SNP Report

Basic Info
Name rs2171363 dbSNP Ensembl
Location chr12:71966484 - 71966484(1)
Variant Alleles A/G
Ancestral Allele A
Minor Allele G
Minor Allele Frequence 0.403355
Functional Annotation downstream_gene_variant; intron_variant.
Consequence to Transcript downstream_gene_variant(ENST00000546576); intron_variant(ENST00000333850)
No. of Studies 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Chen, S., 2014 C/T Allele frequency: P-value=0.827183, Permutated P-value=0.999...... Allele frequency: P-value=0.827183, Permutated P-value=0.9995; Genotype frequency: P-value=0.212909, H-W P-value=0.551496(case), H-W P-value=0.061565(control). More... No significant associations were observed. No significant associations were observed. Negative
Roche, S.,2009 T TDT: X2=2.945, P-value = 0.0861 TDT: X2=2.945, P-value = 0.0861 No significant association was observed No significant association was observed Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TPH2 tryptophan hydroxylase 2 12q15 13(10/3/0)

SNPs in LD with rs2171363 (count: 20) View in gBrowse (chr12:71953020..72013053 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 20)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)