SNP Report

Basic Info

Name	rs17844778 dbSNP Ensembl
Location	chr4:8581585 - 8581585(1)
Variant Alleles	A/C
Ancestral Allele	C
Minor Allele	C
Minor Allele Frequence	0.15016
Functional Annotation	downstream_gene_variant; intron_variant; missense_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant. Polyphen Annotation: benign(ENST00000382487, ENST00000514302) SIFT Annotation: tolerated(ENST00000382487, ENST00000514302)
Consequence to Transcript	downstream_gene_variant(ENST00000503448, ENST00000503981); intron_variant(ENST00000509216); missense_variant(ENST00000382487, ENST00000514302); NMD_transcript_variant(ENST00000514302); non_coding_transcript_variant(ENST00000509216); upstream_gene_variant(ENST00000504255)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Underwood, S. L., 2006	A/C		no P-value given in the text no P-value given in the text	No single-marker association was detected with any other SNP...... No single-marker association was detected with any other SNP, in the males or in the individuals with BPAD. More...	Negative
Yosifova, A.,2009	A/C		Allelic association: P-value = 0.39 Allelic association: P-value = 0.39	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GPR78	G protein-coupled receptor 78	4p16.1	2(2/0/0)

SNPs in LD with rs17844778 (count: 0) View in gBrowse (chr4:8581585..8581585 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Underwood, S. L., 2006	no P-value given in the text	No single-marker association was detected.	Negative

Overlap with MDD from cross-disorder studies (count: 0)