SNP Report

Basic Info

Name	rs11633223 dbSNP Ensembl
Location	chr15:78643134 - 78643134(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.20647
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000559849, ENST00000560511); NMD_transcript_variant(ENST00000559849); non_coding_transcript_variant(ENST00000560511); upstream_gene_variant(ENST00000261751, ENST00000412074)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2007	A/G		TDT P-value = 0.67 of Allelic Association With Bipolar Disor...... TDT P-value = 0.67 of Allelic Association With Bipolar Disorder in the Combined Sample More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CHRNB4	cholinergic receptor, nicotinic, beta 4 (neuronal)	15q24	2(1/1/0)

SNPs in LD with rs11633223 (count: 2) View in gBrowse (chr15:78636604..78643134 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs11636753		intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.956[CEU]
rs11637890		intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)