G | SLC13A1 | Haplotypic associati...... Haplotypic association:Z-score=0.592, FBAT P-value = 0.554 More... | No significant asso...... No significant association was found . More... | Negative |
| Gonzalez, R., 2015 | rs1868049 - rs3789327 - rs11022778 | G-A-A G-A-A | ARNTL | P-value=2.99E-03 P-value=2.99E-03 | The global ARNTL hap...... The global ARNTL haploblock permutation test was significantly associated with BD. More... | Positive |
| Palo, O. M.,2010 | rs1858929 - rs2028030 | G-G G-G | SLC26A4 | Haplotypic associati...... Haplotypic association:Z-score=0.504, FBAT P-value = 0.614 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1833083 - rs996867 | A-A A-A | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=0.608, FBAT P-value = 0.542 More... | No significant asso...... No significant association was found . More... | Negative |
| McGrath, C. L.,2009 | rs17684881 - rs17612218 - rs11144020 - rs17612778 - rs17612874 - rs17691363 - rs10869430 | RORB | haplotype(C-G-C-C-C-...... haplotype(C-G-C-C-C-A-G):P-value = 5.08E-05, Permuted P-value < 0.001 More... | Association was obse...... Association was observed only in the case-control sample. More... | Positive | |
| Houlihan, L.M.,2009 | rs17408391 - rs10939038 | PI4K2B | haplotype analysis:g...... haplotype analysis:global P-value > 0.005 in the bipolar disorder sample More... | No statistically sig...... No statistically significant association was found in the bipolar disorder sample. More... | Negative | |
| Shi, J., 2008 (b) | rs1568447 - rs690533 - rs516035 | GGA GGA | GRIN2C | Gene-wide significan...... Gene-wide significant haplotypic association with bipolar disorder: TDT P-value = 0.0110, Gene-wide P-value = 0.0410 More... | Gene-wide significan...... Gene-wide significant haplotypic associations with BP, none of these associations survived correction for multiple testing More... | Positive |
| Palo, O. M.,2010 | rs1555454 - rs9103 | A-G A-G | TEK, C9orf72 | Haplotypic associati...... Haplotypic association:Z-score=0.434, FBAT P-value = 0.664 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1510504 - rs846427 | A-C A-C | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=-1.224, FBAT P-value = 0.221 More... | No significant asso...... No significant association was found . More... | Negative |
| Soler, J., 2016 | rs1507754 - rs10917670 - rs951436 - rs951439 - rs2661319 | T-T-G-G-A T-T-G-G-A | RGS4 | P(unadj)-value=0.030...... P(unadj)-value=0.030, OR(CI95%) = 0.33 (0.12–0.98) More... | The haplotype TTGGA ...... The haplotype TTGGA of RGS4 was found to be under-transmitted to patients. However, this result did not remain significant after multiple test correction. More... | |
| Palo, O. M.,2010 | rs1476878 - rs257376 | G-A G-A | PRKAR2B | Haplotypic associati...... Haplotypic association:Z-score=2.409, FBAT P-value = 0.016 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs1476517 - rs7817 | G-G G-G | DOCK4 IFRD1 | Haplotypic associati...... Haplotypic association:Z-score=1.419, FBAT P-value = 0.155 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1475656 - rs1412340 | A-A A-A | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-2.063, FBAT P-value = 0.039 More... | Significant associat...... Significant association was found. More... | Positive |
| Zandi, P. P., 2007 | rs1457485 - rs4377991 - rs1870126 - rs765847 | ST3GAL1 | P-value = 0.003 P-value = 0.003 | a four-SNP haplotype...... a four-SNP haplotype in the gene desert (rs1457485-rs4377991-rs1870126-rs765847) was associated at P=0.003 More... | Positive | |
| Palo, O. M.,2010 | rs1414944 - rs1889915 | A-G A-G | PIP5K1B, TRPM3 | Haplotypic associati...... Haplotypic association:Z-score=0.801, FBAT P-value = 0.423 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1414237 - rs1360590 | G-G G-G | CDKN2B-AS1 | Haplotypic associati...... Haplotypic association:Z-score=1.392, FBAT P-value = 0.163 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1412340 - rs288886 | G-A G-A | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=2.404, FBAT P-value = 0.016 More... | Significant associat...... Significant association was found. More... | Positive |
| Kandaswamy R., 2014 | rs1400166 - rs2875257 - rs10510353 - rs11708019 - rs1963265 - rs1508724 - rs9823996 - rs11710946 - rs6769814 | GRM7 | P-value=0.007 P-value=0.007 | The most significant...... The most significant haplotype (HAP_GRM7) associated with BP comprising SNPs rs1400166, rs2875257, rs10510353, rs11708019, rs1963265, rs1508724, rs9823996, rs11710946, and rs6769814 (P=0.007) was less common in cases compared to controls (2.2% and 4.3% in cases and controls, respectively). More... | Positive | |
| Palo, O. M.,2010 | rs1360590 - rs1327063 | A-C A-C | CDKN2B-AS1 | Haplotypic associati...... Haplotypic association:Z-score=-1.709, FBAT P-value = 0.087 More... | No significant asso...... No significant association was found . More... | Negative |
| Khan, R. A., 2016 | rs13396535-rs6717029-rs13410341-rs6755392 | T-C-C-A T-C-C-A | ZEB2 | P(unadj)-value=1.56E...... P(unadj)-value=1.56E−04, P-value=7.79E−04 More... | Two haplotypes, one ...... Two haplotypes, one for block rs10197694-rs6430057-rs10928212-rs1427298-13,389,578 (CTAGT: P=0.007, P corrected=0.036) and one for block rs13396535-rs6717029-rs13410341-rs6755392 (TCCA: P=1.56E−04, P corrected=7.79E−04),were significantly associated with BPD. More... | |
| Palo, O. M.,2010 | rs1332677 - rs2169325 | G-C G-C | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-1.482, FBAT P-value = 0.138 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1327063 - rs702223 | C-C C-C | ELAVL2 | Haplotypic associati...... Haplotypic association:Z-score=-2.184, FBAT P-value = 0.028 More... | Significant associat...... Significant association was found. More... | Positive |
| Nissen, S.,2012 | rs129336 - rs130566 - rs5756339 - rs4821523 | C-C-T-A C-C-T-A | IFT27 | TDT:T = 11.49,U = 39...... TDT:T = 11.49,U = 39.48,chi square = 15.37,P-value = 0.0000885 for Family phase 2 More... | The SNPs showed a si...... The SNPs showed a significant association with BD. More... | Positive |
| Ross, K. A.,2011 | rs12227938 - rs9551988 | PSPC1 | SNP interactions:P-v...... SNP interactions:P-value = 0.38 More... | No significant asso...... No significant association was found . More... | Negative | |
| Ross, K. A.,2011 | rs12227938 - rs4850057 | SNP interactions:P-v...... SNP interactions:P-value = 0.39 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Ross, K. A.,2011 | rs12227938 - rs2122231 | SNP interactions:P-v...... SNP interactions:P-value = 0.9 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Ross, K. A.,2011 | rs12227938 - (SNP A-1797773) | SNP interactions:P-v...... SNP interactions:P-value = 0.38 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Kalsi, G., 2006 | rs1194031 - AY070435_29818-insT - AY070435_307CA1 | AY070435 | global P-value = 0.0...... global P-value = 0.0079 More... | The most significant...... The most significant three-marker haplotype was found when combining data from markers rs1190431, 29818-insT, and 307CA1 (empirical p= 0.0079). More... | Positive | |
| Palo, O. M.,2010 | rs1138374 - rs716933 | G-A G-A | SHB | Haplotypic associati...... Haplotypic association:Z-score=3.23, FBAT P-value = 0.001 More... | Significant associat...... Significant association was found. More... | Positive |
| Palo, O. M.,2010 | rs1128957 - rs757099 | C-A C-A | TUSC1 | Haplotypic associati...... Haplotypic association:Z-score=-1.505, FBAT P-value = 0.132 More... | No significant asso...... No significant association was found . More... | Negative |
| McGrath, C. L.,2009 | rs11144033 - rs3903529 - rs968357 | RORB | haplotype(G-A-T):P-v...... haplotype(G-A-T):P-value = 8.92E-05, Permuted P-value = 0.002 More... | Association was obse...... Association was observed only in the case-control sample. More... | Positive | |
| Houlihan, L.M.,2009 | rs10939038 - rs3756207 | PI4K2B | haplotype analysis:g...... haplotype analysis:global P-value > 0.005 in the bipolar disorder sample More... | No statistically sig...... No statistically significant association was found in the bipolar disorder sample. More... | Negative | |
| Palo, O. M.,2010 | rs1074670 - rs1404195 | G-A G-A | TRPM3 | Haplotypic associati...... Haplotypic association:Z-score=2.147, FBAT P-value = 0.031 More... | Significant associat...... Significant association was found. More... | Positive |
| Khan, R. A., 2016 | rs10197694-rs6430057-rs10928212-rs1427298-13,389,578 | C-T-A-G-T C-T-A-G-T | ZEB2 | P(unadj)-value=0.007...... P(unadj)-value=0.007, P-value=0.036 More... | Two haplotypes, one ...... Two haplotypes, one for block rs10197694-rs6430057-rs10928212-rs1427298-13,389,578 (CTAGT: P=0.007, P corrected=0.036) and one for block rs13396535-rs6717029-rs13410341-rs6755392 (TCCA: P=1.56E−04, P corrected=7.79E−04),were significantly associated with BPD. More... | |
| Palo, O. M.,2010 | rs1018254 - rs1475656 | G-T G-T | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=1.012, FBAT P-value = 0.311 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1013920 - rs719530 | A-A A-A | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=-0.952, FBAT P-value = 0.341 More... | No significant asso...... No significant association was found . More... | Negative |
| Hu, X.,2010 | rs10124883 - rs6004133 | ASTN2 PI4KA | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 6.49E-12 for WTCCC data, P-value = 0.027 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10124883 - rs178069 | ASTN2 SNAP29 | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 5.37E-12 for WTCCC data, P-value = 0.031 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10124883 - rs165730 | ASTN2 PI4KA | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.038 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10124883 - rs165596 | ASTN2 SNAP29 | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.035 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10123629 - rs6004133 | ASTN2 PI4KA | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.026 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10123629 - rs178069 | ASTN2 SNAP29 | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.021 for replication study(Chinese sample). More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Hu, X.,2010 | rs10123629 - rs165730 | ASTN2 PI4KA | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.085 for replication study(Chinese sample). More... | No significant asso...... No significant association was found . More... | Negative | |
| Hu, X.,2010 | rs10123629 - rs165596 | ASTN2 SNAP29 | SNP-SNP interaction:...... SNP-SNP interaction:P-value = 0.132 for replication study(Chinese sample). More... | No significant asso...... No significant association was found . More... | Negative | |
| Cordeiro, Q.,2005 | RGS4_SNP1 - RGS4_SNP4 - RGS4_SNP17 - RGS4_SNP18 | G-G-G-G G-G-G-G | RGS4 | Haplotypic associati...... Haplotypic association:Family-based analysis:TDT:X<sup>2</sup>=7.12, P-value = 0.007 in BD; Linkage disequilibrium analyses:haplotypes G-G-G-G and A-T-A-A for all four SNPs accounted for over 81% of all estimated haplotypes among the controls. Two-point LD analysis showed that D'-values exceeded 0.85 for all combinations of SNPs among the cases and controls. More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Abou Jamra, R.,2005(a) | PRODH2026 - PRODH1945 - PRODH1482 | PRODH | Haplotypic associati...... Haplotypic association:Global P-value = 0.903(based on 100, 000 replications) for BPAD. More... | No significant asso...... No significant association was found . More... | Negative | |
| Abou Jamra, R.,2005(a) | PRODH2026 - PRODH1945 | PRODH | Haplotypic associati...... Haplotypic association:Global P-value = 0.755(based on 100, 000 replications) for BPAD. More... | No significant asso...... No significant association was found . More... | Negative | |
| Abou Jamra, R.,2005(a) | PRODH1945 - PRODH1482 | PRODH | Haplotypic associati...... Haplotypic association:Global P-value = 0.804(based on 100, 000 replications) for BPAD. More... | No significant asso...... No significant association was found . More... | Negative | |
| Borsotto, M., 2007 | PPP2R2C_Intron5_24-257/320 - PPP2R2C_Intron5_99-24175/218 | (24-257/320)-(99-241...... (24-257/320)-(99-24175/218) More... | PPP2R2C | the risk haplotype f...... the risk haplotype for 24-257/320 and 99-24175/218 is 'AA' in the Labimo collection, no P-value given in the original text More... | an individual carryi...... an individual carrying the haplotype 'AA' at biallelic markers 24-257/320 and 99-24175/218 presents an increased risk of developing BD. More... | Positive |
| Borsotto, M., 2007 | PPP2R2C_Intron1d_99-24169/139 - PPP2R2C_Intron4_24-247/216 | (99-24169/139)-(24-2...... (99-24169/139)-(24-247/216) More... | PPP2R2C | the risk haplotype f...... the risk haplotype for 99-24169/139 and 24-247/216 is 'AG' in the UCL collection, no P-value given in the original text More... | an individual carryi...... an individual carrying the haplotype 'AG' at biallelic markers 99-24169/139 and 24-247/216 presents an increased risk of developing BD. More... | Positive |
| Goes, F. S., 2009 | NRG241930 - NRG2243177 - rs7819063 | G-T-T G-T-T | NRG1 | Haplotype Associatio...... Haplotype Association:FBAT:individual P-value = 0.0174(Standard BP), 0.0007(Psychotic BP), 0.163(Mood-incongruent psychotic BP); global P-value = 0.0182(Standard BP), 0.0016(Psychotic BP), 0.0983(Mood-incongruent psychotic BP) More... | Association was obse...... Association was observed in both standard BP and Psychotic BP. More... | Positive |
| Goes, F. S., 2009 | NRG2243177 - rs7819063 | T-T T-T | NRG1 | Haplotype Associatio...... Haplotype Association:FBAT:individual P-value = 0.0126(Standard BP), 0.0004(Psychotic BP), 0.1508(Mood-incongruent psychotic BP); global P-value = 0.0462(Standard BP), 0.0039(Psychotic BP), 0.5529(Mood-incongruent psychotic BP) More... | Association was obse...... Association was observed in both standard BP and Psychotic BP. More... | Positive |
| Cassidy, F., 2006 | NRG1_SNP8NRG243177 - NRG1_478B14-848 | 1-2 1-2 | NRG1 | TDT P-value = 0.17, ...... TDT P-value = 0.17, X<sup>2</sup>=1.9, global P-value = 0.78, global X<sup>2</sup>=4.76, df=8 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Negative |
| Cassidy, F., 2006 | NRG1_SNP8NRG221533 - NRG1_SNP8NRG243177 - NRG1_478B14-848 - NRG1_420M9-1395 | 1-1-2-3 1-1-2-3 | NRG1 | TDT P-value = 0.1, X...... TDT P-value = 0.1, X<sup>2</sup>=2.71, global P-value = 0.48, global X<sup>2</sup>=5.52, df=6 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD. A haplotype comprised of alleles from the three microsatellite markers (M3-M4-M5) did exhibit a marginal association which was not significant at the global haplotype level. More... | Negative |
| Cassidy, F., 2006 | NRG1_SNP8NRG221533 - NRG1_SNP8NRG243177 | 2-2 2-2 | NRG1 | TDT P-value = 0.91, ...... TDT P-value = 0.91, X<sup>2</sup>=0.01, global P-value = 0.89, global X<sup>2</sup>=0.23, df=2 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Negative |
| Cassidy, F., 2006 | NRG1_SNP8NRG221533 - NRG1_478B14-848 - NRG1_420M9-1395 | 2-2-3 2-2-3 | NRG1 | TDT P-value = 0.79, ...... TDT P-value = 0.79, X<sup>2</sup>=0.07, global P-value = 0.49, global X<sup>2</sup>=5.44, df=6 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Negative |
| Cassidy, F., 2006 | NRG1_478B14-848 - NRG1_420M9-1395 - NRG1_D8S1810 | 1-3-5 1-3-5 | NRG1 | TDT P-value = 0.04, ...... TDT P-value = 0.04, X<sup>2</sup>=4.23, global P-value = 0.31, global X<sup>2</sup>=7.15, df=6 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Positive |
| Cassidy, F., 2006 | NRG1_478B14-848 - NRG1_420M9-1395 | 1-3 1-3 | NRG1 | TDT P-value = 0.14, ...... TDT P-value = 0.14, X<sup>2</sup>=2.13, global P-value = 0.53, global X<sup>2</sup>=5.07, df=6 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Negative |
| Cassidy, F., 2006 | NRG1_420M9-1395 - NRG1_D8S1810 | 3-6 3-6 | NRG1 | TDT P-value = 0.9, X...... TDT P-value = 0.9, X<sup>2</sup>=0.01, global P-value = 0.69, global X<sup>2</sup>=3.91, df=6 More... | A range of two to th...... A range of two to three marker haplotypes, including HAPICE and HapBIRE, also failed to exhibit any evidence of association with BPAD More... | Negative |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | c-a-g c-a-g | NOS3 | P-value = 0.15, perm...... P-value = 0.15, permutation-based P-value = 0.515, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). More... | Negative |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | c-a-t c-a-t | NOS3 | P-value = 0.003, per...... P-value = 0.003, permutation-based P-value = 0.212, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). More... | Positive |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | c-b-g c-b-g | NOS3 | P-value = 0.006, per...... P-value = 0.006, permutation-based P-value = 0.022, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). The estimated c-b-g and t-a-g haplotypes were under-represented in BD patients (p=0.022, and p<0.001 respectively). More... | Positive |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | c-b-t c-b-t | NOS3 | P-value = 0.197, per...... P-value = 0.197, permutation-based P-value = 0.408, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). More... | Negative |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | t-a-g t-a-g | NOS3 | P-value = 0, permuta...... P-value = 0, permutation-based P-value < 0.001, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). The estimated c-b-g and t-a-g haplotypes were under-represented in BD patients (p=0.022, and p<0.001 respectively). After correction for multiple testing, the frequencies differed significantly only for the estimated t-a-g haplotype. More... | Positive |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | t-b-g t-b-g | NOS3 | P-value = 0.563, per...... P-value = 0.563, permutation-based P-value = 0.052, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). Furthermore, the estimated t-b-g haplotype had a tendency to be over-represented in BD patients (p=0.052). More... | Negative |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | t-b-t t-b-t | NOS3 | P-value = 0.08, perm...... P-value = 0.08, permutation-based P-value = 0.601, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). More... | Negative |
| Reif, A., 2006 (b) | NOS3_T-786C - NOS3_Intron4_VNTR - NOS3_G894T | c-c-t c-c-t | NOS3 | P-value = 0, permuta...... P-value = 0, permutation-based P-value = 0.523, global P-value = 0.021 More... | A significant global...... A significant global haplotype association with BD was observed (p=0.02). More... | Negative |
| Washizuka, S., 2004 | NDUFV2_-796C>G - NDUFV2_-602G>A - NDUFV2_-233T>C | NDUFV2 | global P-value = 0.0...... global P-value = 0.01 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-796C>G - NDUFV2_-602G>A | NDUFV2 | global P-value = 0.0...... global P-value = 0.002 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-602G>A - NDUFV2_-233T>CNDUFV2_86C>T | NDUFV2 | global P-value = 0.0...... global P-value = 0.001 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-602G>A - NDUFV2_-233T>C | NDUFV2 | global P-value = 0.0...... global P-value = 0.01 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-602G>A | A-A A-A | NDUFV2 | global P-value < ...... global P-value < 0.0001, individual P-value = 0.55, X<sup>2</sup>=0.34 in Japanese; global P-value = 0.01, individual P-value = 0.20, X<sup>2</sup>=1.61 in NIMH pedigrees More... | Negative | |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-602G>A | G-A G-A | NDUFV2 | global P-value < ...... global P-value < 0.0001, individual P-value < 0.0001, X<sup>2</sup>=20.35 in Japanese; global P-value = 0.01, individual P-value = 0.04, X<sup>2</sup>=4.18 in NIMH pedigrees More... | Distributions of hap...... Distributions of haplotype frequencies differed significantly between patients with BD and control subjects. Among the haplotypes, the G-G haplotype was significantly more frequently seen in BD, whereas G-A and A-G haplotypes were significantly less common in patients with BD compared with control subjects. We found significant association of the NDUFV2 haplotypes with BD in NIMH pedigrees. Two haplotypes (G-A and A-G) tended to be undertransmitted in parents-proband trios of NIMH samples. More... | Positive |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-602G>A | A-G A-G | NDUFV2 | global P-value < ...... global P-value < 0.0001, individual P-value < 0.0001, X<sup>2</sup>=23.81 in Japanese; global P-value = 0.01, individual P-value = 0.01, X<sup>2</sup>=5.59 in NIMH pedigrees More... | Distributions of hap...... Distributions of haplotype frequencies differed significantly between patients with BD and control subjects. Among the haplotypes, the G-G haplotype was significantly more frequently seen in BD, whereas G-A and A-G haplotypes were significantly less common in patients with BD compared with control subjects. We found significant association of the NDUFV2 haplotypes with BD in NIMH pedigrees. Two haplotypes (G-A and A-G) tended to be undertransmitted in parents-proband trios of NIMH samples. More... | Positive |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-602G>A | G-G G-G | NDUFV2 | global P-value = 0.0...... global P-value = 0.001, individual P-value < 0.0001, X<sup>2</sup>=10.79 in Japanese; global P-value = 0.01, individual P-value = 0.76, X<sup>2</sup>=0.08 in NIMH pedigrees More... | Distributions of hap...... Distributions of haplotype frequencies differed significantly between patients with BD and control subjects. Among the haplotypes, the G-G haplotype was significantly more frequently seen in BD, whereas G-A and A-G haplotypes were significantly less common in patients with BD compared with control subjects. More... | Positive |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-3245T>C - NDUFV2_-3041T>G | NDUFV2 | global P-value < ...... global P-value < 0.001 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-3542G>A - NDUFV2_-3245T>C | NDUFV2 | global P-value < ...... global P-value < 0.001 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-3245T>C - NDUFV2_-3041T>G - NDUFV2_-2694A>G | NDUFV2 | global P-value = 0.2...... global P-value = 0.28 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-3245T>C - NDUFV2_-3041T>G | NDUFV2 | global P-value = 0.0...... global P-value = 0.09 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-3041T>G - NDUFV2_-2694A>G - NDUFV2_-1020G>T | NDUFV2 | global P-value = 0.3...... global P-value = 0.30 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-3041T>G - NDUFV2_-2694A>G | NDUFV2 | global P-value = 0.0...... global P-value = 0.08 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-2694A>G - NDUFV2_-1020G>T - NDUFV2_-796C>G | NDUFV2 | global P-value = 0.1...... global P-value = 0.14 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-2694A>G - NDUFV2_-1020G>T | NDUFV2 | global P-value = 0.2...... global P-value = 0.25 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-233T>C - NDUFV2_86C>T | NDUFV2 | global P-value = 0.7...... global P-value = 0.70 More... | Negative | ||
| Washizuka, S., 2004 | NDUFV2_-1020G>T - NDUFV2_-796C>G - NDUFV2_-602G>A | NDUFV2 | global P-value = 0.0...... global P-value = 0.009 More... | This analysis showed...... This analysis showed evidence of association with BD in two limited regions around -3542G>A and -602G>A. More... | Positive | |
| Washizuka, S., 2004 | NDUFV2_-1020G>T - NDUFV2_-796C>G | NDUFV2 | global P-value = 0.6...... global P-value = 0.64 More... | Negative | ||
| Kazuno, A. A.,2009 | mtDNA_haplogroup_N9a | mtDNA | logistic regression ...... logistic regression analysis:P<0.05 using haplogroup D4 as a reference More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Schumacher, J.,2004 | MDAAO4 - MDAAO5 - MDAAO6 | A-C-G A-C-G | DAO | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.325, individual P-value = 0.032, OR=1.29 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Schumacher, J.,2004 | MDAAO4 - MDAAO5 - MDAAO6 | A-C-T A-C-T | DAO | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.325, individual P-value = 0.459, OR=0.91 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Schumacher, J.,2004 | MDAAO4 - MDAAO5 - MDAAO6 | C-C-G C-C-G | DAO | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.325, individual P-value = 0.471, OR=0.82 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Schumacher, J.,2004 | MDAAO4 - MDAAO5 - MDAAO6 | C-T-T C-T-T | DAO | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.325, individual P-value = 0.213, OR=0.85 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | T-4 T-4 | MAOA | TDT P-value = 0.012,...... TDT P-value = 0.012, X<sup>2</sup>=6.32 More... | By the haplotype TDT...... By the haplotype TDT analysis, the T-4 haplotype was found significantly associated with bipolar disorder More... | Positive |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | G-3 G-3 | MAOA | TDT P-value = 0.117,...... TDT P-value = 0.117, X<sup>2</sup>=2.46 More... | Negative | |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | T-3 T-3 | MAOA | TDT P-value = 0.756,...... TDT P-value = 0.756, X<sup>2</sup>=0.1 More... | Negative | |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | G-4 G-4 | MAOA | TDT P-value = 0.004,...... TDT P-value = 0.004, X<sup>2</sup>=8.14 More... | Negative | |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | T-5 T-5 | MAOA | TDT P-value = 0.239,...... TDT P-value = 0.239, X<sup>2</sup>=1.39 More... | Negative | |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | T-3.5 T-3.5 | MAOA | TDT P-value = 1, X&l...... TDT P-value = 1, X<sup>2</sup>=0 More... | Negative | |
| Muller, D. J., 2007 | MAOA_-941T>G - MAOA_-VNTR | G-5 G-5 | MAOA | TDT P-value = 0.24, ...... TDT P-value = 0.24, X<sup>2</sup>=1.39 More... | Negative | |
| Schumacher, J.,2004 | M12 - M15 - M23 - M24 | T-A-C-T T-A-C-T | DAOA | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.08, individual P-value = 0.497, OR=1.16 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Schumacher, J.,2004 | M12 - M15 - M23 - M24 | T-A-T-A T-A-T-A | DAOA | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.08, individual P-value = 0.815, OR=1.04 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Schumacher, J.,2004 | M12 - M15 - M23 - M24 | C-G-C-T C-G-C-T | DAOA | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.08, individual P-value = 0.069, OR=1.29 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Schumacher, J.,2004 | M12 - M15 - M23 - M24 | C-G-T-A C-G-T-A | DAOA | Haplotype analysis:a...... Haplotype analysis:allele, global P-value = 0.08, individual P-value = 0.032, OR=0.73 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Sjoholt, G., 2004 | IMPA2_382 - 44G>A - IMPA2_443G>A (R148Q) - IMPA2_490+13_14insA | G-G-0 G-G-0 | IMPA2 | Individual haplotype...... Individual haplotype P-value (1 d.f.)=0.71, Global haplotypes P-value (d.f.)=0.89 (3) More... | Negative | |
| Sjoholt, G., 2004 | IMPA2_230+141G>A - IMPA2_382 - 44G>A - IMPA2_443G>A (R148Q) | G-G-G G-G-G | IMPA2 | Individual haplotype...... Individual haplotype P-value (1 d.f.)=0.62, Global haplotypes P-value (d.f.)=0.87 (4) More... | Negative | |
| Sjoholt, G., 2004 | IMPA2_159T>C - IMPA2_230+141G>A - IMPA2_382 - 44G>A | T-G-G T-G-G | IMPA2 | Individual haplotype...... Individual haplotype P-value (1 d.f.)=0.10, Global haplotypes P-value (d.f.)=0.58 (5) More... | Negative | |
| Sjoholt, G., 2004 | IMPA2_-97-15G>A - IMPA2_159T>C - IMPA2_230+141G>A | G-T-G G-T-G | IMPA2 | Individual haplotype...... Individual haplotype P-value (1 d.f.)=0.15, Global haplotypes P-value (d.f.)=0.36 (3) More... | Negative | |
| Ohnishi, T., 2007 | IMPA2_-708G>A - rs2075824 - IMPA2_-207T>C | IMPA2 | P-value = 0.015 P-value = 0.015 | obtained a significa...... obtained a significant empirical p-value for the three-locus window More... | Positive | |
| Ohnishi, T., 2007 | IMPA2_-708G>A - rs2075824 | IMPA2 | P-value = 0.017 P-value = 0.017 | displayed evidence o...... displayed evidence of association with bipolar illness More... | Positive | |
| Sjoholt, G., 2004 | IMPA2_-461C>T - IMPA2_-241_-237dup - IMPA2_-207T>C - IMPA2_-185A>G | C-0-T C-0-T | IMPA2 | Individual haplotype...... Individual haplotype P-value (1 d.f.)=0.002, Global haplotypes P-value (d.f.)=0.03 (5) More... | demonstrating that c...... demonstrating that certain combinations of the DNA variants in the promoter and 5'- end were significantly more often transmitted to the affected offspring than expected. More... | Positive |
| Sjoholt, G., 2004 | IMPA2_-461C>T - IMPA2_-241_-237dup - IMPA2_-207T>C - IMPA2_-185A>G | 0-T-A 0-T-A | IMPA2 | Individual haplotype...... Individual haplotype P-value (1 d.f.)=0.02, Global haplotypes P-value (d.f.)=0.02 (6) More... | demonstrating that c...... demonstrating that certain combinations of the DNA variants in the promoter and 5'- end were significantly more often transmitted to the affected offspring than expected. More... | Positive |
| Sjoholt, G., 2004 | IMPA2_-461C>T - IMPA2_-241_-237dup - IMPA2_-207T>C - IMPA2_-185A>G | C-0-T-A C-0-T-A | IMPA2 | P-value(1 d.f.)=0.05...... P-value(1 d.f.)=0.05, X<sup>2</sup>=3.7399 in Palestinian Arab trios More... | The most frequent ha...... The most frequent haplotype, [-461C; -241_-237dup negative; -207T; -185A] was transmitted significantly more often than expected to the bipolar offspring. More... | Negative |
| Sjoholt, G., 2004 | IMPA2_-461C>T - IMPA2_-241_-237dup - IMPA2_-207T>C - IMPA2_-185A>G | C-0-T-G C-0-T-G | IMPA2 | P-value(1 d.f.)=0.15...... P-value(1 d.f.)=0.15, X<sup>2</sup>=2.0825 in Palestinian Arab trios More... | Negative | |
| Sjoholt, G., 2004 | IMPA2_-461C>T - IMPA2_-241_-237dup - IMPA2_-207T>C - IMPA2_-185A>G | T-0-C-G T-0-C-G | IMPA2 | P-value(1 d.f.)=0.04...... P-value(1 d.f.)=0.04, X<sup>2</sup>=4.0653 in Palestinian Arab trios More... | The second most freq...... The second most frequent haplotype, [-461T; -241_-237dup-negative; -207C; -185G] was transmitted significantly less often than expected to the cases. More... | Positive |
| Sjoholt, G., 2004 | IMPA2_-461C>T - IMPA2_-241_-237dup - IMPA2_-207T>C - IMPA2_-185A>G | T-D-C-G T-D-C-G | IMPA2 | P-value(1 d.f.)=0.26...... P-value(1 d.f.)=0.26, X<sup>2</sup>=1.2783 in Palestinian Arab trios More... | Negative | |
| Sjoholt, G., 2004 | IMPA2_-207T>C - IMPA2_-185A>G - IMPA2_-97 - 15G>A | T-A-G T-A-G | IMPA2 | Individual haplotype...... Individual haplotype P-value (1 d.f.)=0.02, Global haplotypes P-value (d.f.)=0.21 (7) More... | demonstrating that c...... demonstrating that certain combinations of the DNA variants in the promoter and 5'- end were significantly more often transmitted to the affected offspring than expected. More... | Positive |
| Sjoholt, G., 2004 | IMPA2_-185A>G - IMPA2_-97 - 15G>A - IMPA2_159T>C | A-G-T A-G-T | IMPA2 | Individual haplotype...... Individual haplotype P-value (1 d.f.)=0.03, Global haplotypes P-value (d.f.)=0.26 (6) More... | demonstrating that c...... demonstrating that certain combinations of the DNA variants in the promoter and 5'- end were significantly more often transmitted to the affected offspring than expected. More... | Positive |
| Pereira, A. C.,2011 | IGF1_(CA)n - rs2195243 - rs12309723 | 306-G-A 306-G-A | IGF1 | Haplotype analysis:l...... Haplotype analysis:likelihood ratio test:global empirical P-value = 0.00068 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Rezaei, Z.,2012 | GSTZ1_ - 1002A - GSTZ1_32Glu - GSTZ1_42Gly | G-Glu-Gly G-Glu-Gly | GSTZ1 | X<sup>2</s...... X<sup>2</sup>= 5.744, d.f. = 1, P-value = 0.016. More... | Our present findings...... Our present findings supported the association between polymorphisms of GSTZ1 and susceptibility to early-onset of BPD. More... | Positive |
| Lee, Y. J.,2011 | GSK3beta_promoter_1727A/T - GSK3beta_promoter_50C/T | GSK3B | Haplotype trend regr...... Haplotype trend regression P-value = 0.686 More... | No significant asso...... No significant association was found . More... | Negative | |
| Lee, K. Y., 2006 (b) | GSK-3 beta_-1727A/T - GSK-3 beta_-50C/T | A-C, A-T, T-C, T-T A-C, A-T, T-C, T-T | GSK3B | P-value = 0.68 for B...... P-value = 0.68 for BD, P-value = 0.54 for BD and SZ More... | There was no differe...... There was no difference in the haplotype frequency combination between the patient and control groups. More... | Negative |
| Barrett, T. B., 2007 | GRK3_SNP5 - GRK3_SNP6 - GRK3_2992_SNP14 - GRK3_SNP15 - GRK3_15401_SNP28 | 1-1-1-1-2 1-1-1-1-2 | ADRBK2 | TDT P-value = 0.0127...... TDT P-value = 0.0127, X<sup>2</sup>=6.21, OR=3.6; Local overall empirical P-value = 0.003 for 5 markers More... | Haplotype A is notab...... Haplotype A is notably overtransmitted. More... | Positive |
| Barrett, T. B., 2007 | GRK3_SNP5 - GRK3_SNP6 - GRK3_2992_SNP14 - GRK3_SNP15 - GRK3_15401_SNP28 | 1-2-1-1-1 1-2-1-1-1 | ADRBK2 | TDT P-value = 0.02, ...... TDT P-value = 0.02, X<sup>2</sup>=5.41, OR=0.47; Local overall empirical P-value = 0.003 for 5 markers More... | overall empirical P-...... overall empirical P-value for 5 markers resulted in stronger evidence of association More... | Positive |
| Barrett, T. B., 2007 | GRK3_SNP5 - GRK3_SNP6 - GRK3_2992_SNP14 - GRK3_SNP15 - GRK3_15401_SNP28 | 1-1-2-1-1 1-1-2-1-1 | ADRBK2 | TDT P-value = 0.7252...... TDT P-value = 0.7252, X<sup>2</sup>=0.12, OR=0.75; Local overall empirical P-value = 0.003 for 5 markers More... | overall empirical P-...... overall empirical P-value for 5 markers resulted in stronger evidence of association More... | Negative |
| Barrett, T. B., 2007 | GRK3_SNP5 - GRK3_SNP6 - GRK3_2992_SNP14 - GRK3_SNP15 - GRK3_15401_SNP28 | 1-2-2-1-1 1-2-2-1-1 | ADRBK2 | TDT P-value = 0.0009...... TDT P-value = 0.0009, X<sup>2</sup>=11.06, OR=2.5; Local overall empirical P-value = 0.003 for 5 markers More... | The F/G haplotype sh...... The F/G haplotype shows the strongest evidence for association with disease of all haplotypes tested. More... | Positive |
| Barrett, T. B., 2007 | GRK3_SNP5 - GRK3_SNP6 - GRK3_2992_SNP14 - GRK3_SNP15 - GRK3_15401_SNP28 | 1-1-2-2-1 1-1-2-2-1 | ADRBK2 | TDT P-value = 0.0511...... TDT P-value = 0.0511, X<sup>2</sup>=3.81, OR=2.36; Local overall empirical P-value = 0.003 for 5 markers More... | Haplotype H is notab...... Haplotype H is notably overtransmitted. More... | Negative |
| Barrett, T. B., 2007 | GRK3_SNP5 - GRK3_SNP6 - GRK3_2992_SNP14 - GRK3_SNP15 - GRK3_15401_SNP28 | 1-2-2-2-1 1-2-2-2-1 | ADRBK2 | TDT P-value = 0.6751...... TDT P-value = 0.6751, X<sup>2</sup>=0.18, OR=1.08; Local overall empirical P-value = 0.003 for 5 markers More... | overall empirical P-...... overall empirical P-value for 5 markers resulted in stronger evidence of association More... | Negative |
| Barrett, T. B., 2007 | GRK3_SNP5 - GRK3_SNP6 - GRK3_2992_SNP14 - GRK3_SNP15 - GRK3_15401_SNP28 | 2-2-2-2-1 2-2-2-2-1 | ADRBK2 | TDT P-value = 0.2441...... TDT P-value = 0.2441, X<sup>2</sup>=1.36, OR=0.82; Local overall empirical P-value = 0.003 for 5 markers More... | overall empirical P-...... overall empirical P-value for 5 markers resulted in stronger evidence of association More... | Negative |
| Barrett, T. B., 2007 | GRK3_SNP5 - GRK3_SNP6 - GRK3_2992_SNP14 - GRK3_SNP15 - GRK3_15401_SNP28 | 2-2-2-1-1 2-2-2-1-1 | ADRBK2 | TDT P-value = 0.2726...... TDT P-value = 0.2726, X<sup>2</sup>=1.2, OR=0.5; Local overall empirical P-value = 0.003 for 5 markers More... | overall empirical P-...... overall empirical P-value for 5 markers resulted in stronger evidence of association More... | Negative |
| Barrett, T. B., 2007 | GRK3_SNP5 - GRK3_SNP6 - GRK3_2992_SNP14 - GRK3_SNP15 - GRK3_15401_SNP28 | 2-1-1-1-1 2-1-1-1-1 | ADRBK2 | TDT P-value = 0.3549...... TDT P-value = 0.3549, X<sup>2</sup>=0.86, OR=0.9; Local overall empirical P-value = 0.003 for 5 markers More... | overall empirical P-...... overall empirical P-value for 5 markers resulted in stronger evidence of association More... | Negative |
| Barrett, T. B., 2007 | GRK3_SNP5 - GRK3_SNP6 - GRK3_2992_SNP14 - GRK3_SNP15 - GRK3_15401_SNP28 | 1-1-1-1-1 1-1-1-1-1 | ADRBK2 | TDT P-value = 0.5991...... TDT P-value = 0.5991, X<sup>2</sup>=0.28, OR=1; Local overall empirical P-value = 0.003 for 5 markers More... | overall empirical P-...... overall empirical P-value for 5 markers resulted in stronger evidence of association More... | Negative |
| Barrett, T. B., 2007 | GRK3_SNP5 - GRK3_SNP6 - GRK3_2992_SNP14 - GRK3_SNP15 | ADRBK2 | Local overall empiri...... Local overall empirical P-value = 0.0119 for 4 markers More... | strong evidence of a...... strong evidence of association was found More... | Positive | |
| Martucci, L., 2006 | GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C | T-C-C T-C-C | GRIN2B | P-value = 0.015899, ...... P-value = 0.015899, Z=2.411 More... | A preferential trans...... A preferential transmission of haplotype T-C-C in the bipolar sample was detected. More... | Positive |
| Martucci, L., 2006 | GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C | T-A-C T-A-C | GRIN2B | P-value = 0.319957, ...... P-value = 0.319957, Z=-0.995 More... | Negative | |
| Martucci, L., 2006 | GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C | G-C-C G-C-C | GRIN2B | P-value = 0.269829, ...... P-value = 0.269829, Z=-1.103 More... | Negative | |
| Martucci, L., 2006 | GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C | G-A-C G-A-C | GRIN2B | P-value = 0.184876, ...... P-value = 0.184876, Z=1.326 More... | Negative | |
| Martucci, L., 2006 | GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C | T-C-T T-C-T | GRIN2B | P-value = 0.081573, ...... P-value = 0.081573, Z=-1.742 More... | Negative | |
| Martucci, L., 2006 | GRIN2B_T200G - GRIN2B_A5806C - GRIN2B_T5988C | G-C-T G-C-T | GRIN2B | P-value = 0.448665, ...... P-value = 0.448665, Z=-0.758 More... | Negative | |
| Degn, B.,2001 | GATA41E12 - D12S2075 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.335, P-value(T4)=0.219 More... | No significant asso...... No significant association was found . More... | Negative | |
| Oswald, P., 2004 | g.196A_ g.11757G | BDNF | P-value = 0.44 by ch...... P-value = 0.44 by chi-square analysis More... | represented >95% ...... represented >95% of four haplotypes present in the population but the global distribution of the four haplotypes was not significantly different between patients and controls More... | Negative | |
| Del Zompo, M., 2007 | DRD1_-800T/C - DRD1_-48A/G - DRD1_1403T/C | -800T/-48A/1403T -800T/-48A/1403T | DRD1 | HHRR P-value = 0.7, ...... HHRR P-value = 0.7, X<sup>2</sup>=0.143 in Toronto Sample; HHRR P-value = 0.23, X<sup>2</sup>=1.414 in Sardinian Sample; HHRR P-value = 0.77, X<sup>2</sup>=0.08 in combined sample; Global P-value = 0.024, X<sup>2</sup>=16.11, df=7 in Toronto Sample; global P-value = 0.00042, X<sup>2</sup>=26.38, df=7 in Sardinian Sample; global P-value = 0.00085, X<sup>2</sup>=24.71, df=7 in combined sample More... | there is a significa...... there is a significant global chi-square in all samples More... | Negative |
| Del Zompo, M., 2007 | DRD1_-800T/C - DRD1_-48A/G - DRD1_1403T/C | -800T/-48A/1403C -800T/-48A/1403C | DRD1 | HHRR P-value = 0.96,...... HHRR P-value = 0.96, X<sup>2</sup>=0.001 in Toronto Sample; HHRR P-value = 0.0009, X<sup>2</sup>=11 in Sardinian Sample; HHRR P-value = 0.02, X<sup>2</sup>=5.19 in combined sample; Global P-value = 0.024, X<sup>2</sup>=16.11, df=7 in Toronto Sample; global P-value = 0.00042, X<sup>2</sup>=26.38, df=7 in Sardinian Sample; global P-value = 0.00085, X<sup>2</sup>=24.71, df=7 in combined sample More... | the haplotype was in...... the haplotype was increasingly represented in Toronto sample and was less frequent in cases than in control in Sardinian sample and there is a significant global chi-square in all samples More... | Positive |
| Del Zompo, M., 2007 | DRD1_-800T/C - DRD1_-48A/G - DRD1_1403T/C | -800T/-48G/1403T -800T/-48G/1403T | DRD1 | HHRR P-value = 0.15,...... HHRR P-value = 0.15, X<sup>2</sup>=2.002 in Toronto Sample; HHRR P-value = 0.007, X<sup>2</sup>=7.208 in Sardinian Sample; HHRR P-value = 0.33, X<sup>2</sup>=0.93 in combined sample; Global P-value = 0.024, X<sup>2</sup>=16.11, df=7 in Toronto Sample; global P-value = 0.00042, X<sup>2</sup>=26.38, df=7 in Sardinian Sample; global P-value = 0.00085, X<sup>2</sup>=24.71, df=7 in combined sample More... | there is a significa...... there is a significant global chi-square in all samples More... | Negative |
| Del Zompo, M., 2007 | DRD1_-800T/C - DRD1_-48A/G - DRD1_1403T/C | -800T/-48G/1403C -800T/-48G/1403C | DRD1 | HHRR P-value = 0.002...... HHRR P-value = 0.002, X<sup>2</sup>=9.219 in Toronto Sample; HHRR P-value = 0.001, X<sup>2</sup>=10.06 in combined sample; Global P-value = 0.024, X<sup>2</sup>=16.11, df=7 in Toronto Sample; global P-value = 0.00042, X<sup>2</sup>=26.38, df=7 in Sardinian Sample; global P-value = 0.00085, X<sup>2</sup>=24.71, df=7 in combined sample More... | there is a significa...... there is a significant global chi-square in all samples More... | Negative |
| Del Zompo, M., 2007 | DRD1_-800T/C - DRD1_-48A/G - DRD1_1403T/C | -800C/-48A/1403T -800C/-48A/1403T | DRD1 | HHRR P-value = 0.43,...... HHRR P-value = 0.43, X<sup>2</sup>0.604 in Toronto Sample; HHRR P-value = 0.41, X<sup>2</sup>=0.66 in combined sample ; Global P-value = 0.024, X<sup>2</sup>=16.11, df=7 in Toronto Sample; global P-value = 0.00042, X<sup>2</sup>=26.38, df=7 in Sardinian Sample; global P-value = 0.00085, X<sup>2</sup>=24.71, df=7 in combined sample More... | there is a significa...... there is a significant global chi-square in all samples More... | Negative |
| Del Zompo, M., 2007 | DRD1_-800T/C - DRD1_-48A/G - DRD1_1403T/C | -800C/-48A/1403C -800C/-48A/1403C | DRD1 | HHRR P-value = 0.01,...... HHRR P-value = 0.01, X<sup>2</sup>=5.679 in Sardinian Sample; HHRR P-value = 0.008, X<sup>2</sup>=6.87 in combined sample; Global P-value = 0.024, X<sup>2</sup>=16.11, df=7 in Toronto Sample; global P-value = 0.00042, X<sup>2</sup>=26.38, df=7 in Sardinian Sample; global P-value = 0.00085, X<sup>2</sup>=24.71, df=7 in combined sample More... | there is a significa...... there is a significant global chi-square in all samples More... | Negative |
| Del Zompo, M., 2007 | DRD1_-800T/C - DRD1_-48A/G - DRD1_1403T/C | -800C/-48G/1403T -800C/-48G/1403T | DRD1 | HHRR P-value = 0.047...... HHRR P-value = 0.047, X<sup>2</sup>=3.947 in Toronto Sample; HHRR P-value = 0.16, X<sup>2</sup>=1.919 in Sardinian Sample; HHRR P-value = 0.01, X<sup>2</sup>=6.54 in combined sample; Global P-value = 0.024, X<sup>2</sup>=16.11, df=7 in Toronto Sample; global P-value = 0.00042, X<sup>2</sup>=26.38, df=7 in Sardinian Sample; global P-value = 0.00085, X<sup>2</sup>=24.71, df=7 in combined sample More... | the haplotype was in...... the haplotype was increasingly represented in Toronto sample and was more frequent in cases than in control subjects in Sardinian sample and was more frequent in BP I than in the control group in combined sample and there is a significant global chi-square in all samples More... | Positive |
| Del Zompo, M., 2007 | DRD1_-800T/C - DRD1_-48A/G - DRD1_1403T/C | -800C/-48G/1403C -800C/-48G/1403C | DRD1 | HHRR P-value = 0.26,...... HHRR P-value = 0.26, X<sup>2</sup>=1.252 in Toronto Sample; HHRR P-value = 0.87, X<sup>2</sup>=0.024 in Sardinian Sample; HHRR P-value = 0.66, X<sup>2</sup>=0.19 in combined sample; Global P-value = 0.024, X<sup>2</sup>=16.11, df=7 in Toronto Sample; global P-value = 0.00042, X<sup>2</sup>=26.38, df=7 in Sardinian Sample; global P-value = 0.00085, X<sup>2</sup>=24.71, df=7 in combined sample More... | there is a significa...... there is a significant global chi-square in all samples More... | Negative |
| Greenwood, T. A., 2006 | DAT1_P215 - DAT1_P+2459 - DAT1_I1+1036 - DAT1_I1+1735 - DAT1_I1+1859 | LMO3 | allelic P-value = 0....... allelic P-value = 0.187, genotypic P-value = 0.227 in the UCSD sample, allelic P-value = 0.381, genotypic P-value = 0.408 in the NIMH sample, allelic P-value = 0.039, genotypic P-value = 0.045 in the linked sample More... | Positive | ||
| Greenwood, T. A., 2006 | DAT1_P+2459 - DAT1_I1+1036 - DAT1_I1+1735 - DAT1_I1+1859 - DAT1_I1+1860 | LMO3 | allelic P-value = 0....... allelic P-value = 0.261, genotypic P-value = 0.513 in the UCSD sample, allelic P-value = 0.236, genotypic P-value = 0.267 in the NIMH sample, allelic P-value = 0.047, genotypic P-value = 0.06 in the linked sample More... | Positive | ||
| Greenwood, T. A., 2006 | DAT1_I9+102 - DAT1_I9 - 21 - DAT1_I10+117 - DAT1_I11+2078 - DAT1_I12+268 | T-G-G-C-G T-G-G-C-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.133, genotypic P-value = 0.117 in the UCSD sample, allelic P-value = 0.525, genotypic P-value = 0.374 in the NIMH sample, allelic P-value = 0.029, genotypic P-value = 0.022 in the linked sample; P-value = 0.015 in the linked sample More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I9+102 - DAT1_I9 - 21 - DAT1_I10+117 - DAT1_I11+2078 - DAT1_I12+268 | G-A-G-C-G G-A-G-C-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.133, genotypic P-value = 0.117 in the UCSD sample, allelic P-value = 0.525, genotypic P-value = 0.374 in the NIMH sample, allelic P-value = 0.029, genotypic P-value = 0.022 in the linked sample; P-value = 0.037 in the linked sample More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I9 - 21 - DAT1_I10+117 - DAT1_I11+2078 - DAT1_I12+268 - DAT1_I13 - 481 | G-G-C-G-G G-G-C-G-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.058, genotypic P-value = 0.176 in the UCSD sample, allelic P-value = 0.63, genotypic P-value = 0.172 in the NIMH sample, allelic P-value = 0.039, genotypic P-value = 0.043 in the linked sample; P-value = 0.002 in the linked sample More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I9 - 21 - DAT1_I10+117 - DAT1_I11+2078 - DAT1_I12+268 - DAT1_I13 - 481 | A-G-C-G-A A-G-C-G-A | LMO3 | allelic P-value = 0....... allelic P-value = 0.058, genotypic P-value = 0.176 in the UCSD sample, allelic P-value = 0.63, genotypic P-value = 0.172 in the NIMH sample, allelic P-value = 0.039, genotypic P-value = 0.043 in the linked sample; P-value = 0.037 in the linked sample More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I9 - 21 - DAT1_I10+117 - DAT1_I11+2078 - DAT1_I12+268 - DAT1_I13 - 481 | G-A-T-T-A G-A-T-T-A | LMO3 | allelic P-value = 0....... allelic P-value = 0.058, genotypic P-value = 0.176 in the UCSD sample, allelic P-value = 0.63, genotypic P-value = 0.172 in the NIMH sample, allelic P-value = 0.039, genotypic P-value = 0.043 in the linked sample; P-value = in the linked sample More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I8+2086 - DAT1_E9+59 - DAT1_I9+102 - DAT1_I9 - 21 - DAT1_I10+117 | A-G-T-G-G A-G-T-G-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.305, genotypic P-value = 0.052 in the UCSD sample, allelic P-value = 0.152, genotypic P-value = 0.156 in the NIMH sample, allelic P-value = 0.024, genotypic P-value = 0.055 in the linked sample; P-value = 0.013 in the linked sample More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I8+2086 - DAT1_E9+59 - DAT1_I9+102 - DAT1_I9 - 21 - DAT1_I10+117 | G-G-G-A-G G-G-G-A-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.305, genotypic P-value = 0.052 in the UCSD sample, allelic P-value = 0.152, genotypic P-value = 0.156 in the NIMH sample, allelic P-value = 0.024, genotypic P-value = 0.055 in the linked sample; P-value = 0.037 in the linked sample More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I7+922 - DAT1_I8+2086 - DAT1_E9+59 - DAT1_I9+102 - DAT1_I9 - 21 | C-A-G-T-G C-A-G-T-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.277, genotypic P-value = 0.04 in the UCSD sample, allelic P-value = 0.057, genotypic P-value = 0.003 in the NIMH sample, allelic P-value = 0.0001, genotypic P-value = 0.0003 in the linked sample; P-value = 0.033 in the linked sample More... | TDT analysis of the ...... TDT analysis of the sliding window haplotypes in the NIMH sample revealed empirical P-values<=0.003 for windows 5, 8, 9, and 10 under the genotypewise model. Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. Similar results were obtained using the allelewise model with empirical P-values of<=0.003 observed for windows 8, 9, 10, 12, and 19. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_I7+922 - DAT1_I8+2086 - DAT1_E9+59 - DAT1_I9+102 - DAT1_I9 - 21 | C-G-G-G-A C-G-G-G-A | LMO3 | allelic P-value = 0....... allelic P-value = 0.277, genotypic P-value = 0.04 in the UCSD sample, allelic P-value = 0.057, genotypic P-value = 0.003 in the NIMH sample, allelic P-value = 0.0001, genotypic P-value = 0.0003 in the linked sample; P-value = 0.014 in the linked sample More... | TDT analysis of the ...... TDT analysis of the sliding window haplotypes in the NIMH sample revealed empirical P-values<=0.003 for windows 5, 8, 9, and 10 under the genotypewise model. Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. Similar results were obtained using the allelewise model with empirical P-values of<=0.003 observed for windows 8, 9, 10, 12, and 19. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_I6+96 - DAT1_I7+922 - DAT1_I8+2086 - DAT1_E9+59 - DAT1_I9+102 | G-C-A-G-T G-C-A-G-T | LMO3 | allelic P-value = 0....... allelic P-value = 0.411, genotypic P-value = 0.002 in the UCSD sample, allelic P-value = 0.08, genotypic P-value = 0.001 in the NIMH sample, allelic P-value = 0.003, genotypic P-value = <0.00001 in the linked sample; P-value = 0.033 in the linked sample More... | TDT analysis of the ...... TDT analysis of the sliding window haplotypes in the NIMH sample revealed empirical P-values<=0.003 for windows 5, 8, 9, and 10 under the genotypewise model. Analysis of the UCSD sample also revealed strong evidence of association for window 9, which spans the region between introns 6 and 9, with an empirical P-value < =0.003 under the genotypewise model. The strongest evidence of association was observed for window 9 (P<0.00001), the window implicated in the analyses of the UCSD and NIMH samples independently. Similar results were obtained using the allelewise model with empirical P-values of<=0.003 observed for windows 8, 9, 10, 12, and 19. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_I5+448 - DAT1_I6+96 - DAT1_I7+922 - DAT1_I8+2086 - DAT1_E9+59 | G-G-C-A-G G-G-C-A-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.732, genotypic P-value = 0.286 in the UCSD sample, allelic P-value = 0.149, genotypic P-value = 0.0001 in the NIMH sample, allelic P-value = 0.003, genotypic P-value = 0.002 in the linked sample; P-value = 0.033 in the linked sample More... | TDT analysis of the ...... TDT analysis of the sliding window haplotypes in the NIMH sample revealed empirical P-values<=0.003 for windows 5, 8, 9, and 10 under the genotypewise model. Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. Similar results were obtained using the allelewise model with empirical P-values of<=0.003 observed for windows 8, 9, 10, 12, and 19. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_I2+48 - DAT1_I5+448 - DAT1_I6+96 - DAT1_I7+922 - DAT1_I8+2086 | A-G-G-C-A A-G-G-C-A | LMO3 | allelic P-value = 0....... allelic P-value = 0.867, genotypic P-value = 0.766 in the UCSD sample, allelic P-value = 0.308, genotypic P-value = 0.04 in the NIMH sample, allelic P-value = 0.008, genotypic P-value = 0.029 in the linked sample; P-value = 0.052 in the linked sample More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I14+4217 - DAT1_E15+274 - DAT1_E15+352 - DAT1_E15VNTR - DAT1_E15+1812 | A-C-G-9-C A-C-G-9-C | LMO3 | allelic P-value = 0....... allelic P-value = 0.109, genotypic P-value = 0.019 in the UCSD sample, allelic P-value = 0.372, genotypic P-value = 0.401 in the NIMH sample, allelic P-value = 0.0001, genotypic P-value = 0.0004 in the linked sample; P-value = 0.002 in the linked sample More... | Analysis of the slid...... Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. Similar results were obtained using the allelewise model with empirical P-values of<=0.003 observed for windows 8, 9, 10, 12, and 19. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_I13 - 481 - DAT1_I14+4217 - DAT1_E15+274 - DAT1_E15+352 - DAT1_E15VNTR | LMO3 | allelic P-value = 0....... allelic P-value = 0.182, genotypic P-value = 0.016 in the UCSD sample, allelic P-value = 0.134, genotypic P-value = 0.165 in the NIMH sample, allelic P-value = 0.011, genotypic P-value = 0.004 in the linked sample More... | Positive | ||
