SNP Report

Basic Info

Name	rs6354 dbSNP Ensembl
Location	chr17:30222880 - 30222880(1)
Variant Alleles	G/T
Ancestral Allele	T
Minor Allele	G
Minor Allele Frequence	0.203674
Functional Annotation	5_prime_UTR_variant; intron_variant.
Consequence to Transcript	5_prime_UTR_variant(ENST00000261707, ENST00000394821); intron_variant(ENST00000401766)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Mansour, H. A.,2005	G/T		Pittsburgh BD1 sample: trends test for case-control analysis...... Pittsburgh BD1 sample: trends test for case-control analysis, P-value = 0.839; TDT T/NT=16/17; STEP-BD sample: trends test for case-control analysis, P-value = Pittsburgh BD1 sample: trends test for case-control analysis, P-value = 0.839; TDT T/NT=16/17 More...	No significant association was observed. No significant association was observed.	Negative
Sun, H. S., 2004	A/C		Fisher's exact test, allelic P-value = 1, genotypic P-value ...... Fisher's exact test, allelic P-value = 1, genotypic P-value = 0.96 More...	No association can be obtained between any of the SLC6A4 gen...... No association can be obtained between any of the SLC6A4 gene polymorphisms and BPD. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLC6A4	solute carrier family 6 (neurotransmitter transporter), member 4	17q11.2	44(18/26/0)

SNPs in LD with rs6354 (count: 4) View in gBrowse (chr17:30161773..30225755 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs11080122	intron_variant	0.939[CEU]; 0.966[TSI]; 0.863[CHD]; 0.897[JPT]
rs8071667	intron_variant	0.938[CEU]; 0.867[TSI]; 0.817[CHD]; 0.896[JPT]
rs4494608	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.817[CHD]
rs8076005	intron_variant	0.879[CEU]; 0.967[TSI]; 0.938[CHD]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)