BDgene

SNP Report

Basic Info
Name rs906807 dbSNP Ensembl
Location chr18:9117869 - 9117869(1)
Variant Alleles T/C
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.221046
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant; intron_variant; missense_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant.
Polyphen Annotation: benign(ENST00000318388, ENST00000400033)
SIFT Annotation: tolerated(ENST00000318388, ENST00000400033)
Consequence to Transcript 3_prime_UTR_variant(ENST00000577703); downstream_gene_variant(ENST00000582375, ENST00000583081); intron_variant(ENST00000578850); missense_variant(ENST00000318388, ENST00000400033); NMD_transcript_variant(ENST00000577703); non_coding_transcript_exon_variant(ENST00000474350, ENST00000483511, ENST00000579126, ENST00000583375); non_coding_transcript_variant(ENST00000474350, ENST00000483511, ENST00000578850, ENST00000579126, ENST00000583375); upstream_gene_variant(ENST00000465096, ENST00000579467)
No. of Studies 3 (Positive: 1; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Yosifova, A.,2009 A/G Allelic association: P-value = 0.48 Allelic association: P-value = 0.48 No significant association was observed No significant association was observed Negative
Zhang, J.,2009 C/T C Allelic association: Odds ratio=1.071, P-value = 0.553; Geno...... Allelic association: Odds ratio=1.071, P-value = 0.553; Genotypic association: P-value = 0.255 More... No significant association was observed No significant association was observed Negative
Doyle, G. A.,2011 G/A A chi suqare test: genotype, X2=4.711, P-value = 0....... chi suqare test: genotype, X2=4.711, P-value = 0.095; allele A, X2=5.362, P-value = 0.021 More... Significant association was found in allele association. Significant association was found in allele association. Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 18p11.22 6(5/1/0)

SNPs in LD with rs906807 (count: 32) View in gBrowse (chr18:9095069..9274638 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 32)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016