SNP Report

Basic Info

Name	rs11487077 dbSNP Ensembl
Location	chrCHR_HSCHR7_1_CTG4_4:103225660 - 103225660(-1)
Variant Alleles	A/C
Ancestral Allele	A
Minor Allele	C
Minor Allele Frequence	0.0449281
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000341533, ENST00000414118, ENST00000417955, ENST00000420631, ENST00000422589, ENST00000427257, ENST00000465647); NMD_transcript_variant(ENST00000420631, ENST00000422589); non_coding_transcript_variant(ENST00000414118, ENST00000631820, ENST00000631940, ENST00000632400, ENST00000632491, ENST00000633207, ENST00000631820, ENST00000631940, ENST00000632400, ENST00000632491, ENST00000633207)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Pisanu, C., 2013	C/A		logistic regression, P-value=0.033, OR=1.55 logistic regression, P-value=0.033, OR=1.55	Logistic regression analysis showed nominal association betw...... Logistic regression analysis showed nominal association between rs11487077 located in NAPE-PLD and BD, but not with lithium response. Separating the samples into two groups of BDI and BDII showed that these two SNPs were nominally associated with BDI but not with BDII. However, odds ratio (OR) was not significantly increased in comparison to the whole sample (SNPrs11487077, OR=1.55 in the whole sample and 1.63 in the BDI sample). More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NAPEPLD	N-acyl phosphatidylethanolamine phospholipase D	7q22.1	1(1/0/0)

SNPs in LD with rs11487077 (count: 1) View in gBrowse (chrCHR_HSCHR7_1_CTG4_4:102926722..103225660 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs4398822		intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.879[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)