SNP Report

Basic Info

Name	rs10954811 dbSNP Ensembl
Location	chr8:31728937 - 31728937(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.142372
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000518104, ENST00000519301, ENST00000520407, ENST00000523534)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Thomson, P. A., 2007			Individual P-value = 0.9292 for BP, Individual P-value = 0.8...... Individual P-value = 0.9292 for BP, Individual P-value = 0.8101 for SCZ and BP More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs10954811 (count: 52) View in gBrowse (chr8:31691740..31847587 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 52)

rs_ID	Functional Annotation	r²[population]
rs6468066	intron_variant	0.879[CEU]
rs13249835	intron_variant	0.879[CEU]
rs1995467	intron_variant	0.879[CEU]; 0.882[TSI]
rs7820923	intron_variant	0.879[CEU]; 0.882[TSI]
rs13251192	intron_variant	0.879[CEU]
rs7825505	intron_variant	0.879[CEU]
rs10104297	intron_variant	0.879[CEU]; 0.882[TSI]
rs1503488	intron_variant	0.856[TSI]
rs1503487	intron_variant	0.879[CEU]; 0.882[TSI]
rs1503497	intron_variant	0.878[CEU]; 0.849[TSI]
rs1503490	intron_variant	0.879[CEU]
rs4521723	intron_variant	0.887[CEU]
rs11775125	intron_variant	1.0[CEU]; 0.968[TSI]
rs11781163	intron_variant	0.879[CEU]; 0.91[TSI]
rs11776163	intron_variant	1.0[CEU]
rs7016384	intron_variant	1.0[CEU]
rs11993157	intron_variant	0.879[CEU]; 0.882[TSI]
rs10503891	intron_variant	0.879[CEU]
rs11775517	intron_variant	0.867[CEU]
rs7002293	intron_variant	0.933[CEU]
rs2134619	intron_variant	0.879[CEU]
rs4733275	intron_variant	0.879[CEU]; 0.882[TSI]
rs10954810	intron_variant	1.0[CEU]; 0.968[TSI]
rs11779083	intron_variant	0.826[CEU]
rs10104764	intron_variant	0.879[CEU]
rs6468067	intron_variant	0.856[TSI]
rs11784088	intron_variant	1.0[CEU]; 0.968[TSI]
rs7014206	intron_variant	0.873[CEU]
rs6993559	intron_variant	1.0[CEU]; 0.936[TSI]
rs10954813	intron_variant	0.879[CEU]
rs6468060	intron_variant	1.0[CEU]
rs6987310	intron_variant	0.879[CEU]; 0.878[TSI]
rs6468065	intron_variant	0.939[CEU]
rs1546326	intron_variant	0.879[CEU]; 0.882[TSI]
rs701955	intron_variant	0.879[CEU]
rs7821017	intron_variant	0.826[CEU]
rs7003184	intron_variant	1.0[CEU]; 0.968[TSI]
rs13282705	intron_variant	0.879[CEU]
rs7813321	intron_variant	0.879[CEU]; 0.882[TSI]
rs1393953	intron_variant	0.879[CEU]
rs4733098	intron_variant	0.879[CEU]
rs7836838	intron_variant	0.879[CEU]
rs7006674	intron_variant	0.887[CEU]
rs1393952	intron_variant	0.879[CEU]; 0.882[TSI]
rs11776643	intron_variant	1.0[CEU]; 0.936[TSI]
rs7820929	intron_variant	0.879[CEU]
rs7014729	intron_variant	0.877[CEU]
rs7817052	intron_variant	0.905[CEU]
rs1354336	intron_variant	0.879[CEU]; 0.882[TSI]
rs13279016	intron_variant	0.873[CEU]; 0.88[TSI]
rs11774988	intron_variant	0.887[CEU]
rs2345990	intron_variant	0.873[CEU]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Thomson, P. A., 2007	Individual P-value = 0.6247 for SCZ , Individual P-value = 0.8101 for SCZ and BP		Negative

Overlap with MDD from cross-disorder studies (count: 0)