Gene Report

Basic Info
Approved Symbol NRGN
Symbol Alias RC3
Approved Name neurogranin (protein kinase C substrate, RC3)
Location 11q24
Position chr11:124739846-124747210, 1
External Links HGNC: 8000
Entrez Gene: 4900
Ensembl: ENSG00000154146
UCSC: uc001qar.2
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Williams, H. J.,2011 SNP: rs12807809 Using data sets entirely independent of their original discoveries, we observed nominally significant evidence (P < 0.05) that the extended MHC region is associated with BD. Positive Comment on Study
Steinberg, S.,2012 SNP: rs12807809 No significant association was observed. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 5)

GO terms by PBA (count: 2)

GO terms by database search (count: 3)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 4)

Related other genetic factors
Gene related SNPs (count: 3)

Literature-origin SNPs (count: 3)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 4)

Gene relationship with MDD

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Region: chr11:124739846..124747210 View in gBrowse
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