SNP Report

Basic Info

Name	rs9532988 dbSNP Ensembl
Location	chr13:42075570 - 42075570(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.221645
Functional Annotation	intron_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000261491, ENST00000337343, ENST00000379274); upstream_gene_variant(ENST00000403865)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Zeng, Z.,2011		G	Allelic association: P-value = 0.12, permutated P-value = 0....... Allelic association: P-value = 0.12, permutated P-value = 0.656 for BPD; P-value = 0.196, permutated P-value = 0.831 for BPDI More...	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
DGKH	diacylglycerol kinase, eta	13q13.3	6(3/3/0)
MAPK6PS3	mitogen-activated protein kinase 6 pseudogene 3	13q14.13	Mapped by Literature SNP

SNPs in LD with rs9532988 (count: 24) View in gBrowse (chr13:42066205..42169967 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs9532993	intron_variant	0.81[JPT]
rs9532997	intron_variant	0.823[JPT]
rs4142111	intron_variant	1.0[CHB]; 1.0[JPT]
rs9533005	intron_variant	0.81[JPT]
rs9315887	intron_variant	0.823[JPT]
rs942895	intron_variant	1.0[CHB]; 1.0[JPT]
rs17520002	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.823[JPT]
rs2038882	intron_variant	0.823[JPT]
rs10467371	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.823[JPT]
rs10492444	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.823[JPT]
rs9645983	intron_variant	0.822[JPT]
rs6561033	3_prime_UTR_variant; downstream_gene_variant; intron_variant	1.0[CHB]; 1.0[CHD]; 0.904[JPT]
rs9525569	intron_variant	0.823[JPT]
rs9532998	intron_variant	0.823[JPT]
rs9315886	intron_variant	1.0[JPT]
rs1115398	intron_variant	0.81[JPT]
rs9590664	intron_variant	0.823[JPT]
rs9532986	intron_variant; upstream_gene_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs9594693	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.823[JPT]
rs4318109	downstream_gene_variant; intron_variant	1.0[CHB]
rs9594677	intron_variant	0.823[JPT]
rs627089	intron_variant	0.823[JPT]
rs12856887	intron_variant	0.823[JPT]
rs7336404	intron_variant	1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Zeng, Z.,2011	Allelic association:P-value = 0.282, permutated P-value = 0.942 for SCZ	No significant association was observed after permutation.	Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Zeng, Z.,2011	Allelic association:P-value > 0.05 for MDD.	No significant association was observed after permutation.	Negative