| Greenwood, T. A., 2006 | DAT1_I12+268 - DAT1_I13 - 481 - DAT1_I14+4217 - DAT1_E15+274 - DAT1_E15+352 | G-G-A-G-G G-G-A-G-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.264, genotypic P-value = 0.029 in the UCSD sample, allelic P-value = 0.441, genotypic P-value = 0.141 in the NIMH sample, allelic P-value = 0.012, genotypic P-value = 0.0003 in the linked sample; P-value = 0.055 in the linked sample More... | Analysis of the slid...... Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_I12+268 - DAT1_I13 - 481 - DAT1_I14+4217 - DAT1_E15+274 - DAT1_E15+352 | G-A-A-C-G G-A-A-C-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.264, genotypic P-value = 0.029 in the UCSD sample, allelic P-value = 0.441, genotypic P-value = 0.141 in the NIMH sample, allelic P-value = 0.012, genotypic P-value = 0.0003 in the linked sample; P-value = 0.025 in the linked sample More... | Analysis of the slid...... Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_I12+268 - DAT1_I13 - 481 - DAT1_I14+4217 - DAT1_E15+274 - DAT1_E15+352 | T-A-G-G-G T-A-G-G-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.264, genotypic P-value = 0.029 in the UCSD sample, allelic P-value = 0.441, genotypic P-value = 0.141 in the NIMH sample, allelic P-value = 0.012, genotypic P-value = 0.0003 in the linked sample; P-value = in the linked sample More... | Analysis of the slid...... Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_I11+2078 - DAT1_I12+268 - DAT1_I13 - 481 - DAT1_I14+4217 - DAT1_E15+274 | C-G-G-A-G C-G-G-A-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.362, genotypic P-value = 0.525 in the UCSD sample, allelic P-value = 0.562, genotypic P-value = 0.506 in the NIMH sample, allelic P-value = 0.034, genotypic P-value = 0.001 in the linked sample; P-value = 0.008 in the linked sample More... | Analysis of the slid...... Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_I11+2078 - DAT1_I12+268 - DAT1_I13 - 481 - DAT1_I14+4217 - DAT1_E15+274 | C-G-A-A-C C-G-A-A-C | LMO3 | allelic P-value = 0....... allelic P-value = 0.362, genotypic P-value = 0.525 in the UCSD sample, allelic P-value = 0.562, genotypic P-value = 0.506 in the NIMH sample, allelic P-value = 0.034, genotypic P-value = 0.001 in the linked sample; P-value = 0.008 in the linked sample More... | Analysis of the slid...... Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_I11+2078 - DAT1_I12+268 - DAT1_I13 - 481 - DAT1_I14+4217 - DAT1_E15+274 | T-T-A-G-G T-T-A-G-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.362, genotypic P-value = 0.525 in the UCSD sample, allelic P-value = 0.562, genotypic P-value = 0.506 in the NIMH sample, allelic P-value = 0.034, genotypic P-value = 0.001 in the linked sample; P-value = in the linked sample More... | Analysis of the slid...... Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_I10+117 - DAT1_I11+2078 - DAT1_I12+268 - DAT1_I13 - 481 - DAT1_I14+4217 | G-C-G-G-A G-C-G-G-A | LMO3 | allelic P-value = 0....... allelic P-value = 0.156, genotypic P-value = 0.209 in the UCSD sample, allelic P-value = 0.777, genotypic P-value = 0.551 in the NIMH sample, allelic P-value = 0.058, genotypic P-value = 0.06 in the linked sample; P-value = 0.005 in the linked sample More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I10+117 - DAT1_I11+2078 - DAT1_I12+268 - DAT1_I13 - 481 - DAT1_I14+4217 | G-C-G-A-A G-C-G-A-A | LMO3 | allelic P-value = 0....... allelic P-value = 0.156, genotypic P-value = 0.209 in the UCSD sample, allelic P-value = 0.777, genotypic P-value = 0.551 in the NIMH sample, allelic P-value = 0.058, genotypic P-value = 0.06 in the linked sample; P-value = 0.025 in the linked sample More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I10+117 - DAT1_I11+2078 - DAT1_I12+268 - DAT1_I13 - 481 - DAT1_I14+4217 | A-T-T-A-G A-T-T-A-G | LMO3 | allelic P-value = 0....... allelic P-value = 0.156, genotypic P-value = 0.209 in the UCSD sample, allelic P-value = 0.777, genotypic P-value = 0.551 in the NIMH sample, allelic P-value = 0.058, genotypic P-value = 0.06 in the linked sample; P-value = in the linked sample More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I1+1860 - DAT1_I2+48 - DAT1_I5+448 - DAT1_I6+96 - DAT1_I7+922 | LMO3 | allelic P-value = 0....... allelic P-value = 0.341, genotypic P-value = 0.438 in the UCSD sample, allelic P-value = 0.148, genotypic P-value = 0.492 in the NIMH sample, allelic P-value = 0.027, genotypic P-value = 0.001 in the linked sample More... | Analysis of the UCSD...... Analysis of the UCSD sample also revealed strong evidence of association for window 9, which spans the region between introns 6 and 9, with an empirical P-value < =0.003 under the genotypewise model. Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I1+1859 - DAT1_I1+1860 - DAT1_I2+48 - DAT1_I5+448 - DAT1_I6+96 | LMO3 | allelic P-value = 0....... allelic P-value = 0.109, genotypic P-value = 0.244 in the UCSD sample, allelic P-value = 0.048, genotypic P-value = 0.001 in the NIMH sample, allelic P-value = 0.12, genotypic P-value = 0.001 in the linked sample More... | TDT analysis of the ...... TDT analysis of the sliding window haplotypes in the NIMH sample revealed empirical P-values<=0.003 for windows 5, 8, 9, and 10 under the genotypewise model. Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. More... | Positive | |
| Greenwood, T. A., 2006 | DAT1_I1+1735 - DAT1_I1+1859 - DAT1_I1+1860 - DAT1_I2+48 - DAT1_I5+448 | LMO3 | allelic P-value = 0....... allelic P-value = 0.074, genotypic P-value = 0.102 in the UCSD sample, allelic P-value = 0.258, genotypic P-value = 0.005 in the NIMH sample, allelic P-value = 0.305, genotypic P-value = 0.025 in the linked sample More... | Positive | ||
| Greenwood, T. A., 2006 | DAT1_I1+1036 - DAT1_I1+1735 - DAT1_I1+1859 - DAT1_I1+1860 - DAT1_I2+48 | LMO3 | allelic P-value = 0....... allelic P-value = 0.154, genotypic P-value = 0.097 in the UCSD sample, allelic P-value = 0.096, genotypic P-value = 0.013 in the NIMH sample, allelic P-value = 0.115, genotypic P-value = 0.258 in the linked sample More... | Positive | ||
| Greenwood, T. A., 2006 | DAT1_E9+59 - DAT1_I9+102 - DAT1_I9 - 21 - DAT1_I10+117 - DAT1_I11+2078 | G-T-G-G-C G-T-G-G-C | LMO3 | allelic P-value = 0....... allelic P-value = 0.046, genotypic P-value = 0.02 in the UCSD sample, allelic P-value = 0.631, genotypic P-value = 0.574 in the NIMH sample, allelic P-value = 0.003, genotypic P-value = 0.003 in the linked sample; P-value = 0.013 in the linked sample More... | Analysis of the slid...... Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. Similar results were obtained using the allelewise model with empirical P-values of<=0.003 observed for windows 8, 9, 10, 12, and 19. More... | Positive |
| Greenwood, T. A., 2006 | DAT1_E9+59 - DAT1_I9+102 - DAT1_I9 - 21 - DAT1_I10+117 - DAT1_I11+2078 | G-G-A-G-C G-G-A-G-C | LMO3 | allelic P-value = 0....... allelic P-value = 0.046, genotypic P-value = 0.02 in the UCSD sample, allelic P-value = 0.631, genotypic P-value = 0.574 in the NIMH sample, allelic P-value = 0.003, genotypic P-value = 0.003 in the linked sample; P-value = 0.037 in the linked sample More... | Analysis of the slid...... Analysis of the sliding windows in the Linked sample revealed empirical P-values<=0.003 for windows 5, 6, 8, 10, 12, 16, 17, and 19 under the genotypewise model. Similar results were obtained using the allelewise model with empirical P-values of<=0.003 observed for windows 8, 9, 10, 12, and 19. More... | Positive |
| Abou Jamra, R.,2007 | D6S1626 - D2S381 | 2q22-q24, 6q23-q24 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 6q as conditional markers, interaction NPL score=6.07; STRs on 2q as conditional markers, interaction NPL score=7.36 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D6S1626 - D2S222 | 2q22-q24, 6q23-q24 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 6q as conditional markers, interaction NPL score=6.1; STRs on 2q as conditional markers, interaction NPL score=7.34 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D6S1626 - D2S1399 | 2q22-q24, 6q23-q24 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 6q as conditional markers, interaction NPL score=6.09; STRs on 2q as conditional markers, interaction NPL score=7.55 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D6S1587 - D2S381 | 2q22-q24, 6q23-q24 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 6q as conditional markers, interaction NPL score=6.63; STRs on 2q as conditional markers, interaction NPL score=7.39 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D6S1587 - D2S222 | 2q22-q24, 6q23-q24 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 6q as conditional markers, interaction NPL score=6.69; STRs on 2q as conditional markers, interaction NPL score=7.38 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D6S1587 - D2S1399 | 2q22-q24, 6q23-q24 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 6q as conditional markers, interaction NPL score=6.69; STRs on 2q as conditional markers, interaction NPL score=7.66 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D6S1009 - D2S381 | 2q22-q24, 6q23-q24 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 6q as conditional markers, interaction NPL score=6.67; STRs on 2q as conditional markers, interaction NPL score=7.64 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D6S1009 - D2S2275 | 2q22-q24, 6q23-q24 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 6q as conditional markers, interaction NPL score=6.81; STRs on 2q as conditional markers, interaction NPL score=7.37 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D6S1009 - D2S222 | 2q22-q24, 6q23-q24 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 6q as conditional markers, interaction NPL score=6.7; STRs on 2q as conditional markers, interaction NPL score=7.39 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D6S1009 - D2S1399 | 2q22-q24, 6q23-q24 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 6q as conditional markers, interaction NPL score=6.69; STRs on 2q as conditional markers, interaction NPL score=7.51 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Fullerton, J. M.,2010 | D4S419 - D12S78 | 4q15, 12q21 | Interaction-Specific...... Interaction-Specific Linkage:at Marker D4S419, equal NPL-pair=0.8546, interacting locus NPL-pairs=3.1641, permuted P-value = -0.0002; at Marker D12S78, equal NPL-pair=1.1055, interacting locus NPL-pairs=2.449, permuted P-value = -0.0002 More... | Positive linkage was...... Positive linkage was found in this region.(significant:NPL=2.8, suggestive:NPL=2.5) More... | Positive | |
| Als, T. D.,2004 | D4S403 - D4S3048 | 4p16.1 | Two-marker associati...... Two-marker association:P-value = 0.0500 More... | No significant asso...... No significant association was found . More... | Negative | |
| Als, T. D.,2004 | D4S394 - D4S2983 | 4p16.1 | Two-marker associati...... Two-marker association:P-value = 0.0162 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Georgi, B., 2014 | D4S3360 - D4S2936 - D4S412 | 4-5-5, 5-4-6, 5-3-2,...... 4-5-5, 5-4-6, 5-3-2, 4-2-2 More... | HLOD 3.96 HLOD 3.96 | The notable exceptio...... The notable exception to this was the three-marker haplotype on 4p16.3 (D4S3360-D4S2936-D4S412) covering the highest observed linkage peak (HLOD 3.96). Among the four contributing haplotypes (4-5-5, 5-4-6, 5-3-2, 4-2-2 at above listed microsatellite loci), a single haplotype, 5-3-2, was shared by 3 out of 4 linked nuclear families. More... | Positive | |
| Als, T. D.,2004 | D4S2923 - D4S2928 - D4S1582 | 4p16.1 | Three-marker associa...... Three-marker association:P-value = 0.0110 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Als, T. D.,2004 | D4S2281 - D4S1506 | 4p16.1 | Two-marker associati...... Two-marker association:P-value = 0.1550 More... | No significant asso...... No significant association was found . More... | Negative | |
| Fullerton, J. M.,2010 | D4S1597 - D1S468 | 4q35, 1p36 | Interaction-Specific...... Interaction-Specific Linkage:at Marker D4S1597, equal NPL-pair=2.3352, interacting locus NPL-pairs=3.2785, permuted P-value = 0.0003; at Marker D1S468, equal NPL-pair=0.4511, interacting locus NPL-pairs=1.7052, permuted P-value = 0.003 More... | Positive linkage was...... Positive linkage was found in this region.(significant:NPL=2.8, suggestive:NPL=2.5) More... | Positive | |
| Fullerton, J. M.,2010 | D2S337 - D11S925 | 2p14, 11q23 | Interaction-Specific...... Interaction-Specific Linkage:at Marker D2S337, equal NPL-pair=0.5866, interacting locus NPL-pairs=2.202, permuted P-value = 0.0005; at Marker D11S925, equal NPL-pair=1.9459, interacting locus NPL-pairs=2.9547, permuted P-value = 0.002 More... | Positive linkage was...... Positive linkage was found in this region.(significant:NPL=2.8, suggestive:NPL=2.5) More... | Positive | |
| Severinsen, J. E., 2006 (b) | D22S922 - D22S1169 - rs4468 | 2-3-C 2-3-C | BRD1 | P-value = 0.0248 in ...... P-value = 0.0248 in BD and SZ More... | Positive | |
| Severinsen, J. E., 2006 (b) | D22S922 - rs132234 | FAM19A5 | P-value = 0.892 in B...... P-value = 0.892 in BD, P-value = 0.5738 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (a) | D22S279 - rs909669 | ADSL | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.0805, CLUMP T4 P-value = 0.0501 in BPD and SZ, CLUMP T1 P-value = 0.4799, CLUMP T4 P-value = 0.3873 in BPD; Empirical overall P-value = 0.049 in BPD and SZ, Empirical overall P-value = 0.058 in BPD More... | Similarly, comparing...... Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL. More... | Positive | |
| Severinsen, J. E., 2006 (a) | D22S279 - rs133068 - rs133069 - rs133070 - rs133073 | 7-C-C-A-T 7-C-C-A-T | MCHR1 | CLUMP P-value = 0.28...... CLUMP P-value = 0.2868 in BPD, P-value = 0.0139 in BPD and SZ; risk haplotype More... | Positive | |
| Severinsen, J. E., 2006 (a) | D22S279 - rs133068 - rs133069 - rs133070 - rs133073 | 6-C-C-A-T 6-C-C-A-T | MCHR1 | CLUMP P-value = 0.03...... CLUMP P-value = 0.034 in BPD, P-value = 0.2166 in BPD and SZ; risk haplotype More... | Positive | |
| Severinsen, J. E., 2006 (a) | D22S279 - rs133068 - rs133069 - rs133070 - rs133073 | 6/7-C-C-A-T 6/7-C-C-A-T | MCHR1 | CLUMP P-value = 0.00...... CLUMP P-value = 0.0076 in BPD, P-value = 0.0005 in BPD and SZ; risk haplotype More... | Positive | |
| Severinsen, J. E., 2006 (b) | D22S1169 - D22S922 - rs132234 | FAM19A5 | P-value = 0.4032 in ...... P-value = 0.4032 in BD, P-value = 0.4635 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | D22S1169 - D22S922 | P-value = 0.6196 in ...... P-value = 0.6196 in BD, P-value = 0.427 in BD and SZ More... | Negative | |||
| Fullerton, J. M.,2010 | D20S196 - D9S167 | 20q13, 9q21 | Interaction-Specific...... Interaction-Specific Linkage:at Marker D20S196, equal NPL-pair=1.5602, interacting locus NPL-pairs=2.4261, permuted P-value = 0.0004; at Marker D9S167, equal NPL-pair=0.0623, interacting locus NPL-pairs=2.3812, permuted P-value = 0.0004 More... | No positive linkage ...... No positive linkage was found in this region(significant:NPL=2.8, suggestive:NPL=2.5). More... | Negative | |
| Abou Jamra, R.,2007 | D15S642 - D2S381 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.56; STRs on 2q as conditional markers, interaction NPL score=3.78 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D15S642 - D2S2950 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.96; STRs on 2q as conditional markers, interaction NPL score=3.5 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D15S642 - D2S2334 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.86; STRs on 2q as conditional markers, interaction NPL score=3.52 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D15S642 - D2S222 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.58; STRs on 2q as conditional markers, interaction NPL score=3.77 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Abou Jamra, R.,2007 | D15S642 - D2S1399 | 2q22-q24, 15q26 | Interaction Linkage ...... Interaction Linkage Analysis:STRs on 15q as conditional markers, interaction NPL score=5.58; STRs on 2q as conditional markers, interaction NPL score=3.79 More... | Positive linkage was...... Positive linkage was found in this region. More... | Positive | |
| Degn, B.,2001 | D12S76 - D12S1349 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.091, P-value(T4)=0.238 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S386 - D12S1634 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.045, P-value(T4)=0.074 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S342 - D12S340 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.316, P-value(T4)=0.234 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S340 - D12S1639 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.592, P-value(T4)=0.748 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S324 - D12S386 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.449, P-value(T4)=0.595 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S307 - D12S1658 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.211, P-value(T4)=0.221 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S2075 - D12S1675 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.0007, P-value(T4)=0.001 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Degn, B.,2001 | D12S1675 - D12S1659 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.138, P-value(T4)=0.186 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S1659 - D12S97 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.549, P-value(T4)=0.481 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S1658 - GATA41E12 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.472, P-value(T4)=0.511 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S1639 - D12S324 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.43, P-value(T4)=0.546 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S1634 - D12S307 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.084, P-value(T4)=0.061 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S1614 - D12S342 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.007, P-value(T4)=0.003 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Degn, B.,2001 | D12S1612 - D12S1614 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.167, P-value(T4)=0.142 More... | No significant asso...... No significant association was found . More... | Negative | |
| Degn, B.,2001 | D12S1349 - D12S1612 | 12q24 | Two-marker haplotype...... Two-marker haplotypes:P-value(T1)=0.227, P-value(T4)=0.175 More... | No significant asso...... No significant association was found . More... | Negative | |
| De Luca, V., 2007 | CRHR2_intron 4_(CA)n - CRHR2_intron10_(GAT)n - CRHR2_intron10_(GT)n | 5-7-8 5-7-8 | CRHR2 | FBAT P-value = 0.01,...... FBAT P-value = 0.01, Z=2.57 More... | the haplotype 5-7-8 ...... the haplotype 5-7-8 was associated with the disease More... | Positive |
| De Luca, V., 2007 | CRHR2_intron 4_(CA)n - CRHR2_intron10_(GAT)n - CRHR2_intron10_(GT)n | 5-2-3 5-2-3 | CRHR2 | FBAT P-value = 0.004...... FBAT P-value = 0.004, Z=-2.853 More... | the haplotype 5-2-3 ...... the haplotype 5-2-3 was protective More... | Positive |
| De Luca, V., 2007 | CRHR2_intron 4_(CA)n - CRHR2_intron10_(GAT)n - CRHR2_intron10_(GT)n | 5-7-7 5-7-7 | CRHR2 | FBAT P-value = 0.781...... FBAT P-value = 0.781, Z=0.279 More... | yielded non-signific...... yielded non-significant results More... | Negative |
| De Luca, V., 2007 | CRHR2_intron 4_(CA)n - CRHR2_intron10_(GAT)n - CRHR2_intron10_(GT)n | 5-3-6 5-3-6 | CRHR2 | FBAT P-value = 0.879...... FBAT P-value = 0.879, Z=0.152 More... | yielded non-signific...... yielded non-significant results More... | Negative |
| De Luca, V., 2007 | CRHR2_intron 4_(CA)n - CRHR2_intron10_(GAT)n - CRHR2_intron10_(GT)n | 3-3-7 3-3-7 | CRHR2 | FBAT P-value = 0.655...... FBAT P-value = 0.655, Z=0.447 More... | yielded non-signific...... yielded non-significant results More... | Negative |
| De Luca, V., 2007 | CRHR2_intron 4_(CA)n - CRHR2_intron10_(GAT)n - CRHR2_intron10_(GT)n | 5-3-3 5-3-3 | CRHR2 | FBAT P-value = 0.84,...... FBAT P-value = 0.84, Z=0.202 More... | yielded non-signific...... yielded non-significant results More... | Negative |
| De Luca, V., 2007 | CRHR2_intron 4_(CA)n - CRHR2_intron10_(GAT)n - CRHR2_intron10_(GT)n | 5-2-5 5-2-5 | CRHR2 | FBAT P-value = 0.132...... FBAT P-value = 0.132, Z=-1.508 More... | yielded non-signific...... yielded non-significant results More... | Negative |
| Lohoff, F. W., 2008 (b) | common haplotypes | ACA ACA | VAPA | X<sup>2</su...... X<sup>2</sup>=0.318, P-value =0.5726, Permutation P-value =0.9827 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease after permutation correction. More... | Negative |
| Lohoff, F. W., 2008 (b) | common haplotypes | CAC CAC | VAPA | X<sup>2</su...... X<sup>2</sup>=1.223, P-value =0.2687, Permutation P-value =0.8168 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease after permutation correction. More... | Negative |
| Lohoff, F. W., 2008 (b) | common haplotypes | AAA AAA | VAPA | X<sup>2</su...... X<sup>2</sup>=0.158, P-value =0.6913, Permutation P-value =0.9974 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease after permutation correction. More... | Negative |
| Lohoff, F. W., 2008 (b) | common haplotypes | CAA CAA | VAPA | X<sup>2</su...... X<sup>2</sup>=1.565, P-value =0.2109, Permutation P-value =0.745 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease after permutation correction. More... | Negative |
| Lohoff, F. W., 2008 (b) | common haplotypes | AA AA | VAPA | X<sup>2</su...... X<sup>2</sup>=5.322, P-value =0.0211, Permutation P-value =0.0821 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease after permutation correction. More... | Positive |
| Lohoff, F. W., 2008 (b) | common haplotypes | CC CC | VAPA | X<sup>2</su...... X<sup>2</sup>=4.897, P-value =0.0269, Permutation P-value =0.0994 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease after permutation correction. More... | Positive |
| Mathieu, F., 2008 | CC33 - CCS3 | PPP3CC | Global X<sup>2...... Global X<sup>2</sup>=9.08, df=3, P-value = 0.03. More... | Haplotype frequencie...... Haplotype frequencies were significantly different in BPAD patients than in controls. More... | Positive | |
| Mathieu, F., 2008 | CC33 - CCS3 | TG TG | PPP3CC | X<sup>2</su...... X<sup>2</sup>=16.2, P-value =0.001 when TG versus (C2+CG+TA) More... | A significant over-t...... A significant over-transmission of the PPP3CC haplotype 'TG' was observed for bipolar patients. More... | Positive |
| Muller, D. J., 2006 | BDNF_Val66Met - BDNF_GT(n) | G-3 G-3 | BDNF | TDTPHASE P-value = 0...... TDTPHASE P-value = 0.0008, X<sup>2</sup>=11.2, RR=2.29 More... | The strongest result...... The strongest results were obtained when the Val allele was combined with either marker hCV11592756 or allele 3 of the GT(n) repeat polymorphism. More... | Positive |
| Okada, T., 2006 | BDNF_LCPR - BDNF_Val66Met | A1-Val A1-Val | BDNF | chi-square P-value =...... chi-square P-value = 0.001, df=1, global P-value = 0.0069 More... | The haplotype-based ...... The haplotype-based association analysis yielded a significant result (global P=0.0069) estimated by the permutation test, correcting for multiple testing. Since the A1 allele was completely linked to the Val66 allele, the most significant individual P-value of 0.001 was obtained when the A1-Val66 was assumed to be the risk. More... | Positive |
| Okada, T., 2006 | BDNF_LCPR - BDNF_Val66Met | A2-Val A2-Val | BDNF | chi-square P-value =...... chi-square P-value = 0.054, df=1, global P-value = 0.0069 More... | The haplotype-based ...... The haplotype-based association analysis yielded a significant result (global P=0.0069) estimated by the permutation test, correcting for multiple testing. More... | Negative |
| Okada, T., 2006 | BDNF_LCPR - BDNF_Val66Met | A3-Val A3-Val | BDNF | chi-square P-value =...... chi-square P-value = 0.53, df=1, global P-value = 0.0069 More... | The haplotype-based ...... The haplotype-based association analysis yielded a significant result (global P=0.0069) estimated by the permutation test, correcting for multiple testing. More... | Negative |
| Okada, T., 2006 | BDNF_LCPR - BDNF_Val66Met | A4-Val A4-Val | BDNF | chi-square P-value =...... chi-square P-value = 0.23, df=1, global P-value = 0.0069 More... | The haplotype-based ...... The haplotype-based association analysis yielded a significant result (global P=0.0069) estimated by the permutation test, correcting for multiple testing. More... | Negative |
| Okada, T., 2006 | BDNF_LCPR - BDNF_Val66Met | A4-Met A4-Met | BDNF | chi-square P-value =...... chi-square P-value = 0.61, df=1, global P-value = 0.0069 More... | The haplotype-based ...... The haplotype-based association analysis yielded a significant result (global P=0.0069) estimated by the permutation test, correcting for multiple testing. More... | Negative |
| Okada, T., 2006 | BDNF_LCPR - BDNF_Val66Met | A5-Val A5-Val | BDNF | chi-square P-value =...... chi-square P-value = 0.62, df=1, global P-value = 0.0069 More... | The haplotype-based ...... The haplotype-based association analysis yielded a significant result (global P=0.0069) estimated by the permutation test, correcting for multiple testing. More... | Negative |
| Okada, T., 2006 | BDNF_LCPR - BDNF_Val66Met | A5-Met A5-Met | BDNF | chi-square P-value =...... chi-square P-value = 1, df=1, global P-value = 0.0069 More... | The haplotype-based ...... The haplotype-based association analysis yielded a significant result (global P=0.0069) estimated by the permutation test, correcting for multiple testing. More... | Negative |
| Muller, D. J., 2006 | BDNF_hCV11592756 - BDNF_Val66Met - BDNF_GT(n) - rs2049045 | A-G-3-G A-G-3-G | BDNF | TDTPHASE P-value = 0...... TDTPHASE P-value = 0.008, X<sup>2</sup>=6.37, RR=0.36 More... | The A-Val-3-G haplot...... The A-Val-3-G haplotype proved to be significantly overtransmitted (49:25) in participants with bipolar disorder. More... | Positive |
| Muller, D. J., 2006 | BDNF_hCV11592756 - BDNF_Val66Met - BDNF_GT(n) | A-G-3 A-G-3 | BDNF | TDTPHASE P-value = 0...... TDTPHASE P-value = 0.008, X<sup>2</sup>=7.04, RR=0.37 More... | Positive | |
| Muller, D. J., 2006 | BDNF_hCV11592756 - BDNF_Val66Met - rs2049045 | A-G-G A-G-G | BDNF | TDTPHASE P-value = 0...... TDTPHASE P-value = 0.001, X<sup>2</sup>=10.43, RR=2.13 More... | Positive | |
| Muller, D. J., 2006 | BDNF_hCV11592756 - BDNF_Val66Met | A-G A-G | BDNF | TDTPHASE P-value = 0...... TDTPHASE P-value = 0.0008, X<sup>2</sup>=11.09, RR=1.54 More... | The strongest result...... The strongest results were obtained when the Val allele was combined with either marker hCV11592756 or allele 3 of the GT(n) repeat polymorphism. More... | Positive |
| Muller, D. J., 2006 | BDNF_hCV11592756 - rs2049045 | A-G A-G | BDNF | TDTPHASE P-value = 0...... TDTPHASE P-value = 0.01, X<sup>2</sup>=6.46, RR=1.41 More... | Positive | |
| Vincze, I., N., 2008 | BDNF-LCPR - A-633T - G196A | STG STG | BDNF | X<sup>2</su...... X<sup>2</sup>=0.014; P-value = 0.9054 More... | There was no differe...... There was no difference in the distribution of haplotype frequencies between BD and control groups, in contrast with previous studies on BDNF-LCPR-G196A haplotype. More... | Negative |
| Vincze, I., N., 2008 | BDNF-LCPR - A-633T - G196A | SAG SAG | BDNF | X<sup>2</su...... X<sup>2</sup>=0.003; P-value = 0.9539 More... | There was no differe...... There was no difference in the distribution of haplotype frequencies between BD and control groups, in contrast with previous studies on BDNF-LCPR-G196A haplotype. More... | Negative |
| Vincze, I., N., 2008 | BDNF-LCPR - A-633T - G196A | LAA LAA | BDNF | X<sup>2</su...... X<sup>2</sup>=0.235; P-value = 0.6282 More... | There was no differe...... There was no difference in the distribution of haplotype frequencies between BD and control groups, in contrast with previous studies on BDNF-LCPR-G196A haplotype. More... | Negative |
| Vincze, I., N., 2008 | BDNF-LCPR - A-633T - G196A | LAG LAG | BDNF | X<sup>2</su...... X<sup>2</sup>=1.006; P-value = 0.3158 More... | There was no differe...... There was no difference in the distribution of haplotype frequencies between BD and control groups, in contrast with previous studies on BDNF-LCPR-G196A haplotype. More... | Negative |
| Vincze, I., N., 2008 | BDNF-LCPR - A-633T - G196A | SAA SAA | BDNF | X<sup>2</su...... X<sup>2</sup>=0.528; P-value = 0.4676 More... | There was no differe...... There was no difference in the distribution of haplotype frequencies between BD and control groups, in contrast with previous studies on BDNF-LCPR-G196A haplotype. More... | Negative |
| Vincze, I., N., 2008 | BDNF-LCPR - A-633T - G196A | STA STA | BDNF | X<sup>2</su...... X<sup>2</sup>=0.04; P-value = 0.842 More... | There was no differe...... There was no difference in the distribution of haplotype frequencies between BD and control groups, in contrast with previous studies on BDNF-LCPR-G196A haplotype. More... | Negative |
| Vincze, I., N., 2008 | BDNF-LCPR - A-633T - G196A | LTG LTG | BDNF | X<sup>2</su...... X<sup>2</sup>=2.212; P-value = 0.137 More... | There was no differe...... There was no difference in the distribution of haplotype frequencies between BD and control groups, in contrast with previous studies on BDNF-LCPR-G196A haplotype. More... | Negative |
| Kalsi, G., 2006 | AY070435_29818-insT - AY070435_307CA1 | AY070435 | global P-value = 0.0...... global P-value = 0.0013 More... | Two-marker haplotype...... Two-marker haplotype analysis using 29818-insT and 307CA1 produced a significant empirical p value of 0.0013 and estimated that 35% of bipolar patient chromosomes carry the 12 (BP6) haplotype and for this haplotype to occur in 27% of comparison chromosomes. This suggests that the BP6 haplotype may carry an elevated risk for bipolar disorder. More... | Positive | |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 - ALG9_D11S5027 | 1-1-1 1-1-1 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.78 in PITT More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 - ALG9_D11S5027 | 3-1-1 3-1-1 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.9 in PITT More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 - ALG9_D11S5027 | 4-1-1 4-1-1 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.7 in PITT More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 - ALG9_D11S5027 | 5-1-1 5-1-1 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.13 in PITT More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 - ALG9_D11S5027 | 2-1-4 2-1-4 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.81 in PITT More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 - ALG9_D11S5027 | 2-2-2 2-2-2 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.82 in PITT More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 - ALG9_D11S5027 | 2-2-3 2-2-3 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.55 in PITT More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 | 1-1 1-1 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.67 in NIMH More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 | 3-1 3-1 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.98 in NIMH More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 | 4-1 4-1 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.62 in NIMH More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 | 5-1 5-1 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.67 in NIMH More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 | 2-2 2-2 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.78 in NIMH More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Baysal, B. E., 2006 | ALG9_D11S5028 - rs10502151 | 5-2 5-2 | ALG9 | Haplotype transmissi...... Haplotype transmission disequlibrium P-value = 0.87 in NIMH More... | None of the haplotyp...... None of the haplotypes showed statistically significant evidence of transmission disequilibrium to offspring affected by bipolar I. More... | Negative |
| Lee, S. Y.,2010 | ALDH2_*1/*2 - rs1800497 | (ALDH2_1*1*)-(DRD2 T...... (ALDH2_1*1*)-(DRD2 Taq-I A1/A2) More... | ALDH2 DRD2 | Logistic regression ...... Logistic regression analysis:for BP-I, OR=1.201, 95%CI=0.519-2.779, P-value = 0.669; for BP-II, OR=1.353, 95%CI=0.531-2.502, P-value = 0.719 More... | No significant asso...... No significant association was found . More... | Negative |
| Lee, S. Y.,2010 | ALDH2_*1/*2 - rs1800497 | (ALDH2_1*1*)-(DRD2Ta...... (ALDH2_1*1*)-(DRD2Taq-I A1/A1) More... | ALDH2 DRD2 | Logistic regression ...... Logistic regression analysis:for BP-I, OR=2.043, 95%CI=0.622-6.710, P-value = 0.239; for BP-II, OR=4.534, 95%CI=1.455-14.129, P-value = 0.009 More... | Significant associat...... Significant association was found in BD-II. More... | Positive |
| Kim, S. H.,2011 | rs9990 - rs1509963 - rs2295814 - rs61865882 - rs45602133 | C-G-G-T-T C-G-G-T-T | EGR2 | Haplotype analysis:O...... Haplotype analysis:OR=0.805, X<sup>2</sup>=4.126, P-value = 0.0422 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Kim, S. H.,2011 | rs9990 - rs1509963 - rs2295814 - rs61865882 - rs45602133 | T-A-G-T-G T-A-G-T-G | EGR2 | Haplotype analysis:O...... Haplotype analysis:OR=1.021, X<sup>2</sup>=0.017, P-value = 0.8973 More... | No significant asso...... No significant association was found . More... | Negative |
| Kim, S. H.,2011 | rs9990 - rs1509963 - rs2295814 - rs61865882 - rs45602133 | T-A-G-T-T T-A-G-T-T | EGR2 | Haplotype analysis:O...... Haplotype analysis:OR=0.966, X<sup>2</sup>=0.075, P-value = 0.7843 More... | No significant asso...... No significant association was found . More... | Negative |
| Kim, S. H.,2011 | rs9990 - rs1509963 - rs2295814 - rs61865882 - rs45602133 | T-G-A-C-T T-G-A-C-T | EGR2 | Haplotype analysis:O...... Haplotype analysis:OR=1.736, X<sup>2</sup>=8.548, P-value = 0.0035 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Roche, S., 2007 | rs9984977 - rs4818917 | TRPM2 | TDT P-value = 0.132,...... TDT P-value = 0.132, X<sup>2</sup>=4.051 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| Roche, S., 2007 | rs9974831 - rs1785454 | TRPM2 | TDT P-value = 0.416,...... TDT P-value = 0.416, X<sup>2</sup>=2.847 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| Feng, Y., 2008 | rs991729 - rs3784410 | NTRK3 | Global X<sup>2...... Global X<sup>2</sup>=5.442, df=3, p=0.142. For haplotypes with frequencies greater than 10%, X<sup>2</sup>=5.442, df=3, p=0.142. More... | Negative | ||
| Feng, Y., 2008 | rs991729 - rs3784410 | GT GT | NTRK3 | haplotype GT P-value...... haplotype GT P-value = 0.038, X<sup>2</sup>(df=1)=4.310 More... | Positive | |
| Feng, Y., 2008 | rs991729 - rs3784410 | GC GC | NTRK3 | haplotype GC P-value...... haplotype GC P-value = 0.141, X<sup>2</sup>(df=1)=2.170 More... | Negative | |
| Feng, Y., 2008 | rs991729 - rs3784410 | AC AC | NTRK3 | haplotype AC P-value...... haplotype AC P-value = 0.436, X<sup>2</sup>(df=1)=0.608 More... | Negative | |
| Schumacher, J.,2005 | rs988748 - BDNF_(GT)n - rs6265 | C-166bp-G C-166bp-G | BDNF | Haplotypic associati...... Haplotypic association:in Bonn sample, for BPAD, global P-value = 0.0057, Bonferroni-Corrected P-value = 0.0684, individual P-value = 0.975 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Schumacher, J.,2005 | rs988748 - BDNF_(GT)n - rs6265 | C-168bp-G C-168bp-G | BDNF | Haplotypic associati...... Haplotypic association:in Bonn sample, for BPAD, global P-value = 0.0057, Bonferroni-Corrected P-value = 0.0684, individual P-value = 0.821 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Schumacher, J.,2005 | rs988748 - BDNF_(GT)n - rs6265 | C-170bp-G C-170bp-G | BDNF | Haplotypic associati...... Haplotypic association:in Bonn sample, for BPAD, global P-value = 0.0057, Bonferroni-Corrected P-value = 0.0684, individual P-value = 0.499 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Schumacher, J.,2005 | rs988748 - BDNF_(GT)n - rs6265 | C-172bp-G C-172bp-G | BDNF | Haplotypic associati...... Haplotypic association:in Bonn sample, for BPAD, global P-value = 0.0057, Bonferroni-Corrected P-value = 0.0684, individual P-value = 0.341 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Schumacher, J.,2005 | rs988748 - BDNF_(GT)n - rs6265 | C-174bp-G C-174bp-G | BDNF | Haplotypic associati...... Haplotypic association:in Bonn sample, for BPAD, global P-value = 0.0057, Bonferroni-Corrected P-value = 0.0684, individual P-value = 0.077 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Schumacher, J.,2005 | rs988748 - BDNF_(GT)n - rs6265 | G-170bp-A G-170bp-A | BDNF | Haplotypic associati...... Haplotypic association:in Bonn sample, for BPAD, global P-value = 0.0057, Bonferroni-Corrected P-value = 0.0684, individual P-value = 0.005 More... | Significant associat...... Significant association was found in both global P-value and individual P-value. More... | Positive |
| Schumacher, J.,2005 | rs988748 - BDNF_(GT)n - rs6265 | G-174bp-A G-174bp-A | BDNF | Haplotypic associati...... Haplotypic association:in Bonn sample, for BPAD, global P-value = 0.0057, Bonferroni-Corrected P-value = 0.0684, individual P-value = 0.353 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Schumacher, J.,2005 | rs988748 - BDNF_(GT)n - rs6265 | G-174bp-G G-174bp-G | BDNF | Haplotypic associati...... Haplotypic association:in Bonn sample, for BPAD, global P-value = 0.0057, Bonferroni-Corrected P-value = 0.0684, individual P-value = 0.969 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Schumacher, J.,2005 | rs988748 - BDNF_(GT)n - rs6265 | G-176bp-A G-176bp-A | BDNF | Haplotypic associati...... Haplotypic association:in Bonn sample, for BPAD, global P-value = 0.0057, Bonferroni-Corrected P-value = 0.0684, individual P-value = 0.787 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Lohoff, F. W., 2006 | rs988713 - rs2270641 - rs2270637 - rs1390938 - rs2279709 - rs3735835 - rs1497020 | A-Thr-Thr-Thr-A-G A-Thr-Thr-Thr-A-G | SLC18A1 | P-value = 0.858, OR=...... P-value = 0.858, OR=1, X<sup>2</sup>=0.031 More... | Negative | |
| Lohoff, F. W., 2006 | rs988713 - rs2270641 - rs2270637 - rs1390938 - rs2279709 - rs3735835 - rs1497020 | A-Thr-Thr-Thr-A-C A-Thr-Thr-Thr-A-C | SLC18A1 | P-value = 0.086, OR=...... P-value = 0.086, OR=1.232, X<sup>2</sup>=2.945 More... | Negative | |
| Lohoff, F. W., 2006 | rs988713 - rs2270641 - rs2270637 - rs1390938 - rs2279709 - rs3735835 - rs1497020 | A-Thr-Ser-Thr-C-G A-Thr-Ser-Thr-C-G | SLC18A1 | P-value = 0.43, OR=1...... P-value = 0.43, OR=1.047, X<sup>2</sup>=0.621 More... | Negative | |
| Lohoff, F. W., 2006 | rs988713 - rs2270641 - rs2270637 - rs1390938 - rs2279709 - rs3735835 - rs1497020 | A-Pro-Thr-Thr-C-C A-Pro-Thr-Thr-C-C | SLC18A1 | P-value = 0.442, OR=...... P-value = 0.442, OR=1.022, X<sup>2</sup>=0.589 More... | Negative | |
| Lohoff, F. W., 2006 | rs988713 - rs2270641 - rs2270637 - rs1390938 - rs2279709 - rs3735835 - rs1497020 | G-Thr-Thr-Ile-A-G G-Thr-Thr-Ile-A-G | SLC18A1 | P-value = 0.004, OR=...... P-value = 0.004, OR=0.793, X<sup>2</sup>=8.023 More... | Haplotype analysis s...... Haplotype analysis shows association with a possible protective haplotype for BPD; however, haplotypes do not reach a greater level of statistical significance than the single marker analysis. More... | Positive |
| Schosser, A.,2011 | rs9880989 - rs6605321 | IQCG LMLN | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.775, global P-value = 0.436 More... | No significant asso...... No significant association was found . More... | Negative | |
| Palo, O. M.,2010 | rs987187 - rs923784 | G-G G-G | PGM5 | Haplotypic associati...... Haplotypic association:Z-score=-0.811, FBAT P-value = 0.417 More... | No significant asso...... No significant association was found . More... | Negative |
| Roche, S., 2007 | rs9722 - rs881827 | T-C(BPI)/C-C(BPI&...... T-C(BPI)/C-C(BPI&psychosis) More... | S100B | TDT P-value = 0.329,...... TDT P-value = 0.329, X<sup>2</sup>=3.434 in BPI, TDT P-value = 0.061, X<sup>2</sup>=5.596 in BPI and psychosis More... | Negative | |
| Ohnishi, T., 2007 | rs971362 - IMPA2_-708G>A - rs2075824 - IMPA2_-207T>C - IMPA2_-185A>G | T-A-T-C-G T-A-T-C-G | IMPA2 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.239, OR=0.859, X<sup>2</sup>=1.386 More... | There were no promot...... There were no promoter haplotypes spanning SNP02-SNP06 that were significantly associated with bipolar disorder More... | Negative |
| Ohnishi, T., 2007 | rs971362 - IMPA2_-708G>A - rs2075824 - IMPA2_-207T>C - IMPA2_-185A>G | T-G-T-C-G T-G-T-C-G | IMPA2 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.497, OR=0.936, X<sup>2</sup>=0.462 More... | There were no promot...... There were no promoter haplotypes spanning SNP02-SNP06 that were significantly associated with bipolar disorder More... | Negative |
| Ohnishi, T., 2007 | rs971362 - IMPA2_-708G>A - rs2075824 - IMPA2_-207T>C - IMPA2_-185A>G | G-G-C-T-G G-G-C-T-G | IMPA2 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.725, OR=1.045, X<sup>2</sup>=0.124 More... | There were no promot...... There were no promoter haplotypes spanning SNP02-SNP06 that were significantly associated with bipolar disorder More... | Negative |
| Ohnishi, T., 2007 | rs971362 - IMPA2_-708G>A - rs2075824 - IMPA2_-207T>C - IMPA2_-185A>G | G-G-C-T-A G-G-C-T-A | IMPA2 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.209, OR=1.126, X<sup>2</sup>=1.576 More... | There were no promot...... There were no promoter haplotypes spanning SNP02-SNP06 that were significantly associated with bipolar disorder More... | Negative |
| Ohnishi, T., 2007 | rs971362 - IMPA2_-708G>A - rs2075824 | IMPA2 | P-value = 0.03 P-value = 0.03 | obtained a significa...... obtained a significant empirical p-value for the three-locus window More... | Positive | |
| Ohnishi, T., 2007 | rs971362 - IMPA2_-708G>A | IMPA2 | P-value = 0.022 P-value = 0.022 | displayed evidence o...... displayed evidence of association with bipolar illness More... | Positive | |
| Palo, O. M., 2007 | rs967244 - rs6675281 | G-T G-T | DISC1 | Individual P-value =...... Individual P-value = 0.278 in all, P-value = 0.329 in males, P-value = 0.462 in females; global P-value = 0.576 in all, P-value = 0.449 in males, P-value = 0.673 in females, with bipolar spectrum disorder More... | Negative | |
| Hashimoto, R.,2005(b) | rs960914 - rs2241802 - rs2323019 - rs352203 | FZD3 | Haplotypic associati...... Haplotypic association:global P-values>0.2 More... | No significant asso...... No significant association was found . More... | Negative | |
| Gaysina, D.,2010 | rs9558562 - rs1935062 - rs947267 | DAOA | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=0.89, P-value = 0.64 for UK sample; X<sup>2</sup>=1.65, P-value = 0.44 for Canadian sample. More... | No significant asso...... No significant association was found . More... | Negative | |
| Ross, K. A.,2011 | rs9551988 - (SNP A-1797773) | PSPC1 | SNP interactions:P-v...... SNP interactions:P-value = 0.74 More... | No significant asso...... No significant association was found . More... | Negative | |
| Li, Y.,2010 | rs951436 - rs951439 - rs266131 - rs2842030 | G-G-A-G G-G-A-G | RGS4 | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=2.598, Fisher's P-value = 0.107075, Pearson's P-value = 0.107008, OR(95%CI)=1.66(0.891-3.094) More... | No significant asso...... No significant association was found . More... | Negative |
| Li, Y.,2010 | rs951436 - rs951439 - rs266131 - rs2842030 | G-G-A-T G-G-A-T | RGS4 | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=2.143, Fisher's P-value = 0.143261, Pearson's P-value = 0.143186, OR(95%CI)=1.746(0.821-3.714) More... | No significant asso...... No significant association was found . More... | Negative |
| Li, Y.,2010 | rs951436 - rs951439 - rs266131 - rs2842030 | G-G-G-T G-G-G-T | RGS4 | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=2.249, Fisher's P-value = 0.133748, Pearson's P-value = 0.133674, OR(95%CI)=1.189(0.948-1.491) More... | No significant asso...... No significant association was found . More... | Negative |
| Li, Y.,2010 | rs951436 - rs951439 - rs266131 - rs2842030 | T-A-A-G T-A-A-G | RGS4 | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=5.367, Fisher's P-value = 0.020558, Pearson's P-value = 0.020539, OR(95%CI)=0.764(0.608-0.960) More... | Significant associat...... Significant association was found in BD-II. More... | Positive |
| Li, Y.,2010 | rs951436 - rs951439 - rs266131 - rs2842030 | T-G-A-T T-G-A-T | RGS4 | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=0.651, Fisher's P-value = 0.419848, Pearson's P-value = 0.419814, OR(95%CI)=0.799(0.462-1.380) More... | No significant asso...... No significant association was found . More... | Negative |
| Abou Jamra, R., 2010 | rs9496070 - rs7746181 - rs7754794 - rs9496094 - rs2397690 | GGGAA GGGAA | MCHR2 | P-value = 0.0345 in ...... P-value = 0.0345 in psychotic symptoms sample, P-value = 0.0057 in psychotic symptoms and male sample; global P-value = 0.029 in psychotic symptoms sample, global P-value = 0.0245 in psychotic symptoms and male sample. Not significant in all BPAD sample. More... | haplotype-block II d...... haplotype-block II don't show significance in all BPAD sample, but showed additional evidence of association in psychotic symptoms sample. haplotype GGGAA was more frequent in patients as risk factor. More... | Positive |
| Abou Jamra, R., 2010 | rs9496070 - rs7746181 - rs7754794 - rs9496094 - rs2397690 | GAGGG GAGGG | MCHR2 | P-value = 0.018 in p...... P-value = 0.018 in psychotic symptoms sample, P-value = 0.0415 in psychotic symptoms and male sample; global P-value = 0.029 in psychotic symptoms sample, global P-value = 0.0245 in psychotic symptoms and male sample. Not significant in all BPAD sample. More... | haplotype-block II d...... haplotype-block II don't show significance in all BPAD sample, but showed additional evidence of association in psychotic symptoms sample. haplotype GAGGG was found to be 5% less frequent in patients as protective factor. More... | Positive |
| Pickard, B. S., 2006 | rs949056 - rs949054 - rs602104 - rs2276319 | GRIK4 | P-value = 0.382 betw...... P-value = 0.382 between SCZ cases and controls; P-value = 0.91 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs949056 - rs949054 - rs602104 - rs2276319 | A-T-C-A A-T-C-A | GRIK4 | P-value = 0.0098 P-value = 0.0098 | Positive | |
| Pickard, B. S., 2006 | rs949056 - rs949054 - rs602104 | GRIK4 | P-value = 0.054 betw...... P-value = 0.054 between BPD cases and controls; P-value = 0.364 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs949056 - rs949054 - rs602104 | A-T-C A-T-C | GRIK4 | P-value = 0.0043 P-value = 0.0043 | Positive | |
| Pickard, B. S., 2006 | rs949056 - rs949054 | GRIK4 | P-value = 0.317 betw...... P-value = 0.317 between BPD cases and controls; P-value = 0.767 between all cases and controls More... | Positive | ||
| Iwayama, Y., 2010 | rs9490550 - rs9401596 | TG TG | FABP7 | P-value = 0.057, glo...... P-value = 0.057, global P-value = 0.0352, Permutation global P-value = 0.0332 More... | Negative | |
| Iwayama, Y., 2010 | rs9490550 - rs9401596 | GA GA | FABP7 | P-value = 0.313, glo...... P-value = 0.313, global P-value = 0.0352, Permutation global P-value = 0.0332 More... | Negative | |
| Iwayama, Y., 2010 | rs9490550 - rs9401596 | GG GG | FABP7 | P-value = 0.012, glo...... P-value = 0.012, global P-value = 0.0352, Permutation global P-value = 0.0332, OR(95% CI)=1.18(1.04-1.35). More... | is over-represented ...... is over-represented in the disease group and even after correction for multiple testing by permutation tests. More... | Positive |
| Pickard, B. S., 2006 | rs949054 - rs602104 - rs2276319 - rs513548 | GRIK4 | P-value = 0.222 betw...... P-value = 0.222 between SCZ cases and controls; P-value = 0.566 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs949054 - rs602104 - rs2276319 | GRIK4 | P-value = 0.124 betw...... P-value = 0.124 between BPD cases and controls; P-value = 0.589 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs949054 - rs602104 - rs2276319 | T-C-A T-C-A | GRIK4 | P-value = 0.0071 P-value = 0.0071 | Positive | |
| Pickard, B. S., 2006 | rs949054 - rs602104 | GRIK4 | P-value = 0.007 betw...... P-value = 0.007 between BPD cases and controls; P-value = 0.093 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs949054 - rs602104 | T-C T-C | GRIK4 | P-value = 0.0028 P-value = 0.0028 | Positive | |
| Pickard, B. S., 2006 | rs948028 - rs2852217 - rs879602 - rs1954787 | GRIK4 | P-value = 0.009 betw...... P-value = 0.009 between SCZ cases and controls; P-value = 0.005 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs948028 - rs2852217 - rs879602 | GRIK4 | P-value = 0.011 betw...... P-value = 0.011 between BPD cases and controls; P-value = 0.158 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs948028 - rs2852217 | GRIK4 | P-value = 0.309 betw...... P-value = 0.309 between BPD cases and controls; P-value = 0.383 between all cases and controls More... | Negative | ||
| Gaysina, D.,2010 | rs947267 - rs778292 - rs3918342 | DAOA | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=3.44, P-value = 0.75 for UK sample; X<sup>2</sup>=4.21, P-value = 0.76 for Canadian sample. More... | No significant asso...... No significant association was found . More... | Negative | |
| Palo, O. M.,2010 | rs944700 - rs1359885 | G-C G-C | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-1.585, FBAT P-value = 0.113 More... | No significant asso...... No significant association was found . More... | Negative |
| Liu, C., 2007 | rs9389008 - rs4628126 - rs4320395 - rs12189813 | TAAR4P | P-value = 0.0063, P-...... P-value = 0.0063, P-value = 0.13 in the second set sample (Waves 3-4 & CHIP); P-value = 0.015 in combined data More... | One distal haplotype...... One distal haplotype in the TAAR4 gene showed nominal association with BD More... | Positive | |
| Roche, S., 2007 | rs933151 - rs8129542 | TRPM2 | TDT P-value = 0.717,...... TDT P-value = 0.717, X<sup>2</sup>=1.352 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| Zeng, Z.,2011 | rs9315885 - rs9532988 - rs1012053 | C-A-A C-A-A | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.00000387, permutated P-value = 0 for BPD; P-value = 0.0000259, permutated P-value = 0.0001 for BPDI More... | Significant associat...... Significant association was found in both BPD and BPDI. More... | Positive |
| Zeng, Z.,2011 | rs9315885 - rs9532988 - rs1012053 | C-A-C C-A-C | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.003, permutated P-value = 0.018 for BPD; P-value = 0.002, permutated P-value = 0.015 for BPDI More... | Significant associat...... Significant association was found in both BPD and BPDI. More... | Positive |
| Zeng, Z.,2011 | rs9315885 - rs9532988 - rs1012053 | T-A-A T-A-A | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.233, permutated P-value = 0.911 for BPD; P-value = 0.571, permutated P-value = 1 for BPDI More... | No significant asso...... No significant association was found . More... | Negative |
| Zeng, Z.,2011 | rs9315885 - rs9532988 - rs1012053 | T-G-A T-G-A | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.316, permutated P-value = 0.968 for BPD; P-value = 0.45, permutated P-value = 0.996 for BPDI More... | No significant asso...... No significant association was found . More... | Negative |
| Squassina, A.,2009 | rs9315885 - rs1012053 - rs1170191 | C-A-C C-A-C | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.029, permutation P-value = 0.121 More... | No significant asso...... No significant association was found . More... | Negative |
| Squassina, A.,2009 | rs9315885 - rs1012053 - rs1170191 | C-C-A C-C-A | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.038, permutation P-value = 0.244 More... | No significant asso...... No significant association was found . More... | Negative |
