BDgene

Gene Report

Basic Info
Approved Symbol GSTM1
Previous Symbol GST1
Symbol Alias MU, H-B
Approved Name glutathione S-transferase mu 1
Previous Name glutathione S-transferase M1
Location 1p13.3
Position chr1:109687814-109709039, 1
External Links HGNC: 4632
Entrez Gene: 2944
Ensembl: ENSG00000134184
UCSC: uc001dyk.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Mohammadynejad, P.,2011 Haplotype: (GSTM1_positive/null) - (GSTT1_positive/null)((GSTM1_null)-(GSTT1_null)), (GSTM1_positive/null) - (GSTT1_positive/null)((GSTM1_null)-(GSTT1_positive)), (GSTM1_positive/null) - (GSTT1_positive/null)((GSTM1_positive)-(GSTT1_null))
Other variant: GSTM1_positive/null
The present finding indicated that GSTM1 and GSTT1 are candidate polymorphisms for susceptibility to BDP among adolescents. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 13)

GO terms by PBA (count: 2)

GO terms by database search (count: 11)


Gene related KEGG pathways (count: 3)

KEGG pathways by PBA (count: 2)

KEGG pathways by database search (count: 1)


Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 4)


Gene relationship with MDD

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Region: chr1:109687814..109709039 View in gBrowse
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