SNP Report

Basic Info

Name	rs3735440 dbSNP Ensembl
Location	chr7:21511452 - 21511452(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.190096
Functional Annotation	3_prime_UTR_variant; NMD_transcript_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000222584, ENST00000448246); NMD_transcript_variant(ENST00000448246)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Zhou, X.,2009	T/C		Allelic association: Caucasian Families for Bipolar Disorder...... Allelic association: Caucasian Families for Bipolar Disorder: TDT: Risk allele is C, MAF=0.34, P-value = 0.019; Chinese Case-Controls for Bipolar Disorder: Risk allele is C, MAF=0.08, P-value = 0.029 More...	Significant association was observed in Caucasian Families f...... Significant association was observed in Caucasian Families for Bipolar Disorder and Chinese Case-Controls for Bipolar Disorder . More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SP4	Sp4 transcription factor	7p15	1(1/0/0)

SNPs in LD with rs3735440 (count: 24) View in gBrowse (chr7:21434992..21513377 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 24)

rs_ID	Functional Annotation	r²[population]
rs9639377	intron_variant; NMD_transcript_variant	1.0[JPT]
rs7811539	intron_variant; NMD_transcript_variant	0.927[CHD]
rs1013716	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.823[CHD]
rs10272006	downstream_gene_variant; intron_variant; NMD_transcript_variant	1.0[CEU]; 0.976[TSI]; 1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs6461567	intron_variant; NMD_transcript_variant	0.908[CEU]
rs12673975	intron_variant; NMD_transcript_variant	0.801[CEU]; 1.0[CHB]; 1.0[JPT]
rs6461565	intron_variant; NMD_transcript_variant	0.83[CEU]; 0.846[CHD]
rs11971316	intron_variant; NMD_transcript_variant	1.0[JPT]
rs6461562	intron_variant; NMD_transcript_variant	0.829[CEU]; 1.0[JPT]
rs12672629	intron_variant; NMD_transcript_variant	0.821[CHB]; 1.0[JPT]
rs7798894	3_prime_UTR_variant; NMD_transcript_variant	0.873[CEU]; 0.877[CHB]; 1.0[JPT]
rs6948810	intron_variant; NMD_transcript_variant	0.85[CEU]; 1.0[CHB]; 1.0[JPT]
rs7792280	intron_variant; NMD_transcript_variant	0.806[CEU]
rs2390539	intron_variant; NMD_transcript_variant	0.864[CHB]; 1.0[JPT]
rs7781732	intron_variant; NMD_transcript_variant	0.864[CEU]; 1.0[JPT]
rs2158414	intron_variant; NMD_transcript_variant	0.877[CHB]; 1.0[JPT]
rs11983472	intron_variant; NMD_transcript_variant	0.823[CEU]; 0.846[CHB]; 1.0[JPT]
rs7780553	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.864[CHB]; 1.0[JPT]
rs6461561	intron_variant; NMD_transcript_variant	0.833[CEU]; 0.951[TSI]; 0.846[CHD]; 0.823[JPT]
rs7811417	intron_variant; NMD_transcript_variant	0.917[CEU]; 0.927[TSI]
rs6461568	intron_variant; NMD_transcript_variant	0.84[CEU]
rs7810841	intron_variant; NMD_transcript_variant	1.0[CEU]; 0.975[TSI]
rs9639378	intron_variant; NMD_transcript_variant	0.826[CEU]; 0.863[CHB]; 1.0[JPT]
rs10269168	intron_variant; NMD_transcript_variant	0.83[CEU]; 1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)