SNP Report

Basic Info

Name	rs1411771 dbSNP Ensembl
Location	chr1:232039029 - 232039029(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	C
Minor Allele Frequence	0.366414
Functional Annotation	3_prime_UTR_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000366637, ENST00000439617, ENST00000620189, ENST00000622252)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Palo, O. M., 2007	T/C		P-value = 0.406 in all patients, P-value = 0.296 in males, P...... P-value = 0.406 in all patients, P-value = 0.296 in males, P-value = 1 in females, with bipolar spectrum disorder More...		Negative
Thomson, P. A.,2005(a)			Single-Marker Analysis: allele frequency, for BP, P-value = ...... Single-Marker Analysis: allele frequency, for BP, P-value = 0.89 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TSNAX	translin-associated factor X	1q42.2	4(3/1/0)
DISC1	disrupted in schizophrenia 1	1q42.1	18(10/7/1)

SNPs in LD with rs1411771 (count: 3) View in gBrowse (chr1:232038427..232041241 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs9729179	3_prime_UTR_variant	1.0[CEU]; 1.0[TSI]
rs16856322	3_prime_UTR_variant; downstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs9308481	3_prime_UTR_variant	0.809[CEU]; 0.828[TSI]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Thomson, P. A.,2005(a)	Single-Marker Analysis:allele frequency, for SZ, P-value = 0.9	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 0)