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SNP Report
Basic Info
| Name | rs2239848 dbSNP Ensembl | ||
|---|---|---|---|
| Location | chr22:49823106 - 49823106(1) | ||
| Variant Alleles | G/A | ||
| Ancestral Allele | G | ||
| Minor Allele | A | ||
| Minor Allele Frequence | 0.141174 | ||
| Functional Annotation | NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; synonymous_variant. | ||
| Consequence to Transcript | NMD_transcript_variant(ENST00000438393); non_coding_transcript_exon_variant(ENST00000459821, ENST00000494833); non_coding_transcript_variant(ENST00000459821, ENST00000494833); synonymous_variant(ENST00000216267, ENST00000404034, ENST00000404760, ENST00000438393, ENST00000457780) | ||
| No. of Studies | 2 (Positive: 0; Negative: 2; Trend: 0) | ||
| Source | Literature | ||
| Overlap with SZ? | YES | ||
| Overlap with MDD? | NO | ||
SNP related studies (count: 2)
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| BRD1 | bromodomain containing 1 | 22q13.33 | 2(2/0/0) |
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.
Literature-origin SNPs (count: 0)
LD-proxies (count: 1)
Overlap with SZ from cross-disorder studies (count: 2)
| Reference | Statistical Result | Description | Result Category |
|---|---|---|---|
| Nyegaard, M., 2010 | P-value = 0.8, OR=0.9 in UK/DK sample | Nominal significant association with SZ | Positive |
| Severinsen, J. E., 2006 (b) | P-value = 1 in SZ, P-value = 0.3983 in BD and SZ | Negative |
Overlap with MDD from cross-disorder studies (count: 0)