SNP Report

Basic Info

Name	rs2304865 dbSNP Ensembl
Location	chr4:186604209 - 186604209(1)
Variant Alleles	C/G
Ancestral Allele	C
Minor Allele	G
Minor Allele Frequence	0.263179
Functional Annotation	intron_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000441802, ENST00000614102); upstream_gene_variant(ENST00000503253)
No. of Studies	3 (Positive: 2; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 3)

Reference	Allele Change	Statistical Values	Author Comments	Result Category
Yosifova, A.,2009	C/G	Allelic association: P-value = 0.38 Allelic association: P-value = 0.38	No significant association was observed No significant association was observed	Negative
Abou Jamra, R, 2008 (a)	C/G	allelic P-value = 0.03737; OR=1.36 allelic P-value = 0.03737; OR=1.36	showed association with bipolar affective disorder showed association with bipolar affective disorder	Positive
Blair, I. P., 2006		Allelic P-value = 0.007, genotypic P-value = 0.009 in Aust c...... Allelic P-value = 0.007, genotypic P-value = 0.009 in Aust case-control; Allelic P-value = 0.274, genotypic P-value = 0.542 in UK case-control for overall; Allelic P-value = 0.007, genotypic P-value = 0.006 in Aust case-control; Allelic P-value = 0.007, genotypic P-value = 0.025 in UK case-control with positive family history; Allelic P-value = 0.31, genotypic P-value = 0.528 in Aust case-control; Allelic P-value = 0.841, genotypic P-value = 0.975 in UK case-control with negative family history; Allelic P-value = 0.092, genotypic P-value = 0.176 in Aust case-control; Allelic P-value = 0.466, genotypic P-value = 0.487 in UK case-control with lifetime psychotic episode; Allelic P-value = 0.012, genotypic P-value = 0.011 in Aust case-control; Allelic P-value = 0.085, genotypic P-value = 0.079 in UK case-control with no psychotic episode; pooled P-value = 0.0002, OR=2.31 More...	The SNP provided statistically significant evidence for asso...... The SNP provided statistically significant evidence for association in the Australian case-control cohort. In the pooled data analysis, SNP rs2304865 showed significant evidence for association (P=0.0002) with a summary odds ratio (OR) of 2.31 and remained significant after applying a Bonferroni correction for multiple testing. No case-control cohort showed evidence for association among psychosis or non-psychosis subsets. More...	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CD36	CD36 molecule (thrombospondin receptor)	7q11.2	3(2/1/0)
FAT1	FAT atypical cadherin 1	4q35.2	Mapped by Literature SNP

SNPs in LD with rs2304865 (count: 0) View in gBrowse (chr4:186604209..186604209 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)