BDgene

SNP Report

Basic Info
Name rs2273773 dbSNP Ensembl
Location chr10:67906841 - 67906841(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.127196
Functional Annotation non_coding_transcript_exon_variant; non_coding_transcript_variant; synonymous_variant.
Consequence to Transcript non_coding_transcript_exon_variant(ENST00000473922); non_coding_transcript_variant(ENST00000473922); synonymous_variant(ENST00000212015, ENST00000403579, ENST00000406900, ENST00000432464)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kishi, T.,2011(a) T/C For BP, X2 test: genotype, X2(2df)=4.7...... For BP, X2 test: genotype, X2(2df)=4.76, P-value = 0.0926; allele, X2(2df)=3.53, P-value = 0.0604 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SIRT1 sirtuin 1 10q21 1(0/1/0)

SNPs in LD with rs2273773 (count: 14) View in gBrowse (chr10:67804053..67911059 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 14)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Kishi, T.,2011(a) For SZ, X2 test:genotype, X2(2df)=0.0744, P-value = 0.963;allele, X2(2df)=0.0644, P-value = 0.8 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 0)