| Squassina, A.,2009 | rs9315885 - rs1012053 - rs1170191 | T-A-A T-A-A | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.024, permutation P-value = 0.11 More... | No significant asso...... No significant association was found . More... | Negative |
| Squassina, A.,2009 | rs9315885 - rs1012053 - rs1170191 | T-A-C T-A-C | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.006, permutation P-value = 0.025 More... | Significant associat...... Significant association was found. More... | Positive |
| Shi, J., 2007 | rs9314347 - rs891397 | G-C G-C | CHRNA2 | Uncorrected P-value ...... Uncorrected P-value = 0.029, Gene-wide Permutation P-value = 0.349 More... | The haplotype showed...... The haplotype showed nominally significant association with BD by Haploview analyses but the significance did not remain after permutation testing More... | Positive |
| Lohoff, F. W., 2008 (a) | rs928978 - rs2231187 - rs1610037 | 1-1-1 (1=major alle...... 1-1-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1, X<sup>2&...... OR=1, X<sup>2</sup>=1.38, P-value =0.24 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs928978 - rs2231187 - rs1610037 | 1-1-2 (1=major alle...... 1-1-2 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1.75, X<sup>...... OR=1.75, X<sup>2</sup>=0.44, P-value =0.503 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs928978 - rs2231187 - rs1610037 | 1-2-1 (1=major alle...... 1-2-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1.33, X<sup>...... OR=1.33, X<sup>2</sup>=0.23, P-value =0.626 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs928978 - rs2231187 - rs1610037 | 2-1-1 (1=major alle...... 2-1-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1.3, X<sup>...... OR=1.3, X<sup>2</sup>=0.1, P-value =0.746 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs928978 - rs2231187 - rs1610037 | 2-1-2 (1=major alle...... 2-1-2 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1.25, X<sup>...... OR=1.25, X<sup>2</sup>=0.01, P-value =0.917 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Severinsen, J. E., 2006 (b) | rs916005 - rs715519 - rs2272843 - rs3810971 | MAPK8IP2 MOV10L1 | P-value = 0.3167 in ...... P-value = 0.3167 in BD, P-value = 0.7152 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs916005 - rs715519 - rs2272843 | MAPK8IP2 MOV10L1 | P-value = 0.8328 in ...... P-value = 0.8328 in BD, P-value = 0.9786 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs916005 - rs715519 | MAPK8IP2 | P-value = 0.8895 in ...... P-value = 0.8895 in BD, P-value = 0.9552 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (a) | rs909669 - D22S279 - rs133068 - rs133069 - rs133070 | C-7-C-C-A C-7-C-C-A | MCHR1 ADSL | CLUMP P-value = 0.11...... CLUMP P-value = 0.1179 in BPD, P-value = 0.0006 in BPD and SZ; risk haplotype More... | Positive | |
| Severinsen, J. E., 2006 (a) | rs909669 - D22S279 - rs133068 - rs133069 - rs133070 | C-6-C-C-A C-6-C-C-A | MCHR1 ADSL | CLUMP P-value = 0.04...... CLUMP P-value = 0.0406 in BPD, P-value = 0.3176 in BPD and SZ; risk haplotype More... | Positive | |
| Severinsen, J. E., 2006 (a) | rs909669 - D22S279 - rs133068 - rs133069 - rs133070 | C-6/7-C-C-A C-6/7-C-C-A | MCHR1 ADSL | CLUMP P-value = 0.00...... CLUMP P-value = 0.0026 in BPD, P-value = 7E-05 in BPD and SZ; risk haplotype More... | Positive | |
| Kakiuchi, C., 2007 (b) | rs882565 - rs4821907 - rs1028321 | ATF4 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.287 in Japanese samples; TDT P-value = 0.4214 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Kakiuchi, C., 2007 (b) | rs882565 - rs4821907 | ATF4 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.5575 in Japanese samples; TDT P-value = 0.404 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Roche, S., 2007 | rs881827 - rs2839355 | C-T(BPI)/T-C(BPI&...... C-T(BPI)/T-C(BPI&psychosis) More... | S100B | TDT P-value = 0.345,...... TDT P-value = 0.345, X<sup>2</sup>=3.319 in BPI, TDT P-value = 0.63, X<sup>2</sup>=0.925 in BPI and psychosis More... | Negative | |
| Pickard, B. S., 2006 | rs879602 - rs1954787 - rs4935752 - rs6589846 | GRIK4 | P-value = 0.652 betw...... P-value = 0.652 between SCZ cases and controls; P-value = 0.176 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs879602 - rs1954787 - rs4935752 | GRIK4 | P-value = 0.892 betw...... P-value = 0.892 between BPD cases and controls; P-value = 0.449 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs879602 - rs1954787 | GRIK4 | P-value = 0.885 betw...... P-value = 0.885 between BPD cases and controls; P-value = 0.949 between all cases and controls More... | Negative | ||
| Lundorf, M. D.,2005 | rs872123 - rs3749034 - rs769404 | GAD1 | Haplotypic associati...... Haplotypic association:in the Danish sample set, P-value = 0.049 for BPAD More... | Significant associat...... Significant association was found in the Danish sample set. More... | Positive | |
| Lundorf, M. D.,2005 | rs872123 - rs3749034 | GAD1 | Haplotypic associati...... Haplotypic association:in the Danish sample set, P-value = 0.031 for BPAD. More... | Significant associat...... Significant association was found in the Danish sample set. More... | Positive | |
| Lohoff, F. W., 2010 | rs871044 - rs3974590 - rs593713 - rs602201 | GGAT GGAT | MPPE1 | Chi square=0.79, P-v...... Chi square=0.79, P-value = 0.374, permutation P-value = 0.962 More... | Haplotype analysis o...... Haplotype analysis of all four SNP configurations did not reveal an association with BPD. More... | Negative |
| Lohoff, F. W., 2010 | rs871044 - rs3974590 - rs593713 - rs602201 | AGAT AGAT | MPPE1 | Chi square=0.761, P-...... Chi square=0.761, P-value = 0.383, permutation P-value = 0.966 More... | Haplotype analysis o...... Haplotype analysis of all four SNP configurations did not reveal an association with BPD. More... | Negative |
| Lohoff, F. W., 2010 | rs871044 - rs3974590 - rs593713 - rs602201 | GGAA GGAA | MPPE1 | Chi square=0.533, P-...... Chi square=0.533, P-value = 0.465, permutation P-value = 0.991 More... | Haplotype analysis o...... Haplotype analysis of all four SNP configurations did not reveal an association with BPD. More... | Negative |
| Lohoff, F. W., 2010 | rs871044 - rs3974590 - rs593713 - rs602201 | GAGA GAGA | MPPE1 | Chi square=0.131, P-...... Chi square=0.131, P-value = 0.717, permutation P-value = 1 More... | Haplotype analysis o...... Haplotype analysis of all four SNP configurations did not reveal an association with BPD. More... | Negative |
| Lohoff, F. W., 2010 | rs871044 - rs3974590 - rs593713 - rs602201 | AAGT AAGT | MPPE1 | Chi square=2.495, P-...... Chi square=2.495, P-value = 0.114, permutation P-value = 0.503 More... | Haplotype analysis o...... Haplotype analysis of all four SNP configurations did not reveal an association with BPD. More... | Negative |
| Lohoff, F. W., 2010 | rs871044 - rs3974590 - rs593713 - rs602201 | AAGA AAGA | MPPE1 | Chi square=0.415, P-...... Chi square=0.415, P-value = 0.52, permutation P-value = 0.997 More... | Haplotype analysis o...... Haplotype analysis of all four SNP configurations did not reveal an association with BPD. More... | Negative |
| Lohoff, F. W., 2010 | rs871044 - rs3974590 - rs593713 - rs602201 | AGAA AGAA | MPPE1 | Chi square=0.68, P-v...... Chi square=0.68, P-value = 0.41, permutation P-value = 0.977 More... | Haplotype analysis o...... Haplotype analysis of all four SNP configurations did not reveal an association with BPD. More... | Negative |
| Lohoff, F. W., 2010 | rs871044 - rs3974590 - rs593713 - rs602201 | GAGT GAGT | MPPE1 | Chi square=0.651, P-...... Chi square=0.651, P-value = 0.42, permutation P-value = 0.981 More... | Haplotype analysis o...... Haplotype analysis of all four SNP configurations did not reveal an association with BPD. More... | Negative |
| Lohoff, F. W., 2010 | rs871044 - rs3974590 - rs593713 - rs602201 | GAAT GAAT | MPPE1 | Chi square=2.786, P-...... Chi square=2.786, P-value = 0.095, permutation P-value = 0.431 More... | Haplotype analysis o...... Haplotype analysis of all four SNP configurations did not reveal an association with BPD. More... | Negative |
| Kakiuchi, C., 2007 (b) | rs8647 - rs8667 | ATF5 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.3635 in Japanese samples; TDT P-value = 0.8887 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Palo, O. M.,2010 | rs846427 - rs868053 | A-G A-G | CPED1 | Haplotypic associati...... Haplotypic association:Z-score=-1.368, FBAT P-value = 0.171 More... | No significant asso...... No significant association was found . More... | Negative |
| Schosser, A.,2011 | rs823512 - rs11475 | A-C A-C | PPP1R2 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.035, global P-value = 0.056 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Palo, O. M., 2007 | rs821616 - rs1411771 - rs980989 | T-T-G T-T-G | DISC1 | Individual P-value =...... Individual P-value = 0.0001 in all, P-value = 0.005 in males, P-value = 0.021 in females; global P-value = 0.021 in all, P-value = 0.115 in males, P-value = 0.214 in females, with bipolar spectrum disorder More... | An extended allelic ...... An extended allelic haplotype including rs821616, rs1411771 and in addition rs980898, was also under-transmitted to affected males and females More... | Positive |
| Palo, O. M., 2007 | rs821616 - rs1411771 | T-T T-T | DISC1 | Individual P-value =...... Individual P-value = 0.0002 in all, P-value = 0.011 in males, P-value = 0.016 in females; global P-value = 0.004 in all, P-value = 0.07 in males, P-value = 0.092 in females, with bipolar spectrum disorder More... | the haplotype at the...... the haplotype at the 3' end of DISC1, composed of SNPs rs821616 and rs1411771, was under-transmitted to affected females and males More... | Positive |
| Xiao, Y.,2011 | rs821597 - rs821653 | A-A A-A | DISC1 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.9924 More... | No significant asso...... No significant association was found . More... | Negative |
| Lohoff, F. W., 2008 (a) | rs8192595 - rs2856966 - rs928978 | 1-1-1 (1=major alle...... 1-1-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1, X<sup>2&...... OR=1, X<sup>2</sup>=0.48, P-value =0.487 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs8192595 - rs2856966 - rs928978 | 1-1-2 (1=major alle...... 1-1-2 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1.14, X<sup>...... OR=1.14, X<sup>2</sup>=0.23, P-value =0.625 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs8192595 - rs2856966 - rs928978 | 1-2-2 (1=major alle...... 1-2-2 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=0.65, X<sup>...... OR=0.65, X<sup>2</sup>=1.96, P-value =0.161 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Roche, S., 2007 | rs8129542 - rs2238724 | TRPM2 | TDT P-value = 0.251,...... TDT P-value = 0.251, X<sup>2</sup>=2.762 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| Ferraren, D. O.,2005 | rs8054 - rs1047740 - rs2181675 - rs1571069 - rs2274389 - rs1408047 - rs2281886 - rs2281885 - rs4743 - rs2296147 | TEX30 | Haplotypic associati...... Haplotypic association:TDT: Global P-value = 0.013 in CNG family series; Global P-value = 0.6 in NIMH genetic initiative pedigrees More... | Significant associat...... Significant association was found in CNG family series. More... | Positive | |
| Shi, J., 2007 | rs8035668 - rs1500946 | C-A C-A | CHRNA7 | Uncorrected P-value ...... Uncorrected P-value = 0.03, Gene-wide Permutation P-value = 0.554 More... | The haplotype showed...... The haplotype showed nominally significant association with BD by Haploview analyses but the significance did not remain after permutation testing More... | Positive |
| Kishi, T.,2012(b) | rs8007267 - rs378364 - rs841 | C-T-C C-T-C | GCH1 | Global P-value = 0.6...... Global P-value = 0.605,OR(95%CI) = 1.00(1.00-1.00),individual P-value = 0.623 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Kishi, T.,2012(b) | rs8007267 - rs378364 - rs841 | C-T-T C-T-T | GCH1 | Global P-value = 0.6...... Global P-value = 0.605,OR(95%CI) = 1.03(0.869-1.15),P-value = 0.822 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Kishi, T.,2012(b) | rs8007267 - rs378364 - rs841 | T-A-C T-A-C | GCH1 | Global P-value = 0.6...... Global P-value = 0.605,OR(95%CI) = 1.06(0.893-1.08),P-value = 0.899 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Campos, S. B., 2010 | rs7955501 - rs10506645 - rs4760820 | ATC ATC | TPH2 | P-value = 0.05, OR =...... P-value = 0.05, OR = 4.117 More... | The A-T-C haplotype ...... The A-T-C haplotype was significantly more frequent in patients with BD when compared with controls, but the result did not survive permutation testing. More... | Positive |
| Pickard, B. S., 2006 | rs7928347 - rs2000869 - rs7479743 - rs6589832 | GRIK4 | P-value = 0.601 betw...... P-value = 0.601 between SCZ cases and controls; P-value = 0.306 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs7928347 - rs2000869 - rs7479743 | GRIK4 | P-value = 0.486 betw...... P-value = 0.486 between BPD cases and controls; P-value = 0.43 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs7928347 - rs2000869 | GRIK4 | P-value = 0.559 betw...... P-value = 0.559 between BPD cases and controls; P-value = 0.583 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs7925270 - rs3133855 - rs3133226 - rs2187495 | GRIK4 | P-value = 0.544 betw...... P-value = 0.544 between SCZ cases and controls; P-value = 0.86 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs7925270 - rs3133855 - rs3133226 | GRIK4 | P-value = 0.795 betw...... P-value = 0.795 between BPD cases and controls; P-value = 0.876 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs7925270 - rs3133855 | GRIK4 | P-value = 0.768 betw...... P-value = 0.768 between BPD cases and controls; P-value = 0.95 between all cases and controls More... | Negative | ||
| Cuellar-Barboza, A. B., 2016 | rs7895307 - rs12772424 | G-T G-T | TCF7L2 | P-value=0.0008 P-value=0.0008 | Haplotype analysis o...... Haplotype analysis of the two SNPs with strongest evidence for association with BD via BMI interaction in the sample analyzed in the present study and the GAIN data demonstrated that the rs7895307 G-rs12772424 T haplotype is associated with a greater risk for BD as BMI increases. More... | |
| Zhang, Z.,2009(a) | rs778294 - rs778293 | G-A G-A | DAOA | Haplotypic associati...... Haplotypic association:P-value = 6.0E-04 More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhang, Z.,2009(a) | rs778294 - rs778293 | G-G G-G | DAOA | Haplotypic associati...... Haplotypic association:P-value = 0.022 More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhang, Z.,2009(a) | rs778293 - rs3918342 | A-A A-A | DAOA | Haplotypic associati...... Haplotypic association:P-value = 0.67 More... | No significant asso...... No significant association was found . More... | Negative |
| Zhang, Z.,2009(a) | rs778293 - rs3918342 | A-G A-G | DAOA | Haplotypic associati...... Haplotypic association:P-value = 0.01 More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhang, Z.,2009(a) | rs778293 - rs3918342 | G-G G-G | DAOA | Haplotypic associati...... Haplotypic association:P-value = 0.064 More... | No significant asso...... No significant association was found . More... | Negative |
| Gaysina, D.,2010 | rs778292 - rs3918342 - rs1421292 | DAOA | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=2.87, P-value = 0.41 for UK sample; X<sup>2</sup>=2.87, P-value = 0.41 for Canadian sample. More... | No significant asso...... No significant association was found . More... | Negative | |
| Kim, S. H., 2012 (a) | rs769700 - rs704076 - rs770087 - rs808820 - rs2279574 | T-G-T-A-T T-G-T-A-T | DUSP6 | P-value = 0.0139, X&...... P-value = 0.0139, X<sup>2</sup>=6.0530, OR=0.6971 More... | the T-G-T-A-T haplot...... the T-G-T-A-T haplotype was significantly under-represented in female patients with BD, but did not show positive associations with BD among men. More... | Positive |
| Kim, S. H., 2012 (a) | rs769700 - rs704076 - rs770087 - rs808820 - rs2279574 | T-G-T-A-G T-G-T-A-G | DUSP6 | P-value = 0.4260, X&...... P-value = 0.4260, X<sup>2</sup>=0.6340, OR=1.1240 More... | no significant assoc...... no significant association was reported in this study More... | Negative |
| Kim, S. H., 2012 (a) | rs769700 - rs704076 - rs770087 - rs808820 - rs2279574 | C-T-G-G-G C-T-G-G-G | DUSP6 | P-value = 0.0157, X&...... P-value = 0.0157, X<sup>2</sup>=5.8330, OR=3.2415 More... | the C-T-G-G-G haplot...... the C-T-G-G-G haplotype of DUSP6 was significantly over-represented in female patients with BD, but did not show positive associations with BD among men. More... | Positive |
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | G-G-G-C-A-G-G-A G-G-G-C-A-G-G-A | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.463,Z = 1.096,P-value = 0.273,P-2side = 0.283 More... | ||
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | A-A-A-G-G-A-A-G A-A-A-G-G-A-A-G | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.255,Z = 0.448,P-value = 0.654,P-2side = 0.651 More... | ||
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | G-G-G-C-G-G-G-G G-G-G-C-G-G-G-G | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.102,Z = 1.128,P-value = 0.259,P-2side = 0.29 More... | ||
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | G-G-G-C-G-G-G-A G-G-G-C-G-G-G-A | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.093,Z = -2.893,P-value = 0.004,P-2side = 0.004 More... | Association with BD ...... Association with BD was observed in the family study More... | Positive |
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | G-G-G-C-G-A-G-G G-G-G-C-G-A-G-G | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.023,Z = 0.124,P-value = 0.902,P-2side = 0.837 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | A-A-A-G-G-G-A-G A-A-A-G-G-G-A-G | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.017,Z = 0.087,P-value = 0.931,P-2side = 0.977 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | G-G-G-C-A-G-G-G G-G-G-C-A-G-G-G | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.012,Z = -1.35,P-value = 0.177,P-2side = 0.269 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | G-G-G-C-G-A-G-A G-G-G-C-G-A-G-A | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.008,Z = -2.291,P-value = 0.022,P-2side = 0.009 More... | Association with BD ...... Association with BD was observed in the family study More... | Positive |
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | A-A-A-G-G-G-G-G A-A-A-G-G-G-G-G | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.008,Z = 0.499,P-value = 0.618,P-2side = 0.644 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | G-G-G-C-G-G-A-G G-G-G-C-G-G-A-G | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.004,Z = 0.063,P-value = 0.95,P-2side = 0.952 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | A-A-A-G-G-A-A-A A-A-A-G-G-A-A-A | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.003,Z = -0.46,P-value = 0.646,P-2side = 0.895 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | G-G-G-C-A-A-G-A G-G-G-C-A-A-G-A | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.002,Z = 1.414,P-value = 0.157,P-2side = 0.248 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | A-A-A-G-A-G-G-A A-A-A-G-A-G-G-A | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.002,Z = -2.601,P-value = 0.009,P-2side = 0.028 More... | Association with BD ...... Association with BD was observed in the family study More... | Positive |
| Gonzalez, S.,2013 | rs769087 - rs1006737 - rs2159100 - rs4765905 - rs2370413 - rs7297582 - rs758170 - rs1860002 | G-A-A-G-G-A-A-G G-A-A-G-G-A-A-G | CACNA1C | Haplotype analysis:W...... Haplotype analysis:Whole marker permutation test P-value = 0.0018,frequency is0.002,Z = 2.236,P-value = 0.025,P-2side = 0.031 More... | Association with BD ...... Association with BD was observed in the family study More... | Positive |
| Ram Murthy, A., 2012 | rs766288 - rs821616 | C-A C-A | TSNAX DISC1 | P-value=0.024 for BP...... P-value=0.024 for BPAD, P-value=0.019 for combined cases, P-value=0.014 for BPAD females, P-value=0.004 for combined females, P-value=0.413 for BPAD males, P-value=0.589 for combined males More... | Allelic combination ...... Allelic combination C-A (P=0.004) in the female cases with combined phenotype showed significant association when multiple corrections were performed for all tests within each stratified gender (combined, females, males). More... | Positive |
| Ram Murthy, A., 2012 | rs766288 - rs821616 | A-A A-A | TSNAX DISC1 | P-value=0.667 for BP...... P-value=0.667 for BPAD, P-value=0.831 for combined cases, P-value=0.032 for BPAD females, P-value=0.022 for combined females, P-value=0.187 for BPAD males, P-value=0.028 for combined males More... | Few additional combi...... Few additional combinations that were found to be significantly associated after multiple corrections (n=12) were A-T in BPAD females (P=0.012, protective combination); C-A (P=0.014, risk combination), C-A in SCZ females (P=0.011, risk combination), A-T in combined female cases (P=0.012, protective combination) and A-A in combined female cases (P=0.022, protective combination) compared with control females. However nominal significance observed in BPAD (C-A, P=0.024, risk combination), cases with the combined phenotype (C-A, P=0.019, risk combination), SCZ males (A-A, P=0.016, risk combination) and males with the combined phenotype (A-A, P=0.028, risk combination), which did not withstand the multiple corrections. More... | Positive |
| Ram Murthy, A., 2012 | rs766288 - rs821616 | C-T C-T | TSNAX DISC1 | P-value=0.316 for BP...... P-value=0.316 for BPAD, P-value=0.115 for combined cases, P-value=0.835 for BPAD females, P-value=0.489 for combined females, P-value=0.244 for BPAD males, P-value=0.177 for combined males More... | Negative | |
| Ram Murthy, A., 2012 | rs766288 - rs821616 | A-T A-T | TSNAX DISC1 | P-value=0.114 for BP...... P-value=0.114 for BPAD, P-value=0.215 for combined cases, P-value=0.012 for BPAD females, P-value=0.012 for combined females, P-value=0.875 for BPAD males, P-value=0.606 for combined males More... | Few additional combi...... Few additional combinations that were found to be significantly associated after multiple corrections (n=12) were A-T in BPAD females (P=0.012, protective combination); C-A (P=0.014, risk combination), C-A in SCZ females (P=0.011, risk combination), A-T in combined female cases (P=0.012, protective combination) and A-A in combined female cases (P=0.022, protective combination) compared with control females. However nominal significance observed in BPAD (C-A, P=0.024, risk combination), cases with the combined phenotype (C-A, P=0.019, risk combination), SCZ males (A-A, P=0.016, risk combination) and males with the combined phenotype (A-A, P=0.028, risk combination), which did not withstand the multiple corrections. More... | Positive |
| Ram Murthy, A., 2012 | rs766288 - rs3738401 - rs2812393 - rs821616 | C-G-G-T C-G-G-T | TSNAX DISC1 | P-value=0.028 for BP...... P-value=0.028 for BPAD, P-value=0.074 for BPAD&SZ More... | C-G-G-T haplotype sh...... C-G-G-T haplotype showed relatively lesser frequency in BPAD (P=0.028), SCZ (P=0.0189) and combined cases of BPAD or SCZ (P=0.0065) and combined males of BPAD or SCZ (P=0.0205) compared with controls. More... | Positive |
| Ram Murthy, A., 2012 | rs766288 - rs3738401 - rs2812393 - rs821616 | A-G-G-T A-G-G-T | TSNAX DISC1 | P-value=0.0273 for B...... P-value=0.0273 for BPAD females, P-value=0.0469 for BPAD&SZ, P-value=0.0209 for BPAD females &SCZ females More... | Haplotype A-G-G-T wa...... Haplotype A-G-G-T was also underrepresented in combined cases of BPAD or SCZ (P=0.0469), BPAD females (P=0.0273) and pooled females of BPAD or SCZ (P=0.0209). More... | Positive |
| Ram Murthy, A., 2012 | rs766288 - rs2812393 | C-C C-C | TSNAX DISC1 | P-value=0.009 for BP...... P-value=0.009 for BPAD, P-value=0.016 for combined cases, P-value=0.003 for BPAD females, P-value=0.001 for combined females, P-value=0.414 for BPAD males, P-value=0.703 for combined males More... | Analyses of these tw...... Analyses of these two SNPs showed significant associations with allelic combination C-C (P=0.009) in the BPAD phenotype when multiple corrections were performed for all tests within each stratified gender (combined, females, males). More... | Positive |
| Ram Murthy, A., 2012 | rs766288 - rs2812393 | A-G A-G | TSNAX DISC1 | P-value=0.412 for BP...... P-value=0.412 for BPAD, P-value=0.551 for combined cases, P-value=0.598 for BPAD females, P-value=0.013 for combined females, P-value=0.057 for BPAD males, P-value=0.212 for combined males More... | Other combinations i...... Other combinations in BPAD females (C-C, P=0.003, risk combination) and SCZ females (C-C, P=0.011, risk combination; A-G, P=0.016, protective combination), combined female cases (A-G, P=0.013, protective combination; C-C, P=0.001, risk combination) were found to be significantly associated after FDR corrections. More... | Positive |
| Ram Murthy, A., 2012 | rs766288 - rs2812393 | C-G C-G | TSNAX DISC1 | P-value=0.979 for BP...... P-value=0.979 for BPAD, P-value=0.703 for combined cases, P-value=0.717 for BPAD females, P-value=0.969 for combined females, P-value=0.764 for BPAD males, P-value=0.672 for combined males More... | Negative | |
| Ram Murthy, A., 2012 | rs766288 - rs2812393 | A-C A-C | TSNAX DISC1 | P-value=0.897 for BP...... P-value=0.897 for BPAD, P-value=0.632 for combined cases, P-value=0.161 for BPAD females, P-value=0.216 for combined females, P-value=0.299 for BPAD males, P-value=0.099 for combined males More... | Negative | |
| Schosser, A., 2010 | rs766288 - rs2492367 - rs6675281 | ACC ACC | DISC1 | Individual P-value =...... Individual P-value = 0.007, global P-value = 0.19 More... | Positive | |
| Schosser, A., 2010 | rs766288 - rs2492367 | AC AC | TSNAX DISC1 | Individual P-value =...... Individual P-value = 0.004, global P-value = 0.019 More... | showed global haplot...... showed global haplotype associations. Individual haplotype analyses showed that the A-C haplotypes of these two-marker combinations were under-represented in BD. More... | Positive |
| Schosser, A.,2011 | rs7639752 - rs6785339 | PCYT1A TM4SF19 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.427, global P-value = 0.166 More... | No significant asso...... No significant association was found . More... | Negative | |
| Breen, G., 2006 | rs760761 - rs2005976 - rs2619528 | C-G-G C-G-G | DTNBP1 | P-value = 0.03, Z=-2...... P-value = 0.03, Z=-2.19 More... | It is one of the mos...... It is one of the most significant 3-marker haplotypes and empirical p values. More... | Positive |
| Breen, G., 2006 | rs760761 - rs2005976 - rs2619528 | T-A-A T-A-A | DTNBP1 | P-value = 0.05, Z=1....... P-value = 0.05, Z=1.63 More... | It is one of the mos...... It is one of the most significant 3-marker haplotypes and empirical p values. More... | Positive |
| Schosser, A., 2010 | rs7546310 - rs821597 | AT AT | DISC1 | Individual P-value =...... Individual P-value = 0.03, global P-value = 0.05 More... | showed an associatio...... showed an association with BD. Individual haplotype analyses showed that this A-T haplotype was over-represented in BD. More... | Positive |
| Palo, O. M., 2007 | rs751229 - rs3738401 | T-A T-A | DISC1 | Individual P-value =...... Individual P-value = 0.159 in all, P-value = 0.146 in males, P-value = 0.682 in females; global P-value = 0.274 in all, P-value = 0.563 in males, P-value = 0.404 in females, with bipolar spectrum disorder More... | Negative | |
| Prata, D., 2008 | rs746187 - rs3916972 | DAOA | Global X<sup>2...... Global X<sup>2</sup>=6.64, df=3, P-value = 0.05. More... | We found haplotype w...... We found haplotype wise associations with bipolar disorder for both genes. These included a two-SNP haplotype in DAO and a two- SNPhaplotype forDAOA. More... | Positive | |
| Prata, D., 2008 | rs746187 - rs3916972 | 1-1: G-G 1-1: G-G | DAOA | Z-score=2.81, P-valu...... Z-score=2.81, P-value = 0.005 More... | We found haplotype w...... We found haplotype wise associations with bipolar disorder for both genes. These included a two-SNP haplotype in DAO and a two- SNPhaplotype forDAOA. More... | Positive |
| Schosser, A.,2011 | rs745497-rs9881504 | TNK2 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.199, global P-value = 0.068 More... | No significant asso...... No significant association was found . More... | Negative | |
| Nissen, S.,2012 | rs738518 - rs2009667 - rs3484 - rs736720 - rs2284026 | G-G-A-G-G G-G-A-G-G | IFT27, PVALB | TDT:T = 91.38,U = 49...... TDT:T = 91.38,U = 49.81,chi square = 12.23,P-value = 0.000469 for Family phase 1 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Shifman, S., 2004 | rs737865 - rs165688 - rs165599 | G-G-G G-G-G | COMT | P-value = 0.12 in th...... P-value = 0.12 in the total control, P-value = 0.41 in the new control of male, P-value = 0.024 in the total control, P-value = 0.15 in the new control of female, P-value = 0.013 in the total control, P-value = 0.18 in the new control of all; OR (95% CI)=1.21 (0.88-1.67) of male, OR (95% CI)=1.39 (1.00-1.92) of female More... | significantly associ...... significantly associated with bipolar disorder only in women More... | Positive |
| Shifman, S., 2004 | rs737865 - rs165599 | G-G G-G | COMT | P-value = 0.12 in th...... P-value = 0.12 in the total control, P-value = 0.29 in the new control of male, P-value = 0.0037 in the total control, P-value = 0.048 in the new control of female, P-value = 0.0035 in the total control, P-value = 0.061 in the new control of all; OR (95% CI)=1.20 (0.88-1.64) of male, OR (95% CI)=1.53 (1.12-2.09)of female More... | significantly associ...... significantly associated with bipolar disorder only in women More... | Positive |
| Xu, C., 2006 | rs734336 - rs2838556 - rs1785437 - rs1618355 - rs1612472 - rs933151 - rs749909 | T-T-T-C-T-T-A T-T-T-C-T-T-A | TRPM2 | COCAPHASE P-value = ...... COCAPHASE P-value = 2.3E-12, X<sup>2</sup>=49.24; Global P-value of 1.5E-17 (1.05E-16 after correcting for multiple testing) More... | A number of suscepti...... A number of susceptible haplotypes were detected: the T-T-T-C-T-T-A haplotype is one among these showing greatest statistical significance with a frequency of 12.0% in the BD cohort and 0.9% in controls. More... | Positive |
| Xu, C., 2006 | rs734336 - rs2838556 - rs1785437 - rs1618355 - rs1612472 - rs933151 - rs749909 | T-T-T-C-T-T-G T-T-T-C-T-T-G | TRPM2 | COCAPHASE P-value = ...... COCAPHASE P-value = 1.5E-03 , X<sup>2</sup>=14.39; Global P-value of 1.5E-17 (1.05E-16 after correcting for multiple testing) More... | A number of suscepti...... A number of susceptible haplotypes were detected More... | Positive |
| Xu, C., 2006 | rs734336 - rs2838556 - rs1785437 - rs1618355 - rs1612472 - rs933151 - rs749909 | C-C-C-G-C-C-A C-C-C-G-C-C-A | TRPM2 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.01, X<sup>2</sup>=6.57; Global P-value of 1.5E-17 (1.05E-16 after correcting for multiple testing) More... | A number of suscepti...... A number of susceptible haplotypes were detected More... | Positive |
| Xu, C., 2006 | rs734336 - rs2838556 - rs1785437 - rs1618355 - rs1612472 - rs933151 - rs749909 | T-T-T-A-C-T-A T-T-T-A-C-T-A | TRPM2 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.047, X<sup>2</sup>=3.94; Global P-value of 1.5E-17 (1.05E-16 after correcting for multiple testing) More... | A number of suscepti...... A number of susceptible haplotypes were detected More... | Positive |
| Xu, C., 2006 | rs734336 - rs2838556 - rs1785437 - rs1618355 - rs1612472 - rs933151 - rs749909 | T-T-C-C-C-C-A T-T-C-C-C-C-A | TRPM2 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.61, X<sup>2</sup>=0.26; Global P-value of 1.5E-17 (1.05E-16 after correcting for multiple testing) More... | Negative | |
| Xu, C., 2006 | rs734336 - rs2838556 - rs1785437 - rs1618355 - rs1612472 - rs933151 - rs749909 | T-T-T-A-T-T-G T-T-T-A-T-T-G | TRPM2 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.206, X<sup>2</sup>=1.6; Global P-value of 1.5E-17 (1.05E-16 after correcting for multiple testing) More... | Negative | |
| Xu, C., 2006 | rs734336 - rs2838556 - rs1785437 - rs1618355 - rs1612472 - rs933151 - rs749909 | T-T-C-C-C-C-G T-T-C-C-C-C-G | TRPM2 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.538, X<sup>2</sup>=0.38; Global P-value of 1.5E-17 (1.05E-16 after correcting for multiple testing) More... | Negative | |
| Xu, C., 2006 | rs734336 - rs2838556 - rs1785437 - rs1618355 - rs1612472 - rs933151 - rs749909 | T-T-T-A-T-T-A T-T-T-A-T-T-A | TRPM2 | COCAPHASE P-value = ...... COCAPHASE P-value = 5.6E-15 , X<sup>2</sup>=61.04; Global P-value of 1.5E-17 (1.05E-16 after correcting for multiple testing) More... | Positive | |
| Roche, S., 2007 | rs734336 - rs2096860 | TRPM2 | TDT P-value = 0.426,...... TDT P-value = 0.426, X<sup>2</sup>=1.706 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| Harvey, M., 2007 | rs7305115 - rs1007023 - rs4290270 | G-T-T G-T-T | TPH2 | cocaphase P-value = ...... cocaphase P-value = 0.125, PHASE P-value = 0.063 in case-control sample; Cocaphase global P-value = 0.018, PHASE global P-value = 0.011 More... | A significantly posi...... A significantly positive result was observed with the haplotype comprising the SNPs rs7305115, rs1007023, and rs4290270 More... | Negative |
| Harvey, M., 2007 | rs7305115 - rs1007023 - rs4290270 | A-G-A A-G-A | TPH2 | cocaphase P-value = ...... cocaphase P-value = 0.243, PHASE P-value = 0.167 in case-control sample; Cocaphase global P-value = 0.018, PHASE global P-value = 0.011 More... | A significantly posi...... A significantly positive result was observed with the haplotype comprising the SNPs rs7305115, rs1007023, and rs4290270 More... | Negative |
| Harvey, M., 2007 | rs7305115 - rs1007023 - rs4290270 | A-T-T A-T-T | TPH2 | cocaphase P-value = ...... cocaphase P-value = 0.043, PHASE P-value = 0.03 in case-control sample; Cocaphase global P-value = 0.018, PHASE global P-value = 0.011 More... | haplotype A-T-T was ...... haplotype A-T-T was over-represented in cases More... | Positive |
| Harvey, M., 2007 | rs7305115 - rs1007023 - rs4290270 | A-T-A A-T-A | TPH2 | cocaphase P-value = ...... cocaphase P-value = 0.16, PHASE P-value = 0.056 in case-control sample; Cocaphase global P-value = 0.018, PHASE global P-value = 0.011 More... | haplotype A-T-A was ...... haplotype A-T-A was over-represented in controls More... | Negative |
| Harvey, M., 2007 | rs7305115 - rs1007023 - rs4290270 | G-T-A G-T-A | TPH2 | cocaphase P-value = ...... cocaphase P-value = 0.222, PHASE P-value = 0.339 in case-control sample; Cocaphase global P-value = 0.018, PHASE global P-value = 0.011 More... | A significantly posi...... A significantly positive result was observed with the haplotype comprising the SNPs rs7305115, rs1007023, and rs4290270 More... | Negative |
| Harvey, M., 2007 | rs7305115 - rs1007023 - rs4290270 | A-G-T A-G-T | TPH2 | cocaphase P-value = ...... cocaphase P-value = 0.241, PHASE P-value = 0.172 in case-control sample; Cocaphase global P-value = 0.018, PHASE global P-value = 0.011 More... | A significantly posi...... A significantly positive result was observed with the haplotype comprising the SNPs rs7305115, rs1007023, and rs4290270 More... | Negative |
| Pickard, B. S.,2009 | rs729217 - rs7141245 | A-T A-T | NPAS3 | Individual P-Value =...... Individual P-Value = 0.0016, OR= 1.3974 (95% CI: 1.1352-1.7202) More... | Significant associat...... Significant association with BPD was found. More... | Positive |
| Palo, O. M.,2010 | rs720974 - rs1414237 | A-G A-G | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=1.746, FBAT P-value = 0.08 More... | No significant asso...... No significant association was found . More... | Negative |
| Kranz, T. M.,2012 | rs7171233 - rs7165988 - rs2172835 | T-C-C T-C-C | C15orf53 | CHI SQUARE = 1.546,P...... CHI SQUARE = 1.546,P-value = 0.2137 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Kranz, T. M.,2012 | rs7171233 - rs7165988 - rs2172835 | A-G-T A-G-T | C15orf53 | CHI SQUARE = 1.164,P...... CHI SQUARE = 1.164,P-value = 0.2806 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Zeng, Z.,2011 | rs716934 - rs9566931 - rs9315897 - rs2122246 | A-A-C-G A-A-C-G | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.227, permutated P-value = 0.904 for BPD; P-value = 0.321, permutated P-value = 0.973 for BPDI More... | No significant asso...... No significant association was found . More... | Negative |
| Zeng, Z.,2011 | rs716934 - rs9566931 - rs9315897 - rs2122246 | A-A-T-G A-A-T-G | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.37, permutated P-value = 0.994 for BPD; P-value = 0.089, permutated P-value = 0.554 for BPDI More... | No significant asso...... No significant association was found . More... | Negative |
| Zeng, Z.,2011 | rs716934 - rs9566931 - rs9315897 - rs2122246 | T-A-T-A T-A-T-A | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.058, permutated P-value = 0.367 for BPD; P-value = 0.005, permutated P-value = 0.036 for BPDI More... | Significant associat...... Significant association was found in BPDI. More... | Positive |
| Zeng, Z.,2011 | rs716934 - rs9566931 - rs9315897 - rs2122246 | T-A-T-G T-A-T-G | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.735, permutated P-value = 1 for BPD; P-value = 0.58, permutated P-value = 1 for BPDI More... | No significant asso...... No significant association was found . More... | Negative |
| Zeng, Z.,2011 | rs716934 - rs9566931 - rs9315897 - rs2122246 | T-G-T-G T-G-T-G | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.989, permutated P-value = 1 for BPD; P-value = 0.392, permutated P-value = 0.992 for BPDI More... | No significant asso...... No significant association was found . More... | Negative |
| Severinsen, J. E., 2006 (b) | rs715519 - rs2272843 - rs3810971 - rs137932 | MAPK8IP2 MOV10L1 | P-value = 0.4475 in ...... P-value = 0.4475 in BD, P-value = 0.4123 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs715519 - rs2272843 - rs3810971 | MAPK8IP2 MOV10L1 | P-value = 0.3063 in ...... P-value = 0.3063 in BD, P-value = 0.4568 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs715519 - rs2272843 | MAPK8IP2 MOV10L1 | P-value = 0.6392 in ...... P-value = 0.6392 in BD, P-value = 0.7516 in BD and SZ More... | Negative | ||
| Wen, Z., 2016 | rs7113041–rs12278912 | G-A G-A | NRGN | P(unadj)-value=0.000...... P(unadj)-value=0.000405, Corrected P-value=0.000540, OR=0.758, 95%CI=0.650-0.884 More... | It is particularly n...... It is particularly noticeable that one haplotype, GA, was significantly associated with schizophrenia, major depressive disorder, and bipolar disorder. The global P values for them were 0.004, 0.014, and 0.001 respectively, implicating a common risk region in NRGN for major psychiatric disorders. More... | Positive |
| Pickard, B. S., 2006 | rs7111184 - rs2156635 - rs949056 - rs949054 | GRIK4 | P-value = 0.489 betw...... P-value = 0.489 between SCZ cases and controls; P-value = 0.271 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs7111184 - rs2156635 - rs949056 | GRIK4 | P-value = 0.486 betw...... P-value = 0.486 between BPD cases and controls; P-value = 0.173 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs7111184 - rs2156635 | GRIK4 | P-value = 0.351 betw...... P-value = 0.351 between BPD cases and controls; P-value = 0.277 between all cases and controls More... | Negative | ||
| Severinsen, J. E., 2006 (a) | rs710193 - rs133073 - rs133070 - rs133069 - rs133068 | ST13 MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.1722, CLUMP T4 P-value = 0.239 in BPD and SZ, CLUMP T1 P-value = 0.1745, CLUMP T4 P-value = 0.2831 in BPD; Empirical overall P-value = 0.1895 in BPD and SZ, Empirical overall P-value = 0.0018 in BPD More... | Positive | ||
| Severinsen, J. E., 2006 (a) | rs710193 - rs133073 - rs133070 - rs133069 | ST13 MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.1755, CLUMP T4 P-value = 0.2417 in BPD and SZ, CLUMP T1 P-value = 0.1753, CLUMP T4 P-value = 0.2821 in BPD; Empirical overall P-value = 0.079 in BPD and SZ, Empirical overall P-value = 0.0252 in BPD More... | Positive | ||
| Severinsen, J. E., 2006 (a) | rs710193 - rs133073 - rs133070 | ST13 MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.1158, CLUMP T4 P-value = 0.1697 in BPD and SZ, CLUMP T1 P-value = 0.085, CLUMP T4 P-value = 0.194 in BPD; Empirical overall P-value = 0.0715 in BPD and SZ, Empirical overall P-value = 0.2251 in BPD More... | Negative | ||
| Severinsen, J. E., 2006 (a) | rs710193 - rs133073 | ST13 MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.4522, CLUMP T4 P-value = 0.4361 in BPD and SZ, CLUMP T1 P-value = 0.8264, CLUMP T4 P-value = 0.86 in BPD; Empirical overall P-value = 0.1247 in BPD and SZ, Empirical overall P-value = 0.1197 in BPD More... | Negative | ||
| Wang, T.,2012 | rs7090018 - rs11199993 | T-G T-G | FGFR2 | P-value = 0.125, Per...... P-value = 0.125, Permutated P-value = 0.739 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Wang, T.,2012 | rs7090018 - rs11199993 | T-C T-C | FGFR2 | OR=1.298, 95% CI=1.1...... OR=1.298, 95% CI=1.120-1.504; P-value = 0.0005, P-value = 0.006 after permutation More... | T-C(rs7090018 and rs...... T-C(rs7090018 and rs11199993), was found to be a risk haplotype More... | Positive |
| Wang, T.,2012 | rs7090018 - rs11199993 | G-G G-G | FGFR2 | P-value = 0.058, Per...... P-value = 0.058, Permutated P-value = 0.455 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Wang, T.,2012 | rs7090018 - rs11199993 | T-G T-G | FGFR2 | P-value=0.125, Permu...... P-value=0.125, Permutated P-value=0.739 More... | The haplotype block ...... The haplotype block was also found to be associated with BPD, after permutation. T-G is not the risk haplotype. More... | Negative |
| Wang, T.,2012 | rs7090018 - rs11199993 | T-C T-C | FGFR2 | P-value=0.0005, Perm...... P-value=0.0005, Permutated P-value=0.006, OR (95% CI)=1.298 (1.120-1.504) More... | The haplotype block ...... The haplotype block was also found to be associated with BPD, after permutation. T-C was found to be a risk haplotype. More... | Positive |
| Wang, T.,2012 | rs7090018 - rs11199993 | G-G G-G | FGFR2 | P-value=0.058, Permu...... P-value=0.058, Permutated P-value=0.455 More... | The haplotype block ...... The haplotype block was also found to be associated with BPD, after permutation. G-G is not the risk haplotype. More... | Negative |
| McGrath, C. L.,2009 | rs7022435 - rs17691614 - rs7032677 | RORB | haplotype(A-A-A):P-v...... haplotype(A-A-A):P-value = 8.17E-07, Permuted P-value < 0.001 More... | Association was obse...... Association was observed only in the case-control sample. More... | Positive | |
| Gutierrez-Fernandez, A., 2014 | rs7005606 - rs6468119 - rs3802158 - rs7834206 | T-T-C-C T-T-C-C | NRG1 | All patients: X...... All patients: X2=5.017, P-value=0.1408, P-value(uncorrected)=0.0251; Bipolar disorder patients: X2=11.608, P-value=0.0037, P-value(uncorrected)=0.0007. More... | The strongest associ...... The strongest association observed in this study between NRG1 SNPs and BD involved a novel haplotype combination of markers rs7005606, rs6468119, rs3802158, and rs7834206 TTCC (P=0.0037). More... | Positive |
| Gutierrez-Fernandez, A., 2014 | rs7005606 - rs6468119 - rs3802158 - rs7834206 | G-C-T-A G-C-T-A | NRG1 | All patients: X...... All patients: X2=5.141, P-value=0.1362, P-value(uncorrected)=0.0234; Bipolar disorder patients: X2=8.25, P-value=0.0245, P-value(uncorrected)=0.0041. More... | Significant associat...... Significant association between this block and BD was observed. More... | Positive |
| Gutierrez-Fernandez, A., 2014 | rs7005606 - rs6468119 - rs3802158 - rs7834206 | T-C-C-C T-C-C-C | NRG1 | All patients: X...... All patients: X2=0.422, P-value=0.9813, P-value(uncorrected)=0.5157; Bipolar disorder patients: X2=2.402, P-value=0.4611, P-value(uncorrected)=0.1212. More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Thomson, P. A., 2007 | rs6988339 - rs3757930 - rs10103750 - rs10503932 | NRG1 | P-value = 0.0117 for...... P-value = 0.0117 for BP, P-value = 0.002 for SCZ and BP More... | Positive | ||
| Thomson, P. A., 2007 | rs6988339 - rs3757930 - rs10103750 | NRG1 | P-value = 0.0044 for...... P-value = 0.0044 for BP, P-value = 0.0005 for SCZ and BP More... | Positive | ||
| Thomson, P. A., 2007 | rs6988339 - rs3757930 | NRG1 | P-value = 0.0045 for...... P-value = 0.0045 for BP, P-value = 0.0004 for SCZ and BP More... | Positive | ||
| Walker, R. M.,2010 | rs6988339 - rs3757930 | NRG1 | Haplotypic associati...... Haplotypic association:P-value = 0.0045 for Scottish 1, P-value = 0.45 for Scottish 2, P-value = 0.34 for German, P-value = 0.072 for merged Scottish, P-value = 0.072 for merged all More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Szczepankiewicz, A.,2009(a) | rs6916861 - rs3730353 | G-C G-C | FYN | Haplotypic associati...... Haplotypic association:P-value = 0.042, X<sup>2</sup>=4.127 More... | Significant associat...... Significant association was found. More... | Positive |
| Szczepankiewicz, A.,2009(a) | rs6916861 - rs3730353 | T-T T-T | FYN | Haplotypic associati...... Haplotypic association:P-value = 0.324, X<sup>2</sup>=0.97 More... | No significant asso...... No significant association was found . More... | Negative |
| Iwayama, Y., 2010 | rs6899351 - rs6919681 - rs6904500 | TAT TAT | FABP7 | P-value = 0.219, glo...... P-value = 0.219, global P-value = 0.5686 More... | Negative | |
| Iwayama, Y., 2010 | rs6899351 - rs6919681 - rs6904500 | TAC TAC | FABP7 | P-value = 0.577, glo...... P-value = 0.577, global P-value = 0.5686 More... | Negative | |
| Iwayama, Y., 2010 | rs6899351 - rs6919681 - rs6904500 | TGC TGC | FABP7 | P-value = 0.334, glo...... P-value = 0.334, global P-value = 0.5686 More... | Negative | |
| Iwayama, Y., 2010 | rs6899351 - rs6919681 - rs6904500 | CGC CGC | FABP7 | P-value = 0.741, glo...... P-value = 0.741, global P-value = 0.5686 More... | Negative | |
| Schosser, A.,2011 | rs6788448 - rs281817 | ATP13A4 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.261, global P-value = 0.118 More... | No significant asso...... No significant association was found . More... | Negative | |
| Schosser, A.,2011 | rs6785339 - rs4459932 | TM4SF19 UBXN7 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.342, global P-value = 0.107 More... | No significant asso...... No significant association was found . More... | Negative | |
| Schosser, A.,2011 | rs6778889 - rs9311 | SMCO1 WDR53 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.546, global P-value = 0.184 More... | No significant asso...... No significant association was found . More... | Negative | |
| Schosser, A.,2011 | rs6778889 - rs2341399 | SMCO1 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.413, global P-value = 0.157 More... | No significant asso...... No significant association was found . More... | Negative | |
| Schosser, A.,2011 | rs6778879 - rs6785339 | G-T G-T | TCTEX1D2 TM4SF19 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.012, global P-value = 0.011 More... | Significant associat...... Significant association was found in both individual P-value and global P-value. More... | Positive |
| Fukuo, Y.,2010 | rs6693503 - rs1805054 - rs4912138 - rs3790757 - rs9659997 | HTR6 | Haplotype-wise analy...... Haplotype-wise analysis:global P-value = 0.515 More... | No significant asso...... No significant association was found . More... | Negative | |
| Fukuo, Y.,2010 | rs6693503 - rs1805054 - rs4912138 - rs3790757 | HTR6 | Haplotype-wise analy...... Haplotype-wise analysis:global P-value = 0.318 More... | No significant asso...... No significant association was found . More... | Negative | |
| Fukuo, Y.,2010 | rs6693503 - rs1805054 - rs4912138 | HTR6 | Haplotype-wise analy...... Haplotype-wise analysis:global P-value = 0.297 More... | No significant asso...... No significant association was found . More... | Negative | |
| Fukuo, Y.,2010 | rs6693503 - rs1805054 | HTR6 | Haplotype-wise analy...... Haplotype-wise analysis:global P-value = 0.426 More... | No significant asso...... No significant association was found . More... | Negative | |
| Schosser, A., 2010 | rs6675281 - rs12133766 - rs1000731 | CGA CGA | DISC1 | Individual P-value =...... Individual P-value = 0.09, global P-value = 0.39 More... | Negative | |
| Palo, O. M., 2007 | rs6675281 - rs1000731 - rs821616 | T-C-T T-C-T | DISC1 | Individual P-value =...... Individual P-value = 0.022 in all, P-value = 0.105 in males, P-value = 0.59 in females; global P-value = 0.033 in all, P-value = 0.201 in males, P-value = 0.486 in females, with bipolar spectrum disorder More... | Positive | |
| Palo, O. M., 2007 | rs6675281 - rs1000731 | T-C T-C | DISC1 | Individual P-value =...... Individual P-value = 0.417 in all, P-value = 0.569 in males, P-value = 0.662 in females; global P-value = 0.274 in all, P-value = 0.727 in males, P-value = 0.321 in females, with bipolar spectrum disorder More... | Negative | |
| Pickard, B. S., 2006 | rs6589846 - rs4430518 - rs433110 - rs7111184 | GRIK4 | P-value = 0.578 betw...... P-value = 0.578 between SCZ cases and controls; P-value = 0.335 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs6589846 - rs4430518 - rs433110 | GRIK4 | P-value = 0.506 betw...... P-value = 0.506 between BPD cases and controls; P-value = 0.34 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs6589846 - rs4430518 | GRIK4 | P-value = 0.349 betw...... P-value = 0.349 between BPD cases and controls; P-value = 0.115 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs6589832 - rs7925270 - rs3133855 - rs3133226 | GRIK4 | P-value = 0.125 betw...... P-value = 0.125 between SCZ cases and controls; P-value = 0.831 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs6589832 - rs7925270 - rs3133855 - rs3133226 | G-C-T-C G-C-T-C | GRIK4 | P-value = 0.0018, Co...... P-value = 0.0018, Correction P-value = 0.3187 More... | Positive | |
| Pickard, B. S., 2006 | rs6589832 - rs7925270 - rs3133855 | GRIK4 | P-value = 0.038 betw...... P-value = 0.038 between BPD cases and controls; P-value = 0.8 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs6589832 - rs7925270 - rs3133855 | G-C-T G-C-T | GRIK4 | P-value = 0.0018, Co...... P-value = 0.0018, Correction P-value = 0.2258 More... | Positive | |
| Pickard, B. S., 2006 | rs6589832 - rs7925270 | GRIK4 | P-value = 0.48 betwe...... P-value = 0.48 between BPD cases and controls; P-value = 0.913 between all cases and controls More... | Negative | ||
| Schosser, A.,2011 | rs6583248 - rs2885470 | KIAA0226 FYTTD1 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.348, global P-value = 0.193 More... | No significant asso...... No significant association was found . More... | Negative | |
| Kakiuchi, C., 2007 (b) | rs6519194 - rs882565 - rs4821907 - rs1028321 | G-C-C-G G-C-C-G | ATF4 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.4931 in Japanese samples; TDT P-value = 0.5813 in NIMH samples; global P-value = 0.0156 in BPII patients, P-value = 0.00143 for G-C-C-G haplotype More... | Haplotype analysis o...... Haplotype analysis of ATF4 in BPII patients and controls of Japanese samples showed the significant association. rs6519194(G)-rs882565(C)-rs4821907(C)-rs1028321(G) haplotype was significantly less in cases. More... | Positive |
| Kakiuchi, C., 2007 (b) | rs6519194 - rs882565 - rs4821907 | ATF4 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.8182 in Japanese samples; TDT P-value = 0.5464 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Kakiuchi, C., 2007 (b) | rs6519194 - rs882565 | ATF4 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.9401 in Japanese samples; TDT P-value = 0.5841 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Roche, S., 2007 | rs6518189 - rs4818922 | TRPM2 | TDT P-value = 0.609,...... TDT P-value = 0.609, X<sup>2</sup>=0.992 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| Bloch, P. J., 2010 | rs650727 - rs589247 - rs669838 - rs636173 | CGGG CGGG | IMPA2 | Chi square=2.783, P-...... Chi square=2.783, P-value = 0.0953, permutation P-value = 0.6677 More... | Haplotype analysis d...... Haplotype analysis did not show any statistically significant associations. More... | Negative |
