BDgene

SNP Report

Basic Info
Name rs10506645 dbSNP Ensembl
Location chr12:71991720 - 71991720(1)
Variant Alleles C/T
Ancestral Allele T
Minor Allele T
Minor Allele Frequence 0.26857
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000333850)
No. of Studies 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Roche, S.,2009 T TDT: X2=1, P-value = 0.3173 TDT: X2=1, P-value = 0.3173 No significant association was observed No significant association was observed Negative
Campos, S. B., 2010 The allele and genotype distribution of all SNPs showed no d...... The allele and genotype distribution of all SNPs showed no differences between BD patients and controls. More... Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TPH2 tryptophan hydroxylase 2 12q15 13(10/3/0)

SNPs in LD with rs10506645 (count: 17) View in gBrowse (chr12:71948504..72014217 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 17)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)