BDgene

SNP Report

Basic Info
Name rs140683 dbSNP Ensembl
Location chr15:26943188 - 26943188(1)
Variant Alleles T/A
Ancestral Allele T
Minor Allele A
Minor Allele Frequence 0.302316
Functional Annotation intron_variant; upstream_gene_variant.
Consequence to Transcript intron_variant(ENST00000335625, ENST00000355395, ENST00000400081); upstream_gene_variant(ENST00000541819)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Otani, K.,2005(a) T/A Chi-square test: for BPD, genotype P-value = 0.59, allele P-...... Chi-square test: for BPD, genotype P-value = 0.59, allele P-value = 0.4; for BPD1, genotype P-value = 0.26, allele P-value = 0.12; for BPD2, genotype P-value = 0.64, allele P-value = 0.38 More... No significant associations were found in BD. No significant associations were found in BD. Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 15q12 6(6/0/0)
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 15q12 3(1/2/0)

SNPs in LD with rs140683 (count: 3) View in gBrowse (chr15:26938442..26971599 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 3)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)