| Bloch, P. J., 2010 | rs650727 - rs589247 - rs669838 - rs636173 | TATA TATA | IMPA2 | Chi square=2.071, P-...... Chi square=2.071, P-value = 0.1501, permutation P-value = 0.8476 More... | Haplotype analysis d...... Haplotype analysis did not show any statistically significant associations. More... | Negative |
| Bloch, P. J., 2010 | rs650727 - rs589247 - rs669838 - rs636173 | CGTA CGTA | IMPA2 | Chi square=1.627, P-...... Chi square=1.627, P-value = 0.2021, permutation P-value = 0.9014 More... | Haplotype analysis d...... Haplotype analysis did not show any statistically significant associations. More... | Negative |
| Zhang, J.,2009 | rs6506640 - rs906807 | A-C A-C | NDUFV2 | Haplotypic associati...... Haplotypic association:Global P-value = 0.012, Global P-value(permutation)=0.03, Individual P-value = 0.625 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Zhang, J.,2009 | rs6506640 - rs906807 | A-T A-T | NDUFV2 | Haplotypic associati...... Haplotypic association:Global P-value = 0.012, Global P-value(permutation)=0.03, Individual P-value = 0.0065, Individual P-value(permutation)=0.014 More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhang, J.,2009 | rs6506640 - rs906807 | G-T G-T | NDUFV2 | Haplotypic associati...... Haplotypic association:Global P-value = 0.012, Global P-value(permutation)=0.03, Individual P-value = 1.000 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Palo, O. M.,2010 | rs648619 - rs1833083 | G-G G-G | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=-1.008, FBAT P-value = 0.313 More... | No significant asso...... No significant association was found . More... | Negative |
| Cao L., 2014 | rs6468121 - rs2466044 | A-A A-A | NRG1 | Globe: X<sup>2...... Globe: X<sup>2</sup>=16.69, Bonf P-value=0.032; A-A: X<sup>2</sup>=16.65, Bonf P-value=0.006 More... | All of these haploty...... All of these haplotypes were more common in controls than in BPI patients, suggesting that its presence might indicate a decreased risk of BPI. More... | Positive |
| Atz, M. E., 2007 | rs646558 - rs2303377 | C-T, C-(T/C), (C/A)-...... C-T, C-(T/C), (C/A)-(T/C) More... | NCAM1 | Chi-square P-value =...... Chi-square P-value = <0.0001, X<sup>2</sup>=21.99, d.f.=2 for BD; chi-square P-value = <0.0001, X<sup>2</sup>=27.90, d.f.=2 for BD and SZ More... | Three of the two mar...... Three of the two marker haplotypes for rs646558 and rs2303377 showed varying frequencies between bipolar and controls. More... | Positive |
| Fatjo-Vilas, M., 2016 | rs645649 - rs582262 | C-C C-C | NRN1 | P(unadj)-value=0.004...... P(unadj)-value=0.0043 More... | The result in Block ...... The result in Block 2 remained significant after permutation procedure; then, this haplotype was considered a risk haplotype for SSD and BPD. More... | Positive |
| Kishi, T.,2009(b) | rs6313 - rs2070040 - rs1928040 - rs7997012 | HTR2A | likelihood ratio tes...... likelihood ratio test:Global P-value = 0.344 in BP More... | No significant asso...... No significant association was found with BP. More... | Negative | |
| Kishi, T.,2011(b) | rs6295 - rs878567 | C-C C-C | HTR1A | Haplotype analysis:l...... Haplotype analysis:likelihood ratio test:OR=1.38, 95%CI=1.19-1.59, individual P-value = 1.76E-05; global P-value = 2.03E-05, corrected global P-value = 2.44E-05 for BD More... | Significant associat...... Significant association was found in both individual P-value and global P-value in BD. More... | Positive |
| Kishi, T.,2011(b) | rs6295 - rs878567 | G-C G-C | HTR1A | Haplotype analysis:l...... Haplotype analysis:likelihood ratio test:OR=1.38, 95%CI=1.19-1.59, individual P-value = 1.76E-05; global P-value = 2.03E-05, corrected global P-value = 2.44E-05 for BD More... | Significant associat...... Significant association was found in both individual P-value and global P-value in BD. More... | Positive |
| Neves-Pereira, M.,2005 | rs6265 - microsatellite (GT)n | A-(GT1) A-(GT1) | BDNF | For BPAD, P-value &g...... For BPAD, P-value > 0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Neves-Pereira, M.,2005 | rs6265 - microsatellite (GT)n | G-(GT1) G-(GT1) | BDNF | For BPAD, P-value &g...... For BPAD, P-value > 0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Met-221 Met-221 | BDNF | P-value = 0.811, X&l...... P-value = 0.811, X<sup>2</sup>=0.06, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Met-223 Met-223 | BDNF | P-value = 0.236, X&l...... P-value = 0.236, X<sup>2</sup>=1.41, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Met-225 Met-225 | BDNF | P-value = 0.844, X&l...... P-value = 0.844, X<sup>2</sup>=0.04, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Met-227 Met-227 | BDNF | P-value = 0.018, X&l...... P-value = 0.018, X<sup>2</sup>=5.59, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The two-locus haplot...... The two-locus haplotype analyses indicate non-significant under-transmission of the two haplotypes carrying the Met allele (Met-227 and Met-231). The global two locus test indicates significant transmission distortion. More... | Positive |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Met-229 Met-229 | BDNF | P-value = 0.68, X<...... P-value = 0.68, X<sup>2</sup>=0.17, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Met-231 Met-231 | BDNF | P-value = 0.02, X<...... P-value = 0.02, X<sup>2</sup>=5.4, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The two-locus haplot...... The two-locus haplotype analyses indicate non-significant under-transmission of the two haplotypes carrying the Met allele (Met-227 and Met-231). The global two locus test indicates significant transmission distortion. More... | Positive |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Met-233 Met-233 | BDNF | P-value = 0.699, X&l...... P-value = 0.699, X<sup>2</sup>=0.15, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Val-219 Val-219 | BDNF | P-value = 0.764, X&l...... P-value = 0.764, X<sup>2</sup>=0.09, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Val-221 Val-221 | BDNF | P-value = 0.327, X&l...... P-value = 0.327, X<sup>2</sup>=0.96, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Val-223 Val-223 | BDNF | P-value = 0.207, X&l...... P-value = 0.207, X<sup>2</sup>=1.59, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Val-225 Val-225 | BDNF | P-value = 0.953, X&l...... P-value = 0.953, X<sup>2</sup>=0, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Val-227 Val-227 | BDNF | P-value = 0.006, X&l...... P-value = 0.006, X<sup>2</sup>=7.67, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The two-locus haplot...... The two-locus haplotype analyses indicate nominally significant over-transmission of the Val-227 haplotype. The global two locus test indicates significant transmission distortion. More... | Positive |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Val-229 Val-229 | BDNF | P-value = 0.748, X&l...... P-value = 0.748, X<sup>2</sup>=0.1, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Val-231 Val-231 | BDNF | P-value = 0.533, X&l...... P-value = 0.533, X<sup>2</sup>=0.39, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Kremeyer, B., 2006 | rs6265 - BDNF_(CA) | Val-233 Val-233 | BDNF | P-value = 0.274, X&l...... P-value = 0.274, X<sup>2</sup>=1.2, df=1; global P-value = 0.025, X<sup>2</sup>=16.059, df=7 More... | The global two locus...... The global two locus test indicates significant transmission distortion. More... | Negative |
| Ivanova, M. A.,2012 | rs6265 - rs16917237 - rs12273363 | C-G-T C-G-T | BDNF | Association results:...... Association results:genotype frequency,0.68%/0.58%(case/control); P=0.002,narrow; 0.66%/0.59%(case/control); P=0.025, broad More... | The haplotype was mo...... The haplotype was more frequently found in the group of patients compared with controls. More... | Positive |
| Ivanova, M. A.,2012 | rs6265 - rs16917237 | C-G C-G | BDNF | Association results:...... Association results:genotype frequency,0.78%/0.71%(case/control); P=0.0185, narrow More... | The haplotype was mo...... The haplotype was more frequently found in the group of patients compared with controls. More... | Positive |
| Etain, B., 2010 | rs6039769 - rs2076239 - rs362987 - rs363006 | AAAG AAAG | SNAP25 | P-value = 0.004 for ...... P-value = 0.004 for 'AAAG' haplotype More... | have significant P-v...... have significant P-values in early onset subgroup More... | Positive |
| Pickard, B. S., 2006 | rs602104 - rs2276319 - rs513548 - rs2282586 | GRIK4 | P-value = 0.136 betw...... P-value = 0.136 between SCZ cases and controls; P-value = 0.34 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs602104 - rs2276319 - rs513548 - rs2282586 | C-A-T-G C-A-T-G | GRIK4 | P-value = 0.008 P-value = 0.008 | Positive | |
| Pickard, B. S., 2006 | rs602104 - rs2276319 - rs513548 | GRIK4 | P-value = 0.137 betw...... P-value = 0.137 between BPD cases and controls; P-value = 0.314 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs602104 - rs2276319 | GRIK4 | P-value = 0.056 betw...... P-value = 0.056 between BPD cases and controls; P-value = 0.274 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs602104 - rs2276319 | C-A C-A | GRIK4 | P-value = 0.0064 P-value = 0.0064 | Positive | |
| Severinsen, J. E., 2006 (b) | rs6010260 - rs138881 - rs138880 - rs2239848 | MLC1 BRD1 | P-value = 0.5603 in ...... P-value = 0.5603 in BD, P-value = 0.3086 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs6010260 - rs138881 - rs138880 | MLC1 BRD1 | P-value = 0.6108 in ...... P-value = 0.6108 in BD, P-value = 0.2102 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs6010260 - rs138881 | MLC1 BRD1 | P-value = 0.6883 in ...... P-value = 0.6883 in BD, P-value = 0.4043 in BD and SZ More... | Negative | ||
| Fullerton, J. M.,2010 | rs5746136 - rs4880 | T-G T-G | SOD2 | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>= 8.94, global P-value = 0.03 ; X<sup>2</sup>= 9.91, individual P-value = 0.002, OR = 3.257 for broad model More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Thomson, P. A., 2007 | rs553950 - rs327329 - rs7007662 - rs1481762 | NRG1 | P-value = 0.0064 for...... P-value = 0.0064 for BP, P-value = 0.0146 for SZ and BP combined More... | Positive | ||
| Thomson, P. A., 2007 | rs553950 - rs327329 - rs7007662 | NRG1 | P-value = 0.0011 for...... P-value = 0.0011 for BP, P-value = 0.0034 for SZ and BP combined More... | the haplotype is nom...... the haplotype is nominally associated with BP alone and spans LD blocks 3 and 4 More... | Positive | |
| Walker, R. M.,2010 | rs553950 - rs327329 | NRG1 | Haplotypic associati...... Haplotypic association:P-value = 0.044 for Scottish 1, P-value = 0.3 for Scottish 2, P-value = 0.058 for merged Scottish More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Shi, J., 2008 (d) | rs534654 - rs2412648 - rs4340844 - rs11735267 - rs6850524 - rs7660668 | GAAACG GAAACG | CLOCK | P-value = 0.025 P-value = 0.025 | Several haplotypes c...... Several haplotypes consisting of six SNPs at the CLOCK gene region also showed nominal association with disease. However, none of these associations reached gene-wide or experiment-wide significance after correction for multiple-testing. More... | Positive |
| Shi, J., 2008 (d) | rs534654 - rs2412648 - rs4340844 - rs11735267 - rs6850524 - rs7660668 | GACAGC GACAGC | CLOCK | P-value = 0.028 P-value = 0.028 | Several haplotypes c...... Several haplotypes consisting of six SNPs at the CLOCK gene region also showed nominal association with disease. However, none of these associations reached gene-wide or experiment-wide significance after correction for multiple-testing. More... | Positive |
| Shi, J., 2008 (d) | rs534654 - rs2412648 - rs4340844 - rs11735267 - rs6850524 - rs7660668 | AAAGCC AAAGCC | CLOCK | P-value = 0.034 P-value = 0.034 | Several haplotypes c...... Several haplotypes consisting of six SNPs at the CLOCK gene region also showed nominal association with disease. However, none of these associations reached gene-wide or experiment-wide significance after correction for multiple-testing. More... | Positive |
| Pickard, B. S., 2006 | rs513548 - rs2282586 - rs1944522 | GRIK4 | P-value = 0.01 betwe...... P-value = 0.01 between BPD cases and controls; P-value = 0.054 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs513548 - rs2282586 - rs1944522 | T-G-C T-G-C | GRIK4 | P-value = 0.0021 P-value = 0.0021 | Positive | |
| Pickard, B. S., 2006 | rs513548 - rs2282586 | GRIK4 | P-value = 0.03 betwe...... P-value = 0.03 between BPD cases and controls; P-value = 0.093 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs513548 - rs2282586 | T-G T-G | GRIK4 | P-value = 0.0037 P-value = 0.0037 | Positive | |
| Barden, N., 2006 | rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 - rs3751144 - rs3751143 - rs1653625 | C-A-G-C-A-C-A-C C-A-G-C-A-C-A-C | P2RX7 | chi-square P-value =...... chi-square P-value = 0.159, LRS (global P-value)=0.041 More... | We identified global...... We identified global significant P-values for blocks 2 with P-value = 0.0410. The haplotype block 2 defines the last six exons of the P2RX7 gene, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 - rs3751144 - rs3751143 - rs1653625 | C-G-G-C-A-C-C-C C-G-G-C-A-C-C-C | P2RX7 | chi-square P-value =...... chi-square P-value = 0.979, LRS (global P-value)=0.041 More... | We identified global...... We identified global significant P-values for blocks 2 with P-value = 0.0410. The haplotype block 2 defines the last six exons of the P2RX7 gene, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 - rs3751144 - rs3751143 - rs1653625 | T-G-A-C-G-C-A-A T-G-A-C-G-C-A-A | P2RX7 | chi-square P-value =...... chi-square P-value = 0.551, LRS (global P-value)=0.041 More... | We identified global...... We identified global significant P-values for blocks 2 with P-value = 0.0410. The haplotype block 2 defines the last six exons of the P2RX7 gene, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 - rs3751144 - rs3751143 - rs1653625 | T-G-A-C-A-C-A-A T-G-A-C-A-C-A-A | P2RX7 | chi-square P-value =...... chi-square P-value = 0.095, LRS (global P-value)=0.041 More... | We identified global...... We identified global significant P-values for blocks 2 with P-value = 0.0410. The haplotype block 2 defines the last six exons of the P2RX7 gene, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 - rs3751144 - rs3751143 - rs1653625 | C-G-G-G-A-T-A-A C-G-G-G-A-T-A-A | P2RX7 | chi-square P-value =...... chi-square P-value = 0.346, LRS (global P-value)=0.041 More... | We identified global...... We identified global significant P-values for blocks 2 with P-value = 0.0410. The haplotype block 2 defines the last six exons of the P2RX7 gene, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 - rs3751144 - rs3751143 - rs1653625 | C-G-G-C-A-C-A-C C-G-G-C-A-C-A-C | P2RX7 | chi-square P-value =...... chi-square P-value = 0.249, LRS (global P-value)=0.041 More... | We identified global...... We identified global significant P-values for blocks 2 with P-value = 0.0410. The haplotype block 2 defines the last six exons of the P2RX7 gene, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 - rs3751144 - rs3751143 - rs1653625 | C-G-A-C-A-C-A-A C-G-A-C-A-C-A-A | P2RX7 | chi-square P-value =...... chi-square P-value = 0.101, LRS (global P-value)=0.041 More... | We identified global...... We identified global significant P-values for blocks 2 with P-value = 0.0410. The haplotype block 2 defines the last six exons of the P2RX7 gene, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 - rs3751144 - rs3751143 - rs1653625 | C-A-G-C-G-C-A-C C-A-G-C-G-C-A-C | P2RX7 | chi-square P-value =...... chi-square P-value = 0.012, LRS (global P-value)=0.041 More... | We identified global...... We identified global significant P-values for blocks 2 with P-value = 0.0410. The haplotype block 2 defines the last six exons of the P2RX7 gene, hence supporting the prior single marker analysis. More... | Positive |
| Barden, N., 2006 | rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 - rs3751144 - rs3751143 - rs1653625 | T-G-G-C-A-C-A-C T-G-G-C-A-C-A-C | P2RX7 | chi-square P-value =...... chi-square P-value = 0.133, LRS (global P-value)=0.041 More... | We identified global...... We identified global significant P-values for blocks 2 with P-value = 0.0410. The haplotype block 2 defines the last six exons of the P2RX7 gene, hence supporting the prior single marker analysis. More... | Negative |
| McQuillin, A.,2009 | rs504677 - rs2230912 | P2RX7 | Haplotypic associati...... Haplotypic association:Global LRT=11.88, df=3, Global empirical P-value = 0.0079 More... | Significant associat...... Significant association with BPD was found. More... | Positive | |
| Schosser, A.,2011 | rs4974539 - rs13070515 | CPN2 LRRC15 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.782, global P-value = 0.356 More... | No significant asso...... No significant association was found . More... | Negative | |
| Pickard, B. S., 2006 | rs4935752 - rs6589846 - rs4430518 - rs433110 | GRIK4 | P-value = 0.434 betw...... P-value = 0.434 between SCZ cases and controls; P-value = 0.128 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs4935752 - rs6589846 - rs4430518 | GRIK4 | P-value = 0.354 betw...... P-value = 0.354 between BPD cases and controls; P-value = 0.16 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs4935752 - rs6589846 | GRIK4 | P-value = 0.706 betw...... P-value = 0.706 between BPD cases and controls; P-value = 0.103 between all cases and controls More... | Negative | ||
| Fukuo, Y.,2010 | rs4912138 - rs3790757 - rs9659997 | HTR6 | Haplotype-wise analy...... Haplotype-wise analysis:global P-value = 0.252 More... | No significant asso...... No significant association was found . More... | Negative | |
| Fukuo, Y.,2010 | rs4912138 - rs3790757 | HTR6 | Haplotype-wise analy...... Haplotype-wise analysis:global P-value = 0.13 More... | No significant asso...... No significant association was found . More... | Negative | |
| Ross, K. A.,2011 | rs4850057 - rs9551988 | PSPC1 | SNP interactions:P-v...... SNP interactions:P-value = 0.62 More... | No significant asso...... No significant association was found . More... | Negative | |
| Ross, K. A.,2011 | rs4850057 - (SNP A-1797773) | SNP interactions:P-v...... SNP interactions:P-value = 0.38 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Kakiuchi, C., 2007 (b) | rs4821907 - rs1028321 | ATF4 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.1748 in Japanese samples; TDT P-value = 0.5742 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Roche, S., 2007 | rs4818917 - rs1556314 | TRPM2 | TDT P-value = 0.117,...... TDT P-value = 0.117, X<sup>2</sup>=4.296 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| Szczepankiewicz, A., 2013 | rs4792887 - rs110402 | C-A C-A | CRHR1 | P-value=0.071, X<...... P-value=0.071, X<sup>2</sup>=3.251 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz, A., 2013 | rs4792887 - rs110402 | C-G C-G | CRHR1 | P-value=0.288, X<...... P-value=0.288, X<sup>2</sup>=1.129 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz, A., 2013 | rs4792887 - rs110402 | T-G T-G | CRHR1 | P-value=0.211, X<...... P-value=0.211, X<sup>2</sup>=1.559 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Li, X.,2009 | rs473938 - rs510110 | NAPG | haplotype frequencie...... haplotype frequencies in bipolar patients and controls:Global P-value = 0.004815, Most associated individual haplotype:T-A, Individual P-value = 0.00103 More... | We detected signific...... We detected significant associations in BP group. More... | Positive | |
| Li, X.,2009 | rs473938 - rs495484 - rs510110 | NAPG | haplotype frequencie...... haplotype frequencies in bipolar patients and controls:Global P-value = 0.007463, Most associated individual haplotype:T-T-A, Individual P-value = 0.001339 More... | We detected signific...... We detected significant associations in BP group. More... | Positive | |
| Li, X.,2009 | rs473938 - rs495484 | NAPG | haplotype frequencie...... haplotype frequencies in bipolar patients and controls:Global P-value = 0.006632, Most associated individual haplotype:T-T, Individual P-value = 0.001235 More... | We detected signific...... We detected significant associations in BP group. More... | Positive | |
| Li, X.,2009 | rs473938 - rs2290279 - rs510110 | NAPG | haplotype frequencie...... haplotype frequencies in bipolar patients and controls:Global P-value = 0.00164, Most associated individual haplotype:T-A-A, Individual P-value = 0.0002869 More... | We detected signific...... We detected significant associations in BP group. More... | Positive | |
| Li, X.,2009 | rs473938 - rs2290279 - rs495484 - rs510110 | NAPG | haplotype frequencie...... haplotype frequencies in bipolar patients and controls:Global P-value = 0.002355, Most associated individual haplotype:T-A-T-A, Individual P-value = 0.0003893 More... | We detected signific...... We detected significant associations in BP group. More... | Positive | |
| Li, X.,2009 | rs473938 - rs2290279 - rs495484 | NAPG | haplotype frequencie...... haplotype frequencies in bipolar patients and controls:Global P-value = 0.001455, Most associated individual haplotype:T-A-T, Individual P-value = 0.0004148 More... | We detected signific...... We detected significant associations in BP group. More... | Positive | |
| Li, X.,2009 | rs473938 - rs2290279 | NAPG | haplotype frequencie...... haplotype frequencies in bipolar patients and controls:Global P-value = 0.0004076, Most associated individual haplotype:T-A, Individual P-value = 0.0001676 More... | We detected signific...... We detected significant associations in BP group. More... | Positive | |
| Gawlik, M., 2006 | rs4713916 - rs1360780 - rs3800373 | G-C-T G-C-T | FKBP5 | OR=0.86 OR=0.86 | In the studied popul...... In the studied population we found two haplotypes, G-C-T and A-T-G, with a cumulated frequency of 86.2% in controls. More... | Negative |
| Gawlik, M., 2006 | rs4713916 - rs1360780 - rs3800373 | A-T-G A-T-G | FKBP5 | OR=1.18 OR=1.18 | In the studied popul...... In the studied population we found two haplotypes, G-C-T and A-T-G, with a cumulated frequency of 86.2% in controls. More... | Negative |
| Gawlik, M., 2006 | rs4713916 - rs1360780 - rs3800373 | A-C-T A-C-T | FKBP5 | OR=1.1 OR=1.1 | Negative | |
| Gawlik, M., 2006 | rs4713916 - rs1360780 - rs3800373 | G-T-G G-T-G | FKBP5 | OR=0.8 OR=0.8 | Negative | |
| Gawlik, M., 2006 | rs4713916 - rs1360780 - rs3800373 | A-T-T A-T-T | FKBP5 | OR=0.88 OR=0.88 | Negative | |
| Gawlik, M., 2006 | rs4713916 - rs1360780 - rs3800373 | G-T-T G-T-T | FKBP5 | OR=0.82 OR=0.82 | Negative | |
| Gawlik, M., 2006 | rs4713916 - rs1360780 - rs3800373 | G-C-G G-C-G | FKBP5 | OR=6.81 OR=6.81 | Odds ratios were not...... Odds ratios were not increased between cases and controls, except the rare haplotype G-C-G (OR 6.81) representing 2.1% of cases, and 0.3% of controls. More... | Negative |
| Gawlik, M., 2006 | rs4713916 - rs1360780 - rs3800373 | A-C-G A-C-G | FKBP5 | OR=0.51 OR=0.51 | Negative | |
| Schosser, A.,2011 | rs4677666 - rs2050806 | ACAP2 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.842, global P-value = 0.419 More... | No significant asso...... No significant association was found . More... | Negative | |
| Lundorf, M. D.,2005 | rs4668331 - rs769395 | GAD1 | Haplotypic associati...... Haplotypic association:in the Scottish sample set, P-value = 0.098 for BPAD. More... | No significant asso...... No significant association was found . More... | Negative | |
| Abou Jamra, R., 2010 | rs4642484 - rs9385976 - rs12214927 - rs9376659 - rs9484578 - rs6925134 | GTCTAG GTCTAG | MCHR2 | P-value = 0.0082 in ...... P-value = 0.0082 in all BPAD sample, P-value = 0.0263 in psychotic symptoms sample, P-value = 0.0244 in psychotic symptoms and male sample; global P-value = 0.0356 in all BPAS sample, global P-value = 0.0070 in psychotic symptoms sample and global P-value = 0.0226 in psychotic symptoms and male sample. More... | putative risk-haplot...... putative risk-haplotype (GTCTAG) was over-represented in all BPAD sample and psychotic symptoms sub-group. More... | Positive |
| Abou Jamra, R., 2010 | rs4642484 - rs9385976 - rs12214927 - rs9376659 - rs9484578 - rs6925134 | GTCAAG GTCAAG | MCHR2 | P-value = 0.0192 in ...... P-value = 0.0192 in all BPAD sample, P-value = 0.0128 in psychotic symptoms sample, P-value = 0.0070 in psychotic symptoms and male sample; global P-value = 0.0356 in all BPAS sample, global P-value = 0.0070 in psychotic symptoms sample and global P-value = 0.0226 in psychotic symptoms and male sample. More... | The previously detec...... The previously detected putative protective-haplotype (GTCAAG) was over-represented in all BPAD sample and psychotic symptoms sub-group. More... | Positive |
| McAuley, E. Z., 2012 | rs4586379 - rs8025225 - rs11074066 - rs11074067 - rs2035645 | T-T-A-G-T T-T-A-G-T | ST8SIA2 | P-value = 0.015, X&l...... P-value = 0.015, X<sup>2</sup>=5.91, OR (95% CI)=1.29 (1.03-1.33) in NIMH BP More... | The most common hapl...... The most common haplotype (TTAGT, equivalent to the risk haplotype identified in the Australian cohort) was significantly over represented in the NIMH bipolar disorder cases compared to controls. More... | Positive |
| McAuley, E. Z., 2012 | rs4586379 - rs8025225 - rs11074066 - rs11074067 - rs2035645 | C-C-C-C-G C-C-C-C-G | ST8SIA2 | P-value = 0.09, X<...... P-value = 0.09, X<sup>2</sup>=2.83, OR (95% CI)=0.87 (0.73-1.02) in NIMH BP More... | No significant assoc...... No significant association was reported in this study. More... | Negative |
| McAuley, E. Z., 2012 | rs4586379 - rs2035645 - rs4777974 - rs11637898 - rs11074070 - rs3784735 | A-A-G-G-A-A A-A-G-G-A-A | ST8SIA2 | P-value = 0.011, X&l...... P-value = 0.011, X<sup>2</sup>=6.46, OR (95% CI)=1.473 (1.09-1.99) in Aus BP More... | Global significant a...... Global significant association across a 6 SNP haplotype spanning 54 kb, starting 16 kb upstream of ST8SIA2 through to the middle of intron 2, was found with SNPs rs4586379, rs2035645, rs4777974, rs11637898, rs11074070 and rs3784735. The most common haplotype AAGGAA, had a higher frequency in cases than in controls constituted a putative bipolar risk haplotype. More... | Positive |
| McAuley, E. Z., 2012 | rs4586379 - rs2035645 - rs4777974 - rs11637898 - rs11074070 - rs3784735 | G-C-A-A-C-C G-C-A-A-C-C | ST8SIA2 | P-value = 0.015, X&l...... P-value = 0.015, X<sup>2</sup>=5.97, OR (95% CI)=0.5857 (0.38-0.90) in Aus BP More... | GCAACC representing ...... GCAACC representing the third most common haplotype had a higher frequency in controls than in cases, constituted a putative protective haplotype. More... | Positive |
| Lin, Y. M., 2007 | rs4570625 - rs11178997 - rs11178998 | G-T-A G-T-A | TPH2 | P-value = 0.01, OR (...... P-value = 0.01, OR (95% CI)=1.7 (1.11-2.59); Total and global P values were < 0.001 More... | Positive | |
| Lin, Y. M., 2007 | rs4570625 - rs11178997 - rs11178998 | T-A-G T-A-G | TPH2 | P-value < 0.001, ...... P-value < 0.001, OR (95% CI)=3.73 (1.89-7.36); Total and global P values were < 0.001 More... | significant differen...... significant differences in distribution between groups were detected for haplotype TAG, even after a Bonferroni correction; the TAG haplotype was associated with noteworthy risk More... | Positive |
| Lin, Y. M., 2007 | rs4570625 - rs11178997 - rs11178998 | T-A-A T-A-A | TPH2 | P-value < 0.001, ...... P-value < 0.001, OR (95% CI)=0.19 (0.08-0.46); Total and global P values were < 0.001 More... | significant differen...... significant differences in distribution between groups were detected for haplotype TAA, even after a Bonferroni correction; the TAA haplotype was with significant protective effects More... | Positive |
| Lin, Y. M., 2007 | rs4570625 - rs11178997 - rs11178998 | G-T-G G-T-G | TPH2 | P-value < 0.001; ...... P-value < 0.001; Total and global P values were < 0.001 More... | significant differen...... significant differences in distribution between groups were detected for haplotype GTG, even after a Bonferroni correction More... | Positive |
| Lin, Y. M., 2007 | rs4570625 - rs11178997 - rs11178998 | Others Others | TPH2 | P-value = 0.21, OR (...... P-value = 0.21, OR (95% CI)=0.43 (0.11-1.68); Total and global P values were < 0.001 More... | Negative | |
| Lin, Y. M., 2007 | rs4570625 - rs11178997 - rs11178998 | T-T-A T-T-A | TPH2 | P-value = 0.54, OR (...... P-value = 0.54, OR (95% CI)=0.89 (0.60-1.30); Total and global P values were < 0.001 More... | TTA haplotype was eq...... TTA haplotype was equally distributed between patients and controls More... | Negative |
| Campos, S. B., 2010 | rs4565946 - rs11179000 - rs7955501 - rs10506645 | CATT CATT | TPH2 | P-value = 0.03, OR =...... P-value = 0.03, OR = 2.162e-007 More... | The C-A-T-T haplotyp...... The C-A-T-T haplotype was significantly more frequent in patients with BD when compared with controls, but the result did not survive permutation testing. More... | Positive |
| Wen, Z., 2016 | rs4531002-rs11989919 | C-T C-T | NRG1 | P(unadj)-value=0.001...... P(unadj)-value=0.001, Bonferroni P-value=0.003, OR=1.211, 95%CI=1.076-1.363 More... | In the block rs45310...... In the block rs4531002-rs11989919, haplotype, CT, proved to be a risk factor of bipolar disorder, and global. More... | Positive |
| Wen, Z., 2016 | rs4512342-rs6982890 | T-T T-T | NRG1 | P(unadj)-value=0.019...... P(unadj)-value=0.019, Bonferroni P-value=0.057, OR=1.183, 95%CI=1.026-1.364 More... | In rs4512342-rs69828...... In rs4512342-rs6982890, there was no significant results for bipolar disorder after Bonferroni correction. More... | Negative |
| Severinsen, J. E., 2006 (b) | rs4468 - D22S1169 - D22S922 - rs132234 | BRD1 FAM19A5 | P-value = 0.7872 in ...... P-value = 0.7872 in BD, P-value = 0.1853 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs4468 - D22S1169 - D22S922 | BRD1 | P-value = 0.8753 in ...... P-value = 0.8753 in BD, P-value = 0.403 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs4468 - D22S1169 | BRD1 | P-value = 0.8945 in ...... P-value = 0.8945 in BD, P-value = 0.3317 in BD and SZ More... | Negative | ||
| Nyegaard, M., 2010 | rs4468 - rs138841 - rs138855 | TCG TCG | BRD1 | None of the 11 Seque...... None of the 11 Sequenom SNPs showed association with BPD. More... | Negative | |
| Nyegaard, M., 2010 | rs4468 rs138841 | CA CA | BRD1 | None of the 11 Seque...... None of the 11 Sequenom SNPs showed association with BPD. More... | Negative | |
| Nyegaard, M., 2010 | rs4468 rs138841 | TC TC | BRD1 | None of the 11 Seque...... None of the 11 Sequenom SNPs showed association with BPD. More... | Negative | |
| Campos, S. B., 2010 | rs4448731 - rs4565946 - rs11179000 | CCT CCT | TPH2 | P-value = 0.05; OR ...... P-value = 0.05; OR = 5.224e-008 More... | The C-C-T haplotype ...... The C-C-T haplotype occurred only in controls. But the result did not survive permutation testing. More... | Positive |
| Etain, B.,2012 | rs4446909 - rs5989681 - rs56690322 - rs6644635 | G-G-G-C G-G-G-C | ASMT | Haplotype associatio...... Haplotype association analysis:for French sample, P(value(Pperm)=0.11(0.46), OR[95%CI]=1.23[0.95-1.59]; for German sample, P(value(Pperm)=0.1(0.39), OR[95%CI]=1.17[0.97-1.41]; meta P(value=0.02, OR[95%CI]=1.19[1.03-1.38] More... | Significant associat...... Significant association was observed in BD. More... | Positive |
| Etain, B.,2012 | rs4446909 - rs5989681 - rs56690322 - rs6644635 | G-G-G-T G-G-G-T | ASMT | Haplotype associatio...... Haplotype association analysis:for French sample, P(value(Pperm)=0.33(0.85), OR[95%CI]=0.88[0.68-1.14]; for German sample, P(value(Pperm)=1(1), OR[95%CI]=1[0.83-1.21]; meta P(value=0.56, OR[95%CI]=0.96[0.82-1.11] More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Etain, B.,2012 | rs4446909 - rs5989681 - rs56690322 - rs6644635 | A-C-G-C A-C-G-C | ASMT | Haplotype associatio...... Haplotype association analysis:for French sample, P(value(Pperm)=0.007(0.03), OR[95%CI]=0.71[0.55-0.91]; for German sample, P(value(Pperm)=0.02(0.14), OR[95%CI]=0.79[0.64-0.97]; meta P(value=0.0005, OR[95%CI]=0.76[0.65-0.89] More... | Significant associat...... Significant association was observed in BD. More... | Positive |
| Etain, B.,2012 | rs4446909 - rs5989681 - rs56690322 - rs6644635 | G-G-A-T G-G-A-T | ASMT | Haplotype associatio...... Haplotype association analysis:for French sample, P(value(Pperm)=0.07(0.3), OR[95%CI]=1.43[0.98-2.09]; for German sample, P(value(Pperm)=0.48(1), OR[95%CI]=0.89[0.65-1.21]; meta P(value=0.54, OR[95%CI]=1.08[0.85-1.37] More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Etain, B.,2012 | rs4446909 - rs5989681 - rs56690322 - rs6644635 | G-C-G-C G-C-G-C | ASMT | Haplotype associatio...... Haplotype association analysis:for French sample, P(value(Pperm)=0.37(0.85), OR[95%CI]=1.24[0.77-1.99]; for German sample, P(value(Pperm)=0.06(0.36), OR[95%CI]=1.5[0.98-2.30]; meta P(value=0.05, OR[95%CI]=1.37[1.00-1.89] More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Pickard, B. S., 2006 | rs4430518 - rs433110 - rs7111184 - rs2156635 | GRIK4 | P-value = 0.904 betw...... P-value = 0.904 between SCZ cases and controls; P-value = 0.758 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs4430518 - rs433110 - rs7111184 | GRIK4 | P-value = 0.993 betw...... P-value = 0.993 between BPD cases and controls; P-value = 0.855 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs4430518 - rs433110 | GRIK4 | P-value = 0.918 betw...... P-value = 0.918 between BPD cases and controls; P-value = 0.769 between all cases and controls More... | Negative | ||
| Xu, C.,2012 | rs4375 - rs3788533 | T-C T-C | PLA2G6 | Family based study: ...... Family based study: TDT,BD,260/227(T/UT), P = 0.055 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Xu, C.,2012 | rs4375 - rs3788533 | C-G C-G | PLA2G6 | Family based study: ...... Family based study: TDT,BD,248/291(T/UT), P = 0.016,P-Bonferroni = 0.03;BD-I,212/247(T/UT), P = 0.038,P-Bonferroni = 0.076;BD-I probands with history of psychosis,120/14(T/UT)8, P = 0.041,P-Bonferroni = 0.082;BD-I probands without history of psychosis,57/69(T/UT), P = 0.133 More... | Association with BD ...... Association with BD as a whole was observed in the family study More... | Positive |
| Lyons-Warren, A.,2005 | rs435136 - hCV3259834 | C-G C-G | CIT | Haplotypic associati...... Haplotypic association:FBAT, under-transmitted, individual P-value = 0.026 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Lyons-Warren, A.,2005 | rs435136 - hCV3259834 | T-A T-A | CIT | Haplotypic associati...... Haplotypic association:FBAT, over-transmitted, individual P-value = 0.044 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Pickard, B. S., 2006 | rs433110 - rs7111184 - rs2156635 - rs949056 | GRIK4 | P-value = 0.917 betw...... P-value = 0.917 between SCZ cases and controls; P-value = 0.707 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs433110 - rs7111184 - rs2156635 | GRIK4 | P-value = 0.688 betw...... P-value = 0.688 between BPD cases and controls; P-value = 0.57 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs433110 - rs7111184 | GRIK4 | P-value = 0.988 betw...... P-value = 0.988 between BPD cases and controls; P-value = 0.606 between all cases and controls More... | Negative | ||
| Pae, C. U.,2010 | rs4305745 - rs562047 - rs452939 | TAAR6, HPS70 | Epistasis between TA...... Epistasis between TAAr6 and HSP-70 variations distinguishes BD patients from controls. CV consistency?9/10; P<0.0010; testing balancing accuracy=0.65. More... | Homozygosis of the T...... Homozygosis of the T allele at the rs4305745 was at risk of BP only when co-occurring with the homozygosis for the C allele at rs562047 and A allele at rs452939. More... | Positive | |
| Thomson, P. A., 2007 | rs4298458 - SNP8NRG241930 - SNP8NRG243177 - rs10113797 | NRG1 | P-value = 0.0269 for...... P-value = 0.0269 for BP More... | Positive | ||
| Iwayama, Y., 2010 | rs4247671 - rs12662030 - rs9372716 | AAT AAT | FABP7 | P-value = 0.047, glo...... P-value = 0.047, global P-value = 0.1940 More... | Positive | |
| Iwayama, Y., 2010 | rs4247671 - rs12662030 - rs9372716 | AAC AAC | FABP7 | P-value = 0.988, glo...... P-value = 0.988, global P-value = 0.1940 More... | Negative | |
| Iwayama, Y., 2010 | rs4247671 - rs12662030 - rs9372716 | ACC ACC | FABP7 | P-value = 0.099, glo...... P-value = 0.099, global P-value = 0.1940 More... | Negative | |
| Iwayama, Y., 2010 | rs4247671 - rs12662030 - rs9372716 | GAC GAC | FABP7 | P-value = 0.321, glo...... P-value = 0.321, global P-value = 0.1940 More... | Negative | |
| Pickard, B. S., 2006 | rs4245040 - rs7928347 - rs2000869 - rs7479743 | GRIK4 | P-value = 0.158 betw...... P-value = 0.158 between SCZ cases and controls; P-value = 0.221 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs4245040 - rs7928347 - rs2000869 | GRIK4 | P-value = 0.187 betw...... P-value = 0.187 between BPD cases and controls; P-value = 0.288 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs4245040 - rs7928347 | GRIK4 | P-value = 0.05 betwe...... P-value = 0.05 between BPD cases and controls; P-value = 0.089 between all cases and controls More... | Negative | ||
| Shi, J., 2007 | rs4151120 - rs3853818 - rs2302765 - rs2302762 - rs9217 | T-T-T-T-T T-T-T-T-T | CHRNB1 | Uncorrected P-value ...... Uncorrected P-value = 0.011, Gene-wide Permutation P-value = 0.249 More... | The haplotype showed...... The haplotype showed nominally significant association with BD by Haploview analyses but the significance did not remain after permutation testing More... | Positive |
| Lohoff, F. W., 2010 | rs3974590 - rs593713 | GA GA | MPPE1 | Chi square=6.589, P-...... Chi square=6.589, P-value = 0.01, permutation P-value = 0.0495 More... | association between ...... association between the GA haplotype and BPD. More... | Positive |
| Lohoff, F. W., 2010 | rs3974590 - rs593713 | AG AG | MPPE1 | Chi square=3.607, P-...... Chi square=3.607, P-value = 0.058, permutation P-value = 0.259 More... | Negative | |
| Lohoff, F. W., 2010 | rs3974590 - rs593713 | GG GG | MPPE1 | Chi square=0.054, P-...... Chi square=0.054, P-value = 0.816, permutation P-value = 1 More... | Negative | |
| Lohoff, F. W., 2010 | rs3974590 - rs593713 | AA AA | MPPE1 | Chi square=4.475, P-...... Chi square=4.475, P-value = 0.034, permutation P-value = 0.17 More... | Negative | |
| Schulze, T. G.,2005 | rs3918342 - rs1421292 | C-T C-T | DAOA | For Polish group :Al...... For Polish group :All Patients With Bipolar Affective Disorder, P-value > 0.05 , OR=1.16 More... | No significant asso...... No significant association was found . More... | Negative |
| Schulze, T. G.,2005 | rs3918342 - rs1421292 | T-A T-A | DAOA | For Polish group :Al...... For Polish group :All Patients With Bipolar Affective Disorder, P-value > 0.05 , OR=0.99 More... | No significant asso...... No significant association was found . More... | Negative |
| Hukic, D. S.,2013 | rs3916967 - rs2391191 - rs1935062 | C-A-C C-A-C | DAOA | BP1 CMS vs. ABD cont...... BP1 CMS vs. ABD controls: P-value = 0.14,OR[95%CI] = 0.83[0.71–1.1] More... | No significant assoc...... No significant association was observed. More... | Negative |
| Hukic, D. S.,2013 | rs3916967 - rs2391191 - rs1935062 | T-G-C T-G-C | DAOA | BP1 CMS vs. ABD cont...... BP1 CMS vs. ABD controls: P-value = 0.19,OR[95%CI] = 0.58[0.37–1.1] More... | No significant assoc...... No significant association was observed. More... | Negative |
| Hukic, D. S.,2013 | rs3916967 - rs2391191 - rs1935062 | C-A-A C-A-A | DAOA | BP1 CMS vs. ABD cont...... BP1 CMS vs. ABD controls: P-value = 0.1,OR[95%CI] = 0.65[0.47–1.0] More... | No significant assoc...... No significant association was observed. More... | Negative |
| Hukic, D. S.,2013 | rs3916967 - rs2391191 - rs1935062 | T-G-A T-G-A | DAOA | BP1 CMS vs. ABD cont...... BP1 CMS vs. ABD controls: P-value = 0.0057,OR[95%CI] = 1.41[1.1–1.6] More... | Significant associat...... Significant association was observed. More... | Positive |
| Grigoroiu-Serbanescu, M.,2010 | rs3916967 - rs2391191 | DAOA | Haplotype analysis:f...... Haplotype analysis:for non-psychotic patients, global P-value = 0.0524 (corrected value in 100, 000 permutations) More... | Significant associat...... Significant association was found in non-psychotic BP-I patients. More... | Positive | |
| Soler, J., 2016 | rs3916965 - rs3916967 - rs2391191 - rs778294 - rs3918342 - rs1421292 | G-A-G-A-C-T G-A-G-A-C-T | DAOA | P(unadj)-value=0.000...... P(unadj)-value=0.0008, OR(CI95%) = 0.39(0.23-0.69) More... | The haplotype GAGACT...... The haplotype GAGACT at DAOA was under-transmitted to patients (P = 0.0008), indicating its association with these disorders. Given that this haplotype was significantly under-transmitted to patients, it can be assumed that it confers a protective effect. More... | Positive |
| Gaysina, D.,2010 | rs3916965 - rs3741775 | DAOA DAO | Interaction analysis...... Interaction analysis:P-value = 0.048(>0.05 after correction) in the UK sample. More... | No significant asso...... No significant association was found . More... | Negative | |
| Gaysina, D.,2010 | rs3916965 - rs12584489 - rs2391191 | DAOA | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=3.08, P-value = 0.21 for UK sample; X<sup>2</sup>=0.45, P-value = 0.8 for Canadian sample. More... | No significant asso...... No significant association was found . More... | Negative | |
| Alaerts, M.,2009 | rs3813034-5 - HTTVNTR - 5HTTLPR | SLC6A4 | Global simulated P-v...... Global simulated P-value = 0.48 More... | No statistically sig...... No statistically significant association was found. More... | Negative | |
| Alaerts, M.,2009 | rs3813034-5 - HTTVNTR | SLC6A4 | Global simulated P-v...... Global simulated P-value = 0.66 More... | No statistically sig...... No statistically significant association was found. More... | Negative | |
| Alaerts, M.,2009 | rs3813034-5 - HTTLPR | SLC6A4 | Global simulated P-v...... Global simulated P-value = 0.22 More... | No statistically sig...... No statistically significant association was found. More... | Negative | |
| Severinsen, J. E., 2006 (b) | rs3810971 - rs137932 - rs137931 - rs6010260 | MOV10L1 MLC1 | P-value = 0.7716 in ...... P-value = 0.7716 in BD, P-value = 0.2924 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs3810971 - rs137932 - rs137931 | MOV10L1 MLC1 | P-value = 0.8016 in ...... P-value = 0.8016 in BD, P-value = 0.8355 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs3810971 - rs137932 | MOV10L1 MLC1 | P-value = 0.8155 in ...... P-value = 0.8155 in BD, P-value = 0.9882 in BD and SZ More... | Negative | ||
| Roche, S., 2007 | rs3804040 - rs2839350 | C-A C-A | S100B | TDT P-value = 0.096,...... TDT P-value = 0.096, X<sup>2</sup>=4.68 in BPI More... | Negative | |
| Fullerton, J. M.,2010 | rs3792797 - rs8177435 - rs5746136 - rs4880 | GPX3 SOD2 | Haplotype analysis:O...... Haplotype analysis:OR = 2.247, X<sup>2</sup> = 9.526, P-value = 0.002026, corrected P-value = 0.029 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Fullerton, J. M.,2010 | rs3792797 - rs4880 | GPX3 SOD2 | Interaction analysis...... Interaction analysis:genotype, at narrow additive interaction model (P-value = 0.008), after Bonferroni correction for multiple testing(P-value = 0.055) More... | No significant asso...... No significant association was found . More... | Negative | |
| Fukuo, Y.,2010 | rs3790757 - rs9659997 | HTR6 | Haplotype-wise analy...... Haplotype-wise analysis:global P-value = 0.687 More... | No significant asso...... No significant association was found . More... | Negative | |
| Nievergelt, C. M., 2006 | rs3789327 - rs2278749 | A-T A-T | ARNTL | phase-certain and un...... phase-certain and uncertain haplotypes: P-value associated with the haplotype=0.0005464, nominal P-value for the setting based on Chi-square test=0.00457, global permutated P-value = 0.02597, Bonferroni corrected P-value = 0.234; estimation of missing parental genotypes in addition to uncertain haplotypes: P-value associated with the haplotype=0.001395, nominal P-value for the setting based on Chi-square test=0.00379, global permutated P-value = 0.02498, Bonferroni corrected P-value = 0.225 More... | Suggestive evidence ...... Suggestive evidence for association was found in the gene ARNTL for an under-transmitted single haplotype comprised of the intronic markers 4 (rs3789327) and 5 (rs2278749) as part of the two-marker window analysis with settings 2 (PG=0.02597) and 3 (PG=0.02498), respectively. More... | Positive |
| Dmitrzak-Weglarz, M. P., 2014 | rs3789327 - rs11022778 | A-T A-T | ARNTL | BD II: Case frequenc...... BD II: Case frequency=0.626, control frequency=0.555; Chi square=4.095, P-value=0.043 More... | Significant associat...... Significant association between this block and BD was observed. More... | Positive |
| Dmitrzak-Weglarz, M. P., 2014 | rs3789327 - rs11022778 | G-G G-G | ARNTL | BD II: Case frequenc...... BD II: Case frequency=0.269, control frequency=0.289; Chi square=0.413, P-value=0.520 More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Dmitrzak-Weglarz, M. P., 2014 | rs3789327 - rs11022778 | G-T G-T | ARNTL | BD II: Case frequenc...... BD II: Case frequency=0.105, control frequency=0.155; Chi square=4.037, P-value=0.044 More... | Significant associat...... Significant association between this block and BD was observed. More... | Positive |
| Pers, T. H.,2011 | rs3761432 - rs929036 | C-G C-G | YWHAH | Haplotype analysis:f...... Haplotype analysis:for Norwegian sample, individual P-value = P=0.0036, individual P-value(permutation)=0.018; for combined sample, individual P-value = 0.027; for Danish sample, individual P-value = 0.051; for combined sample, individual P-value = 0.0084 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Pers, T. H.,2011 | rs3761432 - rs929036 | G-A G-A | YWHAH | Haplotype analysis:f...... Haplotype analysis:for Danish sample, individual P-value = 0.023; for Norwegian sample, individual P-value = 0.0013; for combined sample, individual P-value = 0.0005, individual P-value(permutation)=0.0059 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Pers, T. H.,2011 | rs3761432 - rs929036 | G-G G-G | YWHAH | Haplotype analysis:f...... Haplotype analysis:for Norwegian sample, individual P-value = 0.043 More... | Significant associat...... Significant association was found in Norwegian sample. More... | Positive |
| Pers, T. H.,2011 | rs3761432 - rs929036 | T-G T-G | YWHAH | Haplotype analysis:f...... Haplotype analysis:for Norwegian sample, individual P-value = 0.029 More... | Significant associat...... Significant association was found in Norwegian sample. More... | Positive |
| Thomson, P. A., 2007 | rs3757930 - rs10103750 - rs10503932 - rs9656744 | NRG1 | P-value = 0.0078 for...... P-value = 0.0078 for BP More... | Positive | ||
| Thomson, P. A., 2007 | rs3757930 - rs10103750 - rs10503932 | NRG1 | P-value = 0.0045 for...... P-value = 0.0045 for BP More... | Positive | ||
| Thomson, P. A., 2007 | rs3757930 - rs10103750 | NRG1 | P-value = 0.0216 for...... P-value = 0.0216 for BP More... | Positive | ||
| Schosser, A.,2011 | rs3747672 - rs9881504 | TNK2 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.175, global P-value = 0.069 More... | No significant asso...... No significant association was found . More... | Negative | |
| Schosser, A.,2011 | rs3747672 - rs745497 | TNK2 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.116, global P-value = 0.211 More... | No significant asso...... No significant association was found . More... | Negative | |
| Palo, O. M., 2007 | rs3738401 - rs1538977 | A-A A-A | DISC1 | Individual P-value =...... Individual P-value = 0.17 in all, P-value = 0.347 in males, P-value = 0.324 in females; global P-value = 0.426 in all, P-value = 0.254 in males, P-value = 0.749 in females, with bipolar spectrum disorder More... | Negative | |
| Arai, M., 2007 | rs3738398 - DISC1_-215(TG)8-13 | [G-(TG)<sub>8&...... [G-(TG)<sub>8</sub>], [G-(TG)<sub>9</sub>], [C-(TG)<sub>12</sub>] More... | DISC1 | Global P-value = 0.9...... Global P-value = 0.985 for bipolar disorder More... | No significant diffe...... No significant differences were found in the frequency of these three major haplotypes between mood disorders and control patients More... | Negative |
| Karege, F.,2010 | rs3730358 - rs1130214 - rs3803300 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.1406 More... | No significant asso...... No significant association was found . More... | Negative | |
| Karege, F.,2010 | rs3730358 - rs1130214 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.0973 More... | No significant asso...... No significant association was found . More... | Negative | |
| Shi, J., 2008 (b) | rs37022 - rs2042449 | TG TG | SLC6A3 | Gene-wide significan...... Gene-wide significant haplotypic association with bipolar disorder: TDT P-value = 0.0068, Gene-wide P-value = 0.0340 More... | Gene-wide significan...... Gene-wide significant haplotypic associations with BP, none of these associations survived correction for multiple testing More... | Positive |
| Gutierrez, B., 2007 | rs363420 - rs363343 - rs363272 | SLC18A2 | Global P-value < ...... Global P-value < E-04 More... | yielded globally sig...... yielded globally significant evidence for association in BD cases, and BD and SZ combined group More... | Positive | |
| Gutierrez, B., 2007 | rs363420 - rs363343 | SLC18A2 | Global P-value < ...... Global P-value < E-06 More... | the 2-marker haploty...... the 2-marker haplotype yielded globally significant evidence for association in BD cases and BD and SZ combined group More... | Positive | |
| Gutierrez, B., 2007 | rs363420 - rs363272 | SLC18A2 | Global P-value < ...... Global P-value < 0.0004 in BD cases; Global P-value < E-06 in BD and SZ combined group More... | the 2-marker haploty...... the 2-marker haplotype yielded globally significant evidence for association in BD cases and BD and SZ combined group More... | Positive | |
| Gutierrez, B., 2007 | rs363387 - rs363420 - rs363343 - rs363272 | SLC18A2 | Global P-value < ...... Global P-value < E-06 More... | The result revealed ...... The result revealed highly significant differences in haplotype distributions between bipolar patients and between BD and SZ combined group and controls More... | Positive | |
| Gutierrez, B., 2007 | rs363387 - rs363420 - rs363343 | SLC18A2 | Global P-value < ...... Global P-value < E-04 More... | yielded globally sig...... yielded globally significant evidence for association in BD cases, and BD and SZ combined group More... | Positive | |
| Gutierrez, B., 2007 | rs363387 - rs363420 - rs363272 | SLC18A2 | Global P-value < ...... Global P-value < E-04 More... | yielded globally sig...... yielded globally significant evidence for association in BD cases, and BD and SZ combined group More... | Positive | |
| Gutierrez, B., 2007 | rs363387 - rs363343 - rs363272 | T-A-G T-A-G | SLC18A2 | OR=4.438 (95%CI: 1.7...... OR=4.438 (95%CI: 1.78-11.06) in BD cases; OR=4.1 (95%CI: 1.83-9.21) in BD and SZ combined group; Likelihood ratio chi-squared P-value < E-06 in BD cases and in BD and SZ combined group More... | The estimation of ha...... The estimation of haplotype effects using the UNPHASED software showed an increased risk, compared to controls, for both bipolar disorder and/or schizophrenia in carriers of TAG haplotype More... | Positive |
| Gutierrez, B., 2007 | rs363387 - rs363343 - rs363272 | C-C-A C-C-A | SLC18A2 | OR=1.817 (95%CI: 0.8...... OR=1.817 (95%CI: 0.840-3.929) in BD cases; OR=2.336 (95%CI: 1.28-4.26) in BD and SZ combined group; Likelihood ratio chi-squared P-value < E-06 in BD cases and in BD and SZ combined group More... | a trend association ...... a trend association was also found for CCA combination in BD cases, which reached significance when patients with bipolar disorder and schizophrenia were grouped together More... | Positive |
| Gutierrez, B., 2007 | rs363387 - rs363343 - rs363272 | T-C-A T-C-A | SLC18A2 | Likelihood ratio chi...... Likelihood ratio chi-squared P-value < E-06 in BD cases and in BD and SZ combined group More... | significantly more c...... significantly more common among controls compared to patients' groups More... | Positive |
