SNP Report

Basic Info

Name	rs774026 dbSNP Ensembl
Location	chr12:56428214 - 56428214(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.497005
Functional Annotation	intron_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000229201, ENST00000553532); upstream_gene_variant(ENST00000557589)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Mansour, H. A., 2006	C/T		TDT P-value = 0.314 in the samples combined, Pittsburgh Tren...... TDT P-value = 0.314 in the samples combined, Pittsburgh Trends test=0.835 for BDI More...	The loci tested did not show significant differences between...... The loci tested did not show significant differences between sites in the transmission rate. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TIMELESS	timeless circadian clock	12q13.3	3(0/3/0)

SNPs in LD with rs774026 (count: 0) View in gBrowse (chr12:56428214..56428214 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Mansour, H. A., 2006	TDT P-value = 0.039, X²=4.25, df=1, Trends test=0.352 for Pittsburgh SZ/SZA	When we analyzed transmission bias in the SZ/SZA samples, we observed significant transmission distortion at this loci.	Positive

Overlap with MDD from cross-disorder studies (count: 0)