Study Report

Basic Info
Citation Georgi, B., et al. (2014). "Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate." PLoS Genet 10(3): e1004229.
Disease Type Bipolar Disorder
Study Design family-based & pedigree
Study Type Genome-wide association study, Linkage study, Mutational study
Sample Size 497 individuals from a large pedigree were used for linkage analysis using microsatellite data. 388 out of them were used for genotyping using illumina Omni SNP array. 50 out of them were for whole genome sequencing, comprising 18 parent-child trios.
SNP/Region/Marker Size 11M SNPs of whole genome sequence data, 2.5M SNPs of illumina Omni SNP array, 2000 markers of microsatellite data.
Predominant Ethnicity Caucasian
Population Old Order Amish pedigree
Age Group adults : The average age of onset for BPI patients was 24.6.

Detail Info

SNPs reported by this study for BD (count: 73)

Haplotypes reported by this study for BD (count: 1)

Other variants reported by this study for BD (count: 6)

Genes reported by this study for BD (count: 63)

Regions reported by this study for BD (count: 5)