| Gutierrez, B., 2007 | rs363387 - rs363343 - rs363272 | C-A-G C-A-G | SLC18A2 | Likelihood ratio chi...... Likelihood ratio chi-squared P-value < E-06 in BD cases and in BD and SZ combined group More... | significantly more c...... significantly more common among controls compared to patients' groups More... | Positive |
| Etain, B., 2010 | rs362987 - rs363006 - rs1051312 - rs8636 | CACC CACC | SNAP25 | P-value = 0.04 for '...... P-value = 0.04 for 'CACC' haplotype More... | have significant P-v...... have significant P-values in early onset subgroup More... | Positive |
| Palo, O. M.,2010 | rs342296 - rs1476878 | G-G G-G | PRKAR2B | Haplotypic associati...... Haplotypic association:Z-score=2.918, FBAT P-value = 0.003 More... | Significant associat...... Significant association was found. More... | Positive |
| Lin YF, 2013 | rs334558 - rs6438552 | C-C C-C | GSK3B | no P-value no P-value | No significant assoc...... No significant association was observed. More... | Negative |
| Lin YF, 2013 | rs334558 - rs6438552 | C-T C-T | GSK3B | P-value=0.013, OR (9...... P-value=0.013, OR (95%CI)=4.18 (1.35, 12.96); adjusted P-value=0.014, OR (95%CI)=4.22 (1.34, 13.25) More... | Compared to the most...... Compared to the most frequent haplotype C-C, a rare haplotype C-T was associated with an increased risk for bipolar I disorder. However, these significant effects disappeared after FDR correction. More... | Positive |
| Lin YF, 2013 | rs334558 - rs6438552 | T-C T-C | GSK3B | P-value=0.473, OR (9...... P-value=0.473, OR (95%CI)=1.48 (0.51, 4.28); adjusted P-value=0.49, OR (95%CI)=1.46 (0.50, 4.28) More... | No significant assoc...... No significant association was observed. More... | Negative |
| Lin YF, 2013 | rs334558 - rs6438552 | T-T T-T | GSK3B | P-value=0.571, OR (9...... P-value=0.571, OR (95%CI)=0.9 (0.62, 1.30); adjusted P-value=0.57, OR (95%CI)=0.9 (0.55, 1.47) More... | No significant assoc...... No significant association was observed. More... | Negative |
| Thomson, P. A., 2007 | rs327329 - rs7007662 - rs1481762 - rs726908 | NRG1 | P-value = 0.0072 for...... P-value = 0.0072 for BP More... | Positive | ||
| Thomson, P. A., 2007 | rs327329 - rs7007662 - rs1481762 | NRG1 | P-value = 0.0299 for...... P-value = 0.0299 for BP More... | Positive | ||
| Gaysina, D.,2009 | rs3213207 - rs1011313 - rs760761 | DTNBP1 | Three Marker Haploty...... Three Marker Haplotype Sliding-Window Analysis:Global P-value = 0.1, Individual P-value = 0.04 More... | No statistically sig...... No statistically significant association was found. More... | Negative | |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-C-G-C-A A-C-G-C-A | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.88, X<sup>2</sup>=0.02; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-T-G-C-A A-T-G-C-A | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.05, X<sup>2</sup>=3.69; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-C-A-T-C A-C-A-T-C | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.12, X<sup>2</sup>=2.45; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-C-A-C-A A-C-A-C-A | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.77, X<sup>2</sup>=0.08; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-C-G-T-A A-C-G-T-A | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.00016, X<sup>2</sup>=14.2; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups, in particular due to the protective effect of the A-C-G-T-A haplotype More... | Positive |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-C-A-C-C A-C-A-C-C | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.06, X<sup>2</sup>=3.59; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-C-G-T-C A-C-G-T-C | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.08, X<sup>2</sup>=3.1; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | G-C-A-T-C G-C-A-T-C | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.36, X<sup>2</sup>=0.82; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-C-G-C-C A-C-G-C-C | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.49, X<sup>2</sup>=0.47; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-T-A-C-A A-T-A-C-A | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.85, X<sup>2</sup>=0.03; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-T-G-T-A A-T-G-T-A | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.14, X<sup>2</sup>=2.2; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-C-A-T-A A-C-A-T-A | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.15, X<sup>2</sup>=2.05; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | G-C-A-C-C G-C-A-C-C | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.24, X<sup>2</sup>=1.38; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | G-C-G-T-C G-C-G-T-C | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.31, X<sup>2</sup>=1.05; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-T-G-C-C A-T-G-C-C | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.72, X<sup>2</sup>=0.12; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | G-T-A-C-C G-T-A-C-C | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.36, X<sup>2</sup>=0.84; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | G-C-G-C-C G-C-G-C-C | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.44, X<sup>2</sup>=0.6; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | G-C-A-T-A G-C-A-T-A | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.46, X<sup>2</sup>=0.54; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | G-T-G-C-A G-T-G-C-A | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 0.46, X<sup>2</sup>=0.54; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Pae, C. U., 2007 (a) | rs3213207 - rs1011313 - rs2005976 - rs760761 - rs2619522 | A-T-A-C-C A-T-A-C-C | DTNBP1 | COCAPHASE P-value = ...... COCAPHASE P-value = 1, X<sup>2</sup>=0.01; global P-value = 0.009, X<sup>2</sup>=36.5237, df=19 More... | haplotype distributi...... haplotype distribution was different between the two groups More... | Negative |
| Fullerton, J. M.,2010 | rs3170633 - rs2301022 | C-T C-T | GCLM | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>= 3.82, individual P-value = 0.050, OR = 1.293 for narrow model. More... | No significant asso...... No significant association was found . More... | Negative |
| Pickard, B. S., 2006 | rs3133855 - rs3133226 - rs2187495 - rs3132780 | GRIK4 | P-value = 0.594 betw...... P-value = 0.594 between SCZ cases and controls; P-value = 0.824 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs3133855 - rs3133226 - rs2187495 | GRIK4 | P-value = 0.485 betw...... P-value = 0.485 between BPD cases and controls; P-value = 0.885 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs3133855 - rs3133226 | GRIK4 | P-value = 0.957 betw...... P-value = 0.957 between BPD cases and controls; P-value = 0.971 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs3133226 - rs2187495 - rs3132780 - rs948028 | GRIK4 | P-value = 0.503 betw...... P-value = 0.503 between SCZ cases and controls; P-value = 0.597 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs3133226 - rs2187495 - rs3132780 | GRIK4 | P-value = 0.326 betw...... P-value = 0.326 between BPD cases and controls; P-value = 0.564 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs3133226 - rs2187495 | GRIK4 | P-value = 0.179 betw...... P-value = 0.179 between BPD cases and controls; P-value = 0.492 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs3132780 - rs948028 - rs2852217 - rs879602 | GRIK4 | P-value = 0.022 betw...... P-value = 0.022 between SCZ cases and controls; P-value = 0.171 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs3132780 - rs948028 - rs2852217 | GRIK4 | P-value = 0.54 betwe...... P-value = 0.54 between BPD cases and controls; P-value = 0.543 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs3132780 - rs948028 | GRIK4 | P-value = 0.954 betw...... P-value = 0.954 between BPD cases and controls; P-value = 0.779 between all cases and controls More... | Negative | ||
| Kandaswamy, R.,2012 | rs3128296 - rs3128309 | PRKCZ | Association analysis...... Association analysis:chi square=6.53, P-value = 0.016 More... | Significant associat...... Significant association was observed in BD. More... | Positive | |
| Kandaswamy, R.,2012 | rs3128296 - rs2503706 - rs3128309 | PRKCZ | Association analysis...... Association analysis:chi square=8.48, P-value = 0.004 More... | Significant associat...... Significant association was observed in BD. More... | Positive | |
| Kandaswamy, R.,2012 | rs3128296 - rs2503706 | PRKCZ | Association analysis...... Association analysis:chi square=8.20, P-value = 0.009 More... | Significant associat...... Significant association was observed in BD. More... | Positive | |
| McAuley, E. Z.,2009 | rs3125 - rs6314 - rs1923886 - rs2224721 - rs2770296 | HTR2A | haplotype analysis:g...... haplotype analysis:global P-value = 0.03; (C-C-G-C-A):P-value = 0.02, OR=0.63; (C-C-A-C-G):P-value = 0.007, OR=3.08 More... | We detected signific...... We detected significant associations in BP group. More... | Positive | |
| Zandi, P. P., 2007 | rs2945733 - rs2978033 - rs1554325 | ST3GAL1 | P-value = 0.0009 P-value = 0.0009 | a three-SNP haplotyp...... a three-SNP haplotype in the 5' region of ST3GAL1 (rs2945733-rs2978033-rs1554325) was associated at P=0.0009 More... | Positive | |
| Thomson, P. A., 2007 | rs2919390 - rs6988339 - rs3757930 - rs10103750 | NRG1 | P-value = 0.0019 for...... P-value = 0.0019 for BP, P-value = 0.0001 for SCZ and BP More... | Positive | ||
| Thomson, P. A., 2007 | rs2919390 - rs6988339 - rs3757930 | NRG1 | P-value = 0.0022 for...... P-value = 0.0022 for BP, P-value = 0.0001 for SCZ and BP More... | the most significant...... the most significant haplotype in SCZ was also nominally significant in the BP sample; this was the only haplotype to withstand permutation analysis in this study, identifying a new region of association with both schizophrenia and the combined case group in the Scottish population More... | Positive | |
| Walker, R. M.,2010 | rs2919390 - rs6988339 - rs3757930 | NRG1 | Haplotypic associati...... Haplotypic association:P-value = 0.0022 for Scottish 1, P-value = 0.24 for German More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Thomson, P. A., 2007 | rs2919390 - rs6988339 | NRG1 | P-value = 0.0143 for...... P-value = 0.0143 for BP, P-value = 0.0008 for SCZ and BP More... | Positive | ||
| Walker, R. M.,2010 | rs2919390 - rs6988339 | NRG1 | Haplotypic associati...... Haplotypic association:P-value = 0.014 for Scottish 1, P-value = 0.12 for German More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Lohoff, F. W., 2008 (a) | rs2856966 - rs928978 - rs2231187 | 1-1-1 (1=major alle...... 1-1-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1, X<sup>2&...... OR=1, X<sup>2</sup>=0.06, P-value =0.793 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs2856966 - rs928978 - rs2231187 | 1-1-2 (1=major alle...... 1-1-2 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=0.99, X<sup>...... OR=0.99, X<sup>2</sup>=0.01, P-value =0.896 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs2856966 - rs928978 - rs2231187 | 1-2-1 (1=major alle...... 1-2-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1.29, X<sup>...... OR=1.29, X<sup>2</sup>=1, P-value =0.315 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs2856966 - rs928978 - rs2231187 | 2-2-1 (1=major alle...... 2-2-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=0.6, X<sup>...... OR=0.6, X<sup>2</sup>=2.18, P-value =0.139 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Szczepankiewicz, A., 2013 | rs28536160 - rs28373064 - rs35369693 | A-G-G A-G-G | AVPR1B | P-value=0.556, X<...... P-value=0.556, X<sup>2</sup>=0.345 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz, A., 2013 | rs28536160 - rs28373064 - rs35369693 | G-G-G G-G-G | AVPR1B | P-value=0.352, X<...... P-value=0.352, X<sup>2</sup>=0.865 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz, A., 2013 | rs28536160 - rs28373064 - rs35369693 | G-C-A G-C-A | AVPR1B | P-value=0.561, X<...... P-value=0.561, X<sup>2</sup>=0.337 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz, A., 2013 | rs28536160 - rs28373064 - rs35369693 | G-G-A G-G-A | AVPR1B | P-value=0.36, X<s...... P-value=0.36, X<sup>2</sup>=0.837 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Pickard, B. S., 2006 | rs2852217 - rs879602 - rs1954787 - rs4935752 | GRIK4 | P-value = 0.12 betwe...... P-value = 0.12 between SCZ cases and controls; P-value = 0.041 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs2852217 - rs879602 - rs1954787 | GRIK4 | P-value = 0.035 betw...... P-value = 0.035 between BPD cases and controls; P-value = 0.039 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs2852217 - rs879602 | GRIK4 | P-value = 0.034 betw...... P-value = 0.034 between BPD cases and controls; P-value = 0.232 between all cases and controls More... | Positive | ||
| Lohoff, F. W., 2008 (a) | rs2846811 - rs8192595 - rs2856966 | 1-1-1 (1=major alle...... 1-1-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1, X<sup>2&...... OR=1, X<sup>2</sup>=0.01, P-value =0.943 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs2846811 - rs8192595 - rs2856966 | 1-1-2 (1=major alle...... 1-1-2 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=0.92, X<sup>...... OR=0.92, X<sup>2</sup>=0.14, P-value =0.707 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs2846811 - rs8192595 - rs2856966 | 2-1-1 (1=major alle...... 2-1-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1.11, X<sup>...... OR=1.11, X<sup>2</sup>=0.12, P-value =0.729 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Roche, S., 2007 | rs2839363 - rs3788266 | G-A(BPI)/G-G(BPI&...... G-A(BPI)/G-G(BPI&psychosis) More... | S100B | TDT P-value = 0.075,...... TDT P-value = 0.075, X<sup>2</sup>=6.906 in BPI, TDT P-value = 0.025, X<sup>2</sup>=9.329 in BPI and psychosis More... | haplotypes comprised...... haplotypes comprised of alleles from M8 and M9 were now significantly associated in BPI and psychosis More... | Positive |
| Roche, S., 2007 | rs2839359 - rs2839363 | T-A T-A | S100B | TDT P-value = 0.85, ...... TDT P-value = 0.85, X<sup>2</sup>=0.795 in BPI More... | Negative | |
| Roche, S., 2007 | rs2839355 - rs2839359 | T-T T-T | S100B | TDT P-value = 0.608,...... TDT P-value = 0.608, X<sup>2</sup>=1.834 in BPI More... | Negative | |
| Roche, S., 2007 | rs2839351 - rs9722 | C-C C-C | S100B | TDT P-value = 0.047,...... TDT P-value = 0.047, X<sup>2</sup>=7.953 in BPI More... | A sliding window hap...... A sliding window haplotype analysis also revealed borderline evidence for association of haplotypes comprised of alleles from M3 and M4 with BPAD More... | Positive |
| Roche, S., 2007 | rs2839350 - rs2839351 | A-C A-C | S100B | TDT P-value = 0.095,...... TDT P-value = 0.095, X<sup>2</sup>=4.701 in BPI More... | Negative | |
| Kakiuchi, C., 2007 (b) | rs283525 - rs8647 - rs8667 | ATF5 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.4183 in Japanese samples; TDT P-value = 0.565 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Kakiuchi, C., 2007 (b) | rs283525 - rs8647 | ATF5 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.5999 in Japanese samples; TDT P-value = 0.565 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Kakiuchi, C., 2007 (b) | rs283524 - rs283525 - rs8647 - rs8667 | ATF5 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.4648 in Japanese samples; TDT P-value = 0.06708 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Kakiuchi, C., 2007 (b) | rs283524 - rs283525 - rs8647 | ATF5 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.4337 in Japanese samples; TDT P-value = 0.067 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Kakiuchi, C., 2007 (b) | rs283524 - rs283525 | ATF5 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.3844 in Japanese samples; TDT P-value = 0.2365 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Ram Murthy, A., 2012 | rs2812393 - rs821616 | C-A C-A | DISC1 | P-value=0.088 for BP...... P-value=0.088 for BPAD, P-value=0.125 for combined cases, P-value=0.172 for BPAD females, P-value=0.077 for combined females, P-value=0.268 for BPAD males, P-value=0.673 for combined males More... | Negative | |
| Ram Murthy, A., 2012 | rs2812393 - rs821616 | G-A G-A | DISC1 | P-value=0.699 for BP...... P-value=0.699 for BPAD, P-value=0.806 for combined cases, P-value=0.729 for BPAD females, P-value=0.834 for combined females, P-value=0.859 for BPAD males, P-value=0.898 for combined males More... | Negative | |
| Ram Murthy, A., 2012 | rs2812393 - rs821616 | G-T G-T | DISC1 | P-value=0.017 for BP...... P-value=0.017 for BPAD, P-value=0.001 for combined cases, P-value=0.035 for BPAD females, P-value=0.005 for combined females, P-value=0.193 for BPAD males, P-value=0.039 for combined males More... | Allelic combinations...... Allelic combinations of G-T in SCZ (P=0), combined cases of BPAD or SCZ (P=0.001), SCZ females (P=0.007) and combined females (P=0.005) were observed to be protective combination of alleles. These combinations survived multiple corrections. In addition allelic combinations of G-T showed nominal significance, but did not withstand FDR corrections. More... | Positive |
| Ram Murthy, A., 2012 | rs2812393 - rs821616 | C-T C-T | DISC1 | P-value=0.799 for BP...... P-value=0.799 for BPAD, P-value=0.531 for combined cases, P-value=0.752 for BPAD females, P-value=0.642 for combined females, P-value=0.537 for BPAD males, P-value=0.206 for combined males More... | Negative | |
| Thomson, P. A.,2005(a) | rs2812393 - rs1322784 - rs2759346 - rs6675281 | TSNAX DISC1 | Global association t...... Global association test:for BP, P-value = 0.096(all), 0.12(male), 0.26(female); More... | No significant asso...... No significant association was found . More... | Negative | |
| Thomson, P. A.,2005(a) | rs2812393 - rs1322784 | C-C C-C | TSNAX DISC1 | Global association t...... Global association test:for BP, P-value = 0.023(all), 0.32(male), 0.034(female); More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Lyons-Warren, A.,2005 | rs278109 - rs203368 - rs435136 - hCV3259834 | A-G-T-A A-G-T-A | CIT | Haplotypic associati...... Haplotypic association:FBAT, over-transmitted, individual P-value = 0.065 More... | No significant asso...... No significant association was found . More... | Negative |
| Lyons-Warren, A.,2005 | rs278109 - rs203368 | G-A G-A | CIT | Haplotypic associati...... Haplotypic association:FBAT, under-transmitted, individual P-value = 0.049 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Xiao, Y.,2011 | rs2738864 - rs16841582 | C-C C-C | DISC1 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.0191 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Hodgkinson, C. A., 2007 | rs2702009 - rs559668 - rs597570 - rs10893385 - rs1365410 - rs12223186 - rs2241514 - rs2907228 - rs10893380 | 1-1-1-2-2-2-2-1-2 1-1-1-2-2-2-2-1-2 | FEZ1 | P-value = 0.618 in C...... P-value = 0.618 in Caucasians More... | No association was f...... No association was found in either population between specific haplotypes and any of the psychiatric disorders. More... | Negative |
| Hodgkinson, C. A., 2007 | rs2702009 - rs559668 - rs597570 - rs10893385 - rs1365410 - rs12223186 - rs2241514 - rs2907228 - rs10893380 | 1-2-2-1-2-2-2-1-2 1-2-2-1-2-2-2-1-2 | FEZ1 | P-value = 0.248 in C...... P-value = 0.248 in Caucasians More... | No association was f...... No association was found in either population between specific haplotypes and any of the psychiatric disorders. More... | Negative |
| Hodgkinson, C. A., 2007 | rs2702009 - rs559668 - rs597570 - rs10893385 - rs1365410 - rs12223186 - rs2241514 - rs2907228 - rs10893380 | 1-2-2-1-2-1-1-1-2 1-2-2-1-2-1-1-1-2 | FEZ1 | P-value = 0.292 in C...... P-value = 0.292 in Caucasians More... | No association was f...... No association was found in either population between specific haplotypes and any of the psychiatric disorders. More... | Negative |
| Hodgkinson, C. A., 2007 | rs2702009 - rs559668 - rs597570 - rs10893385 - rs1365410 - rs12223186 - rs2241514 - rs2907228 - rs10893380 | 2-2-2-2-2-2-2-1-2 2-2-2-2-2-2-2-1-2 | FEZ1 | P-value = 0.525 in C...... P-value = 0.525 in Caucasians More... | No association was f...... No association was found in either population between specific haplotypes and any of the psychiatric disorders. More... | Negative |
| Hodgkinson, C. A., 2007 | rs2702009 - rs559668 - rs597570 - rs10893385 - rs1365410 - rs12223186 - rs2241514 - rs2907228 - rs10893380 | 2-2-2-2-2-2-2-2-1 2-2-2-2-2-2-2-2-1 | FEZ1 | P-value = 0.999 in C...... P-value = 0.999 in Caucasians More... | No association was f...... No association was found in either population between specific haplotypes and any of the psychiatric disorders. More... | Negative |
| Raybould, R.,2005 | rs2619539 - rs3213207 - rs2619538 | DTNBP1 | Haplotypic associati...... Haplotypic association:in BPI, for risk/protective/other, global P-value = 0.420; for six haplotypes, global P-value = 0.076; in BPI with Psychotic Symptoms in 50% or More of Episodes, for risk/protective/other, global P-value = 0.042; for six haplotypes, global P-value = 0.079 More... | No significant asso...... No significant association was found . More... | Negative | |
| Gaysina, D.,2009 | rs2619539 - rs3213207 - rs1011313 | DTNBP1 | Three Marker Haploty...... Three Marker Haplotype Sliding-Window Analysis:Global P-value = 0.09, Individual P-value = 0.011 More... | No statistically sig...... No statistically significant association was found. More... | Negative | |
| Joo, E. J., 2007 | rs2619538 - rs2619522 - rs760761 | DTNBP1 | P-value = 0.049 for ...... P-value = 0.049 for BPD I, P-value = 0.268 for BPD I and II, P-value = 0.478 for BPD I, II and SA More... | The haplotypic assoc...... The haplotypic association was lost when included P1320 in a haplotype More... | Negative | |
| Joo, E. J., 2007 | rs2619538 - rs2619522 | DTNBP1 | P-value = 0.026 for ...... P-value = 0.026 for BPD I, P-value = 0.154 for BPD I and II, P-value = 0.311 for BPD I, II and SA More... | A positive associati...... A positive association was observed between the SNP A-P1763 haplotype and the bipolar I phenotype. This haplotypic association was lost when we broadened the phenotype to include bipolar II and schizoaffective disorder. More... | Positive | |
| Breen, G., 2006 | rs2619522 - rs760761 - rs2619528 | T-C-G T-C-G | DTNBP1 | P-value = 0.03, Z=-2...... P-value = 0.03, Z=-2.11 More... | It is one of the mos...... It is one of the most significant 3-marker haplotypes and empirical p values. More... | Positive |
| Breen, G., 2006 | rs2619522 - rs760761 - rs2619528 | G-T-A G-T-A | DTNBP1 | P-value = 0.03, Z=1....... P-value = 0.03, Z=1.73 More... | It is one of the mos...... It is one of the most significant 3-marker haplotypes and empirical p values. More... | Positive |
| Breen, G., 2006 | rs2619522 - rs760761 - rs2005976 - rs2619528 | T-C-G-G T-C-G-G | DTNBP1 | P-value = 0.028, Z=-...... P-value = 0.028, Z=-2.19 More... | It is one of the mos...... It is one of the most significant 3-marker haplotypes and empirical p values. The 4-5-6-7 haplotype was positive with a significance of p=0.005. More... | Positive |
| Breen, G., 2006 | rs2619522 - rs760761 - rs2005976 - rs2619528 | G-T-A-A G-T-A-A | DTNBP1 | P-value = 0.08, Z=1....... P-value = 0.08, Z=1.73 More... | It is one of the mos...... It is one of the most significant 3-marker haplotypes and empirical p values. The 4-5-6-7 haplotype was positive with a significance of p=0.005. More... | Negative |
| Breen, G., 2006 | rs2619522 - rs760761 - rs2005976 | T-C-G T-C-G | DTNBP1 | P-value = 0.03, Z=-2...... P-value = 0.03, Z=-2.07 More... | It is one of the mos...... It is one of the most significant 3-marker haplotypes and empirical p values. More... | Positive |
| Breen, G., 2006 | rs2619522 - rs760761 - rs2005976 | G-T-A G-T-A | DTNBP1 | P-value = 0.03, Z=1....... P-value = 0.03, Z=1.6 More... | It is one of the mos...... It is one of the most significant 3-marker haplotypes and empirical p values. More... | Positive |
| Joo, E. J., 2007 | rs2619522 - rs760761 | DTNBP1 | P-value = 0.311 for ...... P-value = 0.311 for BPD I, P-value = 0.603 for BPD I and II, P-value = 0.838 for BPD I, II and SA More... | a significant haplot...... a significant haplotype association was not found in P1763-P1320 More... | Negative | |
| Lohoff, F. W.,2005(b) | rs2565055 - rs2565065 - rs891398 - rs735421 - rs2292977 - rs748281 | G-A-T-A-G-C G-A-T-A-G-C | CHRNA2 | Haplotypic associati...... Haplotypic association:OR=0.924, X<sup>2</sup>=0.562, Individual P-value = 0.4532 More... | No significant asso...... No significant association was found . More... | Negative |
| Lohoff, F. W.,2005(b) | rs2565055 - rs2565065 - rs891398 - rs735421 - rs2292977 - rs748281 | G-G-C-A-C-T G-G-C-A-C-T | CHRNA2 | Haplotypic associati...... Haplotypic association:OR=1, X<sup>2</sup>=0.002, Individual P-value = 0.9621 More... | No significant asso...... No significant association was found . More... | Negative |
| Lohoff, F. W.,2005(b) | rs2565055 - rs2565065 - rs891398 - rs735421 - rs2292977 - rs748281 | G-G-C-A-G-C G-G-C-A-G-C | CHRNA2 | Haplotypic associati...... Haplotypic association:OR=1.727, X<sup>2</sup>=1.454, Individual P-value = 0.2278 More... | No significant asso...... No significant association was found . More... | Negative |
| Lohoff, F. W.,2005(b) | rs2565055 - rs2565065 - rs891398 - rs735421 - rs2292977 - rs748281 | G-G-C-G-G-C G-G-C-G-G-C | CHRNA2 | Haplotypic associati...... Haplotypic association:OR=0.721, X<sup>2</sup>=2.433, Individual P-value = 0.1188 More... | No significant asso...... No significant association was found . More... | Negative |
| Lohoff, F. W.,2005(b) | rs2565055 - rs2565065 - rs891398 - rs735421 - rs2292977 - rs748281 | G-G-T-A-G-C G-G-T-A-G-C | CHRNA2 | Haplotypic associati...... Haplotypic association:OR=1, X<sup>2</sup>=0.005, Individual P-value = 0.9424 More... | No significant asso...... No significant association was found . More... | Negative |
| Lohoff, F. W.,2005(b) | rs2565055 - rs2565065 - rs891398 - rs735421 - rs2292977 - rs748281 | T-G-C-A-G-C T-G-C-A-G-C | CHRNA2 | Haplotypic associati...... Haplotypic association:OR=1.844, X<sup>2</sup>=2.986, Individual P-value = 0.0839 More... | No significant asso...... No significant association was found . More... | Negative |
| Lohoff, F. W.,2005(b) | rs2565055 - rs2565065 - rs891398 - rs735421 - rs2292977 - rs748281 | T-G-C-G-G-C T-G-C-G-G-C | CHRNA2 | Haplotypic associati...... Haplotypic association:OR=1.188, X<sup>2</sup>=0.992, Individual P-value = 0.3192 More... | No significant asso...... No significant association was found . More... | Negative |
| Kandaswamy, R.,2012 | rs2503706 - rs3128309 | PRKCZ | Association analysis...... Association analysis:chi square=7.57, P-value = 0.008 More... | Significant associat...... Significant association was observed in BD. More... | Positive | |
| Karege, F.,2010 | rs2498804 - rs2494732 - rs1130233 - rs3730358 - rs1130214 - rs3803300 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.046 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Karege, F.,2010 | rs2498804 - rs2494732 - rs1130233 - rs3730358 - rs1130214 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.159 More... | No significant asso...... No significant association was found . More... | Negative | |
| Karege, F.,2010 | rs2498804 - rs2494732 - rs1130233 - rs3730358 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.0643 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Karege, F.,2010 | rs2498804 - rs2494732 - rs1130233 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.0366 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Karege, F.,2010 | rs2498804 - rs2494732 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.0438 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Karege, F.,2010 | rs2494732 - rs1130233 - rs3730358 - rs1130214 - rs3803300 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.026 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Karege, F.,2010 | rs2494732 - rs1130233 - rs3730358 - rs1130214 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.0275 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Karege, F.,2010 | rs2494732 - rs1130233 - rs3730358 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.1034 More... | No significant asso...... No significant association was found . More... | Negative | |
| Karege, F.,2010 | rs2494732 - rs1130233 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.0728 More... | No significant asso...... No significant association was found . More... | Negative | |
| Schosser, A., 2010 | rs2492367 - rs6675281 - rs12133766 | TCG TCG | DISC1 | Individual P-value =...... Individual P-value = 0.05, global P-value = 0.3 More... | Negative | |
| Schosser, A., 2010 | rs2492367 - rs6675281 | TC TC | DISC1 | Individual P-value =...... Individual P-value = 0.03, global P-value = 0.14 More... | Positive | |
| Thomson, P. A.,2005(a) | rs2492367 - rs2812393 - rs1322784 - rs2759346 | TSNAX DISC1 | Global association t...... Global association test:for BP, P-value = 0.13(all), 0.2(male), 0.26(female); More... | No significant asso...... No significant association was found . More... | Negative | |
| Thomson, P. A.,2005(a) | rs2492367 - rs2812393 - rs1322784 | C-C-C C-C-C | TSNAX DISC1 | Global association t...... Global association test:for BP, P-value = 0.0068(all), 0.28(male), 0.024(female); More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Thomson, P. A.,2005(a) | rs2492367 - rs2812393 - rs1322784 | C-G-T C-G-T | TSNAX DISC1 | Global association t...... Global association test:for BP, individual P-value = 0.0063(all), individual P-value = 0.0079(female) More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Kishi, T., 2008 (a) | rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 | PAWR | Global P-value = 0.1...... Global P-value = 0.158 for bipolor disorder More... | Negative | ||
| Kishi, T., 2008 (a) | rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 | GAGTA GAGTA | PAWR | P-value = 0.109 for ...... P-value = 0.109 for bipolor disorder More... | Negative | |
| Kishi, T., 2008 (a) | rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 | GAACG GAACG | PAWR | P-value = 0.229 for ...... P-value = 0.229 for bipolor disorder More... | Negative | |
| Kishi, T., 2008 (a) | rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 | ATGCA ATGCA | PAWR | P-value = 0.994 for ...... P-value = 0.994 for bipolor disorder More... | Negative | |
| Kishi, T., 2008 (a) | rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 | GAGCG GAGCG | PAWR | P-value = 0.423 for ...... P-value = 0.423 for bipolor disorder More... | Negative | |
| Kishi, T., 2008 (a) | rs2463169 - rs2400546 - rs17005769 - rs4842318 - rs7305141 | AAGCA AAGCA | PAWR | P-value = 0.0720 for...... P-value = 0.0720 for bipolor disorder More... | Negative | |
| Shi, J., 2008 (c) | rs2452594 - rs1543013 | GA GA | PDLIM5 | Association analysis...... Association analysis showed TDT P-value = 0.47 More... | Negative | |
| Shi, J., 2008 (c) | rs2452594 - rs1543013 | AC AC | PDLIM5 | Association analysis...... Association analysis showed TDT P-value = 0.70 More... | Negative | |
| Shi, J., 2008 (c) | rs2452594 - rs1543013 | GC GC | PDLIM5 | Association analysis...... Association analysis showed TDT P-value = 0.70 More... | Negative | |
| Thomson, P. A., 2007 | rs2439305 - rs2439300 - rs2439286 - rs10095694 | NRG1 | P-value = 0.0098 for...... P-value = 0.0098 for SZ and BP combined More... | Positive | ||
| Thomson, P. A., 2007 | rs2439300 - rs2439286 - rs10095694 - rs2919390 | NRG1 | P-value = 0.0097 for...... P-value = 0.0097 for SZ and BP combined More... | Positive | ||
| Thomson, P. A., 2007 | rs2439286 - rs10095694 - rs2919390 - rs6988339 | NRG1 | P-value = 0.0074 for...... P-value = 0.0074 for BP, P-value = 0.0002 for SCZ and BP More... | Positive | ||
| Thomson, P. A., 2007 | rs2439286 - rs10095694 - rs2919390 | NRG1 | P-value = 0.0224 for...... P-value = 0.0224 for BP, P-value = 0.0017 for SCZ and BP More... | Positive | ||
| Thomson, P. A., 2007 | rs2439286 - rs10095694 | NRG1 | P-value = 0.0274 for...... P-value = 0.0274 for BP, P-value = 0.0028 for SCZ and BP More... | Positive | ||
| Cao L., 2014 | rs2439273 - rs6468121 - rs2466044 - rs3808368 - rs2976521 | A-A-A-T-G A-A-A-T-G | NRG1 | Globe: X<sup>2...... Globe: X<sup>2</sup>=24.95, Bonf P-value=0.047; A-A-A-T-G: X<sup>2</sup>=14.31, Bonf P-value=0.021 More... | likely supporting th...... likely supporting the association between this NRG1 region and BPI. More... | Positive |
| Cao L., 2014 | rs2439273 - rs6468121 - rs2466044 | A-A-A A-A-A | NRG1 | Globe: X<sup>2...... Globe: X<sup>2</sup>=22.75, Bonf P-value=0.019; A-A-A: X<sup>2</sup>=16.2, Bonf P-value=0.008 More... | All of these haploty...... All of these haplotypes were more common in controls than in BPI patients, suggesting that its presence might indicate a decreased risk of BPI. More... | Positive |
| Cao L., 2014 | rs2439273 - rs6468121 | A-A A-A | NRG1 | Globe: X<sup>2...... Globe: X<sup>2</sup>=18.97, Bonf P-value=0.010; A-A: X<sup>2</sup>=16.51, Bonf P-value=0.007 More... | All of these haploty...... All of these haplotypes were more common in controls than in BPI patients, suggesting that its presence might indicate a decreased risk of BPI. More... | Positive |
| Zhao, T.,2009 | rs2433322 - rs2438146 | A-C A-C | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.010(after Bonferroni correction), Individual P-value = 0.003, OR (95% CI)=0.67(0.51-0.87) More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhao, T.,2009 | rs2433322 - rs2438146 | G-C G-C | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.006(after Bonferroni correction), Individual P-value < 0.001, Individual P-value = 0.005(after Bonferroni correction), OR (95% CI)=2.95(1.68-5.20) More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhao, T.,2009 | rs2433320 - rs2433322 - rs2438146 | G-A-C G-A-C | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.004(after Bonferroni correction), Individual P-value = 0.01, OR (95% CI)=0.68(0.51-0.91) More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhao, T.,2009 | rs2433320 - rs2433322 - rs2438146 | G-G-C G-G-C | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.004(after Bonferroni correction), Individual P-value < 0.001, Individual P-value = 0.001(after Bonferroni correction), OR (95% CI)=8.27(2.55-26.79) More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhao, T.,2009 | rs2433320 - rs2433322 | A-A A-A | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.006(after Bonferroni correction), Individual P-value = 0.05, OR (95% CI)=0.53(0.28-1.01) More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Zhao, T.,2009 | rs2433320 - rs2433322 | G-A G-A | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.006(after Bonferroni correction), Individual P-value = 0.029, OR (95% CI)=0.76(0.59-0.97) More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Zhao, T.,2009 | rs2433320 - rs2433322 | G-G G-G | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.006(after Bonferroni correction), Individual P-value < 0.001, Individual P-value = 0.007(after Bonferroni correction), OR (95% CI)=3.95(1.85-8.44) More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Squassina, A.,2008 | rs2433320 - rs2433322 | PDLIM5 | Global P-value = 0.2...... Global P-value = 0.255 More... | No association was f...... No association was found More... | Negative | |
| Squassina, A.,2008 | rs2433320 - rs2433322 | A-G A-G | PDLIM5 | X<sup>2</su...... X<sup>2</sup>=1.45; P-value = 0.23 More... | Negative | |
| Squassina, A.,2008 | rs2433320 - rs2433322 | G-A G-A | PDLIM5 | X<sup>2</su...... X<sup>2</sup>=1.18; P-value = 0.28 More... | Negative | |
| Gaysina, D.,2010 | rs2391191 - rs9558562 - rs1935062 | DAOA | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=2.55, P-value = 0.47 for UK sample; X<sup>2</sup>=1.63, P-value = 0.65 for Canadian sample. More... | No significant asso...... No significant association was found . More... | Negative | |
| Muller, D. J.,2011 | rs2391191 - rs1935062 - rs947267 - rs778294 | A-C-T-C A-C-T-C | DAOA | FBAT:for total sampl...... FBAT:for total sample, variance of the S-statistic=48.1, Z-score=-2.67, P-value = 0.008, global P-value = 0.14; for European sample, variance of the S-statistic=44.9, Z-score=-3.13, P-value = 0.002, global P-value = 0.05 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Muller, D. J.,2011 | rs2391191 - rs1935062 - rs947267 | A-C-T A-C-T | DAOA | FBAT:for total sampl...... FBAT:for total sample, variance of the S-statistic=48, Z-score=-2.67, P-value = 0.008, global P-value = 0.25; for European sample, variance of the S-statistic=44.7, Z-score=-3.13, P-value = 0.002, global P-value = 0.06 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Muller, D. J.,2011 | rs2391191 - rs1935062 | A-C A-C | DAOA | FBAT:for total sampl...... FBAT:for total sample, variance of the S-statistic=53.1, Z-score=-2.37, P-value = 0.02, global P-value = 0.07; for European sample, variance of the S-statistic=49.9, Z-score=-2.8, P-value = 0.005, global P-value = 0.03 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Schosser, A.,2011 | rs2341399 - rs9311 | WDR53 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.977, global P-value = 0.688 More... | No significant asso...... No significant association was found . More... | Negative | |
| Abou Jamra, R, 2008 (a) | rs2306987 - rs1298865 - rs10009030 - rs2637777 - rs2304865 | CD36 | global P-value = 0....... global P-value = 0.000018 (0.00028 after correction for multiple testing of all marker combinations of the block according to Becker et al.). More... | Positive | ||
| Abou Jamra, R, 2008 (a) | rs2306987 - rs1298865 - rs10009030 - rs2637777 - rs2304865 | AGAGC AGAGC | CD36 | haplotype AGAGC (35 ...... haplotype AGAGC (35 vs 30% in controls, P-value = 0.029, OR= 1.62). More... | Haplotype AGAGC is o...... Haplotype AGAGC is overrepresented in patients. More... | Positive |
| Abou Jamra, R, 2008 (a) | rs2306987 - rs1298865 - rs10009030 - rs2637777 - rs2304865 | TACTG TACTG | CD36 | haplotype TACTG (59 ...... haplotype TACTG (59 vs 66% in controls, P-value of 0.001, OR of 0.72). More... | The opposite haploty...... The opposite haplotype, TACTG, is significantly underrepresented in the patients. More... | Positive |
| Abou Jamra, R, 2008 (a) | rs2306987 - rs1298865 - rs10009030 - rs2637777 - rs2304865 | TGCGG TGCGG | CD36 | haplotype TGCGG (3 v...... haplotype TGCGG (3 vs 1% in controls) and shows a P-value = 0.003, OR= 2.04) More... | The less frequent ha...... The less frequent haplotype TGCGG is significantly overrepresented in patients. More... | Positive |
| Blair, I. P., 2006 | rs2304865 - rs2637777 - rs2306990 - rs1298865 - rs2306987 | G-T-G-T-A G-T-G-T-A | CD36 | P-value = 0.045 P-value = 0.045 | The GTGTA haplotype ...... The GTGTA haplotype is over-represented among cases. More... | Positive |
| Blair, I. P., 2006 | rs2304865 - rs2637777 - rs2306990 - rs1298865 - rs2306987 | C-G-A-C-T C-G-A-C-T | CD36 | P-value = 0.012 P-value = 0.012 | The CGACT haplotype ...... The CGACT haplotype is under-represented among cases. More... | Positive |
| Li, X.,2009 | rs2290279 - rs510110 | NAPG | haplotype frequencie...... haplotype frequencies in bipolar patients and controls:Global P-value = 0.008892, Most associated individual haplotype:A-A, Individual P-value = 0.004488 More... | We detected signific...... We detected significant associations in BP group. More... | Positive | |
| Li, X.,2009 | rs2290279 - rs495484 - rs510110 | NAPG | haplotype frequencie...... haplotype frequencies in bipolar patients and controls:Global P-value = 0.013, Most associated individual haplotype:A-T-A, Individual P-value = 0.004929 More... | We detected signific...... We detected significant associations in BP group. More... | Positive | |
| Li, X.,2009 | rs2290279 - rs495484 | NAPG | haplotype frequencie...... haplotype frequencies in bipolar patients and controls:Global P-value = 0.003584, Most associated individual haplotype:A-T, Individual P-value = 0.00254 More... | We detected signific...... We detected significant associations in BP group. More... | Positive | |
| Nievergelt, C. M., 2006 | rs228729 - rs228642 - rs228666 - rs228696 - rs2859388 - rs11576985 | C-T-C-C-A-4 C-T-C-C-A-4 | PER3 | phase-certain haplot...... phase-certain haplotypes: P-value associated with the haplotype=0.00385, nominal P-value for the setting based on Chi-square test=0.00965, global permutated P-value = 0.01898, Bonferroni corrected P-value = 0.171; phase-certain and uncertain haplotypes: P-value associated with the haplotype=0.01241, nominal P-value for the setting based on Chi-square test=0.00804, global permutated P-value = 0.00799, Bonferroni corrected P-value = 0.072; estimation of missing parental genotypes in addition to uncertain haplotypes: P-value associated with the haplotype=0.0148, nominal P-value for the setting based on Chi-square test=0.02103, global permutated P-value = 0.03596, Bonferroni corrected P-value = 0.324 More... | Suggestive evidence ...... Suggestive evidence for association was found in the four, five, and six marker window analyses in all three analysis settings, with one under-transmitted haplotype and one to two overtransmitted haplotypes. The strongest evidence was found on haplotypes including all six markers (PG=0.00799) and was almost reaching Bonferroni-corrected significance (PGC=0.072). More... | Positive |
| Nievergelt, C. M., 2006 | rs228729 - rs228642 - rs228666 - rs228696 - rs2859388 - rs11576985 | C-C-C-C-G-4 C-C-C-C-G-4 | PER3 | phase-certain haplot...... phase-certain haplotypes: P-value associated with the haplotype=0.008638; phase-certain and uncertain haplotypes: P-value associated with the haplotype=0.01036; estimation of missing parental genotypes in addition to uncertain haplotypes: P-value associated with the haplotype=0.03067 More... | Suggestive evidence ...... Suggestive evidence for association was found in the four, five, and six marker window analyses in all three analysis settings, with one under-transmitted haplotype and one to two overtransmitted haplotypes. More... | Positive |
| Nievergelt, C. M., 2006 | rs228729 - rs228642 - rs228666 - rs228696 - rs2859388 - rs11576985 | T-C-T-C-A-5 T-C-T-C-A-5 | PER3 | phase-certain haplot...... phase-certain haplotypes: P-value associated with the haplotype=0.1755; phase-certain and uncertain haplotypes: P-value associated with the haplotype=0.01516; estimation of missing parental genotypes in addition to uncertain haplotypes: P-value associated with the haplotype=0.0293 More... | Suggestive evidence ...... Suggestive evidence for association was found in the four, five, and six marker window analyses in all three analysis settings, with one under-transmitted haplotype and one to two overtransmitted haplotypes. More... | Positive |
| Nievergelt, C. M., 2006 | rs228666 - rs228696 - rs2859388 - rs11576985 | C-C-A-4 C-C-A-4 | PER3 | phase-certain haplot...... phase-certain haplotypes: P-value associated with the haplotype=0.002118, nominal P-value for the setting based on Chi-square test=0.00759, global permutated P-value = 0.03197, Bonferroni corrected P-value = 0.288 More... | Suggestive evidence ...... Suggestive evidence for association was found in the four, five, and six marker window analyses in all three analysis settings, with one under-transmitted haplotype and one to two overtransmitted haplotypes. More... | Positive |
| Nievergelt, C. M., 2006 | rs228666 - rs228696 - rs2859388 - rs11576985 | C-C-G-4 C-C-G-4 | PER3 | phase-certain haplot...... phase-certain haplotypes: P-value associated with the haplotype=0.031 More... | Suggestive evidence ...... Suggestive evidence for association was found in the four, five, and six marker window analyses in all three analysis settings, with one under-transmitted haplotype and one to two overtransmitted haplotypes. More... | Positive |
| Nievergelt, C. M., 2006 | rs228642 - rs228666 - rs228696 - rs2859388 - rs11576985 | T-C-C-A-4 T-C-C-A-4 | PER3 | phase-certain haplot...... phase-certain haplotypes: P-value associated with the haplotype=0.003858, nominal P-value for the setting based on Chi-square test=0.0144, global permutated P-value = 0.04895, Bonferroni corrected P-value = 0.441; phase-certain and uncertain haplotypes: P-value associated with the haplotype=0.01645, nominal P-value for the setting based on Chi-square test=0.00958, global permutated P-value = 0.03097, Bonferroni corrected P-value = 0.279 More... | Suggestive evidence ...... Suggestive evidence for association was found in the four, five, and six marker window analyses in all three analysis settings, with one under-transmitted haplotype and one to two overtransmitted haplotypes. More... | Positive |
| Nievergelt, C. M., 2006 | rs228642 - rs228666 - rs228696 - rs2859388 - rs11576985 | C-C-C-G-4 C-C-C-G-4 | PER3 | phase-certain haplot...... phase-certain haplotypes: P-value associated with the haplotype=0.008638; phase-certain and uncertain haplotypes: P-value associated with the haplotype=0.01037 More... | Suggestive evidence ...... Suggestive evidence for association was found in the four, five, and six marker window analyses in all three analysis settings, with one under-transmitted haplotype and one to two overtransmitted haplotypes. More... | Positive |
| Nievergelt, C. M., 2006 | rs228642 - rs228666 - rs228696 - rs2859388 - rs11576985 | C-T-C-A-5 C-T-C-A-5 | PER3 | phase-certain and un...... phase-certain and uncertain haplotypes: P-value associated with the haplotype=0.01517 More... | Suggestive evidence ...... Suggestive evidence for association was found in the four, five, and six marker window analyses in all three analysis settings, with one under-transmitted haplotype and one to two overtransmitted haplotypes. More... | Positive |
| Lyons-Warren, A.,2005 | rs2285595 - rs278109 - rs203368 - rs435136 - hCV3259834 | T-A-G-T-A T-A-G-T-A | CIT | Haplotypic associati...... Haplotypic association:FBAT, over-transmitted, individual P-value = 0.053 More... | No significant asso...... No significant association was found . More... | Negative |
| Chen, P.,2011 | rs2284031 - rs909486 - rs738149 | C-T-A C-T-A | CSF2RB | Haplotype analysis:f...... Haplotype analysis:for BPAD, P-value > 0.05 More... | No significant assoc...... No significant association was observed in BPAD. More... | Negative |
| Chen, P.,2011 | rs2284031 - rs909486 - rs738149 | C-T-G C-T-G | CSF2RB | Haplotype analysis:f...... Haplotype analysis:for BPAD, P-value > 0.05 More... | No significant assoc...... No significant association was observed in BPAD. More... | Negative |
| Chen, P.,2011 | rs2284031 - rs909486 - rs738149 | T-C-A T-C-A | CSF2RB | Haplotype analysis:f...... Haplotype analysis:for BPAD, P-value > 0.05 More... | No significant assoc...... No significant association was observed in BPAD. More... | Negative |
| Chen, P.,2011 | rs2284031 - rs909486 - rs738149 | T-C-G T-C-G | CSF2RB | Haplotype analysis:f...... Haplotype analysis:for BPAD, P-value > 0.05 More... | No significant assoc...... No significant association was observed in BPAD. More... | Negative |
| Jan, W. C., 2014 | rs2284017 - rs2284018 - rs5750285 | A-G-G A-G-G | CACNG2 | 12.5% in BP-I cases ...... 12.5% in BP-I cases vs.10.4% in controls, 19.2% in BP-II cases vs.10.5% in controls. The haplotype had grequency greater than 0.01. More... | Only one LD block in...... Only one LD block in CACNG2 were found (formed by rs2284017-rs2284018- rs5750285) in which three haplotypes had frequency greater than 0.01. Consistent with single marker analysis, haplotype AGG showed similar association with BP-I (12.5% in cases vs. 10.4% in controls), and BP-II (19.2% in cases vs. 10.5% in controls). More... | Positive |
| Pickard, B. S., 2006 | rs2282586 - rs1944522 | GRIK4 | P-value = 0.002 betw...... P-value = 0.002 between BPD cases and controls; P-value = 0.048 between all cases and controls More... | These positionally b...... These positionally bi-partite findings were further supported by a sliding window global analysis of haplotypes of lengths two to four, such that distinct clusters of significant P-values were observed in bipolar disorder (best global haplotype, SNPs 26 and 27; P = 0.002). The global haplotype approached significance after permutation analysis (P = 0.049, s.e. 0.007). More... | Positive | |
| Pickard, B. S., 2006 | rs2282586 - rs1944522 | G-C G-C | GRIK4 | P-value = 0.0002, Co...... P-value = 0.0002, Correction P-value = 0.0190 More... | a two-SNP haplotype ...... a two-SNP haplotype (GC, SNPs 26 and 27) showed the greatest significance (P = 0.0002, est. freq. cases: 0.16, est. freq. controls: 0.23, OR of 0.624 (95% CI 0.485-0.802)). This haplotype remained significant after permutation correction (P = 0.0190, s.e. 0.0043; Table 3). More... | Positive |
| Mansour, H. A., 2006 | rs2279665 - rs774026 - rs2291738 - rs2291739 | TIMELESS | global tests, P-valu...... global tests, P-value = 0.02, X<sup>2</sup>=9.62, df=3 More... | For TIMELESS, these ...... For TIMELESS, these analyses revealed over-transmission of haplotypes encompassing four SNPs rs2279665, rs774026, rs2291738 and rs2291739. Global tests of haplotypes involving these SNPs revealed a significant association. More... | Positive | |
| Iwayama, Y., 2010 | rs2279382 - rs2279381 - rs7752838 | TCA TCA | FABP7 | P-value = 0.902, glo...... P-value = 0.902, global P-value = 0.0322, Permutation global P-value = 0.0323 More... | Negative | |
| Iwayama, Y., 2010 | rs2279382 - rs2279381 - rs7752838 | TCG TCG | FABP7 | P-value = 0.009, glo...... P-value = 0.009, global P-value = 0.0322, Permutation global P-value = 0.0323, OR (95% CI)=0.82(0.71-0.95) More... | is over-represented ...... is over-represented in the control group and even after correction for multiple testing by permutation tests. More... | Positive |
| Iwayama, Y., 2010 | rs2279382 - rs2279381 - rs7752838 | GTG GTG | FABP7 | P-value = 0.546, glo...... P-value = 0.546, global P-value = 0.0322, Permutation global P-value = 0.0323 More... | Negative | |
| Iwayama, Y., 2010 | rs2279382 - rs2279381 - rs7752838 | GCG GCG | FABP7 | P-value = 0.017, glo...... P-value = 0.017, global P-value = 0.0322, Permutation global P-value = 0.0323, OR(95% CI)=1.19(1.03-1.36) More... | is over-represented ...... is over-represented in the disease group and even after correction for multiple testing by permutation tests. More... | Positive |
| Abou Jamra, R, 2008 (b) | rs2278637 - rs8067606 | VAMP2 | For initial sample, ...... For initial sample, corrected global P-value = 0.013, the strongest association was obtained for the haplotype G-A at markers rs2278637-rs8067606, which occurred with a frequency of 35.8% in patients and 29.2% in controls. For replication sample, global P-value = 0.018, haplotype G-G (at rs2278637-rs8067606), which showed opposite tendencies in the initial sample. The former observed risk-haploypte G-A at the same marker combination occurred more frequently in controls (34.0%) compared with the patients (31.9%) in the replication sample. For combined sample, global P-value = 0.252 More... | none of the analyses...... none of the analyses in our stratified subsamples showed any significant differences between cases and controls More... | Positive | |
| Pickard, B. S., 2006 | rs2276319 - rs513548 - rs2282586 - rs1944522 | GRIK4 | P-value = 0.015 betw...... P-value = 0.015 between SCZ cases and controls; P-value = 0.113 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs2276319 - rs513548 - rs2282586 - rs1944522 | A-T-G-C A-T-G-C | GRIK4 | P-value = 0.0035 P-value = 0.0035 | Positive | |
| Pickard, B. S., 2006 | rs2276319 - rs513548 - rs2282586 | GRIK4 | P-value = 0.039 betw...... P-value = 0.039 between BPD cases and controls; P-value = 0.186 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs2276319 - rs513548 - rs2282586 | A-T-G A-T-G | GRIK4 | P-value = 0.004 P-value = 0.004 | Positive | |
