Gene Report

Basic Info
Approved Symbol GSTT1
Approved Name glutathione S-transferase theta 1
Location 22q11.23 alternate reference locus
Position chr22:270314-278459, -1
External Links HGNC: 4641
Entrez Gene: 2952
Ensembl: ENSG00000277656
UCSC: uc002zze.4
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Mohammadynejad, P.,2011 Haplotype: (GSTM1_positive/null) - (GSTT1_positive/null)((GSTM1_null)-(GSTT1_null)), (GSTM1_positive/null) - (GSTT1_positive/null)((GSTM1_null)-(GSTT1_positive)), (GSTM1_positive/null) - (GSTT1_positive/null)((GSTM1_positive)-(GSTT1_null))
Other variant: GSTT1_positive/null
The present finding indicated that GSTM1 and GSTT1 are candidate polymorphisms for susceptibility to BDP among adolescents. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 9)

GO terms by PBA (count: 2)

GO terms by database search (count: 7)

Gene related KEGG pathways (count: 3)

KEGG pathways by PBA (count: 2)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 2)

Gene relationship with MDD

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Region: chr22:270314..278459 View in gBrowse
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