SNP Report

Basic Info

Name	rs6518189 dbSNP Ensembl
Location	chr21:44444097 - 44444097(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.0992412
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000300481, ENST00000300482, ENST00000397928, ENST00000397932, ENST00000490982, ENST00000498430, ENST00000583496, ENST00000621064)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Roche, S., 2007			TDT allelic P-value = 0.225, X¹⁰=1.471 TDT allelic P-value = 0.225, X¹⁰=1.471	There was no evidence for association in the single-marker a...... There was no evidence for association in the single-marker association analyses More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TRPM2	transient receptor potential cation channel, subfamily M, member 2	21q22.3	5(3/2/0)

SNPs in LD with rs6518189 (count: 12) View in gBrowse (chr21:44444097..44474024 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2838562	downstream_gene_variant	1.0[CEU]
rs762430	downstream_gene_variant	1.0[CEU]
rs6518192	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]
rs9978219	downstream_gene_variant	1.0[CEU]
rs2186932	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]
rs4818925	3_prime_UTR_variant; upstream_gene_variant	1.0[CEU]
rs2838567	downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	0.812[CEU]
rs4818921	downstream_gene_variant	1.0[CEU]
rs2838561	downstream_gene_variant	1.0[CEU]
rs2011324	downstream_gene_variant	1.0[CEU]
rs3804034	3_prime_UTR_variant; upstream_gene_variant	1.0[CEU]
rs9981271	downstream_gene_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)