Gene Report

Basic Info
Approved Symbol QDPR
Symbol Alias DHPR, PKU2, SDR33C1
Approved Name quinoid dihydropteridine reductase
Name Alias 6,7-dihydropteridine reductase, "short chain dehydrogenase/reductase family 33C, member 1"
Location 4p15.31
Position chr4:17460261-17512234, -1
External Links HGNC: 9752
Entrez Gene: 5860
Ensembl: ENSG00000151552
UCSC: uc003gpd.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Shi, J., 2008 (b) SNP: rs744731
Haplotype: rs2597758 - rs1031326 - rs744731 - rs2597778(AGGA)
rs744731 in the QDPR reached gene-wide association (permutation P<0.05 for all SNPs of each gene). . None of these associations survived multiple testing for its own system (e.g., glutamatergic or serotoninergic) or all the five systems taken together (permutation adjusted P>0.05)。 Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 22)

GO terms by PBA (count: 0)

GO terms by database search (count: 22)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 3)

Literature-origin SNPs (count: 1)

LD-proxies (count: 2)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

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Region: chr4:17460261..17512234 View in gBrowse
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