Gene Report

Basic Info
Approved Symbol MDGA1
Symbol Alias GPIM, MAMDC3
Approved Name MAM domain containing glycosylphosphatidylinositol anchor 1
Location 6p21
Position chr6:37630679-37699306, -1
External Links HGNC: 19267
Entrez Gene: 266727
Ensembl: ENSG00000112139
UCSC: uc003onu.1
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Li, J.,2011(a) SNP: rs10807187, rs11759115, rs12191311, rs1883901, rs3846881, rs6900617, rs7769372, rs804831, rs9462341, rs9462343, rs989713
Haplotype: rs11759115 - rs7769372(C-C), rs11759115 - rs7769372(T-C), rs11759115 - rs7769372(T-T), rs1883901 - rs10807187 - rs9462343(A-G-G), rs1883901 - rs10807187 - rs9462343(G-G-A), rs1883901 - rs10807187 - rs9462343(G-G-G), rs1883901 - rs10807187 - rs9462343(G-T-G)
The MDGA1 gene may confer risk to schizophrenia and bipolar disorder in Chinese Han population. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 9)

GO terms by PBA (count: 2)

GO terms by database search (count: 7)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 59)

Literature-origin SNPs (count: 11)

LD-proxies (count: 48)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 2)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 0)

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Region: chr6:37630679..37699306 View in gBrowse
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