Gene Report

Basic Info
Approved Symbol PPP3CC
Symbol Alias CALNA3, PP2Bgamma
Approved Name protein phosphatase 3, catalytic subunit, gamma isozyme
Previous Name protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma), "protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform"
Name Alias calcineurin A gamma, "protein phosphatase 2B, catalytic subunit, gamma isoform"
Location 8p21.3
Position chr8:22440819-22541142, 1
External Links HGNC: 9316
Entrez Gene: 5533
Ensembl: ENSG00000120910
UCSC: uc011kzi.2
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Fallin, M. D.,2005 9 SNP typed, Median D'=0.97, Median r<sup>2</sup> =0.88, 2 LD blocks, 0.86 block coverage, all SNP or haplotype P-value > 0.05 in BP and SZ/SZA... This gene is not suggestive to BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 10)

GO terms by PBA (count: 1)

GO terms by database search (count: 9)

Gene related KEGG pathways (count: 10)

Gene related BioCarta pathways (count: 12)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 2)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 10)

Gene relationship with MDD

View in gBrowse

Region: chr8:22440819..22541142 View in gBrowse
View in gBrowse