BDgene

Gene Report

Basic Info
Approved Symbol CAMKK2
Symbol Alias CAMKK, KIAA0787, CAMKKB, MGC15254
Approved Name calcium/calmodulin-dependent protein kinase kinase 2, beta
Location 12q24.2
Position chr12:121237691-121298308, -1
External Links HGNC: 1470
Entrez Gene: 10645
Ensembl: ENSG00000110931
UCSC: uc001tzu.3
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Barden, N., 2006 SNP: rs3817190
Haplotype: rs1653625 - rs4980999 - rs3817190 - rs28360477(C-C-T-C), rs1653625 - rs4980999 - rs3817190 - rs28360477(C-C-A-C), rs1653625 - rs4980999 - rs3817190 - rs28360477(G-C-T-C), rs1653625 - rs4980999 - rs3817190 - rs28360477(C-T-T-C), rs1653625 - rs4980999 - rs3817190 - rs28360477(G-C-A-T), rs1653625 - rs4980999 - rs3817190 - rs28360477(G-C-A-C), rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190(A-A-G-G-C-T-T), rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190(A-C-A-A-C-C-A), rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190(A-C-A-A-C-C-T), rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190(A-C-A-A-C-T-T), rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190(A-C-A-A-G-C-A), rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190(A-C-A-A-G-C-T), rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190(A-C-G-A-C-C-A), rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190(A-C-G-A-C-C-T), rs1653625 - rs28360463 - rs1653622 - rs11065500 - rs11065501 - rs4980999 - rs3817190(C-C-A-A-C-C-T)
Allelic, genotypic or family-based association studies suggest the presence of two susceptibility loci, the P2RX7 and CaMKK2genes. Positive Comment on Study
McQuillin, A.,2009 SNP: rs3817190 No significant association was observed with BP. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 16)

GO terms by PBA (count: 3)

GO terms by database search (count: 13)


Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 0)


Gene related BioCarta pathways (count: 1)

BioCarta pathways by PBA (count: 0)

BioCarta pathways by database search (count: 1)


Gene related interactors from protein-protein interactions data in HPRD (count: 3)

Related other genetic factors
Gene related SNPs (count: 8)

Literature-origin SNPs (count: 3)

LD-proxies (count: 5)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 6)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr12:121237691..121298308 View in gBrowse
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