Gene Report

Basic Info
Approved Symbol DIO2
Symbol Alias TXDI2, SelY
Approved Name deiodinase, iodothyronine, type II
Name Alias thyroxine deiodinase, type II, "deiodonase-2", "deiodinase-2"
Location 14q24.2-q24.3
Position chr14:80197527-80387757, -1
External Links HGNC: 2884
Entrez Gene: 1734
Ensembl: ENSG00000211448
UCSC: uc021rxb.1
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
He, B.,2009 SNP: rs12885300, rs225014
Haplotype: rs12885300 - rs225014()
Data generated from this study supported our hypothesis that genetic variations of the DIO2 gene were associated with BPAD Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 13)

GO terms by PBA (count: 3)

GO terms by database search (count: 10)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 6)

Literature-origin SNPs (count: 2)

LD-proxies (count: 4)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr14:80197527..80387757 View in gBrowse
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