| Pickard, B. S., 2006 | rs2276319 - rs513548 | GRIK4 | P-value = 0.402 betw...... P-value = 0.402 between BPD cases and controls; P-value = 0.472 between all cases and controls More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs2272843 - rs3810971 - rs137932 - rs137931 | MOV10L1 MLC1 | P-value = 0.3263 in ...... P-value = 0.3263 in BD, P-value = 0.4295 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs2272843 - rs3810971 - rs137932 | MOV10L1 MLC1 | P-value = 0.328 in B...... P-value = 0.328 in BD, P-value = 0.4691 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs2272843 - rs3810971 | MOV10L1 | P-value = 0.1395 in ...... P-value = 0.1395 in BD, P-value = 0.1966 in BD and SZ More... | Negative | ||
| Yoshimi, A., 2008 | rs2271309 - rs12601930 - rs907094 - rs3764352 | PPP1R1B | Global P-value = 0.0...... Global P-value = 0.030 More... | Haplotypic analyses ...... Haplotypic analyses of four SNPs in a sample set showed that PPP1R1B polymorphisms were significantly associated with BD. More... | Positive | |
| Geller, B., 2008 | rs2241165 - BDNF_Val66Met | GAD1 BDNF | no P-value given in ...... no P-value given in the original article More... | No significant inter...... No significant interaction was found between the GAD1 and BDNF alleles in this sample. More... | Negative | |
| Severinsen, J. E., 2006 (b) | rs2239848 - rs138855 - rs4468 - D22S1169 | BRD1 | P-value = 0.5517 in ...... P-value = 0.5517 in BD, P-value = 0.263 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs2239848 - rs138855 - rs4468 | BRD1 | P-value = 0.1742 in ...... P-value = 0.1742 in BD, P-value = 0.2092 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs2239848 - rs138855 | BRD1 | P-value = 0.5005 in ...... P-value = 0.5005 in BD, P-value = 0.6658 in BD and SZ More... | Negative | ||
| Roche, S., 2007 | rs2238725 - rs2010779 | TRPM2 | TDT P-value = 0.715,...... TDT P-value = 0.715, X<sup>2</sup>=1.358 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| Roche, S., 2007 | rs2238724 - rs2238725 | TRPM2 | TDT P-value = 0.145,...... TDT P-value = 0.145, X<sup>2</sup>=3.867 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| Fatjo-Vilas, M., 2016 | rs2208870 - rs12333117 | G-C G-C | NRN1 | P(unadj)-value=0.037 P(unadj)-value=0.037 | The frenquency of th...... The frenquency of the haplotype G-C and haplotype C-C was signigicantly increased in patients than in controls. More... | Negative |
| Pickard, B. S., 2006 | rs2187495 - rs3132780 - rs948028 - rs2852217 | GRIK4 | P-value = 0.723 betw...... P-value = 0.723 between SCZ cases and controls; P-value = 0.774 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs2187495 - rs3132780 - rs948028 | GRIK4 | P-value = 0.459 betw...... P-value = 0.459 between BPD cases and controls; P-value = 0.508 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs2187495 - rs3132780 | GRIK4 | P-value = 0.312 betw...... P-value = 0.312 between BPD cases and controls; P-value = 0.495 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs2156635 - rs949056 - rs949054 - rs602104 | GRIK4 | P-value = 0.311 betw...... P-value = 0.311 between SCZ cases and controls; P-value = 0.117 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs2156635 - rs949056 - rs949054 | GRIK4 | P-value = 0.446 betw...... P-value = 0.446 between BPD cases and controls; P-value = 0.129 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs2156635 - rs949056 | GRIK4 | P-value = 0.269 betw...... P-value = 0.269 between BPD cases and controls; P-value = 0.027 between all cases and controls More... | Positive | ||
| Goes, F. S., 2009 | rs2129533 - rs716144 - rs4317533 - rs10503906 | G-G-G-G G-G-G-G | NRG1 | Haplotype Associatio...... Haplotype Association:FBAT:individual P-value = 0.01(Standard BP), 0.0067(Psychotic BP), 0.5923(Mood-incongruent psychotic BP); global P-value = 0.0225(Standard BP), 0.0068(Psychotic BP), 0.2486(Mood-incongruent psychotic BP) More... | Association was obse...... Association was observed in both standard BP and Psychotic BP. More... | Positive |
| Ross, K. A.,2011 | rs2122231 - rs9551988 | PSPC1 | SNP interactions:P-v...... SNP interactions:P-value = 0.35 More... | No significant asso...... No significant association was found . More... | Negative | |
| Ross, K. A.,2011 | rs2122231 - rs4850057 | SNP interactions:P-v...... SNP interactions:P-value = 0.42 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Ross, K. A.,2011 | rs2122231 - (SNP A-1797773) | SNP interactions:P-v...... SNP interactions:P-value = 0.82 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Prata, D., 2008 | rs2111902 - rs3918346 - rs3916972 | DAO | Global X<sup>2...... Global X<sup>2</sup>=15.22, df=6, P-value = 0.02. More... | We found haplotype w...... We found haplotype wise associations with bipolar disorder for both genes. These included a two-SNP haplotype in DAO and a two- SNPhaplotype forDAOA. More... | Positive | |
| Prata, D., 2008 | rs2111902 - rs3918346 - rs3916972 | 2-2-1: A-T-A 2-2-1: A-T-A | DAO | Z-score=3.08, P-valu...... Z-score=3.08, P-value = 0.002 More... | We found haplotype w...... We found haplotype wise associations with bipolar disorder for both genes. These included a two-SNP haplotype in DAO and a two- SNPhaplotype forDAOA. More... | Positive |
| Prata, D., 2008 | rs2111902 - rs3918346 - rs3741775 | DAO | Global X<sup>2...... Global X<sup>2</sup>=16.76, df=7, P-value = 0.01. More... | We found haplotype w...... We found haplotype wise associations with bipolar disorder for both genes. These included a two-SNP haplotype in DAO and a two- SNPhaplotype forDAOA. More... | Positive | |
| Prata, D., 2008 | rs2111902 - rs3918346 - rs3741775 | 2-2-1: A-T-T 2-2-1: A-T-T | DAO | Z-score=3.05, P-valu...... Z-score=3.05, P-value = 0.002 More... | We found haplotype w...... We found haplotype wise associations with bipolar disorder for both genes. These included a two-SNP haplotype in DAO and a two- SNPhaplotype forDAOA. More... | Positive |
| Prata, D., 2008 | rs2111902 - rs3918346 | DAO | Global X<sup>2...... Global X<sup>2</sup>=14.94, df=3, P-value = 0.003. More... | We found haplotype w...... We found haplotype wise associations with bipolar disorder for both genes. These included a two-SNP haplotype in DAO and a two- SNPhaplotype forDAOA. More... | Positive | |
| Prata, D., 2008 | rs2111902 - rs3918346 | 2-2: A-T 2-2: A-T | DAO | Z-score=3.07, P-valu...... Z-score=3.07, P-value = 0.002 More... | We found haplotype w...... We found haplotype wise associations with bipolar disorder for both genes. These included a two-SNP haplotype in DAO and a two- SNPhaplotype forDAOA. More... | Positive |
| Roche, S., 2007 | rs2096860 - rs9984977 | TRPM2 | TDT P-value = 0.562,...... TDT P-value = 0.562, X<sup>2</sup>=1.152 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| McQuillin, A.,2009 | rs208294 - rs504677 - rs2230912 | P2RX7 | Haplotypic associati...... Haplotypic association:Global LRT=14.96, df=7, Global empirical P-value = 0.029 More... | Significant associat...... Significant association with BPD was found. More... | Positive | |
| McQuillin, A.,2009 | rs208293 - rs504677 - rs2230912 - rs11065501 | P2RX7 | Haplotypic associati...... Haplotypic association:Global LRT=28.04, df=15, Global empirical P-value = 0.011 More... | Significant associat...... Significant association with BPD was found. More... | Positive | |
| McQuillin, A.,2009 | rs208293 - rs504677 - rs1718119 - rs2230912 - rs11065501 | P2RX7 | Haplotypic associati...... Haplotypic association:Global LRT=42.66, df=22, Global empirical P-value = 0.0041 More... | Significant associat...... Significant association with BPD was found. More... | Positive | |
| Barden, N., 2006 | rs208293 - rs208294 - rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 | C-C-C-A-G-C-A C-C-C-A-G-C-A | P2RX7 | chi-square P-value =...... chi-square P-value = 0.523, LRS (global P-value)=0.0178 with a sliding window strategy More... | The 7-SNP positively...... The 7-SNP positively associated haplotype window bordered by P2RX7-I04B and P2RX7-E13A overlaps blocks 1 and 2 and is characterized by a haplotype strictly observed in the case group (P-value = 0.0006) bearing the mutated allele for the non-synonymous SNP P2RX7-E08A. More... | Negative |
| Barden, N., 2006 | rs208293 - rs208294 - rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 | C-C-C-G-G-C-A C-C-C-G-G-C-A | P2RX7 | chi-square P-value =...... chi-square P-value = 0.864, LRS (global P-value)=0.0178 with a sliding window strategy More... | The 7-SNP positively...... The 7-SNP positively associated haplotype window bordered by P2RX7-I04B and P2RX7-E13A overlaps blocks 1 and 2 and is characterized by a haplotype strictly observed in the case group (P-value = 0.0006) bearing the mutated allele for the non-synonymous SNP P2RX7-E08A. More... | Negative |
| Barden, N., 2006 | rs208293 - rs208294 - rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 | C-T-C-A-G-C-A C-T-C-A-G-C-A | P2RX7 | chi-square P-value =...... chi-square P-value = 0.911, LRS (global P-value)=0.0178 with a sliding window strategy More... | The 7-SNP positively...... The 7-SNP positively associated haplotype window bordered by P2RX7-I04B and P2RX7-E13A overlaps blocks 1 and 2 and is characterized by a haplotype strictly observed in the case group (P-value = 0.0006) bearing the mutated allele for the non-synonymous SNP P2RX7-E08A. More... | Negative |
| Barden, N., 2006 | rs208293 - rs208294 - rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 | C-T-C-G-G-C-A C-T-C-G-G-C-A | P2RX7 | chi-square P-value =...... chi-square P-value = 0.959, LRS (global P-value)=0.0178 with a sliding window strategy More... | The 7-SNP positively...... The 7-SNP positively associated haplotype window bordered by P2RX7-I04B and P2RX7-E13A overlaps blocks 1 and 2 and is characterized by a haplotype strictly observed in the case group (P-value = 0.0006) bearing the mutated allele for the non-synonymous SNP P2RX7-E08A. More... | Negative |
| Barden, N., 2006 | rs208293 - rs208294 - rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 | C-T-C-G-G-G-A C-T-C-G-G-G-A | P2RX7 | chi-square P-value =...... chi-square P-value = 0.391, LRS (global P-value)=0.0178 with a sliding window strategy More... | The 7-SNP positively...... The 7-SNP positively associated haplotype window bordered by P2RX7-I04B and P2RX7-E13A overlaps blocks 1 and 2 and is characterized by a haplotype strictly observed in the case group (P-value = 0.0006) bearing the mutated allele for the non-synonymous SNP P2RX7-E08A. More... | Negative |
| Barden, N., 2006 | rs208293 - rs208294 - rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 | C-T-T-G-A-C-G C-T-T-G-A-C-G | P2RX7 | chi-square P-value =...... chi-square P-value = 0.824, LRS (global P-value)=0.0178 with a sliding window strategy More... | The 7-SNP positively...... The 7-SNP positively associated haplotype window bordered by P2RX7-I04B and P2RX7-E13A overlaps blocks 1 and 2 and is characterized by a haplotype strictly observed in the case group (P-value = 0.0006) bearing the mutated allele for the non-synonymous SNP P2RX7-E08A. More... | Negative |
| Barden, N., 2006 | rs208293 - rs208294 - rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 | T-C-C-A-G-C-A T-C-C-A-G-C-A | P2RX7 | chi-square P-value =...... chi-square P-value = 0.0006, LRS (global P-value)=0.0178 with a sliding window strategy More... | The 7-SNP positively...... The 7-SNP positively associated haplotype window bordered by P2RX7-I04B and P2RX7-E13A overlaps blocks 1 and 2 and is characterized by a haplotype strictly observed in the case group (P-value = 0.0006) bearing the mutated allele for the non-synonymous SNP P2RX7-E08A. More... | Positive |
| Barden, N., 2006 | rs208293 - rs208294 - rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 | T-C-T-G-A-C-A T-C-T-G-A-C-A | P2RX7 | chi-square P-value =...... chi-square P-value = 0.06, LRS (global P-value)=0.0178 with a sliding window strategy More... | The 7-SNP positively...... The 7-SNP positively associated haplotype window bordered by P2RX7-I04B and P2RX7-E13A overlaps blocks 1 and 2 and is characterized by a haplotype strictly observed in the case group (P-value = 0.0006) bearing the mutated allele for the non-synonymous SNP P2RX7-E08A. More... | Negative |
| Barden, N., 2006 | rs208293 - rs208294 - rs504677 - rs7958311 - rs1718119 - rs6489795 - rs2230912 | T-C-T-G-A-C-G T-C-T-G-A-C-G | P2RX7 | chi-square P-value =...... chi-square P-value = 0.048, LRS (global P-value)=0.0178 with a sliding window strategy More... | The 7-SNP positively...... The 7-SNP positively associated haplotype window bordered by P2RX7-I04B and P2RX7-E13A overlaps blocks 1 and 2 and is characterized by a haplotype strictly observed in the case group (P-value = 0.0006) bearing the mutated allele for the non-synonymous SNP P2RX7-E08A. More... | Positive |
| McQuillin, A.,2009 | rs208293 - rs1718119 - rs2230912 - rs11065501 | P2RX7 | Haplotypic associati...... Haplotypic association:Global LRT=29.02, df=13, Global empirical P-value = 0.0037 More... | Significant associat...... Significant association with BPD was found. More... | Positive | |
| Etain, B., 2010 | rs2076239 - rs362987 - rs363006 - rs1051312 | ACAC ACAC | SNAP25 | P-value = 0.06 for '...... P-value = 0.06 for 'ACAC' haplotype More... | non-significant in e...... non-significant in early onset subgroup More... | Negative |
| Verma, R.,2005(b) | rs2076127 - ss16339182 | A-T A-T | MLC1 | Haplotypic associati...... Haplotypic association:for BPAD, global P-value > 0.05, individual P-value > 0.05, odds ratio=1.03, 95%CI=0.69-1.54 More... | No significant asso...... No significant association was found . More... | Negative |
| Verma, R.,2005(b) | rs2076127 - ss16339182 | G-C G-C | MLC1 | Haplotypic associati...... Haplotypic association:for BPAD, global P-value > 0.05, individual P-value = 0.02, odds ratio=1.62, 95%CI=1.09-2.41 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Verma, R.,2005(b) | rs2076127 - ss16339182 | G-T G-T | MLC1 | Haplotypic associati...... Haplotypic association:for BPAD, global P-value > 0.05, individual P-value > 0.05, odds ratio=0.73, 95%CI=0.53-1.02 More... | No significant asso...... No significant association was found . More... | Negative |
| Gonzalez, R., 2015 | rs2075983 - rs1534891 - rs6001093 - rs135757 | A-A-G-A A-A-G-A | CSNK1E | P-value=5.91E-03 P-value=5.91E-03 | The whole marker per...... The whole marker permutation test of the CSNK1E haploblock was significantly associated with BD. More... | Positive |
| Ohnishi, T., 2007 | rs2075824 - IMPA2_-207T>C | IMPA2 | P-value = 0.033 P-value = 0.033 | displayed evidence o...... displayed evidence of association with bipolar illness More... | Positive | |
| Ancin, I.,2011(b) | rs2075507 - rs4680 - rs165599 | A-A-G A-A-G | COMT | Haplotype analysis:O...... Haplotype analysis:OR=2.96; P-value = 0.001; P-value < 0.05 after correction for multiple testing. More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Thomson, P. A.,2005(b) | rs2072621 - rs13440581 | GPR50 | Haplotypic associati...... Haplotypic association:, for BPAD, P-value = 0.51(all), 0.99(female), for BPADtBPspec, P-value = 0.099(female) More... | No significant asso...... No significant association was found . More... | Negative | |
| Thomson, P. A.,2005(b) | rs2072621 - (GPR50_502-505) - rs13440581 | GPR50 | Haplotypic associati...... Haplotypic association:, for BPAD, P-value = 0.13(all), 0.94(female), for BPADtBPspec, P-value = 0.0026(female) More... | Association was not ...... Association was not observed in BPAD but was observed in BPAD+Bpspec(female). More... | Negative | |
| Thomson, P. A.,2005(b) | rs2072621 - (GPR50_502-505) | GPR50 | Haplotypic associati...... Haplotypic association:, for BPAD, P-value = 0.017(all), 0.87(female), for BPADtBPspec, P-value = 0.00023(female) More... | Association was obse...... Association was observed in BPAD and BPAD+Bpspec(female). More... | Positive | |
| Goldstein, I.,2009 | rs2070704 - rs2295623 | ATP1A2 | multimarker associat...... multimarker association analysis:P-value = 0.0918 after Permutation test More... | This haplotype block...... This haplotype block in the ATP1A2 gene (rs2070704 -rs2295623) was significantly associated with BD . More... | Positive | |
| Feng, Y., 2008 | rs2059588 - rs1110306 - rs3784406 | NTRK3 | Global X<sup>2...... Global X<sup>2</sup>=12.924, df=7, p=0.074. For haplotypes with frequencies greater than 10%, X<sup>2</sup>=6.617, df=2, p=0.037. More... | Positive | ||
| Feng, Y., 2008 | rs2059588 - rs1110306 - rs3784406 | TGT TGT | NTRK3 | haplotype TGT P-valu...... haplotype TGT P-value = 0.037, X<sup>2</sup>(df=1)=4.335 More... | haplotype with frequ...... haplotype with frequency greater than 10% was biased in transmission More... | Positive |
| Feng, Y., 2008 | rs2059588 - rs1110306 - rs3784406 | CAG CAG | NTRK3 | haplotype CAG P-valu...... haplotype CAG P-value = 0.011, X<sup>2</sup>(df=1)=6.440 More... | haplotype with frequ...... haplotype with frequency greater than 10% was biased in transmission More... | Positive |
| Palo, O. M.,2010 | rs2056865 - rs41736 | G-G G-G | MET | Haplotypic associati...... Haplotypic association:Z-score=0.826, FBAT P-value = 0.408 More... | No significant asso...... No significant association was found . More... | Negative |
| Lyons-Warren, A.,2005 | rs203368 - rs435136 - hCV3259834 | A-C-G A-C-G | CIT | Haplotypic associati...... Haplotypic association:FBAT, under-transmitted, individual P-value = 0.041 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Lyons-Warren, A.,2005 | rs203368 - rs435136 - hCV3259834 | G-T-A G-T-A | CIT | Haplotypic associati...... Haplotypic association:FBAT, over-transmitted, individual P-value = 0.031 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Lyons-Warren, A.,2005 | rs203368 - rs435136 | A-C A-C | CIT | Haplotypic associati...... Haplotypic association:FBAT, under-transmitted, individual P-value = 0.014 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Lyons-Warren, A.,2005 | rs203368 - rs435136 | G-T G-T | CIT | Haplotypic associati...... Haplotypic association:FBAT, over-transmitted, individual P-value = 0.011 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Palo, O. M.,2010 | rs2028030 - rs916691 | A-A A-A | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=-0.967, FBAT P-value = 0.333 More... | No significant asso...... No significant association was found . More... | Negative |
| Ikeda, M., 2006 | rs2020934 - SLC6A4_5HTTVNTR - rs3813034 | SLC6A4 | global P-value = 0.9...... global P-value = 0.903 More... | We found no associat...... We found no association with BP in the haplotype-wise association analysis. More... | Negative | |
| Ikeda, M., 2006 | rs2020934 - SLC6A4_5HTTVNTR | SLC6A4 | global P-value = 0.9...... global P-value = 0.910 More... | We found no associat...... We found no association with BP in the haplotype-wise association analysis. More... | Negative | |
| Roche, S., 2007 | rs2010779 - rs6518189 | TRPM2 | TDT P-value = 0.427,...... TDT P-value = 0.427, X<sup>2</sup>=2.779 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| Pickard, B. S., 2006 | rs2000869 - rs7479743 - rs6589832 - rs7925270 | GRIK4 | P-value = 0.246 betw...... P-value = 0.246 between SCZ cases and controls; P-value = 0.483 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs2000869 - rs7479743 - rs6589832 | GRIK4 | P-value = 0.498 betw...... P-value = 0.498 between BPD cases and controls; P-value = 0.391 between all cases and controls More... | Positive | ||
| Pickard, B. S., 2006 | rs2000869 - rs7479743 | GRIK4 | P-value = 0.421 betw...... P-value = 0.421 between BPD cases and controls; P-value = 0.448 between all cases and controls More... | Negative | ||
| Mansour, H. A., 2006 | rs1982350 - rs2896635 - rs2278749 - rs969486 - rs2290035 | ARNTL | global tests, P-valu...... global tests, P-value = 0.61, X<sup>2</sup>=9.18, df=11 More... | For ARNTL, these ana...... For ARNTL, these analyses revealed over-transmission of haplotypes encompassing five SNPs rs1982350, rs2896635, rs2278749, rs969486 and rs2290035. However, global tests of haplotypes involving these SNPs revealed no significant association. More... | Positive | |
| Lundorf, M. D.,2005 | rs1978340 - rs872123 - rs3749034 | GAD1 | Haplotypic associati...... Haplotypic association:in the Danish sample set, P-value = 0.016 for BPAD More... | Significant associat...... Significant association was found in the Danish sample set. More... | Positive | |
| Lundorf, M. D.,2005 | rs1978340 - rs872123 | GAD1 | Haplotypic associati...... Haplotypic association:in the Danish sample set, P-value = 0.012 for BPAD. More... | Significant associat...... Significant association was found in the Danish sample set. More... | Positive | |
| Pickard, B. S., 2006 | rs1954787 - rs4935752 - rs6589846 - rs4430518 | GRIK4 | P-value = 0.562 betw...... P-value = 0.562 between SCZ cases and controls; P-value = 0.32 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs1954787 - rs4935752 - rs6589846 | GRIK4 | P-value = 0.927 betw...... P-value = 0.927 between BPD cases and controls; P-value = 0.287 between all cases and controls More... | Negative | ||
| Pickard, B. S., 2006 | rs1954787 - rs4935752 | GRIK4 | P-value = 0.665 betw...... P-value = 0.665 between BPD cases and controls; P-value = 0.088 between all cases and controls More... | Negative | ||
| Thomson, P. A.,2005(a) | rs1954175 - rs1538977 - rs2492367 - rs2812393 | A-C-C-G A-C-C-G | TSNAX DISC1 | Global association t...... Global association test:for BP, P-value > 0.05(all) More... | No significant asso...... No significant association was found . More... | Negative |
| Thomson, P. A.,2005(a) | rs1954175 - rs1538977 - rs2492367 - rs2812393 | G-T-T-G G-T-T-G | TSNAX DISC1 | Global association t...... Global association test:for BP, P-value = 0.34(all), 0.29(male), 0.15(female); More... | No significant asso...... No significant association was found . More... | Negative |
| Thomson, P. A.,2005(a) | rs1954175 - rs1538977 - rs2492367 | TSNAX DISC1 | Global association t...... Global association test:for BP, P-value = 0.79(all), 0.3(male), 0.88(female); More... | No significant asso...... No significant association was found . More... | Negative | |
| Shi, J., 2007 | rs1948 - rs7178270 - rs1316971 - rs11633223 | G-C-G-G G-C-G-G | CHRNB4 | Uncorrected P-value ...... Uncorrected P-value = 0.017, Gene-wide Permutation P-value = 0.382 More... | The haplotype showed...... The haplotype showed nominally significant association with BD by Haploview analyses but the significance did not remain after permutation testing More... | Positive |
| Moskvina, V.,2011 | rs1938526 - rs8177272 | ANK3, TF | Corresponding intera...... Corresponding interaction p-values in the GAIN data is 0.464671 More... | No significant asso...... No significant association was found in interaction analysis. More... | Negative | |
| Moskvina, V.,2011 | rs1938526 - rs7638018 | ANK3, TF | Corresponding intera...... Corresponding interaction p-values in the GAIN data is 0.450873 More... | No significant asso...... No significant association was found in interaction analysis. More... | Negative | |
| Moskvina, V.,2011 | rs1938526 - rs7176022 | ANK3, LMAN1L | Corresponding intera...... Corresponding interaction p-values in the GAIN data is 0.427982 More... | No significant asso...... No significant association was found in interaction analysis. More... | Negative | |
| Moskvina, V.,2011 | rs1938526 - rs6495126 | ANK3 | Corresponding intera...... Corresponding interaction p-values in the GAIN data is 0.280345 More... | No significant asso...... No significant association was found in interaction analysis. More... | Negative | |
| Moskvina, V.,2011 | rs1938526 - rs4854762 | ANK3 | Corresponding intera...... Corresponding interaction p-values in the GAIN data is 0.354231 More... | No significant asso...... No significant association was found in interaction analysis. More... | Negative | |
| Moskvina, V.,2011 | rs1938526 - rs2472300 | ANK3 | Corresponding intera...... Corresponding interaction p-values in the GAIN data is 0.296906 More... | No significant asso...... No significant association was found in interaction analysis. More... | Negative | |
| Moskvina, V.,2011 | rs1938526 - rs2472299 | ANK3 | Corresponding intera...... Corresponding interaction p-values in the GAIN data is 0.319215 More... | No significant asso...... No significant association was found in interaction analysis. More... | Negative | |
| Moskvina, V.,2011 | rs1938526 - rs12638324 | ANK3 | Corresponding intera...... Corresponding interaction p-values in the GAIN data is 0.230296 More... | No significant asso...... No significant association was found in interaction analysis. More... | Negative | |
| Muller, D. J.,2011 | rs1935062 - rs947267 - rs778294 | C-T-C C-T-C | DAOA | FBAT:for total sampl...... FBAT:for total sample, variance of the S-statistic=51.9, Z-score=-2.57, P-value = 0.01, global P-value = 0.03; for European sample, variance of the S-statistic=48.4, Z-score=-2.97, P-value = 0.003, global P-value = 0.02 More... | Significant associat...... Significant association was found in both individual P-value and global P-value in BD. More... | Positive |
| Gaysina, D.,2010 | rs1935062 - rs947267 - rs778292 | DAOA | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=3.21, P-value = 0.67 for UK sample; X<sup>2</sup>=3.88, P-value = 0.57 for Canadian sample. More... | No significant asso...... No significant association was found . More... | Negative | |
| Muller, D. J.,2011 | rs1935062 - rs947267 | C-T C-T | DAOA | FBAT:for total sampl...... FBAT:for total sample, variance of the S-statistic=51.8, Z-score=-2.56, P-value = 0.01, global P-value = 0.06; for European sample, variance of the S-statistic=48.3, Z-score=-2.93, P-value = 0.003, global P-value = 0.02 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Gaysina, D.,2010 | rs1935062 - rs3741775 | DAOA DAO | Interaction analysis...... Interaction analysis:P-value = 0.027(>0.05 after correction) in the UK sample. More... | No significant asso...... No significant association was found . More... | Negative | |
| Chen, Y. S.,2004 | rs1935058 - rs2391191 - rs1935062 - rs947267 - rs954581 | T-G-A-C-T T-G-A-C-T | DAOA | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.004, OR=1.31, chi square=1.77, P-value > 0.05 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Chen, Y. S.,2004 | rs1935058 - rs2391191 - rs1935062 - rs947267 - rs954581 | C-A-C-A-T C-A-C-A-T | DAOA | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.004, OR=0.74, chi square=2.59, P-value > 0.05 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Chen, Y. S.,2004 | rs1935058 - rs2391191 - rs1935062 - rs947267 - rs954581 | T-G-A-A-C T-G-A-A-C | DAOA | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.004, OR=0.93, chi square=0.04, P-value > 0.05 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Chen, Y. S.,2004 | rs1935058 - rs2391191 - rs1935062 - rs947267 - rs954581 | T-G-C-A-T T-G-C-A-T | DAOA | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.004, OR=0.37, chi square=4.39, P-value = 0.0362 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Chen, Y. S.,2004 | rs1935058 - rs2391191 - rs1935062 - rs947267 - rs954581 | C-G-C-A-T C-G-C-A-T | DAOA | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.004, OR=0.08, chi square=7.56, P-value = 0.006 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Chen, Y. S.,2004 | rs1935058 - rs2391191 - rs1935062 - rs947267 - rs954581 | T-A-A-C-T T-A-A-C-T | DAOA | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.004, OR=0, chi square=8.1, P-value = 0.0044 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Chen, Y. S.,2004 | rs1935058 - rs2391191 - rs1935062 - rs947267 - rs954581 | C-A-A-A-C C-A-A-A-C | DAOA | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.004, OR=2.23, chi square=3.19, P-value = 0.0743 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Chen, Y. S.,2004 | rs1935058 - rs2391191 - rs1935062 - rs947267 - rs954581 | C-G-A-C-T C-G-A-C-T | DAOA | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.004, OR=2.99, chi square=6.13, P-value = 0.0133 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Chen, Y. S.,2004 | rs1935058 - rs2391191 - rs1935062 - rs947267 - rs954581 | T-G-A-A-T T-G-A-A-T | DAOA | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.004, OR=1.31, chi square=0.09, P-value > 0.05 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Gawlik, M.,2010 | rs1935058 - rs1935062 - rs2391191 - rs3916966 | DAOA | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.18 More... | No significant asso...... No significant association was found . More... | Negative | |
| Hattori, E.,2003 | rs1935058 - rs1341402 - rs2391191 - rs1935062 - rs947267 - rs778294 - rs954581 | C-C-G-A-C-A-T C-C-G-A-C-A-T | DAOA | TDT by Haplotype:glo...... TDT by Haplotype:global P-value = 0.0004(CNG), global P-value = 0.008(NIMH), For CNG pedigrees, P-value = 0.008, Transmission Ratio=0.18, For NIMH pedigrees, P-value = 0.3, Transmission Ratio=0.44 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Hattori, E.,2003 | rs1935058 - rs1341402 - rs2391191 - rs1935062 - rs947267 - rs778294 - rs954581 | C-T-A-A-A-G-C C-T-A-A-A-G-C | DAOA | TDT by Haplotype:glo...... TDT by Haplotype:global P-value = 0.0004(CNG), global P-value = 0.008(NIMH), For NIMH pedigrees, P-value = 0.8, Transmission Ratio=0.43 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Hattori, E.,2003 | rs1935058 - rs1341402 - rs2391191 - rs1935062 - rs947267 - rs778294 - rs954581 | C-T-A-C-A-G-T C-T-A-C-A-G-T | DAOA | TDT by Haplotype:glo...... TDT by Haplotype:global P-value = 0.0004(CNG), global P-value = 0.008(NIMH), For CNG pedigrees, P-value = 0.0003, Transmission Ratio=0.94, For NIMH pedigrees, P-value = 0.06, Transmission Ratio=0.6 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Hattori, E.,2003 | rs1935058 - rs1341402 - rs2391191 - rs1935062 - rs947267 - rs778294 - rs954581 | C-T-G-A-C-G-T C-T-G-A-C-G-T | DAOA | TDT by Haplotype:glo...... TDT by Haplotype:global P-value = 0.0004(CNG), global P-value = 0.008(NIMH), For CNG pedigrees, P-value = 0.1, Transmission Ratio=0.83 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Hattori, E.,2003 | rs1935058 - rs1341402 - rs2391191 - rs1935062 - rs947267 - rs778294 - rs954581 | T-T-G-A-A-G-C T-T-G-A-A-G-C | DAOA | TDT by Haplotype:glo...... TDT by Haplotype:global P-value = 0.0004(CNG), global P-value = 0.008(NIMH), For CNG pedigrees, P-value = 0.7, Transmission Ratio=0.4, For NIMH pedigrees, P-value = 0.06, Transmission Ratio=0.32 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Hattori, E.,2003 | rs1935058 - rs1341402 - rs2391191 - rs1935062 - rs947267 - rs778294 - rs954581 | T-T-G-A-A-G-T T-T-G-A-A-G-T | DAOA | TDT by Haplotype:glo...... TDT by Haplotype:global P-value = 0.0004(CNG), global P-value = 0.008(NIMH), For CNG pedigrees, P-value = 0.1, Transmission Ratio=0.17 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Hattori, E.,2003 | rs1935058 - rs1341402 - rs2391191 - rs1935062 - rs947267 - rs778294 - rs954581 | T-T-G-A-C-A-T T-T-G-A-C-A-T | DAOA | TDT by Haplotype:glo...... TDT by Haplotype:global P-value = 0.0004(CNG), global P-value = 0.008(NIMH), For NIMH pedigrees, P-value = 0.04, Transmission Ratio=0.29 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Hattori, E.,2003 | rs1935058 - rs1341402 - rs2391191 - rs1935062 - rs947267 - rs778294 - rs954581 | T-T-G-A-C-G-T T-T-G-A-C-G-T | DAOA | TDT by Haplotype:glo...... TDT by Haplotype:global P-value = 0.0004(CNG), global P-value = 0.008(NIMH), , For NIMH pedigrees, P-value = 0.1, Transmission Ratio=0.62 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Lohoff, F. W., 2008 (a) | rs1893154 - rs2846811 - rs8192595 | 1-1-1 (1=major alle...... 1-1-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1, X<sup>2&...... OR=1, X<sup>2</sup>=0.98, P-value =0.321 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs1893154 - rs2846811 - rs8192595 | 1-2-1 (1=major alle...... 1-2-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1.82, X<sup>...... OR=1.82, X<sup>2</sup>=2.06, P-value =0.151 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Lohoff, F. W., 2008 (a) | rs1893154 - rs2846811 - rs8192595 | 2-1-1 (1=major alle...... 2-1-1 (1=major allele, 2=minor allele) More... | ADCYAP1 | OR=1.08, X<sup>...... OR=1.08, X<sup>2</sup>=0.02, P-value =0.884 More... | Haplotype analysis d...... Haplotype analysis did not show any significant association with disease. More... | Negative |
| Li, J.,2011(a) | rs1883901 - rs10807187 - rs9462343 | A-G-G A-G-G | MDGA1 | Haplotype analysis:f...... Haplotype analysis:for BP, global P-value = 0.0391, individual P-value = 0.0167 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Li, J.,2011(a) | rs1883901 - rs10807187 - rs9462343 | G-G-A G-G-A | MDGA1 | Haplotype analysis:f...... Haplotype analysis:for BP, global P-value = 0.0391, individual P-value = 0.8409 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Li, J.,2011(a) | rs1883901 - rs10807187 - rs9462343 | G-G-G G-G-G | MDGA1 | Haplotype analysis:f...... Haplotype analysis:for BP, global P-value = 0.0391, individual P-value = 0.629 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Li, J.,2011(a) | rs1883901 - rs10807187 - rs9462343 | G-T-G G-T-G | MDGA1 | Haplotype analysis:f...... Haplotype analysis:for BP, global P-value = 0.0391, individual P-value = 0.2802 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Palo, O. M.,2010 | rs1860487 - rs648619 | A-A A-A | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=-1.098, FBAT P-value = 0.272 More... | No significant asso...... No significant association was found . More... | Negative |
| Roche, S.,2009 | rs1843809 - rs1386493 - rs2171363 - rs1386491 - rs6582078 - rs10506645 - rs1007023 | G-T-T-C-G-C-G G-T-T-C-G-C-G | TPH2 | haplotype:X<sup&g...... haplotype:X<sup>2</sup>=0.329, Individual P-value =0.5663 More... | No significant asso...... No significant association was found . More... | Negative |
| Roche, S.,2009 | rs1843809 - rs1386493 - rs2171363 - rs1386491 - rs6582078 - rs10506645 - rs1007023 | T-C-C-C-T-C-T T-C-C-C-T-C-T | TPH2 | haplotype:X<sup&g...... haplotype:X<sup>2</sup>=1.95, Individual P-value =0.1626 More... | No significant asso...... No significant association was found . More... | Negative |
| Roche, S.,2009 | rs1843809 - rs1386493 - rs2171363 - rs1386491 - rs6582078 - rs10506645 - rs1007023 | T-C-T-G-G-T-T T-C-T-G-G-T-T | TPH2 | haplotype:X<sup&g...... haplotype:X<sup>2</sup>=1.393, Individual P-value =0.2379 More... | No significant asso...... No significant association was found . More... | Negative |
| Roche, S.,2009 | rs1843809 - rs1386493 - rs2171363 - rs1386491 - rs6582078 - rs10506645 - rs1007023 | T-T-T-C-G-C-T T-T-T-C-G-C-T | TPH2 | haplotype:X<sup&g...... haplotype:X<sup>2</sup>=0.667, Individual P-value =0.4142 More... | No significant asso...... No significant association was found . More... | Negative |
| Hashimoto, R.,2005(a) | rs1811017 - rs140504 - rs131690 - rs131702 | A-A-A-T A-A-A-T | BCR | Haplotypic associati...... Haplotypic association: for BPII, global permutation P-value = 0.00041, 100, 000 simulations; permutation individual P-value = 0.0066 More... | Significant associat...... Significant association was found in both global P-value and individual P-value. More... | Positive |
| Hashimoto, R.,2005(a) | rs1811017 - rs140504 - rs131690 - rs131702 | A-G-G-G A-G-G-G | BCR | Haplotypic associati...... Haplotypic association: for BPII, global permutation P-value = 0.00041, 100, 000 simulations; permutation individual P-value = 0.0002 More... | Significant associat...... Significant association was found in both global P-value and individual P-value. More... | Positive |
| Zhao, Q.,2011 | rs1805502 - rs1805247 | A-A A-A | GRIN2B | Haplotypic associati...... Haplotypic association:X<sup>2</sup>=6.286, P-value = 0.012 More... | Significant associat...... Significant association was found in BPD. More... | Positive |
| Zhao, Q.,2011 | rs1805502 - rs1805247 | A-G A-G | GRIN2B | Haplotypic associati...... Haplotypic association:X<sup>2</sup>=38.25, P-value = 6.22E-10 More... | Significant associat...... Significant association was found in BPD. More... | Positive |
| Zhao, Q.,2011 | rs1805502 - rs1805247 | G-G G-G | GRIN2B | Haplotypic associati...... Haplotypic association:X<sup>2</sup>=0.121, P-value = 0.728 More... | No significant asso...... No significant association was found . More... | Negative |
| Fukuo, Y.,2010 | rs1805054 - rs4912138 - rs3790757 - rs9659997 | HTR6 | Haplotype-wise analy...... Haplotype-wise analysis:global P-value = 0.334 More... | No significant asso...... No significant association was found . More... | Negative | |
| Fukuo, Y.,2010 | rs1805054 - rs4912138 - rs3790757 | HTR6 | Haplotype-wise analy...... Haplotype-wise analysis:global P-value = 0.23 More... | No significant asso...... No significant association was found . More... | Negative | |
| Fukuo, Y.,2010 | rs1805054 - rs4912138 | HTR6 | Haplotype-wise analy...... Haplotype-wise analysis:global P-value = 0.189 More... | No significant asso...... No significant association was found . More... | Negative | |
| Yosifova, A.,2009 | rs1800883 - rs2581841 - rs10254608 | C-C-C C-C-C | HTR5A | Haplotypic associati...... Haplotypic association:P-value = 0.00041, Odds ratio (95% CI)=0.6 (0.43-0.78) More... | Significant associat...... Significant association was found. More... | Positive |
| Yosifova, A.,2009 | rs1800883 - rs2581841 - rs10254608 | G-T-A G-T-A | HTR5A | Haplotypic associati...... Haplotypic association:P-value = 0.00045, Odds ratio (95% CI)=1.6 (1.22-1.99) More... | Significant associat...... Significant association was found. More... | Positive |
| Bloch, P. J., 2010 | rs1787984 - rs585247 - rs3974759 | ATT ATT | IMPA2 | Chi square=2.567, P-...... Chi square=2.567, P-value = 0.1091, permutation P-value = 0.6965 More... | Haplotype analysis d...... Haplotype analysis did not show any statistically significant associations. More... | Negative |
| Bloch, P. J., 2010 | rs1787984 - rs585247 - rs3974759 | GCA GCA | IMPA2 | Chi square=3.772, P-...... Chi square=3.772, P-value = 0.0521, permutation P-value = 0.3893 More... | Haplotype analysis d...... Haplotype analysis did not show any statistically significant associations. More... | Negative |
| Bloch, P. J., 2010 | rs1787984 - rs585247 - rs3974759 | HTA HTA | IMPA2 | Chi square=1.61, P-v...... Chi square=1.61, P-value = 0.2044, permutation P-value = 0.9069 More... | Haplotype analysis d...... Haplotype analysis did not show any statistically significant associations. More... | Negative |
| Bloch, P. J., 2010 | rs1787984 - rs585247 - rs3974759 | ATA ATA | IMPA2 | Chi square=1.68, P-v...... Chi square=1.68, P-value = 0.195, permutation P-value = 0.8942 More... | Haplotype analysis d...... Haplotype analysis did not show any statistically significant associations. More... | Negative |
| Bloch, P. J., 2010 | rs1787984 - rs585247 - rs3974759 | GTT GTT | IMPA2 | Chi square=1.479, P-...... Chi square=1.479, P-value = 0.2239, permutation P-value = 0.9358 More... | Haplotype analysis d...... Haplotype analysis did not show any statistically significant associations. More... | Negative |
| McNabb, L. D.,2005 | rs1786581 - rs1249624 | CHMP1B | Haplotypic associati...... Haplotypic association:X<sup>2</sup>=7.16, df=3, P-value = 0.07 More... | No significant asso...... No significant association was found . More... | Negative | |
| Roche, S., 2007 | rs1785454 - rs933151 | TRPM2 | TDT P-value = 0.478,...... TDT P-value = 0.478, X<sup>2</sup>=1.476 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| Kishi, T.,2009(c) | rs17721321 - rs6085086 - rs3746684 - rs3746682 - rs4815787 | PROKR2 | likelihood ratio tes...... likelihood ratio test:in total samples:Global P-value = 0.00204 in BP, in male:Global P-value = 0.242 in BP, in female:Global P-value = 0.00175, Corrected P-value = 0.00350 in BP. More... | We detected signific...... We detected significant associations in BP. More... | Positive | |
| Palo, O. M.,2010 | rs176481 - rs887882 | G-A G-A | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=-1.659, FBAT P-value = 0.097 More... | No significant asso...... No significant association was found . More... | Negative |
| Otani, K.,2005(b) | rs175170 - rs175174 | ZDHHC8 | Haplotypic associati...... Haplotypic association:for BPD, P-value = 0.296 More... | No significant asso...... No significant association was found . More... | Negative | |
| Gaysina, D.,2009 | rs17470454 - rs16876571 - rs2619539 | DTNBP1 | Three Marker Haploty...... Three Marker Haplotype Sliding-Window Analysis:Global P-value = 0.1, Individual P-value = 0.04 More... | No statistically sig...... No statistically significant association was found. More... | Negative | |
| Kahler, A. K., 2010 | rs17452121 - rs2186122 | AT AT | PDE4B | Individual P-value =...... Individual P-value = 0.010, global P-value = 0.030 More... | the best 2-SNP resul...... the best 2-SNP result More... | Positive |
| Pickard, B. S.,2009 | rs173383 - rs243310 - rs1886782 | G-T-A G-T-A | NPAS3 | Individual P-value =...... Individual P-value = 0.0027, OR= 1.6809 (95% CI:1.2699-2.2249) More... | Significant associat...... Significant association with BPD was found. More... | Positive |
| McQuillin, A.,2009 | rs1718119 - rs2230912 | P2RX7 | Haplotypic associati...... Haplotypic association:Global LRT=9.52, df=3, Global empirical P-value = 0.019 More... | Significant associat...... Significant association with BPD was found. More... | Positive | |
| Scholz, C. J.,2010 | rs1705236 - rs1798086 - rs17226863 - rs4500567 - rs1397552 | A-A-G-C-G A-A-G-C-G | TSPAN8 | Association of Haplo...... Association of Haplotypes:Nominal P-value = 0.15, Permutation P-value = 0.927 More... | No significant asso...... No significant association was found . More... | Negative |
| Scholz, C. J.,2010 | rs1705236 - rs1798086 - rs17226863 - rs4500567 - rs1397552 | A-G-C-C-G A-G-C-C-G | TSPAN8 | Association of Haplo...... Association of Haplotypes:Nominal P-value = 0.519, Permutation P-value = 1 More... | No significant asso...... No significant association was found . More... | Negative |
| Scholz, C. J.,2010 | rs1705236 - rs1798086 - rs17226863 - rs4500567 - rs1397552 | A-G-G-C-G A-G-G-C-G | TSPAN8 | Association of Haplo...... Association of Haplotypes:Nominal P-value = 0.482, Permutation P-value = 1 More... | No significant asso...... No significant association was found . More... | Negative |
| Scholz, C. J.,2010 | rs1705236 - rs1798086 - rs17226863 - rs4500567 - rs1397552 | A-G-G-G-G A-G-G-G-G | TSPAN8 | Association of Haplo...... Association of Haplotypes:Nominal P-value = 0.001, Permutation P-value = 0.012 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Scholz, C. J.,2010 | rs1705236 - rs1798086 - rs17226863 - rs4500567 - rs1397552 | T-G-G-C-A T-G-G-C-A | TSPAN8 | Association of Haplo...... Association of Haplotypes:Nominal P-value = 0.587, Permutation P-value = 1 More... | No significant asso...... No significant association was found . More... | Negative |
| Papiol, S.,2004 | rs16944 - (IL1RN_intron 2_VNTR) | C-VNTR(A2) C-VNTR(A2) | IL1B IL1RN | Haplotype analysis:B...... Haplotype analysis:Bipolar disorder v controls:chi square= 9.81, global P-value = 0.043; chi square= 8.09, individual P-value = 0.004; OR = 2.26(95% CI: 1.22 to 4.17).Bipolar disorder FH+ v controls:chi square= 15.90, global P-value = 0.0031; chi square= 15.41, individual P-value = 0.00009; OR= 3.18 (95% CI: 1.66 to 6.05). More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Ivanova, M. A.,2012 | rs16917237 - rs12273363 | G-T G-T | BDNF | Association results:...... Association results:genotype frequency,0.68%/0.57%(case/control); P=0.001,narrow; 0.66%/0.59(case/control)%; P=0.023, broad More... | The haplotype was mo...... The haplotype was more frequently found in the group of patients compared with controls. More... | Positive |
| Ivanova, M. A.,2012 | rs16917237 - rs12273363 | T-T T-T | BDNF | Association results:...... Association results:genotype frequency,0.21%/0.29%(case/control); P=0.008, narrow; 0.22%/0.28%(case/control); P=0.043, broad More... | The haplotype was ra...... The haplotype was rarer in the group of patients compared with controls. More... | Positive |
| Gaysina, D.,2009 | rs16876571 - rs2619539 - rs3213207 - rs760761 | DTNBP1 | Four Marker Haplotyp...... Four Marker Haplotype Sliding-Window Analysis:Global P-value = 0.02 More... | The four-marker hapl...... The four-marker haplotype G-C-G-T (rs16876571- rs2619539-rs3213207-rs760761) was also overrepresented among patients with BD compared to controls (P-value = 0.02). More... | Positive | |
| Gaysina, D.,2009 | rs16876571 - rs2619539 - rs3213207 | DTNBP1 | Three Marker Haploty...... Three Marker Haplotype Sliding-Window Analysis:Global =0.027, Individual P-value = 0.015. More... | It showed a signific...... It showed a significant difference with a significant overrepresentation of the G-C-G haplotype in bipolar disorder More... | Positive | |
| Palo, O. M., 2007 | rs1655285 - rs751229 - rs3738401 | G-T-A G-T-A | TSNAX DISC1 | Individual P-value =...... Individual P-value = 0.261 in all, P-value = 0.039 in males, P-value = 0.965 in females; global P-value = 0.42 in all, P-value = 0.183 in males, P-value = 0.426 in females, with bipolar spectrum disorder More... | Positive | |
| Palo, O. M., 2007 | rs1655285 - rs751229 | G-T G-T | TSNAX DISC1 | Individual P-value =...... Individual P-value = 0.399 in all, P-value = 0.704 in males, P-value = 0.418 in females; global P-value = 0.188 in all, P-value = 0.427 in males, P-value = 0.047 in females, with bipolar spectrum disorder More... | Positive | |
| Barden, N., 2006 | rs1653625 - rs4980999 - rs3817190 - rs28360477 | C-C-T-C C-C-T-C | P2RX4 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.012, LRS (global P-value)=0.039 More... | We identified global...... We identified global significant P-values for blocks 4 with P-value = 0.0390. The haplotype block 4 encloses the associated SNP P2RX4-UTR3A, hence supporting the prior single marker analysis. More... | Positive |
| Barden, N., 2006 | rs1653625 - rs4980999 - rs3817190 - rs28360477 | C-C-A-C C-C-A-C | P2RX4 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.314, LRS (global P-value)=0.039 More... | We identified global...... We identified global significant P-values for blocks 4 with P-value = 0.0390. The haplotype block 4 encloses the associated SNP P2RX4-UTR3A, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs4980999 - rs3817190 - rs28360477 | G-C-T-C G-C-T-C | P2RX4 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.065, LRS (global P-value)=0.039 More... | We identified global...... We identified global significant P-values for blocks 4 with P-value = 0.0390. The haplotype block 4 encloses the associated SNP P2RX4-UTR3A, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs4980999 - rs3817190 - rs28360477 | C-T-T-C C-T-T-C | P2RX4 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.179, LRS (global P-value)=0.039 More... | We identified global...... We identified global significant P-values for blocks 4 with P-value = 0.0390. The haplotype block 4 encloses the associated SNP P2RX4-UTR3A, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs4980999 - rs3817190 - rs28360477 | G-C-A-T G-C-A-T | P2RX4 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.235, LRS (global P-value)=0.039 More... | We identified global...... We identified global significant P-values for blocks 4 with P-value = 0.0390. The haplotype block 4 encloses the associated SNP P2RX4-UTR3A, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs4980999 - rs3817190 - rs28360477 | G-C-A-C G-C-A-C | P2RX4 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.411, LRS (global P-value)=0.039 More... | We identified global...... We identified global significant P-values for blocks 4 with P-value = 0.0390. The haplotype block 4 encloses the associated SNP P2RX4-UTR3A, hence supporting the prior single marker analysis. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190 | A-A-G-G-C-T-T A-A-G-G-C-T-T | P2RX7 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.362, LRS (global P-value)=0.0249 with a sliding window strategy More... | The other 7-SNP posi...... The other 7-SNP positively associated window bordered by markers P2RX7-UTR3A and CAMKK2-E01B comprises blocks 3 and 4 and the associated marker P2RX4-UTR3A. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190 | A-C-A-A-C-C-A A-C-A-A-C-C-A | P2RX7 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.685, LRS (global P-value)=0.0249 with a sliding window strategy More... | The other 7-SNP posi...... The other 7-SNP positively associated window bordered by markers P2RX7-UTR3A and CAMKK2-E01B comprises blocks 3 and 4 and the associated marker P2RX4-UTR3A. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190 | A-C-A-A-C-C-T A-C-A-A-C-C-T | P2RX7 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.487, LRS (global P-value)=0.0249 with a sliding window strategy More... | The other 7-SNP posi...... The other 7-SNP positively associated window bordered by markers P2RX7-UTR3A and CAMKK2-E01B comprises blocks 3 and 4 and the associated marker P2RX4-UTR3A. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190 | A-C-A-A-C-T-T A-C-A-A-C-T-T | P2RX7 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.544, LRS (global P-value)=0.0249 with a sliding window strategy More... | The other 7-SNP posi...... The other 7-SNP positively associated window bordered by markers P2RX7-UTR3A and CAMKK2-E01B comprises blocks 3 and 4 and the associated marker P2RX4-UTR3A. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190 | A-C-A-A-G-C-A A-C-A-A-G-C-A | P2RX7 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.106, LRS (global P-value)=0.0249 with a sliding window strategy More... | The other 7-SNP posi...... The other 7-SNP positively associated window bordered by markers P2RX7-UTR3A and CAMKK2-E01B comprises blocks 3 and 4 and the associated marker P2RX4-UTR3A. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190 | A-C-A-A-G-C-T A-C-A-A-G-C-T | P2RX7 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.073, LRS (global P-value)=0.0249 with a sliding window strategy More... | The other 7-SNP posi...... The other 7-SNP positively associated window bordered by markers P2RX7-UTR3A and CAMKK2-E01B comprises blocks 3 and 4 and the associated marker P2RX4-UTR3A. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190 | A-C-G-A-C-C-A A-C-G-A-C-C-A | P2RX7 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.163, LRS (global P-value)=0.0249 with a sliding window strategy More... | The other 7-SNP posi...... The other 7-SNP positively associated window bordered by markers P2RX7-UTR3A and CAMKK2-E01B comprises blocks 3 and 4 and the associated marker P2RX4-UTR3A. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190 | A-C-G-A-C-C-T A-C-G-A-C-C-T | P2RX7 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.327, LRS (global P-value)=0.0249 with a sliding window strategy More... | The other 7-SNP posi...... The other 7-SNP positively associated window bordered by markers P2RX7-UTR3A and CAMKK2-E01B comprises blocks 3 and 4 and the associated marker P2RX4-UTR3A. More... | Negative |
| Barden, N., 2006 | rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190 | C-C-A-A-C-C-T C-C-A-A-C-C-T | P2RX7 CAMKK2 | chi-square P-value =...... chi-square P-value = 0.012, LRS (global P-value)=0.0249 with a sliding window strategy More... | The other 7-SNP posi...... The other 7-SNP positively associated window bordered by markers P2RX7-UTR3A and CAMKK2-E01B comprises blocks 3 and 4 and the associated marker P2RX4-UTR3A. More... | Positive |
| Okuda, A.,2010 | rs1630250 - rs766288 - rs6662926 | C-C-G C-C-G | TSNAX | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.724, individual P-value = 0.712 More... | No significant asso...... No significant association was found . More... | Negative |
