BDgene

SNP Report

Basic Info
Name rs4713916 dbSNP Ensembl
Location chr6:35702206 - 35702206(1)
Variant Alleles A/G
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.222045
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000536438)
No. of Studies 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? YES

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Szczepankiewicz A., 2014 A/G P-value=0.614 P-value=0.614 Our main finding is no association with bipolar disorder. Our main finding is no association with bipolar disorder. Negative
Gawlik, M., 2006 A/G allelic P-value = 0.38, genotypic P-value = 0.12 allelic P-value = 0.38, genotypic P-value = 0.12 Allele and genotype frequencies of rs4713916 were not signif...... Allele and genotype frequencies of rs4713916 were not significantly different between cases and controls. More... Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
FKBP5 FK506 binding protein 5 6p21.31 5(1/4/0)

SNPs in LD with rs4713916 (count: 0) View in gBrowse (chr6:35702206..35702206 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Szczepankiewicz A., 2014 P-value=0.038 Our main finding is an association of FKBP5 polymorphisms (rs1360780, rs9470080, rs4713916, rs9296158 and rs9394309) with major depression but nor with bipolar disorder. Positive