BDgene

SNP Report

Basic Info
Name rs12778366 dbSNP Ensembl
Location chr10:67883321 - 67883321(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.113419
Functional Annotation upstream_gene_variant.
Consequence to Transcript upstream_gene_variant(ENST00000212015, ENST00000432464, ENST00000473922, ENST00000497639)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kishi, T.,2011(a) T/C For BP, X2 test: genotype, X2(2df)=1.4...... For BP, X2 test: genotype, X2(2df)=1.4, P-value = 0.497; allele, X2(2df)=0.529, P-value = 0.467 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SIRT1 sirtuin 1 10q21 1(0/1/0)

SNPs in LD with rs12778366 (count: 21) View in gBrowse (chr10:67780908..68076644 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 21)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Kishi, T.,2011(a) For SZ, X2 test:genotype, X2(2df)=1.21, P-value = 0.545;allele, X2(2df)=0.555, P-value = 0.456 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 0)