BDgene

SNP Report

Basic Info
Name rs4777974 dbSNP Ensembl
Location chr15:92409060 - 92409060(1)
Variant Alleles G/A
Ancestral Allele A
Minor Allele G
Minor Allele Frequence 0.286741
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000268164, ENST00000539113, ENST00000555434)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
McAuley, E. Z., 2012 G/A P-value = 0.041, Empirical P-value = 0.05, OR (95% CI)=1.36 ...... P-value = 0.041, Empirical P-value = 0.05, OR (95% CI)=1.36 (1.00-1.79) in the Australian bipolar disorder cohort More... Nominally significant association (P < 0.05) was found with ...... Nominally significant association (P < 0.05) was found with 18 SNPs. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 15q26 2(2/0/0)

SNPs in LD with rs4777974 (count: 0) View in gBrowse (chr15:92409060..92409060 )

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
McAuley, E. Z., 2012 P-value > 0.075 Single SNP analysis did not yield significant evidence for association. Negative

Overlap with MDD from cross-disorder studies (count: 0)