| Okuda, A.,2010 | rs1630250 - rs766288 - rs6662926 | C-T-G C-T-G | TSNAX | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.724, individual P-value = 0.421 More... | No significant asso...... No significant association was found . More... | Negative |
| Okuda, A.,2010 | rs1630250 - rs766288 - rs6662926 | G-C-C G-C-C | TSNAX | Haplotype analysis:g...... Haplotype analysis:global P-value = 0.724, individual P-value = 0.677 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M., 2007 | rs1630250 - rs1615409 - rs1655285 | G-C-G G-C-G | TSNAX | Individual P-value =...... Individual P-value = 0.065 in all, P-value = 0.153 in males, P-value = 0.286 in females; global P-value = 0.089 in all, P-value = 0.11 in males, P-value = 0.378 in females, with bipolar spectrum disorder More... | Negative | |
| Palo, O. M., 2007 | rs1630250 - rs1615409 | G-C G-C | TSNAX | Individual P-value =...... Individual P-value = 0.007 in all, P-value = 0.052 in males, P-value = 0.098 in females; global P-value = 0.007 in all, P-value = 0.052 in males, P-value = 0.097 in females, with bipolar spectrum disorder More... | a major haplotype co...... a major haplotype containing rs1630250 and rs1615409 within the TSNAX gene was over-transmitted to affected females and males More... | Positive |
| Palo, O. M., 2007 | rs1615409 - rs1655285 - rs751229 | C-G-T C-G-T | TSNAX DISC1 | Individual P-value =...... Individual P-value = 0.085 in all, P-value = 0.234 in males, P-value = 0.204 in females; global P-value = 0.114 in all, P-value = 0.287 in males, P-value = 0.106 in females, with bipolar spectrum disorder More... | Negative | |
| Palo, O. M., 2007 | rs1615409 - rs1655285 | C-G C-G | TSNAX | Individual P-value =...... Individual P-value = 0.078 in all, P-value = 0.201 in males, P-value = 0.248 in females; global P-value = 0.102 in all, P-value = 0.162 in males, P-value = 0.361 in females, with bipolar spectrum disorder More... | Negative | |
| Severinsen, J. E., 2006 (a) | rs1573745 - rs710193 - rs133073 - rs133070 - rs133069 | ST13 MCHR1 | Empirical overall P-...... Empirical overall P-value = 0.2604 in BPD and SZ, Empirical overall P-value = 0.1587 in BPD More... | Negative | ||
| Severinsen, J. E., 2006 (a) | rs1573745 - rs710193 - rs133073 - rs133070 | ST13 MCHR1 | Empirical overall P-...... Empirical overall P-value = 0.1346 in BPD and SZ, Empirical overall P-value = 0.3998 in BPD More... | Negative | ||
| Severinsen, J. E., 2006 (a) | rs1573745 - rs710193 - rs133073 | ST13 MCHR1 | Empirical overall P-...... Empirical overall P-value = 0.0632 in BPD and SZ, Empirical overall P-value = 0.123 in BPD More... | Negative | ||
| Severinsen, J. E., 2006 (a) | rs1573745 - rs710193 | ST13 | Empirical overall P-...... Empirical overall P-value = 0.4429 in BPD and SZ, Empirical overall P-value = 0.5903 in BPD More... | Negative | ||
| Xiao, Y.,2011 | rs1572899 - rs1954175 | A-C A-C | DISC1 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.987 More... | No significant asso...... No significant association was found . More... | Negative |
| Schosser, A.,2011 | rs1568565 - rs7629772 | APOD | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.941, global P-value = 0.587 More... | No significant asso...... No significant association was found . More... | Negative | |
| Roche, S., 2007 | rs1556314 - rs9974831 | TRPM2 | TDT P-value = 0.769,...... TDT P-value = 0.769, X<sup>2</sup>=1.134 More... | There was no evidenc...... There was no evidence for association in the multi-marker association analyses More... | Negative | |
| McQuillin, A., 2006 | rs1556314 - rs1785467 - D21S171 | TRPM2 | overall empirical si...... overall empirical significance P-value = 0.011 More... | Using the asymptotic...... Using the asymptotic distribution, the test for haplotype association for the two associated SNPs and the associated microsatellite D21S171 of P=0.007. The empirical P-values using permutation tests was 0.011. More... | Positive | |
| McQuillin, A., 2006 | rs1556314 - rs1785467 | TRPM2 | overall empirical si...... overall empirical significance P-value = 0.010 More... | Using the asymptotic...... Using the asymptotic distribution, the test for haplotype association for the two associated SNPs rs1556314 and rs1785467 was significant at P=0.009. The empirical P-values using permutation tests was P=0.01. More... | Positive | |
| Thomson, P. A.,2005(a) | rs1538977 - rs2492367 - rs2812393 - rs1322784 | T-T-G-T T-T-G-T | TSNAX DISC1 | Global association t...... Global association test:for BP, P-value = 0.0016(all), 0.75(male), 0.00026(female); More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Thomson, P. A.,2005(a) | rs1538977 - rs2492367 - rs2812393 | T-T-G T-T-G | TSNAX DISC1 | Global association t...... Global association test:for BP, P-value = 0.59(all), 0.93(male), 0.022(female); More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M., 2007 | rs1538977 - rs1322784 | A-A A-A | DISC1 | Individual P-value =...... Individual P-value = 0.622 in all, P-value = 0.952 in males, P-value = 0.363 in females; global P-value = 0.683 in all, P-value = 0.689 in males, P-value = 0.757 in females, with bipolar spectrum disorder More... | Negative | |
| Maeda, K., 2006 | rs1538975 - rs3738401 - DISC1_Exon2_Pro/Leu - rs1954175 - rs2273890 - rs1407598 - rs6675281 - rs1000731 - rs821653 - rs821616 - rs3524 - rs3737597 | G-G-C-A-T-A-C-G-T-A-...... G-G-C-A-T-A-C-G-T-A-C-G More... | DISC1 | P-value = 0.01, P-va...... P-value = 0.01, P-value = 0.004 for overtransmission of HP1 to affected females More... | The study obtained t...... The study obtained the significance only from the total 12 marker haplotype. HP1 was overtransmitted to the affected subjects. The overtransmission of HP1 was exclusively to the affected females. More... | Positive |
| Maeda, K., 2006 | rs1538975 - rs3738401 - DISC1_Exon2_Pro/Leu - rs1954175 - rs2273890 - rs1407598 - rs6675281 - rs1000731 - rs821653 - rs821616 - rs3524 - rs3737597 | G-G-C-A-T-C-C-A-T-A-...... G-G-C-A-T-C-C-A-T-A-C-G More... | DISC1 | data not shown data not shown | The study obtained t...... The study obtained the significance only from the total 12 marker haplotype. HP2 was undertransmitted to the affected subjects. More... | Positive |
| Magno, L. A.,2011 | rs1536057 - rs2802292 - rs3813498 - rs1935952 | A-G-C-G A-G-C-G | FOXO3 | Chi-square tests:X&l...... Chi-square tests:X<sup>2</sup>=3.44, P-value = 0.0636 More... | No significant asso...... No significant association was found . More... | Negative |
| Magno, L. A.,2011 | rs1536057 - rs2802292 - rs3813498 - rs1935952 | A-G-T-C A-G-T-C | FOXO3 | Chi-square tests:X&l...... Chi-square tests:X<sup>2</sup>=0.041, P-value = 0.8403 More... | No significant asso...... No significant association was found . More... | Negative |
| Magno, L. A.,2011 | rs1536057 - rs2802292 - rs3813498 - rs1935952 | A-G-T-G A-G-T-G | FOXO3 | Chi-square tests:X&l...... Chi-square tests:X<sup>2</sup>=5.886, P-value = 0.0153 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Magno, L. A.,2011 | rs1536057 - rs2802292 - rs3813498 - rs1935952 | G-G-C-G G-G-C-G | FOXO3 | Chi-square tests:X&l...... Chi-square tests:X<sup>2</sup>=0.307, P-value = 0.5796 More... | No significant asso...... No significant association was found . More... | Negative |
| Magno, L. A.,2011 | rs1536057 - rs2802292 - rs3813498 - rs1935952 | G-G-T-C G-G-T-C | FOXO3 | Chi-square tests:X&l...... Chi-square tests:X<sup>2</sup>=1.327, P-value = 0.2493 More... | No significant asso...... No significant association was found . More... | Negative |
| Magno, L. A.,2011 | rs1536057 - rs2802292 - rs3813498 - rs1935952 | G-G-T-G G-G-T-G | FOXO3 | Chi-square tests:X&l...... Chi-square tests:X<sup>2</sup>=1.064, P-value = 0.3023 More... | No significant asso...... No significant association was found . More... | Negative |
| Magno, L. A.,2011 | rs1536057 - rs2802292 - rs3813498 - rs1935952 | G-T-C-G G-T-C-G | FOXO3 | Chi-square tests:X&l...... Chi-square tests:X<sup>2</sup>=1.537, P-value = 0.2151 More... | No significant asso...... No significant association was found . More... | Negative |
| Magno, L. A.,2011 | rs1536057 - rs2802292 - rs3813498 - rs1935952 | G-T-T-C G-T-T-C | FOXO3 | Chi-square tests:X&l...... Chi-square tests:X<sup>2</sup>=2.416, P-value = 0.1201 More... | No significant asso...... No significant association was found . More... | Negative |
| Magno, L. A.,2011 | rs1536057 - rs2802292 - rs3813498 - rs1935952 | G-T-T-G G-T-T-G | FOXO3 | Chi-square tests:X&l...... Chi-square tests:X<sup>2</sup>=0.677, P-value = 0.4107 More... | No significant asso...... No significant association was found . More... | Negative |
| Thomson, P. A., 2007 | rs1503491 - rs553950 - rs327329 - rs7007662 | NRG1 | P-value = 0.0029 for...... P-value = 0.0029 for SZ and BP combined More... | Positive | ||
| Thomson, P. A., 2007 | rs1503491 - rs553950 - rs327329 | T-T-T T-T-T | NRG1 | P-value = 0.0017 for...... P-value = 0.0017 for SZ and BP combined More... | Positive | |
| Walker, R. M.,2010 | rs1503491 - rs553950 - rs327329 | NRG1 | Haplotypic associati...... Haplotypic association:P-value = 0.084 for Scottish 1, P-value = 0.57 for Scottish 2, P-value = 0.69 for merged Scottish More... | No significant asso...... No significant association was found . More... | Negative | |
| Thomson, P. A., 2007 | rs1503491 - rs553950 | NRG1 | P-value = 0.0117 for...... P-value = 0.0117 for SZ and BP combined More... | Positive | ||
| Walker, R. M.,2010 | rs1503491 - rs553950 | NRG1 | Haplotypic associati...... Haplotypic association:P-value = 0.037 for Scottish 1, P-value = 0.79 for Scottish 2, P-value = 0.14 for merged Scottish More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Van Den Bogaert, A., 2006 (a) | rs1487275 - rs4474484 | A-G, C-A, A-A A-G, C-A, A-A | TPH2 | global P-value = 0.4...... global P-value = 0.42 More... | For hapblock 3, no s...... For hapblock 3, no significant association was identified with BP disorder. More... | Negative |
| Roche, S.,2009 | rs1487275 - rs1386486 - rs1386482 | G-T-A G-T-A | TPH2 | haplotype:X<sup&g...... haplotype:X<sup>2</sup>=2.829, Individual P-value =0.0926 More... | No significant asso...... No significant association was found . More... | Negative |
| Roche, S.,2009 | rs1487275 - rs1386486 - rs1386482 | T-C-C T-C-C | TPH2 | haplotype:X<sup&g...... haplotype:X<sup>2</sup>=5.607, Individual P-value =0.0179 More... | Significant associat...... Significant association was found. More... | Positive |
| Roche, S.,2009 | rs1487275 - rs1386486 - rs1386482 | T-T-A T-T-A | TPH2 | haplotype:X<sup&g...... haplotype:X<sup>2</sup>=2.522, Individual P-value =0.1122 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M., 2007 | rs1411771 - rs980989 | T-G T-G | DISC1 | Individual P-value =...... Individual P-value = 0.269 in all, P-value = 0.85 in males, P-value = 0.185 in females; global P-value = 0.429 in all, P-value = 0.631 in males, P-value = 0.43 in females, with bipolar spectrum disorder More... | Negative | |
| Zandi, P. P., 2008 (b) | rs1411187 - rs6986303 | ADCY8 ST3GAL1 | Global X<sup>2...... Global X<sup>2</sup>=28.90; global P-value = 3.0E-04 More... | Multi-locus analyses...... Multi-locus analyses suggested joint effects between ADCY8 and ST3GAL1 , with at least one copy of the ''high risk'' allele required at both genes for association with BP More... | Positive | |
| Otani, K.,2005(a) | rs140681 - rs140683 | A-A A-A | GABRA5 | Haplotypic associati...... Haplotypic association:for BPD1, P-value > 0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Otani, K.,2005(a) | rs140681 - rs140683 | A-T A-T | GABRA5 | Haplotypic associati...... Haplotypic association:for BPD1, chi square= 6.69, P-value = 0.039 More... | Significant associat...... Significant association was found in BPD1. More... | Positive |
| Otani, K.,2005(a) | rs140681 - rs140683 | G-A G-A | GABRA5 | Haplotypic associati...... Haplotypic association:for BPD1, P-value > 0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Otani, K.,2005(a) | rs140681 - rs140683 | G-T G-T | GABRA5 | Haplotypic associati...... Haplotypic association:for BPD1, P-value > 0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1404195 - rs1570637 | A-A A-A | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=1.322, FBAT P-value = 0.186 More... | No significant asso...... No significant association was found . More... | Negative |
| Severinsen, J. E., 2006 (b) | rs138881 - rs138880 - rs2239848 - rs138855 | BRD1 | P-value = 0.0013 in ...... P-value = 0.0013 in BD, P-value = 0.0003 in BD and SZ More... | Highly significant o...... Highly significant overall P-values (as low as 0.00001) were observed in especially the 3- and 4-marker analysis involving the BRD1 SNPs rs138855, rs2239848, rs138880 and rs138881. More... | Positive | |
| Severinsen, J. E., 2006 (b) | rs138881 - rs138880 - rs2239848 | BRD1 | P-value = 0.2096 in ...... P-value = 0.2096 in BD, P-value = 0.155 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs138881 - rs138880 | BRD1 | P-value = 0.1822 in ...... P-value = 0.1822 in BD, P-value = 0.0681 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs138880 - rs2239848 - rs138855 - rs4468 | BRD1 | P-value = 0.1877 in ...... P-value = 0.1877 in BD, P-value = 0.0607 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs138880 - rs2239848 - rs138855 | BRD1 | P-value = 0.00006 in...... P-value = 0.00006 in BD, P-value = 0.00005 in BD and SZ More... | Highly significant o...... Highly significant overall P-values (as low as 0.00001) were observed in especially the 3- and 4-marker analysis involving the BRD1 SNPs rs138855, rs2239848, rs138880 and rs138881. More... | Positive | |
| Severinsen, J. E., 2006 (b) | rs138880 - rs2239848 | BRD1 | P-value = 0.0797 in ...... P-value = 0.0797 in BD, P-value = 0.0381 in BD and SZ More... | Positive | ||
| Nyegaard, M., 2010 | rs138864 - rs2239848 | GG GG | BRD1 | None of the 11 Seque...... None of the 11 Sequenom SNPs showed association with BPD. More... | Negative | |
| Severinsen, J. E., 2006 (b) | rs138855 - rs4468 - D22S1169 - D22S922 | BRD1 | P-value = 0.5341 in ...... P-value = 0.5341 in BD, P-value = 0.1149 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs138855 - rs4468 - D22S1169 | BRD1 | P-value = 0.5369 in ...... P-value = 0.5369 in BD, P-value = 0.1374 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs138855 - rs4468 | BRD1 | P-value = 0.0769 in ...... P-value = 0.0769 in BD, P-value = 0.3182 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs138855 - rs2239848 - rs138880 - rs138881 | G-G-C-A G-G-C-A | BRD1 | P-value = 8E-05 in B...... P-value = 8E-05 in BD, P-value = 2E-05 in BD and SZ More... | Positive | |
| Severinsen, J. E., 2006 (b) | rs138855 - rs2239848 - rs138880 | G-G-C G-G-C | BRD1 | P-value = 3E-06 in B...... P-value = 3E-06 in BD, P-value = 1E-06 in BD and SZ More... | A 3-marker core hapl...... A 3-marker core haplotype spanning BRD1 SNPs rs138855, rs2239848 and rs138880 had a frequency of around 9% in cases against only 1% in controls, producing a haplotype specific P-value of order 1E-06. More... | Positive |
| Severinsen, J. E., 2006 (b) | rs138855 - rs138880 - rs138881 | G-C-A G-C-A | BRD1 | P-value = 1E-04 in B...... P-value = 1E-04 in BD, P-value = 4E-05 in BD and SZ More... | Positive | |
| Severinsen, J. E., 2006 (b) | rs138855 - rs138880 - rs138881 | G-C-G G-C-G | BRD1 | P-value = 0.0018 in ...... P-value = 0.0018 in BD, P-value = 0.0022 in BD and SZ More... | Positive | |
| Severinsen, J. E., 2006 (b) | rs138855 - rs138880 | G-C G-C | BRD1 | P-value = 1.6E-06 in...... P-value = 1.6E-06 in BD, P-value = 2.8E-07 in BD and SZ More... | Removing the rare mi...... Removing the rare middle SNP rs2239848 from the analysis resulted in a reduced 2-marker 'risk' haplotype (G-C) showing a frequency of ~10% in cases versus ~1% in controls. More... | Positive |
| Nyegaard, M., 2010 | rs138841 - rs138855 - rs138864 | CGG CGG | BRD1 | None of the 11 Seque...... None of the 11 Sequenom SNPs showed association with BPD. More... | Negative | |
| Nyegaard, M., 2010 | rs138841 - rs138855 | CG CG | BRD1 | None of the 11 Seque...... None of the 11 Sequenom SNPs showed association with BPD. More... | Negative | |
| Nyegaard, M., 2010 | rs138820 - rs4468 - rs138841 | CCA CCA | BRD1 | None of the 11 Seque...... None of the 11 Sequenom SNPs showed association with BPD. More... | Negative | |
| Nyegaard, M., 2010 | rs138820 - rs4468 - rs138841 | TTC TTC | BRD1 | None of the 11 Seque...... None of the 11 Sequenom SNPs showed association with BPD. More... | Negative | |
| Nyegaard, M., 2010 | rs138820 - rs4468 | CC CC | BRD1 | None of the 11 Seque...... None of the 11 Sequenom SNPs showed association with BPD. More... | Negative | |
| Nyegaard, M., 2010 | rs138820 - rs4468 | TT TT | BRD1 | None of the 11 Seque...... None of the 11 Sequenom SNPs showed association with BPD. More... | Negative | |
| Grigoroiu-Serbanescu, M.,2008 | rs1386497 - rs11834097 - rs4760820 - rs17722134 | TPH2 | P value for the glob...... P value for the global X<sup>2</sup>=0.0096 More... | This haplotype was s...... This haplotype was significant in the total sample More... | Positive | |
| Grigoroiu-Serbanescu, M.,2008 | rs1386497 - rs11834097 - rs4760820 - rs17722134 | ACCA ACCA | TPH2 | OR=1.93 OR=1.93 | The ORs and frequenc...... The ORs and frequencies in cases and controls indicate that the haplotypes ACCA and ACCG are associated with the BPI disorder. More... | Positive |
| Grigoroiu-Serbanescu, M.,2008 | rs1386497 - rs11834097 - rs4760820 - rs17722134 | ACCG ACCG | TPH2 | OR=3.35 OR=3.35 | The ORs and frequenc...... The ORs and frequencies in cases and controls indicate that the haplotypes ACCA and ACCG are associated with the BPI disorder. More... | Positive |
| Grigoroiu-Serbanescu, M.,2008 | rs1386497 - rs11834097 - rs4760820 - rs17722134 | ATCA ATCA | TPH2 | OR=0.8 OR=0.8 | Negative | |
| Grigoroiu-Serbanescu, M.,2008 | rs1386497 - rs11834097 - rs4760820 - rs17722134 | ACGA ACGA | TPH2 | OR=0.79 OR=0.79 | Negative | |
| Grigoroiu-Serbanescu, M.,2008 | rs1386497 - rs11834097 - rs4760820 - rs17722134 | CCCA CCCA | TPH2 | OR=1.05 OR=1.05 | Negative | |
| Chen, S., 2014 | rs1386494 - rs2171363 - rs4760816 | C-A-C C-A-C | TPH2 | Global P-value=0.706...... Global P-value=0.706, Chi2=0.001, P-value=0.973735. More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Chen, S., 2014 | rs1386494 - rs2171363 - rs4760816 | C-G-T C-G-T | TPH2 | Global P-value=0.706...... Global P-value=0.706, Chi2=0.134, P-value=0.713896. More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Chen, S., 2014 | rs1386494 - rs2171363 - rs4760816 | T-A-C T-A-C | TPH2 | Global P-value=0.706...... Global P-value=0.706, Chi2=0.666, P-value=0.414522. More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Lopez, V. A., 2007 | rs1386494 - rs1007023 - rs9325202 | G-T-G G-T-G | TPH2 | FBAT P-value = 0.983...... FBAT P-value = 0.983, Z=0.02, global P-value = 0.0396, X<sup>2</sup>(4)=10.051 in the NIMH 'Wave 3' Sample; FBAT P-value = 0.21, Z=-1.236, global P-value = 0.04 in the replication sample; FBAT global P-value = 0.0124 in the total sample More... | Three-marker haploty...... Three-marker haplotype tests revealed significant global association with BPAD in the NIMH 'Wave 3' Sample; FBAT again detected significant global association with BPAD in the total sample More... | Negative |
| Lopez, V. A., 2007 | rs1386494 - rs1007023 - rs9325202 | G-T-A G-T-A | TPH2 | FBAT P-value = 0.034...... FBAT P-value = 0.034, Z=2.12, global P-value = 0.0396, X<sup>2</sup>(4)=10.051 in the NIMH 'Wave 3' Sample; FBAT P-value = 0.04, Z=2.012, global P-value = 0.04 in the replication sample; TDTPHASE OR=1.07, 95% CI=0.865-1.138 for G-T-A haplotype; FBAT global P-value = 0.0124 in the total sample More... | Three-marker haploty...... Three-marker haplotype tests revealed significant global association with BPAD in the NIMH 'Wave 3' Sample; the over-transmitted haplotype that contributed to this association was predominantly G-T-A; there was significant overtransmission of the G-T-A haplotype to offspring with BPAD in the replication test; FBAT again detected significant global association with BPAD in the total sample More... | Positive |
| Lopez, V. A., 2007 | rs1386494 - rs1007023 - rs9325202 | A-G-A A-G-A | TPH2 | FBAT P-value = 0.087...... FBAT P-value = 0.087, Z=-1.708, global P-value = 0.0396, X<sup>2</sup>(4)=10.051 in the NIMH 'Wave 3' Sample; FBAT P-value = 0.63, Z=-0.479, global P-value = 0.04 in the replication sample; FBAT global P-value = 0.0124 in the total sample More... | Three-marker haploty...... Three-marker haplotype tests revealed significant global association with BPAD in the NIMH 'Wave 3' Sample; FBAT again detected significant global association with BPAD in the total sample More... | Negative |
| Gonzalez SD, 2013 | rs1380455 - rs16914968 - rs1551684 - rs3808942 - rs3808943 - rs10994336 | T-C-C-T-T-T T-C-C-T-T-T | ANK3 | FBAT P-value=0.023, ...... FBAT P-value=0.023, Permutation P-value=0.035, Z-score=2.266 More... | The TCCTTT haplotype...... The TCCTTT haplotype showed an over-transmission in BP, which was statistically significant after permutation test with 10 000 simulations. More... | Positive |
| Gonzalez SD, 2013 | rs1380455 - rs16914968 - rs1551684 - rs3808942 - rs3808943 - rs10994336 | G-C-C-T-C-C G-C-C-T-C-C | ANK3 | FBAT P-value=0.116, ...... FBAT P-value=0.116, Permutation P-value=0.126, Z-score=-1.572 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Gonzalez SD, 2013 | rs1380455 - rs16914968 - rs1551684 - rs3808942 - rs3808943 - rs10994336 | T-C-C-C-C-C T-C-C-C-C-C | ANK3 | FBAT P-value=0.572, ...... FBAT P-value=0.572, Permutation P-value=0.552, Z-score=-0.565 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Gonzalez SD, 2013 | rs1380455 - rs16914968 - rs1551684 - rs3808942 - rs3808943 - rs10994336 | T-C-T-T-C-C T-C-T-T-C-C | ANK3 | FBAT P-value=0.436, ...... FBAT P-value=0.436, Permutation P-value=0.396, Z-score=-0.778 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Gonzalez SD, 2013 | rs1380455 - rs16914968 - rs1551684 - rs3808942 - rs3808943 - rs10994336 | T-T-C-T-C-C T-T-C-T-C-C | ANK3 | FBAT P-value=0.082, ...... FBAT P-value=0.082, Permutation P-value=0.079, Z-score=1.737 More... | No significant assoc...... No significant association was observed. More... | Negative |
| Severinsen, J. E., 2006 (b) | rs137932 - rs137931 - rs6010260 - rs138881 | MLC1 BRD1 | P-value = 0.2014 in ...... P-value = 0.2014 in BD, P-value = 0.3061 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs137932 - rs137931 - rs6010260 | MLC1 | P-value = 0.3976 in ...... P-value = 0.3976 in BD, P-value = 0.4051 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs137932 - rs137931 | MLC1 | P-value = 0.8343 in ...... P-value = 0.8343 in BD, P-value = 0.921 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs137931 - rs6010260 - rs138881 - rs138880 | MLC1 BRD1 | P-value = 0.443 in B...... P-value = 0.443 in BD, P-value = 0.2358 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs137931 - rs6010260 - rs138881 | MLC1 BRD1 | P-value = 0.1011 in ...... P-value = 0.1011 in BD, P-value = 0.1926 in BD and SZ More... | Negative | ||
| Severinsen, J. E., 2006 (b) | rs137931 - rs6010260 | MLC1 | P-value = 0.2795 in ...... P-value = 0.2795 in BD, P-value = 0.1604 in BD and SZ More... | Negative | ||
| Feng, Y., 2008 | rs1369430 - rs1435403 - rs3784441 | NTRK3 | Global X<sup>2...... Global X<sup>2</sup>=17.588, df=7, p=0.014. For haplotypes with frequencies greater than 10%, X<sup>2</sup>=11.262, df=2, p=0.004. More... | Positive | ||
| Feng, Y., 2008 | rs1369430 - rs1435403 - rs3784441 | AGG AGG | NTRK3 | haplotype AGG P-valu...... haplotype AGG P-value = 0.002, X<sup>2</sup>(df=1)=9.704 More... | the common haplotype...... the common haplotype (frequency 0.62) was overtransmitted to affected offspring More... | Positive |
| Feng, Y., 2008 | rs1369430 - rs1435403 - rs3784441 | GAA GAA | NTRK3 | haplotype GAA P-valu...... haplotype GAA P-value = 0.095, X<sup>2</sup>(df=1)=2.789 More... | Negative | |
| Szczepankiewicz A., 2014 | rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 | A-C-G-C-C-A-C A-C-G-C-C-A-C | FKBP5 | P-value=0.429 P-value=0.429 | For BD patients we h...... For BD patients we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz A., 2014 | rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 | C-C-A-T-T-G-T C-C-A-T-T-G-T | FKBP5 | P-value=0.528 P-value=0.528 | For BD patients we h...... For BD patients we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz A., 2014 | rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 | C-T-A-C-T-G-T C-T-A-C-T-G-T | FKBP5 | P-value=0.771 P-value=0.771 | For BD patients we h...... For BD patients we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz A., 2014 | rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 | A-C-G-C-C-G-T A-C-G-C-C-G-T | FKBP5 | P-value=0.222 P-value=0.222 | For BD patients we h...... For BD patients we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz A., 2014 | rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 | C-C-A-C-T-A-T C-C-A-C-T-A-T | FKBP5 | P-value=0.249 P-value=0.249 | For BD patients we h...... For BD patients we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz A., 2014 | rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 | C-C-A-C-T-G-T C-C-A-C-T-G-T | FKBP5 | P-value=0.310 P-value=0.310 | For BD patients we h...... For BD patients we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz A., 2014 | rs1360780 - rs755658 - rs9470080 - rs7748266 - rs9296158 - rs9394309 - rs3800373 | A-C-A-T-T-G-T A-C-A-T-T-G-T | FKBP5 | P-value=0.218 P-value=0.218 | For BD patients we h...... For BD patients we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Palo, O. M.,2010 | rs1359885 - rs954779 | C-G C-G | RNF38 | Haplotypic associati...... Haplotypic association:Z-score=-0.543, FBAT P-value = 0.586 More... | No significant asso...... No significant association was found . More... | Negative |
| Roche, S.,2009 | rs1352250 - rs9325202 | A-A A-A | TPH2 | haplotype:X<sup&g...... haplotype:X<sup>2</sup>=1.574, Individual P-value =0.2097 More... | No significant asso...... No significant association was found . More... | Negative |
| Roche, S.,2009 | rs1352250 - rs9325202 | A-G A-G | TPH2 | haplotype:X<sup&g...... haplotype:X<sup>2</sup>=0.967, Individual P-value =0.3255 More... | No significant asso...... No significant association was found . More... | Negative |
| Roche, S.,2009 | rs1352250 - rs9325202 | G-G G-G | TPH2 | haplotype:X<sup&g...... haplotype:X<sup>2</sup>=2.099, Individual P-value =0.1474 More... | No significant asso...... No significant association was found . More... | Negative |
| Schulze, T. G.,2005 | rs1341402 - rs2391191 - rs3918342 - rs1421292 | G-G-C-T G-G-C-T | DAOA | For German group :Al...... For German group :All Patients With Bipolar Affective Disorder, P-value > 0.05 , OR=1.29 More... | No significant asso...... No significant association was found . More... | Negative |
| Schulze, T. G.,2005 | rs1341402 - rs2391191 - rs3918342 - rs1421292 | G-G-T-A G-G-T-A | DAOA | For German group :Al...... For German group :All Patients With Bipolar Affective Disorder, P-value < 0.05 , OR=0.73 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Muller, D. J.,2011 | rs1341402 - rs2391191 - rs1935062 - rs947267 - rs778294 | T-A-C-T-C T-A-C-T-C | DAOA | FBAT:for total sampl...... FBAT:for total sample, variance of the S-statistic=47.4, Z-score=-2.48, P-value = 0.01, global P-value = 0.42; for European sample, variance of the S-statistic=44.4, Z-score=-3, P-value = 0.003, global P-value = 0.24 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Muller, D. J.,2011 | rs1341402 - rs2391191 - rs1935062 - rs947267 | T-A-C-T T-A-C-T | DAOA | FBAT:for total sampl...... FBAT:for total sample, variance of the S-statistic=47.3, Z-score=-2.46, P-value = 0.01, global P-value = 0.39; for European sample, variance of the S-statistic=44.3, Z-score=-2.99, P-value = 0.003, global P-value = 0.15 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Muller, D. J.,2011 | rs1341402 - rs2391191 - rs1935062 | T-A-C T-A-C | DAOA | FBAT:for total sampl...... FBAT:for total sample, variance of the S-statistic=52.1, Z-score=-2.17, P-value = 0.03, global P-value = 0.23; for European sample, variance of the S-statistic=48.7, Z-score=-2.61, P-value = 0.009, global P-value = 0.11 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Palo, O. M.,2010 | rs1332184 - rs720974 | G-C G-C | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=0.716, FBAT P-value = 0.474 More... | No significant asso...... No significant association was found . More... | Negative |
| Severinsen, J. E., 2006 (a) | rs133073 - rs133070 - rs133069 - rs133068 | MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.0479, CLUMP T4 P-value = 0.1278 in BPD and SZ, CLUMP T1 P-value = 0.0433, CLUMP T4 P-value = 0.0997 in BPD; Empirical overall P-value = 0.0184 in BPD and SZ, Empirical overall P-value = 0.0003 in BPD More... | Similarly, comparing...... Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL. More... | Positive | |
| Severinsen, J. E., 2006 (a) | rs133073 - rs133070 - rs133069 | MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.0268, CLUMP T4 P-value = 0.0626 in BPD and SZ, CLUMP T1 P-value = 0.0042, CLUMP T4 P-value = 0.0303 in BPD; Empirical overall P-value = 0.0155 in BPD and SZ, Empirical overall P-value = 0.0053 in BPD More... | Similarly, comparing...... Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL. More... | Positive | |
| Severinsen, J. E., 2006 (a) | rs133073 - rs133070 - rs133069 - rs133068 - D22S279 | MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.0063, CLUMP T4 P-value = 0.0023 in BPD and SZ, CLUMP T1 P-value = 0.1521, CLUMP T4 P-value = 0.1056 in BPD; Empirical overall P-value = 0.1747 in BPD and SZ, Empirical overall P-value = 0.041 in BPD More... | Similarly, comparing...... Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL. More... | Positive | |
| Severinsen, J. E., 2006 (a) | rs133073 - rs133070 | MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.004, CLUMP T4 P-value = 0.0188 in BPD and SZ, CLUMP T1 P-value = 0.0009, CLUMP T4 P-value = 0.0093 in BPD; Empirical overall P-value = 0.0262 in BPD and SZ, Empirical overall P-value = 0.1471 in BPD More... | The strongest signal...... The strongest signal was centered on 2-marker haplotypes from rs133069 to rs133073 in GPR24. Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL. More... | Positive | |
| Severinsen, J. E., 2006 (a) | rs133070 - rs133073 | A-C A-C | MCHR1 | CLUMP P-value = 0.00...... CLUMP P-value = 0.0048 in BPD, P-value = 0.0234 in BPD and SZ; risk haplotype More... | The overall signal i...... The overall signal in BPD was strongest for 2- and 3-marker haplotypes involving rs133069 to rs133073. The same specific 2- and 3-marker haplotypes covering rs133069 to rs133073 as seen in BPD showed P-values as low as 0.0183 in the combined sample. More... | Positive |
| Severinsen, J. E., 2006 (a) | rs133070 - rs133073 | G-C G-C | MCHR1 | CLUMP P-value = 0.01...... CLUMP P-value = 0.0165 in BPD, P-value = 0.0183 in BPD and SZ; protective haplotype More... | The overall signal i...... The overall signal in BPD was strongest for 2- and 3-marker haplotypes involving rs133069 to rs133073. The same specific 2- and 3-marker haplotypes covering rs133069 to rs133073 as seen in BPD showed P-values as low as 0.0183 in the combined sample. More... | Positive |
| Severinsen, J. E., 2006 (a) | rs133070 - rs133069 - rs133068 - D22S279 - rs909669 | MCHR1 ADSL | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.0059, CLUMP T4 P-value = 0.0031 in BPD and SZ, CLUMP T1 P-value = 0.2957, CLUMP T4 P-value = 0.1557 in BPD; Empirical overall P-value = 0.339 in BPD and SZ, Empirical overall P-value = 0.4471 in BPD More... | Positive | ||
| Severinsen, J. E., 2006 (a) | rs133070 - rs133069 - rs133068 - D22S279 | MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.0064, CLUMP T4 P-value = 0.0023 in BPD and SZ, CLUMP T1 P-value = 0.1531, CLUMP T4 P-value = 0.1076 in BPD; Empirical overall P-value = 0.3363 in BPD and SZ, Empirical overall P-value = 0.3612 in BPD More... | Similarly, comparing...... Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL. More... | Positive | |
| Severinsen, J. E., 2006 (a) | rs133070 - rs133069 - rs133068 | MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.0525, CLUMP T4 P-value = 0.1831 in BPD and SZ, CLUMP T1 P-value = 0.0316, CLUMP T4 P-value = 0.0972 in BPD; Empirical overall P-value = 0.5945 in BPD and SZ, Empirical overall P-value = 0.0779 in BPD More... | Similarly, comparing...... Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL. More... | Positive | |
| Severinsen, J. E., 2006 (a) | rs133070 - rs133069 | MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.0145, CLUMP T4 P-value = 0.0828 in BPD and SZ, CLUMP T1 P-value = 0.003, CLUMP T4 P-value = 0.0159 in BPD; Empirical overall P-value = 0.4592 in BPD and SZ, Empirical overall P-value = 0.1855 in BPD More... | The strongest signal...... The strongest signal was centered on 2-marker haplotypes from rs133069 to rs133073 in GPR24. Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL. More... | Positive | |
| Severinsen, J. E., 2006 (a) | rs133069 - rs133070 - rs133073 | A-G-C A-G-C | MCHR1 | CLUMP P-value = 0.03...... CLUMP P-value = 0.0307 in BPD, P-value = 0.0526 in BPD and SZ; protective haplotype More... | The overall signal i...... The overall signal in BPD was strongest for 2- and 3-marker haplotypes involving rs133069 to rs133073. The same specific 2- and 3-marker haplotypes covering rs133069 to rs133073 as seen in BPD showed P-values as low as 0.0183 in the combined sample. More... | Positive |
| Severinsen, J. E., 2006 (a) | rs133069 - rs133070 | A-G A-G | MCHR1 | CLUMP P-value = 0.03...... CLUMP P-value = 0.0393 in BPD, P-value = 0.0364 in BPD and SZ; protective haplotype More... | The overall signal i...... The overall signal in BPD was strongest for 2- and 3-marker haplotypes involving rs133069 to rs133073. The same specific 2- and 3-marker haplotypes covering rs133069 to rs133073 as seen in BPD showed P-values as low as 0.0183 in the combined sample. More... | Positive |
| Severinsen, J. E., 2006 (a) | rs133069 - rs133068 - D22S279 - rs909669 | MCHR1 ADSL | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.2672, CLUMP T4 P-value = 0.2064 in BPD and SZ, CLUMP T1 P-value = 0.7976, CLUMP T4 P-value = 0.5424 in BPD; Empirical overall P-value = 0.0591 in BPD and SZ, Empirical overall P-value = 0.5948 in BPD More... | Negative | ||
| Severinsen, J. E., 2006 (a) | rs133069 - rs133068 - D22S279 | MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.2017, CLUMP T4 P-value = 0.2023 in BPD and SZ, CLUMP T1 P-value = 0.5063, CLUMP T4 P-value = 0.4663 in BPD; Empirical overall P-value = 0.3066 in BPD and SZ, Empirical overall P-value = 0.7233 in BPD More... | Negative | ||
| Severinsen, J. E., 2006 (a) | rs133069 - rs133068 | MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.0716, CLUMP T4 P-value = 0.1107 in BPD and SZ, CLUMP T1 P-value = 0.6484, CLUMP T4 P-value = 0.5936 in BPD; Empirical overall P-value = 0.1791 in BPD and SZ, Empirical overall P-value = 0.3582 in BPD More... | Negative | ||
| Severinsen, J. E., 2006 (a) | rs133068 - D22S279 - rs909669 | MCHR1 ADSL | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.4823, CLUMP T4 P-value = 0.3996 in BPD and SZ, CLUMP T1 P-value = 0.8745, CLUMP T4 P-value = 0.7353 in BPD; Empirical overall P-value = 0.0319 in BPD and SZ, Empirical overall P-value = 0.3278 in BPD More... | Similarly, comparing...... Similarly, comparing controls to the combined group of cases revealed significant associations with 2-, 3-, 4-, and 5-marker haplotypes spanning the SNPs in GPR24 as well as rs909669 in ADSL. More... | Positive | |
| Severinsen, J. E., 2006 (a) | rs133068 - D22S279 | MCHR1 | CLUMP T1 P-value = 0...... CLUMP T1 P-value = 0.1818, CLUMP T4 P-value = 0.127 in BPD and SZ, CLUMP T1 P-value = 0.4893, CLUMP T4 P-value = 0.5473 in BPD; Empirical overall P-value = 0.1821 in BPD and SZ, Empirical overall P-value = 0.6295 in BPD More... | Negative | ||
| Palo, O. M., 2007 | rs1322784 - rs967244 | A-G A-G | DISC1 | Individual P-value =...... Individual P-value = 0.517 in all, P-value = 0.966 in males, P-value = 0.243 in females; global P-value = 0.849 in all, P-value = 0.819 in males, P-value = 0.338 in females, with bipolar spectrum disorder More... | Negative | |
| Palo, O. M.,2010 | rs1320393 - rs1880180 | G-A G-A | SLC13A1 | Haplotypic associati...... Haplotypic association:Z-score=-1.204, FBAT P-value = 0.228 More... | No significant asso...... No significant association was found . More... | Negative |
| Kishi, T.,2009(c) | rs1316780 - rs10865660 - rs3796224 - rs1374913 | PROK2 | likelihood ratio tes...... likelihood ratio test:Global P-value = 0.455 in BP More... | No significant asso...... No significant association was found with BP. More... | Negative | |
| Severino, G.,2009 | rs12941497 - rs939347 | A-A A-A | NR1D1 | haplotype:Individual...... haplotype:Individual P-value =0.531 More... | No significant asso...... No significant association was found . More... | Negative |
| Severino, G.,2009 | rs12941497 - rs939347 | A-G A-G | NR1D1 | haplotype:Individual...... haplotype:Individual P-value =0.012 More... | Significant associat...... Significant association was found. More... | Positive |
| Severino, G.,2009 | rs12941497 - rs939347 | G-G G-G | NR1D1 | haplotype:Individual...... haplotype:Individual P-value =0.04 More... | Significant associat...... Significant association was found. More... | Positive |
| Szczepankiewicz, A., 2013 | rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 | C-C-G-C-C C-C-G-C-C | CRHR1 | P-value=0.75, X<s...... P-value=0.75, X<sup>2</sup>=0.101 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz, A., 2013 | rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 | C-T-A-C-G C-T-A-C-G | CRHR1 | P-value=0.297, X<...... P-value=0.297, X<sup>2</sup>=1.086 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz, A., 2013 | rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 | C-C-A-T-C C-C-A-T-C | CRHR1 | P-value=0.306, X<...... P-value=0.306, X<sup>2</sup>=1.048 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz, A., 2013 | rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 | C-C-A-C-C C-C-A-C-C | CRHR1 | P-value=0.454, X<...... P-value=0.454, X<sup>2</sup>=0.557 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz, A., 2013 | rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 | T-C-A-C-C T-C-A-C-C | CRHR1 | P-value=0.278, X<...... P-value=0.278, X<sup>2</sup>=1.175 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. More... | Negative |
| Szczepankiewicz, A., 2013 | rs12936511 - rs16940655 - rs173365 - rs242950 - rs878886 | C-C-A-C-G C-C-A-C-G | CRHR1 | P-value=0.031, X<...... P-value=0.031, X<sup>2</sup>=4.626 More... | For the MDD and bipo...... For the MDD and bipolar disorder patients, we have not observed any significant differences in haplotype frequencies. We observed that the CCACG haplotype in the second haplotype block was significantly more frequent in the patients with mood disorders than in healthy individuals (P=0.031); however, the difference was not observed after multiple testing correction (after 10 000 permutations, P=0.208). More... | Negative |
| He, B.,2009 | rs12885300 - rs225014 | DIO2 | haplotype analysis:(...... haplotype analysis:(C-T):X<sup>2</sup>=0.076, P-value = 0.783, Odds ratio [95% CI]=1.035 [0.810-1.323]; (T-C):X<sup>2</sup>=19.585, P-value = 9.83E-006, Odds ratio [95% CI]=3.759 [2.013-7.020]; (T-T):X<sup>2</sup>=31.861, P-value = 1.75E-008, Odds ratio [95% CI]=0.395 [0.284-0.549]; (C-C):X<sup>2</sup>=4.415, P-value = 0.036, Odds ratio [95% CI]=1.292 [1.017-1.642] More... | We found significan...... We found significant differences between cases and controls at haplotype(T-C), (T-T) and (C-C). More... | Positive | |
| Kishi, T.,2011(a) | rs12778366 - rs2273773 - rs4746720 - rs10997875 | C-T-T-T C-T-T-T | SIRT1 | Haplotype analysis:l...... Haplotype analysis:likelihood ratio test:X<sup>2</sup>(1df)=1.92, OR=0.508, 95%CI=0.335-0.771, individual P-value = 0.166 for BD More... | No significant asso...... No significant association was found . More... | Negative |
| Kishi, T.,2011(a) | rs12778366 - rs2273773 - rs4746720 - rs10997875 | T-C-T-T T-C-T-T | SIRT1 | Haplotype analysis:l...... Haplotype analysis:likelihood ratio test:X<sup>2</sup>(1df)=2.73, OR=0.5337, 95%CI=0.790-2.73, individual P-value = 0.0984 for BD More... | No significant asso...... No significant association was found . More... | Negative |
| Kishi, T.,2011(a) | rs12778366 - rs2273773 - rs4746720 - rs10997875 | T-T-C-T T-T-C-T | SIRT1 | Haplotype analysis:l...... Haplotype analysis:likelihood ratio test:X<sup>2</sup>(1df)=0.326, OR=0.582, 95%CI=0.394-0.859, individual P-value = 0.568 for BD More... | No significant asso...... No significant association was found . More... | Negative |
| Kishi, T.,2011(a) | rs12778366 - rs2273773 - rs4746720 - rs10997875 | T-T-T-C T-T-T-C | SIRT1 | Haplotype analysis:l...... Haplotype analysis:likelihood ratio test:X<sup>2</sup>(1df)=1.98, OR=0.623, 95%CI=0.416-0.929, individual P-value = 0.159 for BD More... | No significant asso...... No significant association was found . More... | Negative |
| Kishi, T.,2011(a) | rs12778366 - rs2273773 - rs4746720 - rs10997875 | T-T-T-T T-T-T-T | SIRT1 | Haplotype analysis:l...... Haplotype analysis:likelihood ratio test:X<sup>2</sup>(1df)=2.17, OR=1, 95%CI=1.00-1.00, individual P-value = 0.782 for BD More... | No significant asso...... No significant association was found . More... | Negative |
| Zhou, X.,2009 | rs12668354 - rs12673091 - rs1018954 - rs3735440 - rs11974306 | A-A-A-C-T A-A-A-C-T | SP4 | Haplotypic associati...... Haplotypic association:Global P-value = 0.004, Individual P-value = 0.585 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Zhou, X.,2009 | rs12668354 - rs12673091 - rs1018954 - rs3735440 - rs11974306 | A-A-A-T-A A-A-A-T-A | SP4 | Haplotypic associati...... Haplotypic association:Global P-value = 0.004, Individual P-value = 0.684 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Zhou, X.,2009 | rs12668354 - rs12673091 - rs1018954 - rs3735440 - rs11974306 | A-A-A-T-T A-A-A-T-T | SP4 | Haplotypic associati...... Haplotypic association:Global P-value = 0.004, Individual P-value = 0.511 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Zhou, X.,2009 | rs12668354 - rs12673091 - rs1018954 - rs3735440 - rs11974306 | A-G-A-T-A A-G-A-T-A | SP4 | Haplotypic associati...... Haplotypic association:Global P-value = 0.004, Individual P-value = 0.232 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Zhou, X.,2009 | rs12668354 - rs12673091 - rs1018954 - rs3735440 - rs11974306 | A-G-T-T-A A-G-T-T-A | SP4 | Haplotypic associati...... Haplotypic association:Global P-value = 0.004, Individual P-value = 0.0004 More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhou, X.,2009 | rs12668354 - rs12673091 - rs1018954 - rs3735440 - rs11974306 | A-G-T-T-T A-G-T-T-T | SP4 | Haplotypic associati...... Haplotypic association:Global P-value = 0.004, Individual P-value = 0.907 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Zhou, X.,2009 | rs12668354 - rs12673091 - rs1018954 - rs3735440 - rs11974306 | C-A-T-C-T C-A-T-C-T | SP4 | Haplotypic associati...... Haplotypic association:Global P-value = 0.004, Individual P-value = 0.019 More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhou, X.,2009 | rs12668354 - rs12673091 - rs1018954 - rs3735440 | A-A-A-T A-A-A-T | SP4 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.03 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Zhou, X.,2009 | rs12668354 - rs12673091 - rs1018954 - rs3735440 | A-G-T-T A-G-T-T | SP4 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.04 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Zhou, X.,2009 | rs12668354 - rs12673091 - rs1018954 - rs3735440 | C-A-T-C C-A-T-C | SP4 | Haplotypic associati...... Haplotypic association:Individual P-value = 0.027 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Gaysina, D.,2010 | rs12584489 - rs2391191 - rs9558562 | DAOA | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=1.22, P-value = 0.57 for UK sample; X<sup>2</sup>=0.74, P-value = 0.69 for Canadian sample. More... | No significant asso...... No significant association was found . More... | Negative | |
| Cao L., 2014 | rs12547858 - rs2439273 | A-A A-A | NRG1 | Globe: X<sup>2...... Globe: X<sup>2</sup>=16.52, Bonf P-value=0.035; A-A: X<sup>2</sup>=13.85, Bonf P-value=0.027 More... | likely supporting th...... likely supporting the association between this NRG1 region and BPI. More... | Positive |
| Palo, O. M.,2010 | rs12217 - rs1320393 | G-A G-A | AASS, SLC13A1 | Haplotypic associati...... Haplotypic association:Z-score=1.54, FBAT P-value = 0.123 More... | No significant asso...... No significant association was found . More... | Negative |
| Palo, O. M.,2010 | rs1220087 - rs666478 | A-G A-G | TEK | Haplotypic associati...... Haplotypic association:Z-score=4.405, FBAT P-value = 0.00001 More... | Significant associat...... Significant association was found. More... | Positive |
| Schosser, A., 2010 | rs12133766 - rs1000731 - rs7546310 | GAC GAC | DISC1 | Individual P-value =...... Individual P-value = 0.004, global P-value = 0.06 More... | Positive | |
| Schosser, A., 2010 | rs12133766 - rs1000731 | GA GA | DISC1 | Individual P-value =...... Individual P-value = 0.1, global P-value = 0.25 More... | Negative | |
| Ross, K. A.,2011 | rs12070036 - rs9551988 | ZNF678 PSPC1 | SNP interactions:P-v...... SNP interactions:P-value = 0.09 More... | No significant asso...... No significant association was found . More... | Negative | |
| Ross, K. A.,2011 | rs12070036 - rs4850057 | ZNF678 | SNP interactions:P-v...... SNP interactions:P-value = 0.45 More... | No significant asso...... No significant association was found . More... | Negative | |
| Ross, K. A.,2011 | rs12070036 - rs2122231 | ZNF678 | SNP interactions:P-v...... SNP interactions:P-value = 0.72 More... | No significant asso...... No significant association was found . More... | Negative | |
| Ross, K. A.,2011 | rs12070036 - rs12227938 | ZNF678 | SNP interactions:P-v...... SNP interactions:P-value = 0.87 More... | No significant asso...... No significant association was found . More... | Negative | |
| Ross, K. A.,2011 | rs12070036 - (SNP A-1797773) | ZNF678 | SNP interactions:P-v...... SNP interactions:P-value = 0.00000000026 More... | Significant associat...... Significant association was found in BPD. More... | Positive | |
| Cao L., 2014 | rs12056925 - rs12547858 | A-A A-A | NRG1 | Globe: X<sup>2...... Globe: X<sup>2</sup>=17.16, Bonf P-value=0.025; A-A: X<sup>2</sup>=13.85, Bonf P-value=0.027 More... | All of these haploty...... All of these haplotypes were more common in controls than in BPI patients, suggesting that its presence might indicate a decreased risk of BPI. More... | Positive |
| Kishi, T.,2009(a) | rs11939815 - rs11931061 - rs11133385 - rs3736544 - rs1801260 - rs3749474 | CLOCK | likelihood ratio tes...... likelihood ratio test:haplotype(G-A-A-G-T-T):1.total samples:Global P-value = 0.957 in BP 2. male samples:Global P-value = 0.899 in BP 3. female samples:Global P-value = 0.919 in BP More... | No significant asso...... No significant association was found with BP. More... | Negative | |
| Dmitrzak-Weglarz, M. P., 2014 | rs11824092 - rs1982350 | C-G C-G | ARNTL | BD: Case frequency=0...... BD: Case frequency=0.625, control frequency=0.561; Chi square=4.787, P-value=0.028 More... | Significant associat...... Significant association between this block and BD was observed. More... | Positive |
| Dmitrzak-Weglarz, M. P., 2014 | rs11824092 - rs1982350 | T-A T-A | ARNTL | BD: Case frequency=0...... BD: Case frequency=0.363, control frequency=0.415; Chi square=3.24, P-value=0.071 More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Dmitrzak-Weglarz, M. P., 2014 | rs11824092 - rs1982350 | C-A C-A | ARNTL | BD: Case frequency=0...... BD: Case frequency=0.008, control frequency=0.015; Chi square=1.322, P-value=0.250 More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Li, J.,2011(a) | rs11759115 - rs7769372 | C-C C-C | MDGA1 | Haplotype analysis:f...... Haplotype analysis:for BP, global P-value = 0.9085, individual P-value = 0.9311 More... | No significant asso...... No significant association was found . More... | Negative |
| Li, J.,2011(a) | rs11759115 - rs7769372 | T-C T-C | MDGA1 | Haplotype analysis:f...... Haplotype analysis:for BP, global P-value = 0.9085, individual P-value = 0.6157 More... | No significant asso...... No significant association was found . More... | Negative |
| Li, J.,2011(a) | rs11759115 - rs7769372 | T-T T-T | MDGA1 | Haplotype analysis:f...... Haplotype analysis:for BP, global P-value = 0.9085, individual P-value = 0.8619 More... | No significant asso...... No significant association was found . More... | Negative |
| Underwood, S. L., 2006 | rs11736084 - rs1282 - rs17844778 - rs9685931 - rs9799720 | T-C-C-G-C T-C-C-G-C | GPR78 | Global test P-value ...... Global test P-value (permuted P-value, s.e.)=0.017 (0.033, 0.002), Individual test P-value (permuted P-value, s.e.)=0.004 (0.070, 0.003), OR (95% CI)=0.562 (0.375-0.842) in all female affected; Global test P-value (permuted P-value, s.e.)=0.016 (0.032, 0.002), Individual test P-value (permuted P-value, s.e.)=0.005 (0.101, 0.003), OR (95% CI)=0.514 (0.323-0.818) in female BPAD More... | No haplotype tested ...... No haplotype tested by either the global or individual test maintained its significance after permutation analysis. However, the global test P-values of two related haplotypes remained significant in both the BPAD females and all affected females. More... | Positive |
| Underwood, S. L., 2006 | rs11736084 - rs1282 - rs17844778 - rs9685931 | T-C-C-G T-C-C-G | GPR78 | Global test P-value ...... Global test P-value (permuted P-value, s.e.)=0.015 (0.044, 0.002), Individual test P-value (permuted P-value, s.e.)=0.003 (0.048, 0.002), OR (95% CI)=0.547 (0.367-0.815) in all female affected; Global test P-value (permuted P-value, s.e.)=0.013 (0.038, 0.002), Individual test P-value (permuted P-value, s.e.)=0.004 (0.066, 0.002), OR (95% CI)=0.496 (0.313-0.785) in female BPAD More... | No haplotype tested ...... No haplotype tested by either the global or individual test maintained its significance after permutation analysis. However, the global test P-values of two related haplotypes remained significant in both the BPAD females and all affected females. More... | Positive |
| Zeng, Z.,2011 | rs1170099 - rs9566940 | A-C A-C | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.5, permutated P-value = 0.999 for BPD; P-value = 0.548, permutated P-value = 1 for BPDI More... | No significant asso...... No significant association was found . More... | Negative |
| Zeng, Z.,2011 | rs1170099 - rs9566940 | A-T A-T | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.519, permutated P-value = 1 for BPD; P-value = 0.547, permutated P-value = 1 for BPDI More... | No significant asso...... No significant association was found . More... | Negative |
| Zeng, Z.,2011 | rs1170099 - rs9566940 | G-T G-T | DGKH | Haplotypic associati...... Haplotypic association:P-value = 0.04, permutated P-value = 0.262 for BPD; P-value = 0.082, permutated P-value = 0.522 for BPDI More... | No significant asso...... No significant association was found . More... | Negative |
| Kakiuchi, C., 2007 (a) | rs1165687 - rs1882019 - rs17034977 - rs703657 - rs2293618 | C-A-A-T-T C-A-A-T-T | HSP90B1 | P-value = 0.27 in MD...... P-value = 0.27 in MDMD samples, P-value = 0.72 in MPS samples, P-value = 0.31 in Total samples; COCAPHASE global P-value = 0.037 in MDMD samples, COCAPHASE global P-value = 0.071 in MPS samples, COCAPHASE global P-value = 0.0026 in Total samples More... | no significant assoc...... no significant association with bipolar disorder was reported More... | Negative |
