BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

Search Gene with Disease Search Gene1 with Disease

Study Report

Comment on Study

View All Comments on Study

Basic Info

Reference	Zhang, Z.,2009(a) PMID: 19339914
Citation	Zhang, Z., Y. Li, et al. (2009). First evidence of association between G72 and bipolar disorder in the Chinese Han population. Psychiatr Genet 19(3): 151-153.
Disease Type	Bipolar Disorder
Study Design	case-control
Study Type	Candidate-gene association study
Sample Size	475 unrelated BPD patients and 588 normal controls
SNP/Region/Marker Size	5 SNPs
Predominant Ethnicity	Mongloid
Population	Chinese
Gender	BPD patients (255 men, 220 women),normal controls (178 men, 410 women)

Detail Info

SNPs reported by this study for BD (count: 5)

SNP	Related Gene(s)	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
rs2391191	DAOA DAOA-AS1	A/G		Allelic association: Odds ratio (95% CI)=1.12(0.93-1.34), P-value = 0.224	No significant association was observed No significant association was observed	Negative
rs3918342	DAOA	A/G		Allelic association: Odds ratio (95% CI)=0.92(0.78-1.10), P-value = 0.367	No significant association was observed No significant association was observed	Negative
rs3916965	DAOA	A/G		Allelic association: Odds ratio (95% CI)=0.89(0.74-1.07), P-value = 0.229	No significant association was observed No significant association was observed	Negative
rs778294	DAOA DAOA-AS1	A/G		Allelic association: Odds ratio (95% CI)=0.77(0.59-1.00), P-value = 0.047	Significant association was observed Significant association was observed	Positive
rs778293	DAOA	A/G		Allelic association: Odds ratio (95% CI)=1.33(1.10-1.60), P-value = 0.003	Significant association was observed Significant association was observed	Positive

Haplotypes reported by this study for BD (count: 5)

Markers	Haplotype	Related Gene(s)/Region(s)	Statistical Values	Author Comments	Result Category
rs778293 - rs3918342	A-A	DAOA	Haplotypic association:P-value = 0.67	No significant association was found . No significant association was found .	Negative
rs778294 - rs778293	G-A	DAOA	Haplotypic association:P-value = 6.0E-04	Significant association was found in global P-value and indi...... Significant association was found in global P-value and individual P-value. More...	Positive
rs778294 - rs778293	G-G	DAOA	Haplotypic association:P-value = 0.022	Significant association was found in global P-value and indi...... Significant association was found in global P-value and individual P-value. More...	Positive
rs778293 - rs3918342	A-G	DAOA	Haplotypic association:P-value = 0.01	Significant association was found in global P-value and indi...... Significant association was found in global P-value and individual P-value. More...	Positive
rs778293 - rs3918342	G-G	DAOA	Haplotypic association:P-value = 0.064	No significant association was found . No significant association was found .	Negative

Genes reported by this study for BD (count: 1)