Gene Report

Basic Info
Approved Symbol ESR1
Previous Symbol ESR
Symbol Alias NR3A1, Era
Approved Name estrogen receptor 1
Location 6q24-q27
Position chr6:151656691-152129619, 1
External Links HGNC: 3467
Entrez Gene: 2099
Ensembl: ENSG00000091831
UCSC: uc003qon.4
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Jones, I.,2000 Haplotype: (ESR1_XbaI polymorphism) - (ESR1_PvuII polymorphism)() We could exclude these polymorphisms from an important contribution to susceptibility to bipolar disorder with a high level of confidence. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 62)

GO terms by PBA (count: 7)

GO terms by database search (count: 55)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 4)

Gene related interactors from protein-protein interactions data in HPRD (count: 182)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 4)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 3)

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Region: chr6:151656691..152129619 View in gBrowse
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