Gene Report

Basic Info
Approved Symbol ADCY9
Symbol Alias AC9
Approved Name adenylate cyclase 9
Location 16p13.3
Position chr16:3953387-4116185, -1
External Links HGNC: 240
Entrez Gene: 115
Ensembl: ENSG00000162104
UCSC: uc002cvx.3
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Toyota, T.,2002 Haplotype: (ADCY9_2316A>G) - ( ADCY9_(TTTA)n)()
Other variant: ADCY9_(TTTA)n, ADCY9_2316A>G
The case-control study using the missense polymorphism, 2316A>G (Ile772Met), and the tetranucleotide repeat (TTTA)n showed no significant association with mood disorders in Japanese samples. Negative Comment on Study
Toyota, T.,2002 Other variant: ADCY9_(TTTA)n, ADCY9_2316A>G In conclusion, our present study revealed weak association of the ADCY9 gene variation with mood disorders in the family-based approach. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 23)

GO terms by PBA (count: 4)

GO terms by database search (count: 19)

Gene related KEGG pathways (count: 6)

KEGG pathways by PBA (count: 3)

KEGG pathways by database search (count: 3)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 2)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 0)

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Region: chr16:3953387..4116185 View in gBrowse
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