SNP |
Related Gene(s) |
Allele Change |
Risk Allele |
Statistical Values |
Author Comments |
Result Category |
rs967771 |
GABRB2
|
A/G |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0278, Gene-wide P-value = 0.2058 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs9450594 |
HTR1E
|
A/C |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0248, Gene-wide P-value = 0.0579 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs9456 |
TMEM186
ABAT
|
A/T |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0049, Gene-wide P-value = 0.0859 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs744731 |
QDPR
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0055, Gene-wide P-value = 0.014 (P values were based on permutation for all SNPs in each gene).
|
rs744731 in the QDPR gene reached gene-wide association. Non......
rs744731 in the QDPR gene reached gene-wide association. None of these associations survived multiple testing for its own system (e.g., glutamatergic or serotoninergic) or all the five systems taken together.
More...
|
Positive
|
rs915841 |
ABCG1
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0494, Gene-wide P-value = 0.5205 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs6580038 |
GRIA1
RN7SL177P
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0264, Gene-wide P-value = 0.3586 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs733457 |
GRM4
|
A/C |
C |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0249, Gene-wide P-value = 0.1399 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs623580 |
TPH1
|
A/T |
T |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0413, Gene-wide P-value = 0.0809 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs6443074 |
GRM7
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.03, Gene-wide P-value = 0.5674 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs5925155 |
GABRA3
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0359, Gene-wide P-value = 0.2428 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs592807 |
GRIA3
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0267, Gene-wide P-value = 0.4036 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs5028114 |
HTR4
|
A/G |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0432, Gene-wide P-value = 0.2378 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs592403 |
GABRB2
|
A/C |
C |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0198, Gene-wide P-value = 0.2517 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs37022 |
SLC6A3
|
A/T |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0371, Gene-wide P-value = 0.2108 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs362853 |
GRM1
|
A/C |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0443, Gene-wide P-value = 0.3766 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs4790694 |
ARRB2
|
A/C |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0251, Gene-wide P-value = 0.0669 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs3818275 |
SLC1A2
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0325, Gene-wide P-value = 0.3556 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs2926835 |
GRIA1
|
A/T |
T |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0036, Gene-wide P-value = 0.029 (P values were based on permutation for all SNPs in each gene).
|
rs2926835 in the GRIA1 gene reached gene-wide association. N......
rs2926835 in the GRIA1 gene reached gene-wide association. None of these associations survived multiple testing for its own system (e.g., glutamatergic or serotoninergic) or all the five systems taken together.
More...
|
Positive
|
rs2731877 |
SLC1A3
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0224, Gene-wide P-value = 0.1948 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs329037 |
GRM7
|
A/C |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0059, Gene-wide P-value = 0.3766 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs2926837 |
GRIA1
|
C/G |
C |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0294, Gene-wide P-value = 0.3127 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs2268115 |
GRIN2B
|
A/C |
C |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0352, Gene-wide P-value = 0.6743 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs220592 |
GRIN2B
|
A/C |
C |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0449, Gene-wide P-value = 0.7223 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs252952 |
GABRB2
|
A/C |
C |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0066, Gene-wide P-value = 0.1039 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs2453737 |
DRD1
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0233, Gene-wide P-value = 0.0989 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs1799281 |
GRIN2D
GRWD1
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0029, Gene-wide P-value = 0.026 (P values were based on permutation for all SNPs in each gene).
|
rs1799281 in the GRIN2D gene reached gene-wide association. ......
rs1799281 in the GRIN2D gene reached gene-wide association. None of these associations survived multiple testing for its own system (e.g., glutamatergic or serotoninergic) or all the five systems taken together.
More...
|
Positive
|
rs1645660 |
SLC1A3
|
A/G |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0292, Gene-wide P-value = 0.2927 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs2168631 |
DRD1
|
A/G |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0475, Gene-wide P-value = 0.1898 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs2036109 |
ADRA1A
|
A/C |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0268, Gene-wide P-value = 0.1728 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs1273394 |
ABAT
|
A/C |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0345, Gene-wide P-value = 0.6224 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs12754 |
ADCY1
SEPT7P2
|
A/C |
C |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.007, Gene-wide P-value = 0.1099 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs1461225 |
GRIA1
|
A/C |
C |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0056, Gene-wide P-value = 0.0769 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs162724 |
GRM7
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0205, Gene-wide P-value = 0.3037 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs1042009 |
ADCY1
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0122, Gene-wide P-value = 0.0829 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs1048101 |
ADRA1A
|
A/G |
G |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0306, Gene-wide P-value = 0.1888 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs10515827 |
GABRB2
|
A/G |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0206, Gene-wide P-value = 0.1409 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs10743152 |
TH
MIR4686
|
A/G |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.049, Gene-wide P-value = 0.2058 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|
rs10102186 |
ADRA1A
|
A/G |
A |
Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0139, Gene-wide P-value = 0.1728 (P values were based on permutation for all SNPs in each gene).
|
|
Positive
|