Gene Report

Basic Info
Approved Symbol MOV10L1
Symbol Alias DJ402G11.8, DKFZp434B0717, CHAMP
Approved Name Mov10 RISC complex RNA helicase like 1
Previous Name Mov10 (mouse)-like 1, "Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)"
Name Alias cardiac helicase activated by MEF2C protein
Location 22q13.33
Position chr22:50089879-50161690, 1
External Links HGNC: 7201
Entrez Gene: 54456
Ensembl: ENSG00000073146
UCSC: uc003bjj.3
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Severinsen, J. E., 2006 (b) SNP: rs2272843, rs3810971
Haplotype: rs715519 - rs2272843(), rs715519 - rs2272843 - rs3810971(), rs715519 - rs2272843 - rs3810971 - rs137932(), rs916005 - rs715519 - rs2272843(), rs916005 - rs715519 - rs2272843 - rs3810971(), rs2272843 - rs3810971(), rs2272843 - rs3810971 - rs137932(), rs2272843 - rs3810971 - rs137932 - rs137931(), rs3810971 - rs137932(), rs3810971 - rs137932 - rs137931(), rs3810971 - rs137932 - rs137931 - rs6010260()
The results do not support an association of the gene with BD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 10)

GO terms by PBA (count: 1)

GO terms by database search (count: 9)

Gene related KEGG pathways (count: 2)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 2)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 98)

Literature-origin SNPs (count: 8)

LD-proxies (count: 90)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr22:50089879..50161690 View in gBrowse
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