SNP Report

Basic Info

Name	rs2035645 dbSNP Ensembl
Location	chr15:92403096 - 92403096(1)
Variant Alleles	T/G
Ancestral Allele	G
Minor Allele	T
Minor Allele Frequence	0.309704
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000268164, ENST00000539113, ENST00000555434)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
McAuley, E. Z., 2012	A/C		P-value = 0.042, Empirical P-value = 0.06, OR (95% CI)=1.36 ...... P-value = 0.042, Empirical P-value = 0.06, OR (95% CI)=1.36 (1.00-1.78) in the Australian bipolar disorder cohort More...	Nominally significant association (P < 0.05) was found with ...... Nominally significant association (P < 0.05) was found with 18 SNPs. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	15q26	2(2/0/0)

SNPs in LD with rs2035645 (count: 3) View in gBrowse (chr15:92401634..92406579 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs11074067	intron_variant	0.822[CEU]
rs11074066	intron_variant	1.0[CEU]; 0.91[TSI]
rs881770	intron_variant	0.85[CEU]; 0.843[TSI]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
McAuley, E. Z., 2012	P-value > 0.075	Single SNP analysis did not yield significant evidence for association.	Negative

Overlap with MDD from cross-disorder studies (count: 0)