SNP Report

Basic Info
Name |
rs1982350
dbSNP
Ensembl
|
Location |
chr11:13328584 - 13328584(1) |
Variant Alleles |
A/G |
Ancestral Allele |
A |
Minor Allele |
A |
Minor Allele Frequence |
0.499201 |
Functional Annotation |
intron_variant; non_coding_transcript_variant.
|
Consequence to Transcript |
intron_variant(ENST00000389707, ENST00000401424, ENST00000403290, ENST00000403510, ENST00000480685, ENST00000482049, ENST00000527998, ENST00000529050, ENST00000529388, ENST00000529825, ENST00000530357, ENST00000531665, ENST00000533520, ENST00000534544); non_coding_transcript_variant(ENST00000480685) |
No. of Studies |
3 (Positive: 2; Negative: 1; Trend: 0) |
Source |
Literature |
Overlap with SZ? |
YES
|
Overlap with MDD? |
YES
|

SNP related studies (count: 3)

SNP related genes (count: 1)
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.
Literature-origin SNPs (count: 0)
LD-proxies (count: 16)

rs_ID |
Literature-origin SNPs with LD |
Functional Annotation |
r2[population] |
rs11824092
|
|
intron_variant; non_coding_transcript_variant |
1.0[CEU]
|
rs7938307
|
|
intron_variant; non_coding_transcript_variant |
0.85[CEU]
|
rs10832021
|
|
intron_variant; non_coding_transcript_variant |
0.829[CEU]
|
rs10741616
|
|
intron_variant; non_coding_transcript_variant |
0.957[CEU]
|
rs7951393
|
|
intron_variant; non_coding_transcript_variant |
0.829[CEU]
|
rs6486120
|
|
intron_variant; non_coding_transcript_variant |
0.829[CEU]
|
rs6486116
|
|
intron_variant; non_coding_transcript_variant |
0.829[CEU]
|
rs7114573
|
|
intron_variant; non_coding_transcript_variant |
0.829[CEU]
|
rs4757145
|
|
intron_variant; non_coding_transcript_variant; upstream_gene_variant |
0.912[CEU]
|
rs11823635
|
|
intron_variant; non_coding_transcript_variant |
1.0[CEU]
|
rs7396943
|
|
intron_variant; non_coding_transcript_variant; upstream_gene_variant |
0.914[CEU]
|
rs10766077
|
|
intron_variant; non_coding_transcript_variant |
1.0[CEU]
|
rs9633835
|
|
intron_variant; non_coding_transcript_variant |
0.912[CEU]
|
rs11605776
|
|
intron_variant; non_coding_transcript_variant |
0.831[CEU]
|
rs11022762
|
|
intron_variant; non_coding_transcript_variant |
0.956[CEU]
|
rs4757144
|
|
intron_variant; non_coding_transcript_variant; upstream_gene_variant |
0.956[CEU]
|

Overlap with SZ from cross-disorder studies (count: 1)
Reference |
Statistical Result |
Description |
Result Category |
Mansour, H. A., 2006 |
TDT P-value = 0.561, Trends test=0.255 for Pittsburgh SZ/SZA; case-control P-value = 0.028, X2=7.137, df=2 when contrasting genotype distributions |
Contrasting genotype distributions in cases with the population-based sample did not reveal any significant differences by the trend test, although the genotype distribution for ARNTL rs1982350 was noted to be significantly different. |
Positive |

Overlap with MDD from cross-disorder studies (count: 1)
Reference |
Statistical Result |
Description |
Result Category |
Soria, V.,2010 |
X2-tests:allele P-value > 0.05, genotype P-value > 0.05 in all model |
No significant association was observed. |
Negative
|