SNP Report

Basic Info
Name rs10995315 dbSNP Ensembl
Location chr10:62814811 - 62814811(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.0894569
Functional Annotation intron_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000242480, ENST00000411732, ENST00000439032, ENST00000493899, ENST00000637191, LRG_239t1); non_coding_transcript_variant(ENST00000493899)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kim, S. H.,2011 G/A For BD, chi-square tests: allele, OR=1.664, X2=9....... For BD, chi-square tests: allele, OR=1.664, X2=9.5297, P-value = 0.002, P-value(permutation)=0.0127; Fisher's exact test, genotype, X2=9.9742, P-value = 0.0068 More... Significant associations were found in both allele and genot...... Significant associations were found in both allele and genotype association. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
EGR2 early growth response 2 10q21.1 3(1/2/0)

SNPs in LD with rs10995315 (count: 4) View in gBrowse (chr10:62789094..62831852 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 4)

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Kim, S. H.,2011 For SZ, chi-square tests:allele, OR=1.116, X2=0.3138, P-value = 0.5754, P-value(permutation)=0.99;Fisher's exact test, genotype, X2=2.8926, P-value = 0.2354 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 0)