BDgene

SNP Report

Basic Info
Name rs1007023 dbSNP Ensembl
Location chr12:71994594 - 71994594(1)
Variant Alleles G/T
Ancestral Allele T
Minor Allele G
Minor Allele Frequence 0.120208
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000333850)
No. of Studies 3 (Positive: 1; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Yosifova, A.,2009 G/T Allelic association: 1st screening: P-value = 0.069, 2nd scr...... Allelic association: 1st screening: P-value = 0.069, 2nd screening: P-value = 1, total: P-value = 0.12 More... Significant association was observed Significant association was observed Positive
Lopez, V. A., 2007 G/T FBAT P-value = 0.055, Z=-1.916 in the NIMH 'Wave 3' Sample FBAT P-value = 0.055, Z=-1.916 in the NIMH 'Wave 3' Sample this marker displayed association with BPAD at the p=0.0553 ...... this marker displayed association with BPAD at the p=0.0553 level of significance, although it was informative in only 42 families. More... Negative
Roche, S.,2009 G TDT: X2=0.053, P-value = 0.8185 TDT: X2=0.053, P-value = 0.8185 No significant association was observed No significant association was observed Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TPH2 tryptophan hydroxylase 2 12q15 13(10/3/0)

SNPs in LD with rs1007023 (count: 23) View in gBrowse (chr12:71955510..72011279 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 23)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016