BDgene

SNP Report

Basic Info
Name rs4586379 dbSNP Ensembl
Location chr15:92377797 - 92377797(1)
Variant Alleles C/T
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.245607
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
McAuley, E. Z., 2012 G/A P-value = 0.004, Empirical P-value = 0.006, OR (95% CI)=0.61...... P-value = 0.004, Empirical P-value = 0.006, OR (95% CI)=0.61 (0.43-0.85) in the Australian bipolar disorder cohort More... Nominally significant association (P < 0.05) was found with ...... Nominally significant association (P < 0.05) was found with 18 SNPs. Association with 14 of these SNPs held true when empirical P values were obtained through 10, 000 replicate permutations. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 15q26 2(2/0/0)

SNPs in LD with rs4586379 (count: 3) View in gBrowse (chr15:92371565..92377797 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 3)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
McAuley, E. Z., 2012 P-value > 0.075 Single SNP analysis did not yield significant evidence for association. Negative

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016