SNP Report

Basic Info

Name	rs7123390 dbSNP Ensembl
Location	chr11:45869867 - 45869867(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.164936
Functional Annotation	downstream_gene_variant; intron_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000495237, ENST00000496667, ENST00000525110); intron_variant(ENST00000417225, ENST00000443527, ENST00000616080, ENST00000616623); upstream_gene_variant(ENST00000488962)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Sjoholm, L. K.,2010	A/G		Association analysis: allele P-value = 0.16, empirical P-val...... Association analysis: allele P-value = 0.16, empirical P-value = 0.26, OR [95% CI]=1.29[0.9321.58]; genotype, Cochran-Armitage trend P-value = 0.16, Logistic regression: Dominant model, P-value = 0.23, OR[95%CI]=1.24[0.8721.78], Recessive model, P-value = 0.26, OR[95%CI]=1.39[0.7822.49] More...	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CRY2	cryptochrome circadian clock 2	11p11.2	5(3/2/0)

SNPs in LD with rs7123390 (count: 7) View in gBrowse (chr11:45812409..45882062 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs7121775	upstream_gene_variant	0.893[TSI]
rs17787136	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.811[TSI]
rs11038699	intron_variant; non_coding_transcript_variant	0.956[CEU]; 0.947[TSI]
rs11038689	intron_variant; non_coding_transcript_variant	0.893[TSI]
rs11038668	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.839[TSI]
rs4756026	3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant	0.839[TSI]
rs2292910	3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant	0.809[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)