Study Report

Basic Info
Citation Barden, N., M. Harvey, et al. (2006). "Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder." Am J Med Genet B Neuropsychiatr Genet 141B(4): 374-382.
Disease Type Bipolar Disorder
Study Design case-control and family-based
Study Type Mutation study and candidate-gene association study
Sample Size Pedigrees: 485 individuals from 41 families; Case/control sample: 213 unrelated patients and 214 controls
SNP/Region/Marker Size 24 SNPs
Predominant Ethnicity
Population Canadian
Gender 60% female of BPI patients, 55% female of BP II patients

Detail Info

SNPs reported by this study for BD (count: 5)

Haplotypes reported by this study for BD (count: 33)

Genes reported by this study for BD (count: 2)

Gene-gene interactions reported by this study for BD (count: 2)