SNP Report

Basic Info

Name	rs562047 dbSNP Ensembl
Location	chrCHR_HSCHR6_MHC_QBL_CTG1:31806321 - 31806321(1)
Variant Alleles	C/G
Ancestral Allele	G
Minor Allele	C
Minor Allele Frequence	0.228235
Functional Annotation	intron_variant; missense_variant; upstream_gene_variant. Polyphen Annotation: probably damaging(ENST00000375651, ENST00000430065, ENST00000441618, ENST00000433487); benign(ENST00000400040) SIFT Annotation: tolerated - low confidence(ENST00000400040); deleterious - low confidence(ENST00000375651, ENST00000430065, ENST00000441618, ENST00000433487)
Consequence to Transcript	intron_variant(ENST00000608703); missense_variant(ENST00000375651); upstream_gene_variant(ENST00000375654, ENST00000422919, ENST00000430065, ENST00000426095, ENST00000449876, ENST00000441618, ENST00000456772, ENST00000452298, ENST00000433487, ENST00000417601, ENST00000383389, ENST00000400040, ENST00000383390)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Pae, C. U.,2009	G/C		ANOVA: P-value = 0.04 ANOVA: P-value = 0.04	Significant association was observed Significant association was observed	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
HSPA1A	heat shock 70kDa protein 1A	6p21.3	2(2/0/0)
HSPA1L	heat shock 70kDa protein 1-like	6p21.3	Mapped by Literature SNP

SNPs in LD with rs562047 (count: 0) View in gBrowse (chrCHR_HSCHR6_MHC_QBL_CTG1:31806321..31806321 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)