BDgene

SNP Report

Basic Info
Name rs1615409 dbSNP Ensembl
Location chr1:231547671 - 231547671(1)
Variant Alleles C/A
Ancestral Allele A
Minor Allele C
Minor Allele Frequence 0.460264
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript downstream_gene_variant(ENST00000476913); intron_variant(ENST00000366639, ENST00000413309, ENST00000475168, ENST00000602567, ENST00000602634, ENST00000602825, ENST00000602885, ENST00000602956, ENST00000602962); NMD_transcript_variant(ENST00000602567, ENST00000602634, ENST00000602885, ENST00000602956, ENST00000602962); non_coding_transcript_variant(ENST00000475168, ENST00000602825)
No. of Studies 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Palo, O. M., 2007 C/A P-value = 0.74 in all patients, P-value = 1 in males, P-valu...... P-value = 0.74 in all patients, P-value = 1 in males, P-value = 0.233 in females, with bipolar spectrum disorder More... Negative
Thomson, P. A.,2005(a) Single-Marker Analysis: allele frequency, for BP, P-value = ...... Single-Marker Analysis: allele frequency, for BP, P-value = 0.77 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TSNAX translin-associated factor X 1q42.2 4(3/1/0)
DISC1 disrupted in schizophrenia 1 1q42.1 18(10/7/1)

SNPs in LD with rs1615409 (count: 0) View in gBrowse (chr1:231547671..231547671 )

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Thomson, P. A.,2005(a) Single-Marker Analysis:allele frequency, for SZ, P-value = 0.86 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 0)