SNP Report

Basic Info

Name	rs2839350 dbSNP Ensembl
Location	chr21:46597307 - 46597307(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.181909
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000291700, ENST00000367071, ENST00000397648)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Roche, S., 2007	G/A		TDT allelic P-value = 0.022, X³=5.255 in BPI; P-...... TDT allelic P-value = 0.022, X³=5.255 in BPI; P-value = 0.016, X³=5.818 in BPI and psychosis More...	There was modest evidence for association of S100B SNP M2 wi...... There was modest evidence for association of S100B SNP M2 with BPAD, markers M2 was more significantly associated with BPI and psychosis More...	Positive
Yosifova, A.,2009	A/G		Allelic association: P-value = 0.11 Allelic association: P-value = 0.11	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
S100B	S100 calcium binding protein B	21q22.3	2(1/1/0)

SNPs in LD with rs2839350 (count: 0) View in gBrowse (chr21:46597307..46597307 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)