SNP Report

Basic Info

Name	rs10502151 dbSNP Ensembl
Location	chr11:111853410 - 111853410(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.326478
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; missense_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant. Polyphen Annotation: benign(ENST00000614444, ENST00000398006, ENST00000531154, ENST00000616540, ENST00000622211) SIFT Annotation: deleterious(ENST00000614444); tolerated(ENST00000398006, ENST00000531154, ENST00000616540, ENST00000622211)
Consequence to Transcript	3_prime_UTR_variant(ENST00000613181, ENST00000618252, ENST00000619129); downstream_gene_variant(ENST00000612489); missense_variant(ENST00000614444, ENST00000398006, ENST00000531154, ENST00000616540, ENST00000622211); NMD_transcript_variant(ENST00000613181, ENST00000618252, ENST00000619129); non_coding_transcript_exon_variant(ENST00000527714, ENST00000530851); non_coding_transcript_variant(ENST00000527714, ENST00000530851)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Baysal, B. E., 2006	G/A		TDT P-value = 0.58, X²1=0.299 in PITT; TDT P-val...... TDT P-value = 0.58, X²1=0.299 in PITT; TDT P-value = 0.91, X²1=0.012 in NIMH More...	None of the common alleles of the five markers yielded stati...... None of the common alleles of the five markers yielded statistically significant evidence for transmission disequilibrium. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ALG9	ALG9, alpha-1,2-mannosyltransferase	11q23	1(0/1/0)

SNPs in LD with rs10502151 (count: 32) View in gBrowse (chr11:111734491..112045923 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 32)

rs_ID	Functional Annotation	r²[population]
rs3809033	3_prime_UTR_variant; downstream_gene_variant; intron_variant; upstream_gene_variant	0.821[TSI]
rs736650	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.948[CEU]; 0.949[TSI]
rs7949136	intron_variant; NMD_transcript_variant	0.821[TSI]
rs6589259	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	0.821[TSI]
rs10502150	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]; 0.974[TSI]
rs11214049	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.821[TSI]
rs10891290	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.854[CEU]
rs1529330	downstream_gene_variant; upstream_gene_variant	0.948[CEU]; 0.974[TSI]
rs10502152	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	0.897[TSI]
rs2081508	intron_variant; non_coding_transcript_variant	0.82[TSI]
rs10789856	intron_variant; non_coding_transcript_variant	0.821[TSI]
rs1320664	downstream_gene_variant; intron_variant	0.875[TSI]
rs3829258	intron_variant; non_coding_transcript_variant; splice_region_variant; upstream_gene_variant	0.855[CEU]; 0.925[TSI]
rs10789855	intron_variant; non_coding_transcript_variant	0.821[TSI]
rs10502149	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1.0[CEU]; 0.974[TSI]
rs35823624	intron_variant; non_coding_transcript_variant	0.821[TSI]
rs10891313	intron_variant; NMD_transcript_variant; upstream_gene_variant	0.821[TSI]
rs3867465	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.894[CEU]; 0.804[TSI]
rs12284944	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	0.875[TSI]
rs12225443	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.821[TSI]
rs10891314	3_prime_UTR_variant; missense_variant; NMD_transcript_variant	0.817[TSI]
rs2303436	downstream_gene_variant; missense_variant; NMD_transcript_variant	0.818[TSI]
rs10891291	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	0.855[CEU]; 0.924[TSI]
rs2007211	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs7124433	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	0.834[CEU]
rs11214005	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	1.0[CEU]; 0.974[TSI]
rs10891301	intron_variant; non_coding_transcript_variant	0.839[TSI]
rs2105619	intron_variant; non_coding_transcript_variant	0.816[TSI]
rs4252591	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	0.895[TSI]
rs1648390	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs10891303	downstream_gene_variant; intron_variant; upstream_gene_variant	0.821[TSI]
rs10502148	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.855[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)