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SNP Report
Basic Info
| Name | rs4474484 dbSNP Ensembl | ||
|---|---|---|---|
| Location | chr12:72021666 - 72021666(1) | ||
| Variant Alleles | A/G | ||
| Ancestral Allele | G | ||
| Minor Allele | G | ||
| Minor Allele Frequence | 0.463259 | ||
| Functional Annotation | intron_variant. | ||
| Consequence to Transcript | intron_variant(ENST00000333850) | ||
| No. of Studies | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
| Overlap with SZ? | NO | ||
| Overlap with MDD? | YES | ||
SNP related studies (count: 1)
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| TPH2 | tryptophan hydroxylase 2 | 12q15 | 13(10/3/0) |
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.
Literature-origin SNPs (count: 0)
LD-proxies (count: 14)
Overlap with SZ from cross-disorder studies (count: 0)
Overlap with MDD from cross-disorder studies (count: 1)
| Reference | Statistical Result | Description | Result Category |
|---|---|---|---|
| Van Den Bogaert, A., 2006 (a) | genotypic P-value = 0.38, allelic P-value = 0.35 | Negative |