SNP Report

Basic Info

Name	rs3789327 dbSNP Ensembl
Location	chr11:13363769 - 13363769(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.458666
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000529388); intron_variant(ENST00000389707, ENST00000401424, ENST00000403290, ENST00000403482, ENST00000403510, ENST00000497429, ENST00000530357); non_coding_transcript_variant(ENST00000497429); upstream_gene_variant(ENST00000534102)
No. of Studies	3 (Positive: 2; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 3)

Reference	Allele Change	Statistical Values	Author Comments	Result Category
Soria, V.,2010		X²-tests: allele P-value = 0.023, Model Recessive...... X²-tests: allele P-value = 0.023, Model Recessive, genotype P-value = 0.013, OR(95%CI)=0.60 (0.39-0.90) More...	Significant association was found in BD. Significant association was found in BD.	Positive
Dmitrzak-Weglarz, M. P., 2014	T/C	BPDII: P-value= 0.0405, FDR=0.1698, OR=0.74, 95%CI=0.56-0.99...... BPDII: P-value= 0.0405, FDR=0.1698, OR=0.74, 95%CI=0.56-0.99. More...	Significant association was observed. Significant association was observed.	Positive
Yosifova, A.,2009	G/A	Allelic association: P-value = 0.15 Allelic association: P-value = 0.15	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	11p15	7(5/2/0)

SNPs in LD with rs3789327 (count: 0) View in gBrowse (chr11:13363769..13363769 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soria, V.,2010	X²-tests:allele P-value > 0.05, genotype P-value > 0.05 in all model	No significant association was observed.	Negative