Gene Report

Basic Info
Approved Symbol CHMP1B
Symbol Alias CHMP1.5, C18orf2, Vps46B
Approved Name charged multivesicular body protein 1B
Previous Name chromatin modifying protein 1B
Location 18p11.21
Position chr18:11851396-11854449, 1
External Links HGNC: 24287
Entrez Gene: 57132
Ensembl: ENSG00000255112
UCSC: uc002kqe.3
No. of Studies 2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
McNabb, L. D.,2005 SNP: rs1249624, rs1786581
Haplotype: rs1786581 - rs1249624()
Variation in the CHMP1.5 gene does not appear to be associated with bipolar disorder. Negative Comment on Study
Yosifova, A.,2009 SNP: rs1786581 No SNP of this gene had significant association with BD in our population. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 17)

GO terms by PBA (count: 2)

GO terms by database search (count: 15)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 13)

Related other genetic factors
Gene related SNPs (count: 2)

Literature-origin SNPs (count: 2)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 5)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr18:11851396..11854449 View in gBrowse
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