| Kakiuchi, C., 2007 (a) | rs1165687 - rs1882019 - rs17034977 - rs703657 - rs2293618 | C-G-A-A-C C-G-A-A-C | HSP90B1 | P-value = 0.35 in MD...... P-value = 0.35 in MDMD samples, P-value = 0.15 in MPS samples, P-value = 0.094 in Total samples; COCAPHASE global P-value = 0.037 in MDMD samples, COCAPHASE global P-value = 0.071 in MPS samples, COCAPHASE global P-value = 0.0026 in Total samples More... | no significant assoc...... no significant association with bipolar disorder was reported More... | Negative |
| Kakiuchi, C., 2007 (a) | rs1165687 - rs1882019 - rs17034977 - rs703657 - rs2293618 | C-G-C-T-T C-G-C-T-T | HSP90B1 | P-value = 0.012 in M...... P-value = 0.012 in MDMD samples, P-value = 0.027 in MPS samples, P-value = 0.00094 in Total samples; COCAPHASE global P-value = 0.037 in MDMD samples, COCAPHASE global P-value = 0.071 in MPS samples, COCAPHASE global P-value = 0.0026 in Total samples More... | CGCTT was significan...... CGCTT was significantly associated with bipolar disorder More... | Positive |
| Dmitrzak-Weglarz, M. P., 2014 | rs11600996 - rs11022779 - rs11022780 | C-G-T C-G-T | ARNTL | BD: Case frequency=0...... BD: Case frequency=0.606, control frequency=0.534; Chi square=6.087, P-value=0.013. BD I: Case frequency=0.596, control frequency=0.543; Chi square=5.432, P-value=0.0198. BD II: Case frequency=0.633, control frequency=0.543; Chi square=6.463, P-value=0.011 More... | Significant associat...... Significant association between this block and BD was observed. More... | Positive |
| Dmitrzak-Weglarz, M. P., 2014 | rs11600996 - rs11022779 - rs11022780 | T-G-C T-G-C | ARNTL | BD: Case frequency=0...... BD: Case frequency=0.226, control frequency=0.289; Chi square=5.935, P-value=0.014. BD I: Case frequency=0.233, control frequency=0.270; Chi square=3.369, P-value=0.0664. BD II: Case frequency=0.206, control frequency=0.270; Chi square=4.235, P-value=0.0396 More... | We also found out AR...... We also found out ARNTL gene TGC haplotype of the (P-value=0.014) potentially protective against BPD. More... | Positive |
| Dmitrzak-Weglarz, M. P., 2014 | rs11600996 - rs11022779 - rs11022780 | T-A-C T-A-C | ARNTL | BD: Case frequency=0...... BD: Case frequency=0.166, control frequency=0.171; Chi square=0.043, P-value=0.836. BD I: Case frequency=0.169, control frequency=0.181; Chi square=0.476, P-value=0.4902. BD II: Case frequency=0.157, control frequency=0.181; Chi square=0.809, P-value=0.3685 More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Doyle, G. A.,2011 | rs1156044 - rs906807 | A-C A-C | NDUFV2 | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=7.033, P-value = 0.008 after Bonferroni correction; lowest permutation adjusted P-value = 0.064 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Doyle, G. A.,2011 | rs1156044 - rs906807 | A-T A-T | NDUFV2 | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=1.259, P-value = 0.262 More... | No significant assoc...... No significant association was observed in BPDI. More... | Negative |
| Doyle, G. A.,2011 | rs1156044 - rs906807 | G-T G-T | NDUFV2 | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup>=2.765, P-value = 0.096 More... | No significant assoc...... No significant association was observed in BPDI. More... | Negative |
| Kakiuchi, C., 2007 (b) | rs1152230 - rs283524 - rs283525 - rs8647 - rs8667 | ATF5 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.5119 in Japanese samples; TDT P-value = 0.08347 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Kakiuchi, C., 2007 (b) | rs1152230 - rs283524 - rs283525 - rs8647 | ATF5 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.4602 in Japanese samples; TDT P-value = 0.08347 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Kakiuchi, C., 2007 (b) | rs1152230 - rs283524 - rs283525 | ATF5 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.4677 in Japanese samples; TDT P-value = 0.1915 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Kakiuchi, C., 2007 (b) | rs1152230 - rs283524 | ATF5 | COCAPHASE global P-v...... COCAPHASE global P-value = 0.3182 in Japanese samples; TDT P-value = 0.8767 in NIMH samples More... | Haplotype analysis d...... Haplotype analysis did not show significant difference in both of the ethnicities. More... | Negative | |
| Pisanu, C., 2013 | rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583 | A-A-A-A-C A-A-A-A-C | NAPEPLD | P-value=0.742, X<...... P-value=0.742, X<sup>2</sup>=0.11 More... | It showed no nominal...... It showed no nominal association with BD. More... | Negative |
| Pisanu, C., 2013 | rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583 | A-G-A-A-C A-G-A-A-C | NAPEPLD | P-value=0.227, X<...... P-value=0.227, X<sup>2</sup>=1.46 More... | It showed no nominal...... It showed no nominal association with BD. More... | Negative |
| Pisanu, C., 2013 | rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583 | T-A-C-A-A T-A-C-A-A | NAPEPLD | P-value=0.011, X<...... P-value=0.011, X<sup>2</sup>=6.42 More... | Of the 6 possible co...... Of the 6 possible combinations of NAPE-PLD, only haplotype TACAA showed nominal association with BD, but not with lithium response. More... | Positive |
| Pisanu, C., 2013 | rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583 | T-A-A-C-C T-A-A-C-C | NAPEPLD | P-value=0.379, X<...... P-value=0.379, X<sup>2</sup>=0.78 More... | It showed no nominal...... It showed no nominal association with BD. More... | Negative |
| Pisanu, C., 2013 | rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583 | T-A-A-A-C T-A-A-A-C | NAPEPLD | P-value=0.883, X<...... P-value=0.883, X<sup>2</sup>=0.02 More... | It showed no nominal...... It showed no nominal association with BD. More... | Negative |
| Pisanu, C., 2013 | rs11487077 - rs6465903 - rs13232194 - rs17605251 - rs12540583 | T-A-A-A-A T-A-A-A-A | NAPEPLD | P-value=0.611, X<...... P-value=0.611, X<sup>2</sup>=0.26 More... | It showed no nominal...... It showed no nominal association with BD. More... | Negative |
| Schosser, A.,2011 | rs1134986 - rs338217 | DLG1 | Haplotype analysis:i...... Haplotype analysis:individual P-value = 0.447, global P-value = 0.182 More... | No significant asso...... No significant association was found . More... | Negative | |
| Karege, F.,2010 | rs1130233 - rs3730358 - rs1130214 - rs3803300 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.216 More... | No significant asso...... No significant association was found . More... | Negative | |
| Karege, F.,2010 | rs1130233 - rs3730358 - rs1130214 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.346 More... | No significant asso...... No significant association was found . More... | Negative | |
| Karege, F.,2010 | rs1130233 - rs3730358 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.597 More... | No significant asso...... No significant association was found . More... | Negative | |
| Karege, F.,2010 | rs1130214 - rs3803300 | AKT1 | multi-locus associat...... multi-locus association analyses:global P-value = 0.143 More... | No significant asso...... No significant association was found . More... | Negative | |
| Palo, O. M.,2010 | rs1121030 - rs1860487 | A-G A-G | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=0.592, FBAT P-value = 0.554 More... | No significant asso...... No significant association was found . More... | Negative |
| Van Den Bogaert, A., 2006 (a) | rs11178997 - rs10748185 - rs2129575 - rs1843809 | T-A-G-T T-A-G-T | TPH2 | global P-value = 0.0...... global P-value = 0.02, P-value = 0.09 More... | We also observed dif...... We also observed differences in haplotype distribution between patients with BP disorder and control individuals in hapblock 2 (Pglobal=.02). This significant finding is the result of a decrease in the frequency of haplotype TGTT, from 25% in control individuals to 15% in patients with BP disorder (Pspecific=.002). More... | Negative |
| Van Den Bogaert, A., 2006 (a) | rs11178997 - rs10748185 - rs2129575 - rs1843809 | T-G-T-T T-G-T-T | TPH2 | global P-value = 0.0...... global P-value = 0.02, P-value = 0.002 More... | We also observed dif...... We also observed differences in haplotype distribution between patients with BP disorder and control individuals in hapblock 2 (Pglobal=.02). This significant finding is the result of a decrease in the frequency of haplotype TGTT, from 25% in control individuals to 15% in patients with BP disorder (Pspecific=.002). More... | Positive |
| Van Den Bogaert, A., 2006 (a) | rs11178997 - rs10748185 - rs2129575 - rs1843809 | T-G-G-T T-G-G-T | TPH2 | global P-value = 0.0...... global P-value = 0.02, P-value = 0.74 More... | We also observed dif...... We also observed differences in haplotype distribution between patients with BP disorder and control individuals in hapblock 2 (Pglobal=.02). This significant finding is the result of a decrease in the frequency of haplotype TGTT, from 25% in control individuals to 15% in patients with BP disorder (Pspecific=.002). More... | Negative |
| Van Den Bogaert, A., 2006 (a) | rs11178997 - rs10748185 - rs2129575 - rs1843809 | T-G-G-G T-G-G-G | TPH2 | global P-value = 0.0...... global P-value = 0.02, P-value = 0.41 More... | We also observed dif...... We also observed differences in haplotype distribution between patients with BP disorder and control individuals in hapblock 2 (Pglobal=.02). This significant finding is the result of a decrease in the frequency of haplotype TGTT, from 25% in control individuals to 15% in patients with BP disorder (Pspecific=.002). More... | Negative |
| Van Den Bogaert, A., 2006 (a) | rs11178997 - rs10748185 - rs2129575 - rs1843809 | A-G-T-T A-G-T-T | TPH2 | global P-value = 0.0...... global P-value = 0.02, P-value = 0.17 More... | We also observed dif...... We also observed differences in haplotype distribution between patients with BP disorder and control individuals in hapblock 2 (Pglobal=.02). This significant finding is the result of a decrease in the frequency of haplotype TGTT, from 25% in control individuals to 15% in patients with BP disorder (Pspecific=.002). More... | Negative |
| Pereira, A. C.,2011 | rs11111243 - rs10860857 - rs4764695 - rs10860860 - rs2946831 | C-C-C-T-A C-C-C-T-A | IGF1 | Haplotype analysis:l...... Haplotype analysis:likelihood ratio test:global empirical P-value = 0.0006 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Kim, S. H.,2011 | rs10995315 - rs2297488 - rs2297489 - rs224278 | A-A-G-C A-A-G-C | EGR2 | Haplotype analysis:O...... Haplotype analysis:OR=1.543, X<sup>2</sup>=6.807, P-value = 0.0091 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Kim, S. H.,2011 | rs10995315 - rs2297488 - rs2297489 - rs224278 | G-G-C-C G-G-C-C | EGR2 | Haplotype analysis:O...... Haplotype analysis:OR=0.868, X<sup>2</sup>=1.171, P-value = 0.2792 More... | No significant asso...... No significant association was found . More... | Negative |
| Kim, S. H.,2011 | rs10995315 - rs2297488 - rs2297489 - rs224278 | G-G-C-T G-G-C-T | EGR2 | Haplotype analysis:O...... Haplotype analysis:OR=0.84, X<sup>2</sup>=2.29, P-value = 0.1302 More... | No significant asso...... No significant association was found . More... | Negative |
| Thomson, P. A., 2007 | rs10954811 - rs1503491 - rs553950 - rs327329 | NRG1 | P-value = 0.0018 for...... P-value = 0.0018 for SZ and BP combined More... | Positive | ||
| Thomson, P. A., 2007 | rs10954811 - rs1503491 - rs553950 | NRG1 | P-value = 0.0078 for...... P-value = 0.0078 for SZ and BP combined More... | Positive | ||
| Sjoholm, L. K.,2010 | rs10838524 - rs7123390 - rs10838527 - rs3824872 | A-G-A-A A-G-A-A | CRY2 | Haplotype associatio...... Haplotype association analysis:Logistic regression P-value = 0.74, OR=0.94 More... | No significant asso...... No significant association was found . More... | Negative |
| Sjoholm, L. K.,2010 | rs10838524 - rs7123390 - rs10838527 - rs3824872 | A-G-G-A A-G-G-A | CRY2 | Haplotype associatio...... Haplotype association analysis:Logistic regression P-value = 0.048, OR=1.55 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Sjoholm, L. K.,2010 | rs10838524 - rs7123390 - rs10838527 - rs3824872 | G-A-A-C G-A-A-C | CRY2 | Haplotype associatio...... Haplotype association analysis:Logistic regression P-value = 0.49, OR=0.8 More... | No significant asso...... No significant association was found . More... | Negative |
| Sjoholm, L. K.,2010 | rs10838524 - rs7123390 - rs10838527 - rs3824872 | G-G-A-C G-G-A-C | CRY2 | Haplotype associatio...... Haplotype association analysis:Logistic regression P-value = 0.024, OR=0.75 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Sjoholm, L. K.,2010 | rs10838524 - rs7123390 - rs10838527 - rs3824872 | A-A-A-C A-A-A-C | CRY2 | Haplotype associatio...... Haplotype association analysis:Logistic regression P-value = 0.043, OR=1.34 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Glaser, B.,2005(a) | rs10778502 - ss24735177 - D12S2072 | RFX4 | Haplotypic associati...... Haplotypic association:global P-value = 0.04 More... | Significant associat...... Significant association was found in global P-value. More... | Positive | |
| Glaser, B.,2005(a) | rs10778502 - ss24735177 | RFX4 | Haplotypic associati...... Haplotypic association:for Subset I, P-value(C-Ins)=0.0002, global P-value = 0.0008; for Subset II, P-value(C-Ins)=0.572, global P-value = 0.109; for Subset I+II, P-value(C-Ins)=0.002, global P-value = 0.017 More... | Strongest evidence f...... Strongest evidence for disease association in subset I, but no replication of the signal could be observed in subset II, however, when the data from the two subsets were combined significant association with BPD remained. More... | Positive | |
| Ikeda, M., 2006 | rs1050565 - rs2020934 - SLC6A4_5HTTVNTR - rs3813034 | SLC6A4 | global P-value = 0.9...... global P-value = 0.927 More... | We found no associat...... We found no association with BP in the haplotype-wise association analysis. More... | Negative | |
| Ikeda, M., 2006 | rs1050565 - rs2020934 - SLC6A4_5HTTVNTR | SLC6A4 | global P-value = 0.8...... global P-value = 0.847 More... | We found no associat...... We found no association with BP in the haplotype-wise association analysis. More... | Negative | |
| Ikeda, M., 2006 | rs1050565 - rs2020934 | SLC6A4 | global P-value = 0.6...... global P-value = 0.675 More... | We found no associat...... We found no association with BP in the haplotype-wise association analysis. More... | Negative | |
| Ross, K. A.,2011 | rs10502407 - rs9551988 | PSPC1 | SNP interactions:P-v...... SNP interactions:P-value = 0.000055 More... | No significant asso...... No significant association was found . More... | Negative | |
| Ross, K. A.,2011 | rs10502407 - rs4850057 | SNP interactions:P-v...... SNP interactions:P-value = 0.93 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Ross, K. A.,2011 | rs10502407 - rs2122231 | SNP interactions:P-v...... SNP interactions:P-value = 0.98 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Ross, K. A.,2011 | rs10502407 - rs12227938 | SNP interactions:P-v...... SNP interactions:P-value = 0.44 More... | No significant asso...... No significant association was found . More... | Negative | ||
| Ross, K. A.,2011 | rs10502407 - rs12070036 | ZNF678 | SNP interactions:P-v...... SNP interactions:P-value = 0.0000084 More... | There is a trend for...... There is a trend for significant association. More... | Trend | |
| Ross, K. A.,2011 | rs10502407 - (SNP A-1797773) | SNP interactions:P-v...... SNP interactions:P-value = 0.0000000000039 More... | Significant associat...... Significant association was found in BPD. More... | Positive | ||
| Gonzalez, R., 2015 | rs10462028 - rs1801260 - rs3805148 - rs3736544 - rs17777927 - rs11932595 - rs4340844 - rs4864542 - rs2070062 - rs13132420 | CLOCK | P-value=0.162 P-value=0.162 | No statistically sig...... No statistically significant associations were noted between CLOCK haplotypes and BD. More... | Negative | |
| Palo, O. M.,2010 | rs1024761 - rs342296 | A-G A-G | 7q22.2-7q31.33 | Haplotypic associati...... Haplotypic association:Z-score=3.538, FBAT P-value = 0.0004 More... | Significant associat...... Significant association was found. More... | Positive |
| Thomson, P. A., 2007 | rs10113797 - rs10954811 - rs1503491 - rs553950 | NRG1 | P-value = 0.0071 for...... P-value = 0.0071 for SZ and BP combined More... | Positive | ||
| Gaysina, D.,2009 | rs1011313 - rs760761 - rs2743852 | DTNBP1 | Three Marker Haploty...... Three Marker Haplotype Sliding-Window Analysis:Global P-value = 0.08, Individual P-value = 0.016 More... | No statistically sig...... No statistically significant association was found. More... | Negative | |
| Thomson, P. A., 2007 | rs10095694 - rs2919390 - rs6988339 - rs3757930 | NRG1 | P-value = 0.0114 for...... P-value = 0.0114 for BP, P-value = 0.0003 for SCZ and BP More... | Positive | ||
| Thomson, P. A., 2007 | rs10095694 - rs2919390 - rs6988339 | NRG1 | P-value = 0.0099 for...... P-value = 0.0099 for BP, P-value = 0.0002 for SCZ and BP More... | Positive | ||
| Thomson, P. A., 2007 | rs10095694 - rs2919390 | NRG1 | P-value = 0.0184 for...... P-value = 0.0184 for BP, P-value = 0.0016 for SCZ and BP More... | Positive | ||
| Gallitano, A. L.,2012 | rs10095121 - rs10104039 | C-C C-C | EGR3 | Family-Based Haploty...... Family-Based Haplotype Test:chi square=0.75, P-value = 0.387 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Gallitano, A. L.,2012 | rs10095121 - rs10104039 | C-T C-T | EGR3 | Family-Based Haploty...... Family-Based Haplotype Test:chi square=6.06, P-value = 0.014 More... | Significant associat...... Significant association was observed in BPI. More... | Positive |
| Gallitano, A. L.,2012 | rs10095121 - rs10104039 | T-C T-C | EGR3 | Family-Based Haploty...... Family-Based Haplotype Test:chi square=4.95, P-value = 0.026 More... | Significant associat...... Significant association was observed in BPI. More... | Positive |
| Gallitano, A. L.,2012 | rs10095121 - rs10104039 | T-T T-T | EGR3 | Family-Based Haploty...... Family-Based Haplotype Test:chi square=0, P-value = 0.966 More... | No significant assoc...... No significant association was observed in BD. More... | Negative |
| Harvey, M., 2007 | rs1007023 - rs4290270 | T-T T-T | TPH2 | nominal P-value = 0....... nominal P-value = 0.0038, Bonferroni corrected P-value = 0.023 under a recessive model More... | showed a significant...... showed a significant excess transmission of the more frequent haplotype, and demonstrated a stronger association between the major allele and BP status More... | Positive |
| Moskvina, V.,2011 | rs1006737 - rs1391466 | CACNA1C | Corresponding intera...... Corresponding interaction p-values in the GAIN data is 0.446011 More... | No significant asso...... No significant association was found in interaction analysis. More... | Negative | |
| Moskvina, V.,2011 | rs1006737 - rs10090710 | CACNA1C | Corresponding intera...... Corresponding interaction p-values in the GAIN data is 0.42207 More... | No significant asso...... No significant association was found in interaction analysis. More... | Negative | |
| Palo, O. M.,2010 | rs1004604 - rs987187 | A-G A-G | 9p22.2-9q21.13 | Haplotypic associati...... Haplotypic association:Z-score=-2.101, FBAT P-value = 0.035 More... | Significant associat...... Significant association was found. More... | Positive |
| Zhao, T.,2009 | rs10008257 - rs2433320 - rs2433322 - rs2438146 | A-A-G-T A-A-G-T | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.21(after Bonferroni correction), Individual P-value = 0.05, OR (95% CI)=1.8(0.99-3.29) More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Zhao, T.,2009 | rs10008257 - rs2433320 - rs2433322 | A-A-G A-A-G | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.045(after Bonferroni correction), Individual P-value = 0.031, OR (95% CI)=1.92(1.05-3.50) More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhao, T.,2009 | rs10008257 - rs2433320 - rs2433322 | G-G-A G-G-A | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.045(after Bonferroni correction), Individual P-value = 0.035, OR (95% CI)=0.81(0.67-0.99) More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Zhao, T.,2009 | rs10008257 - rs2433320 - rs2433322 | G-G-G G-G-G | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.045(after Bonferroni correction), Individual P-value < 0.001, Individual P-value = 0.029(after Bonferroni correction), OR (95% CI)=4.4(1.76-11.04) More... | Significant associat...... Significant association was found in global P-value and individual P-value. More... | Positive |
| Squassina, A.,2008 | rs10008257 - rs2433320 - rs2433322 | PDLIM5 | Global P-value = 0.0...... Global P-value = 0.033 More... | Haplotype analysis s...... Haplotype analysis showed slight statistical association for the three SNP haplotypes. Not significant after correction for multiple comparisons. More... | Positive | |
| Squassina, A.,2008 | rs10008257 - rs2433320 - rs2433322 | A-A-G A-A-G | PDLIM5 | X<sup>2</su...... X<sup>2</sup>=3.98; P-value = 0.047 More... | The most common hapl...... The most common haplotype A-A-G was more highly represented in the control group. More... | Negative |
| Squassina, A.,2008 | rs10008257 - rs2433320 - rs2433322 | A-G-A A-G-A | PDLIM5 | X<sup>2</su...... X<sup>2</sup>=0.39; P-value = 0.54 More... | Negative | |
| Squassina, A.,2008 | rs10008257 - rs2433320 - rs2433322 | G-A-G G-A-G | PDLIM5 | X<sup>2</su...... X<sup>2</sup>=5.94; P-value = 0.013 More... | Not significant afte...... Not significant after correction for multiple comparisons. The rare haplotype G-A-G was more frequent in the BD group. More... | Positive |
| Squassina, A.,2008 | rs10008257 - rs2433320 - rs2433322 | G-G-A G-G-A | PDLIM5 | X<sup>2</su...... X<sup>2</sup>=0.34; P-value = 0.56 More... | Negative | |
| Zhao, T.,2009 | rs10008257 - rs2433320 | PDLIM5 | Haplotypic associati...... Haplotypic association:Global P-value = 0.58 More... | No significant asso...... No significant association was found . More... | Negative | |
| Shi, J., 2008 (c) | rs10008257 - rs2433320 | GA GA | PDLIM5 | Association analysis...... Association analysis showed TDT P-value = 0.045. Meta-analysis showed Z test P-value = 0.674, Z=0.458 More... | A rare haplotype con...... A rare haplotype consisted of rs10008257 and rs2433320 had nominal association, which failed to survive correction for multiple tests. More... | Positive |
| Shi, J., 2008 (c) | rs10008257 - rs2433320 | GG GG | PDLIM5 | Association analysis...... Association analysis showed TDT P-value = 0.069. Meta-analysis showed Z test P-value = 0.417, Z=0.812 More... | Borderline associati...... Borderline association signals are also seen at the common haplotype GG in individual haplotype association analysis and in a global analysis More... | Negative |
| Shi, J., 2008 (c) | rs10008257 - rs2433320 | AG AG | PDLIM5 | Association analysis...... Association analysis showed TDT P-value = 0.16. Meta-analysis showed Z test P-value = 0.340, Z=0.955 More... | Negative | |
| Shi, J., 2008 (c) | rs10008257 - rs2433320 | AA AA | PDLIM5 | Association analysis...... Association analysis showed TDT P-value = 0.77. Meta-analysis showed Z test P-value = 0.168, Z=1.379 More... | Negative | |
| Squassina, A.,2008 | rs10008257 - rs2433320 | PDLIM5 | Global P-value = 0.0...... Global P-value = 0.025 More... | We found weak associ...... We found weak association for haplotypes of SNP1-SNP2. Not significant after correction for multiple comparisons. More... | Positive | |
| Squassina, A.,2008 | rs10008257 - rs2433320 | A-A A-A | PDLIM5 | X<sup>2</su...... X<sup>2</sup>=3.96; P-value = 0.047 More... | Not significant afte...... Not significant after correction for multiple comparisons. More... | Negative |
| Squassina, A.,2008 | rs10008257 - rs2433320 | A-G A-G | PDLIM5 | X<sup>2</su...... X<sup>2</sup>=0.49; P-value = 0.48 More... | Negative | |
| Squassina, A.,2008 | rs10008257 - rs2433320 | G-A G-A | PDLIM5 | X<sup>2</su...... X<sup>2</sup>=6.84; P-value = 0.009; corrected P-value = 0.040 after permutation test (10 000 permutations). More... | The most significant...... The most significant P value was obtained for the rare haplotype G-A of SNPs 1 and 2. More... | Positive |
| Squassina, A.,2008 | rs10008257 - rs2433320 | G-G G-G | PDLIM5 | X<sup>2</su...... X<sup>2</sup>=0.34; P-value = 0.56 More... | Negative | |
| Palo, O. M., 2007 | rs1000731 - rs821616 - rs1411771 | C-T-T C-T-T | DISC1 | Individual P-value =...... Individual P-value = 0.009 in all, P-value = 0.045 in males, P-value = 0.135 in females; global P-value = 0.051 in all, P-value = 0.345 in males, P-value = 0.295 in females, with bipolar spectrum disorder More... | Positive | |
| Palo, O. M., 2007 | rs1000731 - rs821616 | C-T C-T | DISC1 | Individual P-value =...... Individual P-value = 0.043 in all, P-value = 0.157 in males, P-value = 0.237 in females; global P-value = 0.025 in all, P-value = 0.208 in males, P-value = 0.218 in females, with bipolar spectrum disorder More... | Positive | |
| Schosser, A., 2010 | rs1000731 - rs7546310 - rs821597 | ACC ACC | DISC1 | Individual P-value =...... Individual P-value = 0.02, global P-value = 0.11 More... | Positive | |
| Schosser, A., 2010 | rs1000731 - rs7546310 | AC AC | DISC1 | Individual P-value =...... Individual P-value = 0.004, global P-value = 0.02 More... | showed global haplot...... showed global haplotype associations. Individual haplotype analyses showed that the A-C haplotypes of these two-marker combinations were under-represented in BD. More... | Positive |
| Dmitrzak-Weglarz, M. P., 2014 | rs534654' target=_blank>rs534654 - rs534654' target=_blank>rs534654 - rs3805148 | G-A-C G-A-C | CLOCK | BD II: Case frequenc...... BD II: Case frequency=0.336, control frequency=0.369; Chi square=0.941, P-value=0.332 More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Dmitrzak-Weglarz, M. P., 2014 | rs534654' target=_blank>rs534654 - rs534654' target=_blank>rs534654 - rs3805148 | G-G-A G-G-A | CLOCK | BD II: Case frequenc...... BD II: Case frequency=0.396, control frequency=0.308; Chi square=7.225, P-value=0.007 More... | Significant associat...... Significant association between this block and BD was observed. More... | Positive |
| Dmitrzak-Weglarz, M. P., 2014 | rs534654' target=_blank>rs534654 - rs534654' target=_blank>rs534654 - rs3805148 | G-A-A G-A-A | CLOCK | BD II: Case frequenc...... BD II: Case frequency=0.156, control frequency=0.169; Chi square=0.269, P-value=0.604 More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Dmitrzak-Weglarz, M. P., 2014 | rs534654' target=_blank>rs534654 - rs534654' target=_blank>rs534654 - rs3805148 | A-A-A A-A-A | CLOCK | BD II: Case frequenc...... BD II: Case frequency=0.112, control frequency=0.154; Chi square=2.819, P-value=0.093 More... | No significant assoc...... No significant association between this block and BD was observed. More... | Negative |
| Van Den Bogaert, A., 2006 (a) | rs4131348' target=_blank>rs4131348 - rs4131348' target=_blank>rs4131348 | C-T C-T | TPH2 | global P-value = 0.0...... global P-value = 0.004 More... | A protective BP diso...... A protective BP disorder association was also observed for hapblock 1 because of a decrease of 7.3% of the C allele of rs4131348. More... | Positive |
| Alaerts, M.,2009 | 5-HTTVNTR - 5-HTTLPR | SLC6A4 | Global simulated P-v...... Global simulated P-value = 0.22 More... | No statistically sig...... No statistically significant association was found. More... | Negative | |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 10-4-1 10-4-1 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.563703 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 5-7-2 5-7-2 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.37975 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 5-8-1 5-8-1 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.12099 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 5-8-2 5-8-2 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.759371 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 6-3-1 6-3-1 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.121547 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 6-3-2 6-3-2 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.54456 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 6-4-1 6-4-1 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.866486 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 6-4-2 6-4-2 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.789955 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 6-7-1 6-7-1 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.060892 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 6-8-2 6-8-2 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.083265 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 7-3-1 7-3-1 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.527089 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 7-4-1 7-4-1 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.006656 More... | Significant associat...... Significant association was found in both global P-value and individual P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 7-6-1 7-6-1 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.425053 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 7-6-2 7-6-2 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.062749 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 7-7-1 7-7-1 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.394215 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Voineskos, D.,2009 | 478B14-848 - 420M9-1395 - SNP8NRG221533 | 7-7-2 7-7-2 | NRG1 | Haplotype analysis:F...... Haplotype analysis:FBAT, Global X<sup>2</sup>= 29.226, df = 16, P = 0.022456; individual P-value = 0.783901 More... | Significant associat...... Significant association was found in global P-value. More... | Positive |
| Meyer, J.,2005 | 32418760(G/A) - IVS4+1008ins(T)/del(T) | SLC12A6 | Association test for...... Association test for heterogeneity, for BD, empirical P-value = 0.0017; for all cases, empirical P-value = 0.0042 More... | Significant associat...... Significant associations were found in BPD patients and all cases. More... | Positive | |
| Meyer, J.,2005 | 32418760(G/A) - 32416574(G/A) - IVS4+1008ins(T)/del(T) | SLC12A6 | Association test for...... Association test for heterogeneity, for BD, empirical P-value = 0.0022; for all cases, empirical P-value = 0.0118 More... | Significant associat...... Significant associations were found in BPD patients and all cases. More... | Positive | |
| Meyer, J.,2005 | 32418760(G/A) - 32416574(G/A) | SLC12A6 | Association test for...... Association test for heterogeneity, for BD, empirical P-value = 0.0016; for all cases, empirical P-value = 0.0064 More... | Significant associat...... Significant associations were found in BPD patients and all cases. More... | Positive | |
| Meyer, J.,2005 | 32416574(G/A) - IVS4+1008ins(T)/del(T) | SLC12A6 | Association test for...... Association test for heterogeneity, for BD, empirical P-value = 0.0175; for all cases, empirical P-value = 0.0266 More... | Significant associat...... Significant associations were found in BPD patients and all cases. More... | Positive | |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | G-G-G-A-G-A-C-C-C-A G-G-G-A-G-A-C-C-C-A | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 0.028 More... | Significant associat...... Significant association was found in individual P-value. More... | Positive |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | G-G-T-A-G-A-C-C-C-A G-G-T-A-G-A-C-C-C-A | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 0.724, OR=0.612, 95%CI=0.14-2.59 More... | No significant asso...... No significant association was found . More... | Negative |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | G-G-T-T-G-C-C-C-T-A G-G-T-T-G-C-C-C-T-A | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 0.366, OR=1.439, 95%CI=0.70-2.96 More... | No significant asso...... No significant association was found . More... | Negative |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | G-G-T-T-G-C-C-C-T-G G-G-T-T-G-C-C-C-T-G | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 0.443, OR=2.082, 95%CI=0.38-11.49 More... | No significant asso...... No significant association was found . More... | Negative |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | T-A-G-A-G-A-C-A-T-G T-A-G-A-G-A-C-A-T-G | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 1, OR=1.031, 95%CI=0.25-4.18 More... | No significant asso...... No significant association was found . More... | Negative |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | T-A-G-A-G-A-C-C-T-G T-A-G-A-G-A-C-C-T-G | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 1, OR=1.035, 95%CI=0.59-1.80 More... | No significant asso...... No significant association was found . More... | Negative |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | T-A-G-T-A-A-C-A-C-A T-A-G-T-A-A-C-A-C-A | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 0.105, OR=0.25, 95%CI=0.05-1.19 More... | No significant asso...... No significant association was found . More... | Negative |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | T-A-G-T-A-A-C-C-T-G T-A-G-T-A-A-C-C-T-G | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 0.058 More... | No significant asso...... No significant association was found . More... | Negative |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | T-A-G-T-A-A-G-A-C-A T-A-G-T-A-A-G-A-C-A | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 0.755, OR=0.919, 95%CI=0.61-1.38 More... | No significant asso...... No significant association was found . More... | Negative |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | T-A-G-T-A-A-G-A-T-A T-A-G-T-A-A-G-A-T-A | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 0.278, OR=2.615, 95%CI=0.50-13.64 More... | No significant asso...... No significant association was found . More... | Negative |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | T-A-G-T-G-A-C-C-T-G T-A-G-T-G-A-C-C-T-G | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 0.443, OR=2.081, 95%CI=0.38-11.49 More... | No significant asso...... No significant association was found . More... | Negative |
| Lai, T. J.,2005 | (TPH1_5'flanking_T-1721G) - (TPH1_5'flanking_A-1067G) - (TPH1_5'flanking_G-347T) - (TPH1_Intron1_T3804A) - (TPH1_Intron2_G7465A) - (TPH1_Intron3_A12517C) - (TPH1_Intron6_C18626G) - (TPH1_Intron7_A20004C) - (TPH1_3'UTR_C27224T) - (TPH1_3'UTR_A27237G) | T-A-G-T-G-C-G-A-C-A T-A-G-T-G-C-G-A-C-A | TPH1 | Fisher's Exact Test:...... Fisher's Exact Test:global P-value = 0.082, individual P-value = 0.498, OR=1.735, 95%CI=0.41-7.36 More... | No significant asso...... No significant association was found . More... | Negative |
| Mynett-Johnson, L.,2000 | (SLC6A4_VNTR) - (SLC6A4_3'UTR_G/T) | SLC6A4 | ETDT Analysis of Mul...... ETDT Analysis of Multimarker Haplotypes:Independent Trios, chi square=6.01, df 4, P-value = 0.217 ; All Trios, chi square=9.82, df 4, P-value = 0.050 More... | No significant assoc...... No significant association was found . More... | Negative | |
| Chowdari, K. V.,2002 | (RGS4_SNP1) - (RGS4_SNP4) - (RGS4_SNP7) - (RGS4_SNP18) | RGS4 | Estimated haplotype ...... Estimated haplotype frequencies among cases and unrelated controls:P<0.0002 More... | Significant associat...... Significant association was found in BD-I. More... | Positive | |
| Austin, J.,2000 | (NTS_3A>G) - (NTS_166C>G) | NTS | Haplotypic associati...... Haplotypic association:X<sup>2</sup> =1.96; df=3; P-value = 0.58 More... | No significant asso...... No significant association was found . More... | Negative | |
| Washizuka, S.,2003 | (NDUFV2_86C>T) - (NDUFV2_-796C>G) - (NDUFV2_-602G>A) - (NDUFV2_-233T>C) | NDUFV2 | Haplotype analysis:M...... Haplotype analysis:Monte Carlo method:P-value = 0.0001(total BPD), 0.001(BPD-I), 0.124(BPD-II), chi-square test P-value = 0.001(total BPD), 0.004(BPD-I), 0.030(BPD-II). More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Kato, T.,2001 | (mtDNA_C5178A) - (mtDNA_A10398G) | C-A C-A | mtDNA | Haplotype analysis:c...... Haplotype analysis:chi sauqre test, df=3, chi square=17.9, P<0.001 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Ohtsuki, T.,2002 | (HTR4_SVRSNP1) - (HTR4_SVRSNP4) | C-A C-A | HTR4 | Haplotype analysis:T...... Haplotype analysis:Transmission disequilibrium test:T/NT=49/27, chi square=6.4, P-value = 0.01; Model I:T/NT=54/30, chi square=6.9, P-value = 0.009; Model II:T/NT=61/37, chi square=4.1, P-value = 0.04; Model III:T/NT=69/45, chi square=3.1, P-value = 0.08 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Ohtsuki, T.,2002 | (HTR4_SVRSNP1) - (HTR4_SVRSNP4) | C-G C-G | HTR4 | Haplotype analysis:T...... Haplotype analysis:Transmission disequilibrium test:T/NT=8/13, chi square=1.2, P-value = 0.28; Model I:T/NT=8/15, chi square=2.1, P-value = 0.14; Model II:T/NT=11/18, chi square=1.3, P-value = 0.25; Model III:T/NT=12/21, chi square=2.1, P-value = 0.14 More... | No significant asso...... No significant association was found . More... | Negative |
| Ohtsuki, T.,2002 | (HTR4_SVRSNP1) - (HTR4_SVRSNP4) | T-G T-G | HTR4 | Haplotype analysis:T...... Haplotype analysis:Transmission disequilibrium test:T/NT=24/41, chi square=4.4, P-value = 0.03; Model I:T/NT=27/44, chi square=4.1, P-value = 0.04; Model II:T/NT=33/49, chi square=2.2, P-value = 0.14; Model III:T/NT=41/55, chi square=1.1, P-value = 0.3 More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Etain, B.,2004 | (HTR2A_-1438G/A) - (HTR2A_His452Tyr) | HTR2A | Haplotype analysis:P...... Haplotype analysis:P-value = 0.43 More... | No significant assoc...... No significant association was observed in BD. More... | Negative | |
| Mohammadynejad, P.,2011 | (GSTM1_positive/null) - (GSTT1_positive/null) | (GSTM1_null)-(GSTT1_...... (GSTM1_null)-(GSTT1_null) More... | GSTM1 GSTT1 | For early onset BPD,...... For early onset BPD, X<sup>2</sup> test:genotype P-value = 0.331.For late onset BPD, X<sup>2</sup> test:genotype P-value = 0.336 More... | No significant asso...... No significant association was found . More... | Negative |
| Mohammadynejad, P.,2011 | (GSTM1_positive/null) - (GSTT1_positive/null) | (GSTM1_null)-(GSTT1_...... (GSTM1_null)-(GSTT1_positive) More... | GSTM1 GSTT1 | For early onset BPD,...... For early onset BPD, X<sup>2</sup> test:genotype P-value = 0.137.For late onset BPD, X<sup>2</sup> test:genotype P-value = 0.755 More... | No significant asso...... No significant association was found . More... | Negative |
| Mohammadynejad, P.,2011 | (GSTM1_positive/null) - (GSTT1_positive/null) | (GSTM1_positive)-(GS...... (GSTM1_positive)-(GSTT1_null) More... | GSTM1 GSTT1 | For early onset BPD,...... For early onset BPD, X<sup>2</sup> test:genotype P-value = 0.032.For late onset BPD, X<sup>2</sup> test:genotype P-value = 0.639 More... | Significant associat...... Significant association was found in early-onset BD. More... | Positive |
| Barrett, T. B.,2003 | (GRK3_P-1) - (GRK3_P-5) | ADRBK2 | Haplotype analysis:G...... Haplotype analysis:Global chisquared test, 3 df, chi square=10, P-value = 0.019 on all triads combined. More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Mundo, E.,2003 | (GRIN1_1001G/C) - (GRIN1_19700A/G) - (GRIN1_6608A/G) | GRIN1 | Haplotype analysis:T...... Haplotype analysis:TDT, global X<sup>2</sup>, with four degrees of freedom, was 14.12, corresponding to a P-value = 0.007 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Thomson, P. A.,2005(b) | (GPR50_502-505) - rs13440581 | GPR50 | Haplotypic associati...... Haplotypic association:, for BPAD, P-value = 0.039(all), 0.91(female), for BPADtBPspec, P-value = 0.00023(female) More... | Association was obse...... Association was observed in BPAD and BPAD+Bpspec(female). More... | Positive | |
| Jones, I.,2000 | (ESR1_XbaI polymorphism) - (ESR1_PvuII polymorphism) | ESR1 | Haplotype analysis:C...... Haplotype analysis:Clump X<sup>2</sup>=3.92, P-value = 0.26 More... | No significant assoc...... No significant association was observed in BD. More... | Negative | |
| Lin, C. I.,2010 | (DRD3_Ser9Gly) - (5-HTTLPR) | DRD3 SLC6A4 | multiple regression:...... multiple regression:BP-I vs. control group, OR(95%CI)=0.144(0.014-1.479), P-value = 0.103; BP-II vs. control group, OR(95%CI)=1.231(0.173-8.767), P-value = 0.835; BP-I vs. BP-II, OR(95%CI)=0.154(0.023-1.032), P-value = 0.054 More... | No significant asso...... No significant association was found . More... | Negative | |
| Ni, X.,2002 | (DRD1_-800T/C) - (DRD1_-48A/G) - (DRD1_1403T/C) | DRD1 | Haplotype analysis:G...... Haplotype analysis:Global X<sup>2</sup>=18.534, df=7, P-value = 0.0098; for the common haplotypes (those with frequencies 3%), X<sup>2</sup>=16.068, df=3, P-value = 0.0011. More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Greenwood, T. A.,2001 | (DAT_P+214A/G) - (DAT_I1+1036C/A) - (DAT_I1+1736G/A) - (DAT_I1+1860A/G) - (DAT_I2+48G/A) - (DAT_I6+96G/C) | SLC6A3 | Haplotype analysis:T...... Haplotype analysis:TDT, allele P-value = 0.29, empirical P-value = 0.455; genotype P-value = 0.095, empirical P-value = 0.309 More... | No significant asso...... No significant association was found . More... | Negative | |
| Greenwood, T. A.,2001 | (DAT_I9+102G/T) - (DAT_I9-21G/A) - (DAT_I10+117G/A) - (DAT_E15+274G/C) - (DAT_E15+352G/A) - (DAT_E15+1812T/C) | SLC6A3 | Haplotype analysis:T...... Haplotype analysis:TDT, genotype P-value = 0.006, empirical P-value = 0.023 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Greenwood, T. A.,2001 | (DAT_I9+102G/T) - (DAT_I9-21G/A) - (DAT_I10+117G/A) | SLC6A3 | Haplotype analysis:T...... Haplotype analysis:TDT, allele P-value = 0.073, empirical P-value = 0.108; genotype P-value = 0.01, empirical P-value = 0.024 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Greenwood, T. A.,2001 | (DAT_I1+1860A/G) - (DAT_I1+1861G/A) - (DAT_I2+48G/A) | SLC6A3 | Haplotype analysis:T...... Haplotype analysis:TDT, allele P-value = 0.403, empirical P-value = 0.472; genotype P-value = 0.246, empirical P-value = 0.355 More... | No significant asso...... No significant association was found . More... | Negative | |
| Greenwood, T. A.,2001 | (DAT_I1+1036C/A) - (DAT_I1+1736G/A) | SLC6A3 | Haplotype analysis:T...... Haplotype analysis:TDT, allele P-value = 0.686, empirical P-value = 0.745; genotype P-value = 0.686, empirical P-value = 0.745 More... | No significant asso...... No significant association was found . More... | Negative | |
| Greenwood, T. A.,2001 | (DAT_E9+59A/G) - (DAT_I9+102G/T) - (DAT_I9-21G/A) - (DAT_E15+274G/C) - (DAT_E15+1812T/C) | SLC6A3 | Haplotype analysis:T...... Haplotype analysis:TDT, allele P-value = 0.0009, empirical P-value = 0.001; genotype P-value = 0.0002, empirical P-value = 0.0004 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Greenwood, T. A.,2001 | (DAT_E9+59A/G) - (DAT_I9+102G/T) | SLC6A3 | Haplotype analysis:T...... Haplotype analysis:TDT, allele P-value = 0.321, empirical P-value = 0.324; genotype P-value = 0.023, empirical P-value = 0.044 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Greenwood, T. A.,2001 | (DAT_E15+274G/C) - (DAT_E15+352G/A) - (DAT_E15+1812T/C) | SLC6A3 | Haplotype analysis:T...... Haplotype analysis:TDT, allele P-value = 0.094, empirical P-value = 0.09; genotype P-value = 0.031, empirical P-value = 0.036 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Ancin, I.,2011(a) | (CHRNA7_-86C/T) - rs883473 - rs6494223 - rs904952 | C-C-C-C C-C-C-C | CHRNA7 | Haplotype analysis, ...... Haplotype analysis, in subjects who carried out CPT-DS, P-value = 0.08 More... | No significant asso...... No significant association was found . More... | Negative |
| Ancin, I.,2011(a) | (CHRNA7_-86C/T) - rs883473 - rs6494223 - rs904952 | C-C-C-T C-C-C-T | CHRNA7 | Haplotype analysis, ...... Haplotype analysis, in subjects who carried out CPT-DS, P-value = 0.77 More... | No significant asso...... No significant association was found . More... | Negative |
| Ancin, I.,2011(a) | (CHRNA7_-86C/T) - rs883473 - rs6494223 - rs904952 | C-C-T-C C-C-T-C | CHRNA7 | Haplotype analysis, ...... Haplotype analysis, in subjects who carried out CPT-DS, P-value = 0.18 More... | No significant asso...... No significant association was found . More... | Negative |
| Ancin, I.,2011(a) | (CHRNA7_-86C/T) - rs883473 - rs6494223 - rs904952 | C-C-T-T C-C-T-T | CHRNA7 | Haplotype analysis, ...... Haplotype analysis, in subjects who carried out CPT-DS, P-value = 0.22 More... | No significant asso...... No significant association was found . More... | Negative |
| Ancin, I.,2011(a) | (CHRNA7_-86C/T) - rs883473 - rs6494223 - rs904952 | C-T-C-C C-T-C-C | CHRNA7 | Haplotype analysis, ...... Haplotype analysis, in subjects who carried out CPT-DS, P-value = 0.89 More... | No significant asso...... No significant association was found . More... | Negative |
| Ancin, I.,2011(a) | (CHRNA7_-86C/T) - rs883473 - rs6494223 - rs904952 | C-T-C-T C-T-C-T | CHRNA7 | Haplotype analysis, ...... Haplotype analysis, in subjects who carried out CPT-DS, P-value = 0.37 More... | No significant asso...... No significant association was found . More... | Negative |
| Ancin, I.,2011(a) | (CHRNA7_-86C/T) - rs883473 - rs6494223 - rs904952 | C-T-T-C C-T-T-C | CHRNA7 | Haplotype analysis, ...... Haplotype analysis, in subjects who carried out CPT-DS, P-value = 0.36 More... | No significant asso...... No significant association was found . More... | Negative |
| Ancin, I.,2011(a) | (CHRNA7_-86C/T) - rs883473 - rs6494223 - rs904952 | C-T-T-T C-T-T-T | CHRNA7 | Haplotype analysis, ...... Haplotype analysis, in subjects who carried out CPT-DS, P-value = 0.94 More... | No significant asso...... No significant association was found . More... | Negative |
| Ancin, I.,2011(a) | (CHRNA7_-86C/T) - rs883473 - rs6494223 - rs904952 | T-C-C-C T-C-C-C | CHRNA7 | Haplotype analysis, ...... Haplotype analysis, in subjects who carried out CPT-DS, P-value = 0.2 More... | No significant asso...... No significant association was found . More... | Negative |
| Ancin, I.,2011(a) | (CHRNA7_-86C/T) - rs883473 - rs6494223 - rs904952 | T-C-C-T T-C-C-T | CHRNA7 | Haplotype analysis, ...... Haplotype analysis, in subjects who carried out CPT-DS, P-value = 0.3 More... | No significant asso...... No significant association was found . More... | Negative |
| Kurumaji, A.,2001 | (BZRP_exon_Ala147Thr) - ( BZRP_exon_His162Arg) | TSPO | Haplotypic associati...... Haplotypic association:P-value = 0.120 More... | No significant asso...... No significant association was found . More... | Negative | |
| Toyota, T.,2003 | (AKT1_1251C>T) - ( AKT1_IVS14+32G>A) - ( AKT1_IVS14+66C>G) - ( AKT1_IVS14+93C>T) - ( AKT1_IVS14+98A>G) - ( AKT1_IVS14+105_106ins_CTCAC or CTCAG) | C-G-C-C-G-insCTCAG C-G-C-C-G-insCTCAG | AKT1 | PDT analysis of hapl...... PDT analysis of haplotype transmission in the bipolar pedigrees under the affection status model I (II):Parent-to-offspring, T/NT=52(73)/60(83); Transmission in disordant sibs, affected/non-affected=130(139)/198(179); Z score=-1.5(-1.3), P-value = 0.136(0.2) More... | No significant asso...... No significant association was found . More... | Negative |
| Toyota, T.,2003 | (AKT1_1251C>T) - ( AKT1_IVS14+32G>A) - ( AKT1_IVS14+66C>G) - ( AKT1_IVS14+93C>T) - ( AKT1_IVS14+98A>G) | C-G-C-C-A C-G-C-C-A | AKT1 | PDT analysis of hapl...... PDT analysis of haplotype transmission in the bipolar pedigrees under the affection status model I (II):Parent-to-offspring, T/NT=21(27)/13(20); Transmission in disordant sibs, affected/non-affected=49(52)/58(51); Z score=2.1(2.1), P-value = 0.039(0.038) More... | Significant associat...... Significant association was found in BD. More... | Positive |
| Toyota, T.,2003 | (AKT1_1251C>T) - ( AKT1_IVS14+32G>A) - ( AKT1_IVS14+66C>G) - ( AKT1_IVS14+93C>T) - ( AKT1_IVS14+98A>G) | C-G-G-C-A C-G-G-C-A | AKT1 | PDT analysis of hapl...... PDT analysis of haplotype transmission in the bipolar pedigrees under the affection status model I (II):Parent-to-offspring, T/NT=6(12)/5(8); Transmission in disordant sibs, affected/non-affected=8(14)/16(13); Z score=-0.9(0.6), P-value = 0.345(0.555) More... | No significant asso...... No significant association was found . More... | Negative |
| Toyota, T.,2003 | (AKT1_1251C>T) - ( AKT1_IVS14+32G>A) - ( AKT1_IVS14+66C>G) - ( AKT1_IVS14+93C>T) - ( AKT1_IVS+95-98delCTCA) | C-G-C-C-del C-G-C-C-del | AKT1 | PDT analysis of hapl...... PDT analysis of haplotype transmission in the bipolar pedigrees under the affection status model I (II):Parent-to-offspring, T/NT=1(2)/2(3); Transmission in disordant sibs, affected/non-affected=7(7)/12(9); Z score=-0.4(-0.9), P-value = 0.654(0.361) More... | No significant asso...... No significant association was found . More... | Negative |
| Toyota, T.,2002 | (ADCY9_2316A>G) - ( ADCY9_(TTTA)n) | ADCY9 | Haplotype analysis:X...... Haplotype analysis:X<sup>2</sup> test, P-value = 0.188 More... | No significant asso...... No significant association was found . More... | Negative | |
| Mynett-Johnson, L.,2000 | (5-HTTLPR) - ( SLC6A4_VNTR) - ( SLC6A4_3'UTR_G/T) | SLC6A4 | ETDT Analysis of Mul...... ETDT Analysis of Multimarker Haplotypes:Independent Trios, chi square=17.65, df 8, P-value = 0.04; All Trios, chi square=16.60, df 8, P-value = 0.049 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Mynett-Johnson, L.,2000 | (5-HTTLPR) - ( SLC6A4_VNTR) | SLC6A4 | ETDT Analysis of Mul...... ETDT Analysis of Multimarker Haplotypes:Independent Trios, chi square=8.89, df 4, P-value = 0.076 ; All Trios, chi square=6.34, df 4, P-value = 0.186 More... | No significant asso...... No significant association was found . More... | Negative | |
| Mynett-Johnson, L.,2000 | (5-HTTLPR) - ( SLC6A4_3'UTR_G/T) | SLC6A4 | ETDT Analysis of Mul...... ETDT Analysis of Multimarker Haplotypes:Independent Trios, chi square=12.91, df 3, P-value = 0.005; All Trios, chi square=12.14, df 3, P-value = 0.005 More... | Significant associat...... Significant association was found in BD. More... | Positive | |
| Ni, X.,2002 | (5-HT2A_102T/C) - ( 5-HT2A_His452Tyr) | (5-HT2A_102C)-(5-HT2...... (5-HT2A_102C)-(5-HT2A_452His) More... | HTR2A | Haplotypic associati...... Haplotypic association:TDT: Chi-square(1df)=3.83 P-value > 0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Ni, X.,2002 | (5-HT2A_102T/C) - ( 5-HT2A_His452Tyr) | (5-HT2A_102C)-(5-HT2...... (5-HT2A_102C)-(5-HT2A_452Tyr) More... | HTR2A | Haplotypic associati...... Haplotypic association:TDT: Chi-square(1df)=0.465 P-value > 0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Ni, X.,2002 | (5-HT2A_102T/C) - ( 5-HT2A_His452Tyr) | (5-HT2A_102T)-(5-HT2...... (5-HT2A_102T)-(5-HT2A_452His) More... | HTR2A | Haplotypic associati...... Haplotypic association:TDT: Chi-square(1df)=2.106 P-value > 0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Ni, X.,2002 | (5-HT2A_102T/C) - ( 5-HT2A_His452Tyr) | (5-HT2A_102T)-(5-HT2...... (5-HT2A_102T)-(5-HT2A_452Tyr) More... | HTR2A | Haplotypic associati...... Haplotypic association:TDT: Chi-square(1df)=0.529 P-value > 0.05 More... | No significant asso...... No significant association was found . More... | Negative |
| Ozdemircan, A., 2015 | COX-2-765G: 1195A COX-2-765G: 1195A | COX-2 | P-value=0.0099 P-value=0.0099 | Haplotype analysis c...... Haplotype analysis confirmed the association of gene variants with BD-I and revealed that the frequencies of COX-2-765G: 1195A haplotype frequencies were significantly higher in patients compared with those of controls. More... | Positive | |
| Ozdemircan, A., 2015 | COX-2-765C: 1195A COX-2-765C: 1195A | COX-2 | P-value=0.6456 P-value=0.6456 | Negative | ||
| Ozdemircan, A., 2015 | COX-2-765G: 1195G COX-2-765G: 1195G | COX-2 | P-value=0.0018 P-value=0.0018 | COX-2-765G: 1195G an...... COX-2-765G: 1195G and COX-2-765C: 1195G haplotype frequencies were significantly higher in controls compared with those of patients. More... | Positive | |
| Ozdemircan, A., 2015 | COX-2-765C: 1195G COX-2-765C: 1195G | COX-2 | P-value=0.0371 P-value=0.0371 | COX-2-765G: 1195G an...... COX-2-765G: 1195G and COX-2-765C: 1195G haplotype frequencies were significantly higher in controls compared with those of patients. More... | Positive |