SNP Report

Basic Info

Name	rs10893385 dbSNP Ensembl
Location	chr11:125479025 - 125479025(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.495208
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000278919, ENST00000392709, ENST00000527350, ENST00000532981, ENST00000533294, ENST00000577924); non_coding_transcript_variant(ENST00000392709, ENST00000527350, ENST00000532981, ENST00000533294)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Hodgkinson, C. A., 2007	A/G		Allelic P-value = 0.576, genotypic P-value = 0.481 in Cauc...... Allelic P-value = 0.576, genotypic P-value = 0.481 in Caucasians. More...	No association to bipolar disorder was found for any of the ...... No association to bipolar disorder was found for any of the nine markers typed in these populations at the allelic or the genotypic level. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	11q24.2	2(0/2/0)

SNPs in LD with rs10893385 (count: 4) View in gBrowse (chr11:125479025..125554521 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs2845846	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]; 0.956[TSI]; 0.937[ASW]
rs2845853		0.917[CEU]; 0.933[TSI]; 0.937[ASW]
rs2702010	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.917[CEU]; 0.956[TSI]; 0.937[ASW]
rs2701999		0.877[CEU]; 0.844[TSI]; 0.937[ASW]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Hodgkinson, C. A., 2007	Allelic P-value = 0.625, genotypic P-value = 0.551 in Caucasians. Allelic P-value = 0.450, genotypic P-value = 0.262 in African Americans.	No association to schizophrenia was found for any of the nine markers typed in these populations at the allelic or the genotypic level.	Negative

Overlap with MDD from cross-disorder studies (count: 0)